BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
147841	CC(=O)c1ccc2Sc3ccccc3Nc2c1	InChI=1S/C14H11NOS/c1-9(16)10-6-7-14-12(8-10)15-11-4-2-3-5-13(11)17-14/h2-8,15H,1H3	JWGBOHJGWOPYCL-UHFFFAOYSA-N	42323	1-(10H-phenothiazin-2-yl)ethanone::MLS000047624::SMR000033635::cid_81131	Alpha-2C adrenergic receptor		>10000								PubChem		10.7270/Q2GX491Z		aid504410		PubChem, PC	The Scripps Research Institute Molecular Screening Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42323&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			81131	252623027						ZINC00119687	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155203	COc1ccccc1N1CCN(CCC2C(=O)c3ccccc3C(C)(C)C2=O)CC1	InChI=1S/C25H30N2O3/c1-25(2)20-9-5-4-8-18(20)23(28)19(24(25)29)12-13-26-14-16-27(17-15-26)21-10-6-7-11-22(21)30-3/h4-11,19H,12-17H2,1-3H3	OSEADGVOKYGIER-UHFFFAOYSA-N	81772	ARC-239::CAS_122211::NSC_122211	Alpha-2C adrenergic receptor		 3.82								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81772&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122211	131342346				524		ZINC60027297	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155205	COC(=O)C1=CO[C@@H](C)[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@H]3C[C@H]12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16-,19+/m0/s1	GRTOGORTSDXSFK-BMYCAMMWSA-N	50030622	(7aS,8S,11aS,12aR)-8-Methyl-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester::AKUAMMIGINE::CHEMBL122404	Alpha-2C adrenergic receptor		 28								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030622&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1268096	103939471		CHEMBL122404				ZINC53174616	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155207	CN1C[C@H](Cn2ccnc2-c2ccccc2)C[C@H]2[C@H]1Cc1c(Br)[nH]c3cccc2c13	InChI=1S/C25H25BrN4/c1-29-14-16(15-30-11-10-27-25(30)17-6-3-2-4-7-17)12-19-18-8-5-9-21-23(18)20(13-22(19)29)24(26)28-21/h2-11,16,19,22,28H,12-15H2,1H3/t16-,19-,22-/m1/s1	VKABNRMTNPWHBD-ZWDAVXSWSA-N	81773	BAM 1303::BAM-1303::CAS_115219-10-8	Alpha-2C adrenergic receptor		 0.39								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81773&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10344262	131342347						ZINC38563583	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155209	CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	ZPEIMTDSQAKGNT-UHFFFAOYSA-N	50001888	(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15	Alpha-2C adrenergic receptor		 41								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	Z80	3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX	2726	103916255	3647	CHEMBL71	DB00477	83	C06906	ZINC00044027	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155211	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2C adrenergic receptor		 31								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155213	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2C adrenergic receptor		 12.7								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155215	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2C adrenergic receptor		 10.7								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155217	COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5ccccc45)C3CC12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3	GRTOGORTSDXSFK-UHFFFAOYSA-N	30993	Ajmalicine::MLS000111555::Raubasine::SMR000107477::cid_251561	Alpha-2C adrenergic receptor		 5								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30993&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	AJN	4WNT	251561	242052838							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155219	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2C adrenergic receptor		 0.13								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155221	O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26)	JVGBTTIJPBFLTE-UHFFFAOYSA-N	50020192	8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine	Alpha-2C adrenergic receptor		 0.13								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5268	103931109		CHEMBL300555		53			1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155223	COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1	InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3	UVEKKXRFQCNLQE-UHFFFAOYSA-N	81444	CAS_185453::NSC_185453::WB 4101::WB-4101	Alpha-2C adrenergic receptor		 0.4								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81444&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			14743454	131342018						ZINC14953628	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
155225	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2C adrenergic receptor		 0.3								PDSP Ki		10.7270/Q2WH2NGR	1353247			Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW	University of Nebraska	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
162759	COc1ccccc1N1CCN(CCC2C(=O)c3ccccc3C(C)(C)C2=O)CC1	InChI=1S/C25H30N2O3/c1-25(2)20-9-5-4-8-18(20)23(28)19(24(25)29)12-13-26-14-16-27(17-15-26)21-10-6-7-11-22(21)30-3/h4-11,19H,12-17H2,1-3H3	OSEADGVOKYGIER-UHFFFAOYSA-N	81772	ARC-239::CAS_122211::NSC_122211	Alpha-2C adrenergic receptor		 31.8								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81772&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122211	131342346				524		ZINC60027297	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
162760	COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC(C1)N2C	InChI=1S/C16H22ClN3O2/c1-20-10-3-4-11(20)6-9(5-10)19-16(21)12-7-13(17)14(18)8-15(12)22-2/h7-11H,3-6,18H2,1-2H3,(H,19,21)	HTMNINCXKXABOI-UHFFFAOYSA-N	82519	4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)benzamide::BRL 24682::CAS_76272-78-1	Alpha-2C adrenergic receptor		 150								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82519&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9797313	136350489						ZINC13493298	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
162761	NC(=N)NC(=O)Cc1c(Cl)cccc1Cl	InChI=1S/C9H9Cl2N3O/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13/h1-3H,4H2,(H4,12,13,14,15)	INJOMKTZOLKMBF-UHFFFAOYSA-N	81984	CAS_29110-47-2::Guanfacine::NSC_3519	Alpha-2C adrenergic receptor		 1120								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81984	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81984&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3519	131342558			DB01018	522	C07037	ZINC03872738	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
162762	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2C adrenergic receptor		 185								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
162763	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2C adrenergic receptor		 57.2								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
162764	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2C adrenergic receptor		 0.78								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
162765	COC1(COc2ccccc2O1)C1=NCCN1	InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)	HQGWKNGAKBPTBX-UHFFFAOYSA-N	50019492	(+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::(-)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-ethoxy-idazoxan::CHEMBL10332::RX-821002::RX821002	Alpha-2C adrenergic receptor		 1.78								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019492&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			108094	103930440	73287	CHEMBL10332		528		ZINC03995905	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
162766	O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26)	JVGBTTIJPBFLTE-UHFFFAOYSA-N	50020192	8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine	Alpha-2C adrenergic receptor		 1.04								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5268	103931109		CHEMBL300555		53			1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
162767	COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1	InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3	UVEKKXRFQCNLQE-UHFFFAOYSA-N	81444	CAS_185453::NSC_185453::WB 4101::WB-4101	Alpha-2C adrenergic receptor		 3.18								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81444&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			14743454	131342018						ZINC14953628	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
162768	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2C adrenergic receptor		 3.02								PDSP Ki		10.7270/Q2G73C76	7996470			Uhlen, S; Porter, AC; Neubig, RR	University of Michigan	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176537	Oc1ccc2[C@H](CCCc2c1O)C1=NCCN1	InChI=1S/C13H16N2O2/c16-11-5-4-8-9(12(11)17)2-1-3-10(8)13-14-6-7-15-13/h4-5,10,16-17H,1-3,6-7H2,(H,14,15)/t10-/m0/s1	LYRNYBCBYWDTIF-JTQLQIEISA-N	50019729	(S)-5-(4,5-Dihydro-1H-imidazol-2-yl)-5,6,7,8-tetrahydro-naphthalene-1,2-diol::A-54741::CHEMBL7169	Alpha-2C adrenergic receptor		 776.25								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019729	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019729&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44263962	103930652		CHEMBL7169					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176538	Clc1cccc(Cl)c1N(CC=C)C1=NCCN1	InChI=1S/C12H13Cl2N3/c1-2-8-17(12-15-6-7-16-12)11-9(13)4-3-5-10(11)14/h2-5H,1,6-8H2,(H,15,16)	OXTYVEUAQHPPMV-UHFFFAOYSA-N	85231	Alinidine::CAS_33178-86-8	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85231	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85231&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			36354	136351331						ZINC00003723	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176539	CC(N)C(O)c1ccc(O)c(O)c1	InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3	GEFQWZLICWMTKF-UHFFFAOYSA-N	50027502	4-(2-Amino-1-hydroxy-propyl)-benzene-1,2-diol::Aldoclor-150::Aldoclor-250::CHEMBL764::METHYLNORADRENALINE::alpha-Methyl-(+)norepinephrine,(+/-)::alpha-Methyl-(+/-)norepinephrine,(+/-)::alpha-Methyl-(-)norepinephrine,(+/-)	Alpha-2C adrenergic receptor		 2884.03								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027502&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3917	103936972		CHEMBL764			C17925	ZINC00034160	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176540	Nc1nc2CCN(CC=C)CCc2s1	InChI=1S/C10H15N3S/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8/h2H,1,3-7H2,(H2,11,12)	DHSSDEDRBUKTQY-UHFFFAOYSA-N	86053	B-HT 920::CAS_101626-70-4::CHEMBL279085::NSC_104870::Talipexole::cid_5374	Alpha-2C adrenergic receptor		 954.99								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86053&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5374	136352153		CHEMBL279085				ZINC00006644	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176541	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2C adrenergic receptor		 134.90								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176542	C[C@@H](c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	CUHVIMMYOGQXCV-LLVKDONJSA-N	50241196	(R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole::4-[(R)-1-(2,3-Dimethyl-phenyl)-ethyl]-1H-imidazole::CHEMBL397901::Dexmedetomidine	Alpha-2C adrenergic receptor		 95.50								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241196&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60612	104098658		CHEMBL397901		521		ZINC04676236	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176543	CNCC(O)c1ccc(O)c(O)c1	InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3	UCTWMZQNUQWSLP-UHFFFAOYSA-N	84342	4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol::4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, 1::4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride::4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol;hydrochloride::4-[2-(methylamino)-1-oxidanyl-ethyl]benzene-1,2-diol;hydrochloride::DL-ADRENALINE HYDROCHLORIDE::EPINEPHRINE::EPINEPHRINE,(+)::MLS001333244::SMR000058236::cid_5924	Alpha-2C adrenergic receptor		 1698.24								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	ALE	7BTS,4A7U,7BRN,2HKK,4LDO	838	252659436					C02012	ZINC00039090	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176544	NC(N)=NN=Cc1c(Cl)cccc1Cl	InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14)	WDZVGELJXXEGPV-UHFFFAOYSA-N	81979	CAS_5051-62-7::CAS_65636::Fluprofylline::Guanabenz::NSC_3517::NSC_65636	Alpha-2C adrenergic receptor		 446.68								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81979&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5702063	131342553			DB00629			ZINC03872735	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176545	NC(=N)NC(=O)Cc1c(Cl)cccc1Cl	InChI=1S/C9H9Cl2N3O/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13/h1-3H,4H2,(H4,12,13,14,15)	INJOMKTZOLKMBF-UHFFFAOYSA-N	81984	CAS_29110-47-2::Guanfacine::NSC_3519	Alpha-2C adrenergic receptor		 3890.45								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81984	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81984&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3519	131342558			DB01018	522	C07037	ZINC03872738	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176546	Fc1cccc(Cl)c1C1CN2CCN=C2C1	InChI=1S/C12H12ClFN2/c13-9-2-1-3-10(14)12(9)8-6-11-15-4-5-16(11)7-8/h1-3,8H,4-7H2	VDDKWLCHDOJXJM-UHFFFAOYSA-N	85232	CAS_67249-51-8::ICI 106270	Alpha-2C adrenergic receptor		 281.84								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85232&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			128761	136351332						ZINC06091692	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176547	C1CN=C(N1)C1COc2ccccc2O1	InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	HPMRFMKYPGXPEP-UHFFFAOYSA-N	50019848	2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan	Alpha-2C adrenergic receptor		 19.95								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54459	103930771	5862	CHEMBL10316			C10968	ZINC00900630	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176548	CCn1ccnc1CC1COc2ccccc2O1	InChI=1S/C14H16N2O2/c1-2-16-8-7-15-14(16)9-11-10-17-12-5-3-4-6-13(12)18-11/h3-8,11H,2,9-10H2,1H3	UXABARREKCJULM-UHFFFAOYSA-N	85234	CAS_81167-16-0::IMILOXAN::NSC_133621	Alpha-2C adrenergic receptor		 151.36								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85234&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			133621	136351334				3470		ZINC03995466	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176549	C[C@@H](Oc1c(Cl)cccc1Cl)C1=NCCN1	InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)	KSMAGQUYOIHWFS-UHFFFAOYSA-N	85233	CAS_81447-78-1::Levlofexidine	Alpha-2C adrenergic receptor		 173.78								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85233	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85233&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3038503	136351333	51368					ZINC00005626	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176550	CN1CCC2(CCN3CCc4c(oc5ccccc45)C3C2)N(C)C1=O	InChI=1S/C20H25N3O2/c1-21-11-8-20(22(2)19(21)24)9-12-23-10-7-15-14-5-3-4-6-17(14)25-18(15)16(23)13-20/h3-6,16H,7-13H2,1-2H3	JRDUBBHIPPPSLP-UHFFFAOYSA-N	81811	CAS_123679::L-657,743::MK-912::NSC_123679	Alpha-2C adrenergic receptor		 0.07								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81811&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			123679	131342385						ZINC04475284	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176551	C(C1=NCCN1)c1cccc2ccccc12	InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16)	CNIIGCLFLJGOGP-UHFFFAOYSA-N	50001922	2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; hydrochloride::Albalon::CHEMBL1706::NAPHAZOLINE HYDROCHLORIDE::Nafazair::Naphazoline::Naphazoline Nitrate::Naphcon forte::Opcon::Vasocon::cid_11079	Alpha-2C adrenergic receptor		 407.38								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001922	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001922&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4436	103916289		CHEMBL1706	DB06711		C07898	ZINC00119717	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176552	c1ccc2ccccc2c1	InChI=1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H	UFWIBTONFRDIAS-UHFFFAOYSA-N	50159249	CHEMBL16293::Naphthalen::Naphthalin::naftaleno::naftalina::naphtalene::naphtaline::naphthalene	Alpha-2C adrenergic receptor		 3.31								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159249&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	NPY	7PN4,5VKF,6EKW,1O7G	931	104045832	16482	CHEMBL16293			C00829	ZINC00967522	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176553	NCC(O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2	SFLSHLFXELFNJZ-UHFFFAOYSA-N	35234	DL-[7-3H]norepinephrine::NOREPINEPHRINE::Noradrenaline,(+)::[3H]NE	Alpha-2C adrenergic receptor		 1348.96								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35234&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	951	85753313	33569			484		ZINC00057624	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176554	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2C adrenergic receptor		 239.88								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176555	Nc1cc(Cl)c(NC2=NCCN2)c(Cl)c1	InChI=1S/C9H10Cl2N4/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2,12H2,(H2,13,14,15)	IEJXVRYNEISIKR-UHFFFAOYSA-N	81926	Aminoclonidine, p::CAS_66711-21-5::NSC_51763::p-AMINOCLONIDINE	Alpha-2C adrenergic receptor		 21.38								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81926	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81926&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2216	131342500	2789		DB00964		C07668	ZINC00057175	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176556	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2C adrenergic receptor		 257.04								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176557	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2C adrenergic receptor		 30.90								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176558	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2C adrenergic receptor		 0.55								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176559	C1CC1C(NC1=[NH+]CCO1)C1CC1	InChI=1S/C10H16N2O/c1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10/h7-9H,1-6H2,(H,11,12)/p+1	CQXADFVORZEARL-UHFFFAOYSA-O	50262235	rilmenidine	Alpha-2C adrenergic receptor		 4677.35								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262235&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44577959	104110975					C11120	ZINC00009708	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176560	COC1(COc2ccccc2O1)C1=NCCN1	InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)	HQGWKNGAKBPTBX-UHFFFAOYSA-N	50019492	(+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::(-)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-ethoxy-idazoxan::CHEMBL10332::RX-821002::RX821002	Alpha-2C adrenergic receptor		 0.79								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019492&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			108094	103930440	73287	CHEMBL10332		528		ZINC03995905	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176561	CCc1cccc(CC)c1N=C1NCCN1	InChI=1S/C13H19N3/c1-3-10-6-5-7-11(4-2)12(10)16-13-14-8-9-15-13/h5-7H,3-4,8-9H2,1-2H3,(H2,14,15,16)	IALHTUPVRAQZFI-UHFFFAOYSA-N	85235	CAS_4749-61-5::ST 91::ST-91	Alpha-2C adrenergic receptor		 616.60								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85235&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			20864	136351335						ZINC02037627	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176562	C(C1=NCCN1)c1ccccc1	InChI=1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12)	JIVZKJJQOZQXQB-UHFFFAOYSA-N	55436	2-(phenylmethyl)-4,5-dihydro-1H-imidazole;hydrochloride::2-Benzyl-4,5-dihydro-1H-imidazole::2-benzyl-2-imidazoline;hydrochloride::2-benzyl-4,5-dihydro-1H-imidazole;hydrochloride::MLS000559484::SMR000149600::Tolazoline::cid_6048	Alpha-2C adrenergic receptor		 3715.35								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55436&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5504	252635433	28502		DB00797		C07147	ZINC00125006	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176563	C1CNC(N1)=Nc1cccc2CCCCc12	InChI=1S/C13H17N3/c1-2-6-11-10(4-1)5-3-7-12(11)16-13-14-8-9-15-13/h3,5,7H,1-2,4,6,8-9H2,(H2,14,15,16)	QQJLHRRUATVHED-UHFFFAOYSA-N	50027056	(4,5-Dihydro-1H-imidazol-2-yl)-(5,6,7,8-tetrahydro-naphthalen-1-yl)-amine::CHEMBL32573::Imidazolidin-2-ylidene-(5,6,7,8-tetrahydro-naphthalen-1-yl)-amine::Tramazoline	Alpha-2C adrenergic receptor		 275.42								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027056	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027056&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5524	103936638		CHEMBL32573				ZINC01534528	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176564	Brc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	XYLJNLCSTIOKRM-UHFFFAOYSA-N	34572	BRIMONIDINE::CHEMBL844::MLS000069370::SMR000058355::UK 14,304::cid_2435	Alpha-2C adrenergic receptor		 1949.84								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34572&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J59	7EJ8	2435	252617225	3175	CHEMBL844	DB00484	520	C07886	ZINC21303210	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176565	Cc1cccc(C)c1N=C1NCCCS1	InChI=1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)	BPICBUSOMSTKRF-UHFFFAOYSA-N	50027069	(2,6-Dimethyl-phenyl)-[1,3]thiazinan-2-ylidene-amine::(5,6-Dihydro-4H-[1,3]thiazin-2-yl)-(2,6-dimethyl-phenyl)-amine::CHEMBL297362::Xylazine	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027069	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027069&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5707	103936651		CHEMBL297362		523		ZINC00002248	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
176566	Cc1cc(cc(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15/h8-9H,6-7,10H2,1-5H3,(H,17,18)	HUCJFAOMUPXHDK-UHFFFAOYSA-N	30703	2-(4-tert-butyl-2,6-dimethyl-benzyl)-2-imidazoline;hydrochloride::2-[(4-tert-butyl-2,6-dimethyl-phenyl)methyl]-4,5-dihydro-1H-imidazole;hydrochloride::2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole;hydrochloride::CHEMBL312448::MLS000069695::SMR000058526::XYLOMETAZOLINE HYDROCHLORIDE::Xylometazoline::cid_5282386	Alpha-2C adrenergic receptor		 128.82								PDSP Ki	10.1016/s0006-2952(97)00631-x	10.7270/Q2T72G01	9605427			Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM	Roche Bioscience	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30703&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5709	252614962		CHEMBL312448	DB06694		C07913	ZINC00057534	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172922	Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12	InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3	PMXMIIMHBWHSKN-UHFFFAOYSA-N	50252513	3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE	Alpha-2C adrenergic receptor		 11								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	K4I		115237	104105311		CHEMBL1621	DB01267	7258		ZINC04214700	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172923	CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1	InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3	ZUXABONWMNSFBN-UHFFFAOYSA-N	22869	6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine	Alpha-2C adrenergic receptor		 9.1								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2818	49846683				38		ZINC19796155	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172924	Fc1ccc(cc1)C(CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(F)cc1	InChI=1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35)	QOYHHIBFXOOADH-UHFFFAOYSA-N	26948	8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL46516::FLUSPIRILENE::NCGC00015424::cid_3396::med.21724, Compound Fluspirilene::spiropiperidine analogue, 1	Alpha-2C adrenergic receptor		 62								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26948	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26948&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3396	57298659		CHEMBL46516	DB04842	85		ZINC00537755	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172925	OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1	InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	LNEPOXFFQSENCJ-UHFFFAOYSA-N	21398	4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1	Alpha-2C adrenergic receptor		 550								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	GMJ	6X10,6DJZ,6LUQ	3559	49689470	5613	CHEMBL54CHEMBL545608	DB00502	86	C01814	ZINC00537822	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172926	CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1	InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3	WXPNDRBBWZMPQG-UHFFFAOYSA-N	82479	CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2	Alpha-2C adrenergic receptor		 210								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4585	136350450				47		ZINC03873830	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172927	CN1CC2C(C1)c1cc(Cl)ccc1Oc1ccccc21	InChI=1S/C17H16ClNO/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19/h2-8,14-15H,9-10H2,1H3	VSWBSWWIRNCQIJ-UHFFFAOYSA-N	84994	CAS_163091::NSC_163091::ORG-5222	Alpha-2C adrenergic receptor		 13								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84994&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9903970	136351094	71255		DB06216			ZINC11677376	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172928	NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N1CCCCC1	InChI=1S/C21H30FN3O2/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25/h6-9H,1-5,10-16H2,(H2,23,27)	AXKPFOAXAHJUAG-UHFFFAOYSA-N	81483	CAS_1893-33-0::NSC_4830::PIPAMPERONE	Alpha-2C adrenergic receptor		 290								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81483&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4830	131342057			DB09286	92		ZINC21297287	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172929	OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12	InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2	URKOMYMAXPYINW-UHFFFAOYSA-N	50095890	2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE	Alpha-2C adrenergic receptor		 350								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5002	103993497	8707	CHEMBL716	DB01224	50	C07397	ZINC19632628	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172930	Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12	InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	RAPZEAPATHNIPO-UHFFFAOYSA-N	50001885	(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone	Alpha-2C adrenergic receptor		 9.1								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	8NU	6A93,6CM4	5073	103916252	8871	CHEMBL85	DB00734	96		ZINC00538312	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172931	Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12	InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	GZKLJWGUPQBVJQ-UHFFFAOYSA-N	50001786	1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole	Alpha-2C adrenergic receptor		 450								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60149	103916159	9122	CHEMBL12713	DB06144	98	C07567	ZINC00538337	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172932	O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26)	JVGBTTIJPBFLTE-UHFFFAOYSA-N	50020192	8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine	Alpha-2C adrenergic receptor		 0.4								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5268	103931109		CHEMBL300555		53			1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172933	Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12	InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)	MVWVFYHBGMAFLY-UHFFFAOYSA-N	50048803	5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE	Alpha-2C adrenergic receptor		 77								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60854	103979184	10119	CHEMBL708	DB00246	59	C07568	ZINC00538550	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
172934	CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3	HDOZVRUNCMBHFH-UHFFFAOYSA-N	35255	2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin::2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin::2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine::CHEMBL285802::Nipolept::Zoleptil::zotepine	Alpha-2C adrenergic receptor		 150								PDSP Ki	10.1007/bf02245606	10.7270/Q2610XV6	8935801			Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35255&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	ZOT	6A94	5736	85753334	32316	CHEMBL285802	DB09225	103		ZINC00002264	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51221293	CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12	InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)	WHTVZRBIWZFKQO-UHFFFAOYSA-N	22985	Aralen::CHEMBL76::CHLOROQUINE PHOSPHATE::Chlorochin::Chloroquine::Chloroquine, 17::med.21724, Compound 8::{4-[(7-chloroquinolin-4-yl)amino]pentyl}diethylamine	Alpha-2C adrenergic receptor		 10000								ChEMBL	10.1038/s41586-020-2286-9	10.7270/Q29Z984K	32353859			Gordon, DE; Jang, GM; Bouhaddou, M; Xu, J; Obernier, K; White, KM; O'Meara, MJ; Rezelj, VV; Guo, JZ; Swaney, DL; Tummino, TA; Hüttenhain, R; Kaake, RM; Richards, AL; Tutuncuoglu, B; Foussard, H; Batra, J; Haas, K; Modak, M; Kim, M; Haas, P; Polacco, BJ; Braberg, H; Fabius, JM; Eckhardt, M; Soucheray, M; Bennett, MJ; Cakir, M; McGregor, MJ; Li, Q; Meyer, B; Roesch, F; Vallet, T; Mac Kain, A; Miorin, L; Moreno, E; Naing, ZZC; Zhou, Y; Peng, S; Shi, Y; Zhang, Z; Shen, W; Kirby, IT; Melnyk, JE; Chorba, JS; Lou, K; Dai, SA; Barrio-Hernandez, I; Memon, D; Hernandez-Armenta, C; Lyu, J; Mathy, CJP; Perica, T; Pilla, KB; Ganesan, SJ; Saltzberg, DJ; Rakesh, R; Liu, X; Rosenthal, SB; Calviello, L; Venkataramanan, S; Liboy-Lugo, J; Lin, Y; Huang, XP; Liu, Y; Wankowicz, SA; Bohn, M; Safari, M; Ugur, FS; Koh, C; Savar, NS; Tran, QD; Shengjuler, D; Fletcher, SJ; O'Neal, MC; Cai, Y; Chang, JCJ; Broadhurst, DJ; Klippsten, S; Sharp, PP; Wenzell, NA; Kuzuoglu-Ozturk, D; Wang, HY; Trenker, R; Young, JM; Cavero, DA; Hiatt, J; Roth, TL; Rathore, U; Subramanian, A; Noack, J; Hubert, M; Stroud, RM; Frankel, AD; Rosenberg, OS; Verba, KA; Agard, DA; Ott, M; Emerman, M; Jura, N; von Zastrow, M; Verdin, E; Ashworth, A; Schwartz, O; d'Enfert, C; Mukherjee, S; Jacobson, M; Malik, HS; Fujimori, DG; Ideker, T; Craik, CS; Floor, SN; Fraser, JS; Gross, JD; Sali, A; Roth, BL; Ruggero, D; Taunton, J; Kortemme, T; Beltrao, P; Vignuzzi, M; García-Sastre, A; Shokat, KM; Shoichet, BK; Krogan, NJ	QBI COVID-19 Research Group (QCRG)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22985	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22985&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	0TX	7ER3,4FGK	2719	49846799	3638	CHEMBL76	DB00608	5535	C07625	ZINC01530861	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
182154	COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(N)c2CCOc12	InChI=1S/C18H26ClN3O3/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23)	ZPMNHBXQOOVQJL-UHFFFAOYSA-N	50122872	4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide::CHEMBL117287::PRUCALOPRIDE::US9663465, prucalopride	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1016/s0014-2999(01)01087-1	10.7270/Q23T9FSX	11438309			Briejer, MR; Bosmans, JP; Van Daele, P; Jurzak, M; Heylen, L; Leysen, JE; Prins, NH; Schuurkes, JA	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122872	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122872&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3052762	104015490		CHEMBL117287	DB06480	243		ZINC01891034	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
182409	CC(CF)NCC(O)COc1cccc2[nH]c3ccccc3c12	InChI=1S/C18H21FN2O2/c1-12(9-19)20-10-13(22)11-23-17-8-4-7-16-18(17)14-5-2-3-6-15(14)21-16/h2-8,12-13,20-22H,9-11H2,1H3	QHLGXPUIUKSADT-UHFFFAOYSA-N	85818	Fluorocarazolol,(R)::Fluorocarazolol,(S)	Alpha-2C adrenergic receptor		 1890								PDSP Ki	10.1007/s002130100844	10.7270/Q22V2DPJ	11512051			Roth, BL; Ernsberger, P; Steinberg, SA; Rao, S; Rauser, L; Savage, J; Hufeisen, S; Berridge, MS; Muzic, RF	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85818&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			133038	136351918						ZINC06036510	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
182410	CC(CF)NCC(O)COc1cccc2[nH]c3ccccc3c12	InChI=1S/C18H21FN2O2/c1-12(9-19)20-10-13(22)11-23-17-8-4-7-16-18(17)14-5-2-3-6-15(14)21-16/h2-8,12-13,20-22H,9-11H2,1H3	QHLGXPUIUKSADT-UHFFFAOYSA-N	85818	Fluorocarazolol,(R)::Fluorocarazolol,(S)	Alpha-2C adrenergic receptor		 4400								PDSP Ki	10.1007/s002130100844	10.7270/Q22V2DPJ	11512051			Roth, BL; Ernsberger, P; Steinberg, SA; Rao, S; Rauser, L; Savage, J; Hufeisen, S; Berridge, MS; Muzic, RF	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85818&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			133038	136351918						ZINC06036510	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
180046	Fc1cccc2OC3CNCC3Oc12	InChI=1S/C10H10FNO2/c11-6-2-1-3-7-10(6)14-9-5-12-4-8(9)13-7/h1-3,8-9,12H,4-5H2	XSOUHEXVEOQRKJ-UHFFFAOYSA-N	85595	CAS_105182-45-4::Fluparoxan::NSC_72036	Alpha-2C adrenergic receptor		 1.58								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85595&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10219795	136351695				41		ZINC11680328	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
180047	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2C adrenergic receptor		 5.01								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
180048	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2C adrenergic receptor		 0.25								PDSP Ki	10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X	10.7270/Q2XK8D4N	10611634			Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
181310	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2C adrenergic receptor		 501.1872								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
181311	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2C adrenergic receptor		 63.0957								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
181312	C[C@@H](c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	CUHVIMMYOGQXCV-LLVKDONJSA-N	50241196	(R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole::4-[(R)-1-(2,3-Dimethyl-phenyl)-ethyl]-1H-imidazole::CHEMBL397901::Dexmedetomidine	Alpha-2C adrenergic receptor		 15.1356								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241196&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60612	104098658		CHEMBL397901		521		ZINC04676236	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
181313	C[C@@H](c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m1/s1	CUHVIMMYOGQXCV-LLVKDONJSA-N	50241196	(R)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole::4-[(R)-1-(2,3-Dimethyl-phenyl)-ethyl]-1H-imidazole::CHEMBL397901::Dexmedetomidine	Alpha-2C adrenergic receptor		 2.5119								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241196&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60612	104098658		CHEMBL397901		521		ZINC04676236	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
181314	NCC(O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2	SFLSHLFXELFNJZ-UHFFFAOYSA-N	35234	DL-[7-3H]norepinephrine::NOREPINEPHRINE::Noradrenaline,(+)::[3H]NE	Alpha-2C adrenergic receptor		 588.8437								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35234&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	951	85753313	33569			484		ZINC00057624	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
181315	NC1=NC2(CO1)CCc1ccccc1C2	InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14)	ZFZUYTCCHMWWTD-UHFFFAOYSA-N	85709	S18616	Alpha-2C adrenergic receptor		 6.0256								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85709&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10442840	136351809						ZINC13743776	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
181316	NC1=NC2(CO1)CCc1ccccc1C2	InChI=1S/C12H14N2O/c13-11-14-12(8-15-11)6-5-9-3-1-2-4-10(9)7-12/h1-4H,5-8H2,(H2,13,14)	ZFZUYTCCHMWWTD-UHFFFAOYSA-N	85709	S18616	Alpha-2C adrenergic receptor		 0.3462								PDSP Ki		10.7270/Q28P5Z2C	11082457			Millan, MJ; Dekeyne, A; Newman-Tancredi, A; Cussac, D; Audinot, V; Milligan, G; Duqueyroix, D; Girardon, S; Mullot, J; Boutin, JA; Nicolas, JP; Renouard-Try, A; Lacoste, JM; Cordi, A	Centre de Recherches de Croissy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85709&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10442840	136351809						ZINC13743776	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
182023	C(N1CCN(CC1)c1ncccn1)c1ccc2OCOc2c1	InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2	OQDPVLVUJFGPGQ-UHFFFAOYSA-N	85092	CAS_3605-01-4::NSC_4850::Piribedil	Alpha-2C adrenergic receptor		 69.18								PDSP Ki		10.7270/Q2W957RF	11356907			Millan, MJ; Cussac, D; Milligan, G; Carr, C; Audinot, V; Gobert, A; Lejeune, F; Rivet, JM; Brocco, M; Duqueyroix, D; Nicolas, JP; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85092	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85092&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4850	136351192						ZINC19537374	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
183726	Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1	InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H	QYDURWHTEIUTEI-UHFFFAOYSA-N	50129952	2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one::8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxy-phenyl]-5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one::Amentoflavone::CHEMBL63354::cid_5281600	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129952	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129952&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5281600	104021411	2631	CHEMBL63354				ZINC03984030	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
183727	CC(C)C(=O)[C@]12C(=O)C(CC=C(C)C)C(=O)[C@@](CC=C(C)C)(C[C@H](CC=C(C)C)[C@@]1(C)CCC=C(C)C)C2=O	InChI=1S/C35H52O4/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10/h13-15,18,26-28H,12,16-17,19-21H2,1-11H3/t27-,28?,33+,34+,35+/m0/s1	GQRREYKSPJMLAW-CWRBZUMDSA-N	50242259	CHEMBL516641::HYPERFORIN	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242259&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91935559	104099004		CHEMBL516641					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
183728	Cc1cc(O)c2c3c1c1c(CO)cc(O)c4c1c1c5c(c(O)cc(O)c5c4=O)c4c(O)cc(O)c(c4c31)c2=O	InChI=1S/C30H16O9/c1-7-2-9(32)19-23-15(7)16-8(6-31)3-10(33)20-24(16)28-26-18(12(35)5-14(37)22(26)30(20)39)17-11(34)4-13(36)21(29(19)38)25(17)27(23)28/h2-5,31-37H,6H2,1H3	YXBUQQDFTYOHQI-UHFFFAOYSA-N	50333880	CHEMBL1614664::Hypericin::Pseudohypericin	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50333880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50333880&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5281751	125083982		CHEMBL1614664			C10392	ZINC03917574	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
183729	OCC1OC(Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)C(O)C(O)C1O	InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-25,27-30H,6H2	DPFYPHSPTUZJJT-UHFFFAOYSA-N	86036	CAS_5318390::CAS_97331::Hyperoside::Miquelianin::NSC_5318390::NSC_97331	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86036&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5378597	136352136						ZINC05004613	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184867	COc1ccc2ccccc2c1CCCCN1CCN(C[C@@H](N2CCN(CC2)C(C)C)c2ccc(F)cc2)CC1	InChI=1S/C34H47FN4O/c1-27(2)38-22-24-39(25-23-38)33(29-11-14-30(35)15-12-29)26-37-20-18-36(19-21-37)17-7-6-10-32-31-9-5-4-8-28(31)13-16-34(32)40-3/h4-5,8-9,11-16,27,33H,6-7,10,17-26H2,1-3H3/t33-/m1/s1	SLGLZEJKMBCODK-MGBGTMOVSA-N	86058	MCL0129	Alpha-2C adrenergic receptor		 1000								PDSP Ki	10.1124/jpet.102.044826	10.7270/Q2FQ9V5W	12538838			Chaki, S; Hirota, S; Funakoshi, T; Suzuki, Y; Suetake, S; Okubo, T; Ishii, T; Nakazato, A; Okuyama, S	Taisho Pharmaceutical Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86058&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6918688	136352158						ZINC22453554	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184905	CCn1c2nocc2c(=O)[nH]c1=O	InChI=1S/C7H7N3O3/c1-2-10-5-4(3-13-9-5)6(11)8-7(10)12/h3H,2H2,1H3,(H,8,11,12)	GTMGELLVPUSBMG-UHFFFAOYSA-N	86061	A-304121	Alpha-2C adrenergic receptor		 2884.03								PDSP Ki	10.1124/jpet.102.047183	10.7270/Q22J69FK	12606603			Esbenshade, TA; Krueger, KM; Miller, TR; Kang, CH; Denny, LI; Witte, DG; Yao, BB; Fox, GB; Faghih, R; Bennani, YL; Williams, M; Hancock, AA	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86061	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86061&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			327764	136352161				1258		ZINC01567523	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184906	C[C@@H](NC(=O)c1ccco1)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1	InChI=1S/C25H31N3O5/c1-18(26-24(30)22-4-2-16-33-22)25(31)28-14-12-27(13-15-28)11-3-17-32-21-9-7-20(8-10-21)23(29)19-5-6-19/h2,4,7-10,16,18-19H,3,5-6,11-15,17H2,1H3,(H,26,30)/t18-/m1/s1	RTRADBQSZJIRMT-GOSISDBHSA-N	50158601	A-317920::CHEMBL361355::Furan-2-carboxylic acid ((R)-2-{4-[3-(4-cyclopropanecarbonyl-phenoxy)-propyl]-piperazin-1-yl}-1-methyl-2-oxo-ethyl)-amide	Alpha-2C adrenergic receptor		 2398.83								PDSP Ki	10.1124/jpet.102.047183	10.7270/Q22J69FK	12606603			Esbenshade, TA; Krueger, KM; Miller, TR; Kang, CH; Denny, LI; Witte, DG; Yao, BB; Fox, GB; Faghih, R; Bennani, YL; Williams, M; Hancock, AA	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158601&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10389213	104045280		CHEMBL361355		1216		ZINC28119372	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184907	O=C(C1CC1)c1ccc(OCCCc2cnc[nH]2)cc1	InChI=1S/C16H18N2O2/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14/h5-8,10-12H,1-4,9H2,(H,17,18)	ACQBHJXEAYTHCY-UHFFFAOYSA-N	27213	4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole::CHEMBL14638::CHEMBL1795025::Ciproxifan	Alpha-2C adrenergic receptor		 63.10								PDSP Ki	10.1124/jpet.102.047183	10.7270/Q22J69FK	12606603			Esbenshade, TA; Krueger, KM; Miller, TR; Kang, CH; Denny, LI; Witte, DG; Yao, BB; Fox, GB; Faghih, R; Bennani, YL; Williams, M; Hancock, AA	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27213	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27213&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6422124	57298923		CHEMBL14638CHEMBL1795025		1265		ZINC01892860	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184908	NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1	InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19)	UCAIEVHKDLMIFL-UHFFFAOYSA-N	22541	Clobenpropit::N''-[(4-chlorophenyl)methyl]{[3-(1H-imidazol-5-yl)propyl]sulfanyl}methanimidamide::VUF 9153::VUF-9153::VUF9153	Alpha-2C adrenergic receptor		 15.85								PDSP Ki	10.1124/jpet.102.047183	10.7270/Q22J69FK	12606603			Esbenshade, TA; Krueger, KM; Miller, TR; Kang, CH; Denny, LI; Witte, DG; Yao, BB; Fox, GB; Faghih, R; Bennani, YL; Williams, M; Hancock, AA	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22541&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2790	49846355				1223		ZINC14951170	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184909	S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1	InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)	QKDDJDBFONZGBW-UHFFFAOYSA-N	22914	CHEMBL260374::N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide::Thioperamide::US11622967, Compound Thioperamide	Alpha-2C adrenergic receptor		 346.74								PDSP Ki	10.1124/jpet.102.047183	10.7270/Q22J69FK	12606603			Esbenshade, TA; Krueger, KM; Miller, TR; Kang, CH; Denny, LI; Witte, DG; Yao, BB; Fox, GB; Faghih, R; Bennani, YL; Williams, M; Hancock, AA	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22914	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22914&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	FJZ	3MDM	3035905	49846728		CHEMBL260374		1267		ZINC13108134	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
183730	OCC1OC(O)C(Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)C(O)C1O	InChI=1S/C21H20O12/c22-6-13-15(27)17(29)20(21(30)32-13)33-19-16(28)14-11(26)4-8(23)5-12(14)31-18(19)7-1-2-9(24)10(25)3-7/h1-5,13,15,17,20-25,27-30H,6H2	JDCKEYDYTNBCCS-UHFFFAOYSA-N	84979	Isoquercitrin	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84979&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57339948	136351079						ZINC86865007	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
183731	OCC1OC(Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)C(O)C(O)C1O	InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-25,27-30H,6H2	DPFYPHSPTUZJJT-UHFFFAOYSA-N	86036	CAS_5318390::CAS_97331::Hyperoside::Miquelianin::NSC_5318390::NSC_97331	Alpha-2C adrenergic receptor		 4063								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86036&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5378597	136352136						ZINC05004613	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
183732	Cc1cc(O)c2c3c1c1c(CO)cc(O)c4c1c1c5c(c(O)cc(O)c5c4=O)c4c(O)cc(O)c(c4c31)c2=O	InChI=1S/C30H16O9/c1-7-2-9(32)19-23-15(7)16-8(6-31)3-10(33)20-24(16)28-26-18(12(35)5-14(37)22(26)30(20)39)17-11(34)4-13(36)21(29(19)38)25(17)27(23)28/h2-5,31-37H,6H2,1H3	YXBUQQDFTYOHQI-UHFFFAOYSA-N	50333880	CHEMBL1614664::Hypericin::Pseudohypericin	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50333880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50333880&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5281751	125083982		CHEMBL1614664			C10392	ZINC03917574	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
183733	Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O	InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H	REFJWTPEDVJJIY-UHFFFAOYSA-N	7460	2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate::CHEMBL50::Quercetin::Quercetin (10)::Quercetin (21)::Quercetin (Qur)::US11021454, Compound Quercetin::US9180183, Quercetin::med.21724, Compound 4	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7460	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=7460&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	QUE	3BPT,2HCK,3LJ0,4LMU,5FLI,5FLJ,3CF8,4DFU,4MRA,4WNJ,2O3P,2MS6,5AUW,3BXX,6M89,3LM5,1GP6,6AWS,6QCN,6QCD,7VUM,6B1D,2N6C,1E8W,2C9Z,5XG4,5A4V,2UXH,1H1I,2JJ2,6TTA,6IJD,3NVY	5280343	11108251	16243	CHEMBL50	DB04216	5346	C00389	ZINC03869685	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
183734	C[C@@H]1O[C@@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O	InChI=1S/C21H20O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-18,21-24,26-29H,1H3/t7-,15-,17+,18+,21-/m0/s1	XHIUPRGKXRAZCR-HQBVPOQASA-N	84978	Quercitrin::cid_5280459	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84978	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84978&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5280459	136351078	17558				C02757	ZINC04175638	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
183735	C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(O)c4c(cc(O)cc4=O)oc3-c3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O	InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-30,32-38H,7H2,1H3/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-/m0/s1	HRFGZDXDXWODFE-NVPNHPEKSA-N	50217942	2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside::3-Rhamnoglucosylquercetin::3-Rutinosyl quercetin::CHEMBL226335::cid_5280805::rutin	Alpha-2C adrenergic receptor		 9637								PDSP Ki	10.1007/s00213-002-1073-7	10.7270/Q25D8QDD	12110997			Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL	Westf&auml;lische Wilhelms-Universit&auml; Muenster,	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217942	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217942&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	RUT	1RY8	5280805	104091802	28527	CHEMBL226335			C02757	ZINC04096846	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
182747	COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O	InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3	XMXHEBAFVSFQEX-UHFFFAOYSA-N	50034043	1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14376::ILOPERIDONE	Alpha-2C adrenergic receptor		 16.2								PDSP Ki	10.1016/S0893-133X(01)00285-8	10.7270/Q21V5CHQ	11750183			Kalkman, HO; Subramanian, N; Hoyer, D	Novartis Pharma	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034043&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71360	103942259	65173	CHEMBL14376	DB04946	87		ZINC01548097	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
186526	CNC(C)Cc1ccc2OCOc2c1	InChI=1S/C11H15NO2/c1-8(12-2)5-9-3-4-10-11(6-9)14-7-13-10/h3-4,6,8,12H,5,7H2,1-2H3	SHXWCVYOXRDMCX-UHFFFAOYSA-N	50010588	(RS)-3,4-(methylenedioxy)methamphetamine::1-(1,3-Benzodioxol-5-yl)-N-methyl-2-propanamine::1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine::3,4-methylenedioxymethamphetamine::CHEMBL43048::DL-(3,4-Methylenedioxy)methamphetamine::MDMA::N,alpha-dimethyl-1,3-benzodioxole-5-ethanamine::N-Methyl-3,4-methylenedioxyamphetamine	Alpha-2C adrenergic receptor		 1123								PDSP Ki	10.1124/mol.63.6.1223	10.7270/Q2FN14SJ	12761331			Setola, V; Hufeisen, SJ; Grande-Allen, KJ; Vesely, I; Glennon, RA; Blough, B; Rothman, RB; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010588&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	B41	3GM0	1615	103923364	1391	CHEMBL43048	DB01454	4574	C07577	ZINC00403053	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185423	Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl	InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	CEUORZQYGODEFX-UHFFFAOYSA-N	50130293	7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole	Alpha-2C adrenergic receptor		 37								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	9SC	7VR9,7E2Z,6A7P,7VOE,7WKZ	60795	104021727	31236	CHEMBL1112	DB01238	34	C12564	ZINC01851149	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185424	CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12	InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	ZPEIMTDSQAKGNT-UHFFFAOYSA-N	50001888	(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15	Alpha-2C adrenergic receptor		 46								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	Z80	3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX	2726	103916255	3647	CHEMBL71	DB00477	83	C06906	ZINC00044027	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185425	CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1	InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3	ZUXABONWMNSFBN-UHFFFAOYSA-N	22869	6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine	Alpha-2C adrenergic receptor		 34								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2818	49846683				38		ZINC19796155	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185426	OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1	InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2	PLDUPXSUYLZYBN-UHFFFAOYSA-N	78433	2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17	Alpha-2C adrenergic receptor		 28.8								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3372	252655189			DB00623		C07010	ZINC19203912	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185427	OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1	InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	LNEPOXFFQSENCJ-UHFFFAOYSA-N	21398	4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1	Alpha-2C adrenergic receptor		 550								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	GMJ	6X10,6DJZ,6LUQ	3559	49689470	5613	CHEMBL54CHEMBL545608	DB00502	86	C01814	ZINC00537822	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185428	CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12	InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3	XJGVXQDUIWGIRW-UHFFFAOYSA-N	22871	13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine	Alpha-2C adrenergic receptor		 79.9								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3964	49846685	50841	CHEMBL831	DB00408	205	C07104	ZINC19796158	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185429	CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12	InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3	KLPWJLBORRMFGK-UHFFFAOYSA-N	50130290	3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban	Alpha-2C adrenergic receptor		 172.6								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23897	104021724		CHEMBL460	DB01618	207	C07230	ZINC22002218	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
186625	Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl	InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	CEUORZQYGODEFX-UHFFFAOYSA-N	50130293	7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole	Alpha-2C adrenergic receptor		 37.9								PDSP Ki	10.1038/sj.npp.1300203	10.7270/Q2639N9T	12784105			Shapiro, DA; Renock, S; Arrington, E; Chiodo, LA; Liu, LX; Sibley, DR; Roth, BL; Mailman, R	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	9SC	7VR9,7E2Z,6A7P,7VOE,7WKZ	60795	104021727	31236	CHEMBL1112	DB01238	34	C12564	ZINC01851149	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185431	OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1	InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2	RGCVKNLCSQQDEP-UHFFFAOYSA-N	50130273	2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine	Alpha-2C adrenergic receptor		 85.2								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130273&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4748	104021707	8028	CHEMBL567	DB00850	209	C07427	ZINC19228902	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185432	Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1	InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)	YVUQSNJEYSNKRX-UHFFFAOYSA-N	50334150	1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238	Alpha-2C adrenergic receptor		 376.5								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	1II	7WLL	16362	125084252	8212	CHEMBL1423	DB01100	90	C07566	ZINC19796084	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185433	OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12	InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2	URKOMYMAXPYINW-UHFFFAOYSA-N	50095890	2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE	Alpha-2C adrenergic receptor		 28.7								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5002	103993497	8707	CHEMBL716	DB01224	50	C07397	ZINC19632628	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185434	Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12	InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	RAPZEAPATHNIPO-UHFFFAOYSA-N	50001885	(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone	Alpha-2C adrenergic receptor		 1.3								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	8NU	6A93,6CM4	5073	103916252	8871	CHEMBL85	DB00734	96		ZINC00538312	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185435	Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12	InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31)	GZKLJWGUPQBVJQ-UHFFFAOYSA-N	50001786	1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole	Alpha-2C adrenergic receptor		 450								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60149	103916159	9122	CHEMBL12713	DB06144	98	C07567	ZINC00538337	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185436	CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1	InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3	KLBQZWRITKRQQV-UHFFFAOYSA-N	50002338	(Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine	Alpha-2C adrenergic receptor		 74.8								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LZU	4I1R,4UHX	5452	103916644	9566	CHEMBL479	DB00679	100		ZINC01530697	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185437	CN(C)S(=O)(=O)c1ccc2Sc3ccccc3C(=CCCN3CCN(C)CC3)c2c1	InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3	GFBKORZTTCHDGY-UHFFFAOYSA-N	86187	CAS_22189-31-7::NSC_5454::THIOTHIXENE	Alpha-2C adrenergic receptor		 51.9								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86187&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			941650	136352287						ZINC29747244	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185438	CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1	InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3	ZEWQUBUPAILYHI-UHFFFAOYSA-N	79181	10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566	Alpha-2C adrenergic receptor		 391.5								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TFP	4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0	5566	252655893			DB00831		C07168	ZINC19418959	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185439	Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12	InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)	MVWVFYHBGMAFLY-UHFFFAOYSA-N	50048803	5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE	Alpha-2C adrenergic receptor		 59								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60854	103979184	10119	CHEMBL708	DB00246	59	C07568	ZINC00538550	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185430	CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1	InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3	WXPNDRBBWZMPQG-UHFFFAOYSA-N	82479	CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2	Alpha-2C adrenergic receptor		 28.8								PDSP Ki	10.1038/sj.npp.1300027	10.7270/Q2833QKK	12629531			Kroeze, WK; Hufeisen, SJ; Popadak, BA; Renock, SM; Steinberg, S; Ernsberger, P; Jayathilake, K; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4585	136350450				47		ZINC03873830	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185712	NC(CSSCC(N)C(O)=O)C(O)=O	InChI=1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)	LEVWYRKDKASIDU-UHFFFAOYSA-N	86199	CAS_595::CAS_67678::D-cystine::L-cystine::NSC_595::NSC_67678	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86199&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	IYY	8DKM,7ZKW	595	136352299	17376				C01420	ZINC01532673	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185713	N[C@H](CCS(O)(=O)=O)C(O)=O	InChI=1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m1/s1	VBOQYPQEPHKASR-GSVOUGTGSA-N	86196	D-homocysteic acid	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86196&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			185861	136352296					C15521	ZINC02545126	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185714	N[C@H](CCS(O)=O)C(O)=O	InChI=1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m1/s1	PDNJLMZEGXHSCU-GSVOUGTGSA-N	86197	D-homocysteine sulfinic acid	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86197&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23844143	136352297					C01615	ZINC25720437	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185715	N[C@@H]1CCSC1=O	InChI=1S/C4H7NOS/c5-3-1-2-7-4(3)6/h3H,1-2,5H2/t3-/m1/s1	KIWQWJKWBHZMDT-GSVOUGTGSA-N	86205	D-homocysteine thiolactone	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86205	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86205&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			7057932	136352305						ZINC54009854	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185716	CSCCC(N)C(O)=O	InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)	FFEARJCKVFRZRR-UHFFFAOYSA-N	86195	CAS_6137::CAS_84815::D-methionine::L-methionine::NSC_6137::NSC_84815	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86195&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	MED	4GLS,4GLU,1Y9Q,1ZUE,5CGO,5CGN,1TKJ,6CNU,3TRY,7P5R,6DZX,3GP4,3TRV,8F16,6WI3,6JV7,4OIJ,4OIK,6PHQ,6PHN,6PHM,1KQ0,5I5A,5I5B,6WKB,2Q33,7UO8,5HHD,5XPK,3TJW,5I1P,5I1S,5I1O,5I1N	876	136352295	16811				C01733	ZINC01532766	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185717	NC(CCS(O)(=O)=O)C(O)=O	InChI=1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)	VBOQYPQEPHKASR-UHFFFAOYSA-N	50164447	2-amino-4-sulfobutanoic acid::CHEMBL191727::DL-homocysteic acid	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164447&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	HJT	6Q6J	92117	104050228		CHEMBL191727			C15521	ZINC02567965	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185718	NC(CCS)C(O)=O	InChI=1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)	FFFHZYDWPBMWHY-UHFFFAOYSA-N	86202	CAS_778::DL-homocysteine::NSC_778	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86202&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	HCS	4YGW,3BOF,4HPD,2N0I,3BQ5,1Q8J,2LP2,4M3P,4L6H,2CI5,1U22,3BOL,3VK4,5OTT,5OTU,5OTV,5OTW,4L5Z,1JVI,6IQG,6R28,5F2Y,5WT5,4XFI,4XFA,4XF9,4XF4,1JQW,1XDJ,8BIX,4QQU,5X30,4PIZ,4PIY,5DMM,1Q8A,6VJU,6PO4,7F1V	778	136352302	17230				C05330	ZINC00895703	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185719	NC(CS(O)(=O)=O)C(O)=O	InChI=1S/C3H7NO5S/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)	XVOYSCVBGLVSOL-UHFFFAOYSA-N	85473	L-Cysteic acid, 8::L-cysteic acid	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85473&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	00C	3FII	25701	136351573	21260				C15521	ZINC04228276	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185720	NC(CS)C(O)=O	InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)	XUJNEKJLAYXESH-UHFFFAOYSA-N	86203	CAS_5862::L-cysteine::NSC_5862	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86203	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86203&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	BTC	1B23,1D7P,1ECX,1GKM,1GL3,1HFE,1I1A,1LI7,1MB4,1N26,1N31,1O7S,1PQU,1R4S,1R51,1RZG,1SSQ,1T3D,1V1Q,1XT8,208L,2D32,2D33,2DF3,2FUB,2G5R,2IBN,2IC1,2ICQ,2IO8,2IX7,2PAD,2V43,2WB9,2YJP,2YLN,2ZSV,3A9Y,3BM5,3C01,3ENJ,3GVD,3P47,3PZR,3Q0E,3TZ6,3V6O,4BB2,4BFE,4BFG,4BFI,4FF9,4G1P,4H7O,4HPC,4IEV,4IEW,4JH8,4JTO,4KSZ,4LMB,4NB0,4NB1,4OTZ,4OWD,4QM8,4QM9,4XF0,4XF1,4XF3,4XFG,4XFH,4YTG,4Z82,4ZU9,5B36,5DB5,5EH1,5EIG,5HCC,5HCD,5HCE,7API,8API,9API	594	136352303	15356				C00736	ZINC00895347	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185721	NC(CS(O)=O)C(O)=O	InChI=1S/C3H7NO4S/c4-2(3(5)6)1-9(7)8/h2H,1,4H2,(H,5,6)(H,7,8)	ADVPTQAUNPRNPO-UHFFFAOYSA-N	86194	CAS_109::L-cysteine sulfinic acid::NSC_109	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86194&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CSD	1EU1,6IKY,6IKT,6Z9O,5NY7,3E9Y,3H4H,6W0U,1TO9,3PHU,3VYH,3VYG,6MTG,4U8E,4Y1R,4Y1F,4G6W,5Z3D,5F8E,5F8F,5F8C,3PSZ,4QYT,1REV,1JKH,3TKK,3TKS,6Z9G,1BQ6,4AGI,6WE7,4NYO,4NYP,3WVD,3WVE,6R6U,4Z37,3FIV,3A8M,7L1P,1XW4,6PT4,3HHT,6Z8M,1FNK,6RUC,1VRU,1Z8N,7LR3,1BI5,4OMR,3H56,3QZ5,3QZ9,2QUG,6FTQ,7Z0V,2Z1D,6DXB,6DXC,6DXA,6DXD,6DX9,7PI0,6MU0,3U7M,3U7L,3U7N,3U7K,5WC4,5B6N,6B4R,1VI9,2ZPB,2ZPG,5K6R,5K6Q,5K6T,5IPG,5FZO,3QOR,7W6G,1SUC,1SUB,1SUD,1Q9U,4AY8,4AY7,7QOY,7QOU,7QOP,7QOM,2FHX,6RTP,3PG8,3QYG,3QYH,4PSS,4PST,4PSY,1TKT,2OPQ,2OPP,2OPS,2OPR,2OPL,2ZZD,7PJN,3I1H,3KI8,1WUO,4OQ4,8ET5,8ET4,2PVZ,1OBF,5V2W,5UR0,4CHL,2C47,5JSH,5JSU,3SMH,2J16,5IMF,5GK0,6RIZ,2R3Q,2R3P,2R3I,2R3K,2R3J,2R3M,2R3L,2R3O,2R3N,5INY,1LW2,1LW0,1LWC,1LWF,1LWE,4IEF,6ISQ,6G4R,5NAI,6N1A,2X1E,3HJ0,4NT8,3WEU,4R0V,4RYB,3QXE,1U9C,4ZGJ,4ZGE,4ZGD,1EKQ,1EKK,1MHW,3X26,3X25,3X24,3X20,3X28,7F87,7F8S,2HL8,3AWJ,3DLE,3DLG,1Q79,1Q78,3C5Y,3A8H,3OQP,3OQI,1DNC,1TKZ,5FQA,2BGA,2BG6,5JT1,1UGR,3SLE,4YUF,2ZCF,5VEX,5VEW,6G5M,5HWR,7AYJ,2IMZ,7U1D,7U1U,4P2G,4EKF,6ZK6,3T8E,4YKG,5NUE,5JQN,3ZJG,3ZJF,2V9S,1OBB,8ADD,6W42,1OKI,7XCF,7W8L,7W8M,4KPH,4U2C,3R66,1JLQ,1JLC,1JLB,1JLE,1JLG,4G2O,7BUR,7BUS,2ETF,7FFA,3P5U,1TL3,1TL1,5IMD,5IMZ,2BFZ,2GCU,6H2U,3L87,6TYY,3BC2,3BC3,3GEF,5SYA,5VF5,2ACT,1DIN,6BKA,1YBH,4LDK,2VYN,2VYV,1YM9,2DD5,1YSL,4OB1,4OB0,4OB3,4OB2,7CTM,1TVZ,1EP4,1UKK,7ZM9,5CPD,1RTH,1RTJ,1RT1,1RT3,1RT2,1RT5,1RT4,1RT7,1RT6,3T6S,1EE0,7STQ,3DMJ,6FXS,1JLA,1JLF,7TZZ,2HNY,2HNZ,2HND,1IRE,3SED,4GE3,5Z89,3EU7,3EUO,3EUT,3EUQ,3MI2,7ARF,3AWK,2E2M,4XLL,1YI1,1YI0,6YG4,4QIB,1TXT,3A9C,2QDY,2D5H,2D51,2D52,2RK6,4WPZ,1V5I,3NRA,7PNK,1VJE,2DPP,7JH0,3UK7,3CWM,3CWL,6UTN,2VB7,5IZD,3DOL,3DOK,2WLX,2WLR,2WL4,4AH4,1I86,3DM2,5IO0,1S1W,1S1V,1S1U,1S1T,1S1X,6VX2,6GW3,3SQZ,5SY9,5WSE,5WSD,5WSF,5H5S,7B1Y,7B1V,4GE0,4WZ0,2OJP,4M5P,5LRY,5LRX,1YHY,4QJE,3A8G,3A8L,3A8O,2D0Q,4WQ8,4WQ9,5G5H,2P0U,7B23,1R7A,1D6I,1D6H,3EA4,5UC5,7QOV,5K2O,5K3S,3H8C,5J78,2X1D,5W3V,1OEU,3SGU,2H9W,6L2D,6L2E,6L2F,5IOW,2C9H,1I88,1I89,5W8Q,6Z7R,3TB2,3LQY,2GDU,7NAY,1SOA,6IL2,6IL0,2RIL,2D3M,3IW3,7A74,7LVC,7UNZ,1W8C,4UAM,3UIO,3UIP,5C7I,4BPY,3CYF,5V5H,1Q1Y,5G5G,1DTT,1DTQ,1VGX,2CYZ,7FBQ,3IL9,4U85,2OAN,1YHZ,1I8B,2AHJ,6Z8J,1ACD,1TKX,1QMV,7T8L,5Y0S,5Y0T,1JWX,4GD7,7KJ0,1FK9,1FKP,1FKO,2G82,6I7R,6I7Q,4FLM,1QFM,2DXB,2DXC,4PIO,1UGP,1OCH,4P5P,4TTG,4RGC,2EG3,2HAI,4PTH,4PTJ,3F5V,2CZ0,2CZ7,2CZ6,4NJ3,1KLM,3EZG,1C1C,1C1B,4V2P,3OP0,4N12,6K5J,2ZPH,2ZPI,2ZPE,2ZPF,6XKH,1QLV,2NQT,1GZ8,6YCB,2D5F,1RTI,2CZ1,7C9J,4I07,4IW7,6ZA1,6C9U,5E68,4ORN,4D52,4Y0N,6B6L,2BC0,2BC2,7MKV,1C0T,1C0U,6ED0,6JFO,1VRT,6QUN,4FM4,6ESZ	109	136352294				4695	C01615	ZINC12501661	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
186863	CC(N)C(=O)c1ccccc1	InChI=1S/C9H11NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7H,10H2,1H3	PUAQLLVFLMYYJJ-UHFFFAOYSA-N	86286	CAS_62258::Cathinone, (-)::NSC_62258	Alpha-2C adrenergic receptor		 765								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86286&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			107786	136352386	59332					ZINC53165482	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
186864	CNC(C)C(O)c1ccccc1	InChI=1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3	KWGRBVOPPLSCSI-UHFFFAOYSA-N	86284	CAS_24221-86-1::CAS_5032::Ephedrine,(+)::Ephedrine,(-)::NSC_5032::Pseudoephedrine, (-)	Alpha-2C adrenergic receptor		 708								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86284&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5032	136352384						ZINC00074840	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
186865	CNC(C)C(=O)c1ccccc1	InChI=1S/C10H13NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,11H,1-2H3	LPLLVINFLBSFRP-UHFFFAOYSA-N	86285	CAS_1576::Methcathinone, (-)::NSC_1576	Alpha-2C adrenergic receptor		 605								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86285&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1576	136352385						ZINC00403055	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
186866	CC(N)C(O)c1ccccc1	InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3	DLNKOYKMWOXYQA-UHFFFAOYSA-N	50022722	(+)2-Amino-1-phenyl-propan-1-ol::(1R, 2R)-2-Amino-1-phenyl-propan-1-ol::(1R, 2S)-2-Amino-1-phenyl-propan-1-ol::(1S, 2R)-2-Amino-1-phenyl-propan-1-ol::(1S, 2S)-2-Amino-1-phenyl-propan-1-ol::2-Amino-1-phenyl-propan-1-ol::Biphetap::Bromanate::Bromatapp::CHEMBL136560::Codamine::Contac::Demazin::Dimetane-DC::Dimetapp::Drize::Hycomine::Norephedrine, (+)::Norephedrine, (-)::Ornade::PHENYLPROPANOLAMINE::Pseudonorephedrine, (+) [cathine, (+)]::Pseudonorephedrine, (-) [cathine, (-)]::Tavist-D::Triaminic-12	Alpha-2C adrenergic receptor		 597								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022722&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	NPU	3U8Q	4786	103933284		CHEMBL136560				ZINC00157548	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
186867	CC(N)C(O)c1ccccc1	InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3	DLNKOYKMWOXYQA-UHFFFAOYSA-N	50022722	(+)2-Amino-1-phenyl-propan-1-ol::(1R, 2R)-2-Amino-1-phenyl-propan-1-ol::(1R, 2S)-2-Amino-1-phenyl-propan-1-ol::(1S, 2R)-2-Amino-1-phenyl-propan-1-ol::(1S, 2S)-2-Amino-1-phenyl-propan-1-ol::2-Amino-1-phenyl-propan-1-ol::Biphetap::Bromanate::Bromatapp::CHEMBL136560::Codamine::Contac::Demazin::Dimetane-DC::Dimetapp::Drize::Hycomine::Norephedrine, (+)::Norephedrine, (-)::Ornade::PHENYLPROPANOLAMINE::Pseudonorephedrine, (+) [cathine, (+)]::Pseudonorephedrine, (-) [cathine, (-)]::Tavist-D::Triaminic-12	Alpha-2C adrenergic receptor		 265								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022722&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	NPU	3U8Q	4786	103933284		CHEMBL136560				ZINC00157548	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
186868	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2C adrenergic receptor		 14.5								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
186869	CNC(C)C(O)c1ccccc1	InChI=1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3	KWGRBVOPPLSCSI-UHFFFAOYSA-N	86284	CAS_24221-86-1::CAS_5032::Ephedrine,(+)::Ephedrine,(-)::NSC_5032::Pseudoephedrine, (-)	Alpha-2C adrenergic receptor		 1220								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86284&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5032	136352384						ZINC00074840	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
186870	CC(N)C(O)c1ccccc1	InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3	DLNKOYKMWOXYQA-UHFFFAOYSA-N	50022722	(+)2-Amino-1-phenyl-propan-1-ol::(1R, 2R)-2-Amino-1-phenyl-propan-1-ol::(1R, 2S)-2-Amino-1-phenyl-propan-1-ol::(1S, 2R)-2-Amino-1-phenyl-propan-1-ol::(1S, 2S)-2-Amino-1-phenyl-propan-1-ol::2-Amino-1-phenyl-propan-1-ol::Biphetap::Bromanate::Bromatapp::CHEMBL136560::Codamine::Contac::Demazin::Dimetane-DC::Dimetapp::Drize::Hycomine::Norephedrine, (+)::Norephedrine, (-)::Ornade::PHENYLPROPANOLAMINE::Pseudonorephedrine, (+) [cathine, (+)]::Pseudonorephedrine, (-) [cathine, (-)]::Tavist-D::Triaminic-12	Alpha-2C adrenergic receptor		 1547								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022722&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	NPU	3U8Q	4786	103933284		CHEMBL136560				ZINC00157548	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
186871	CC(N)C(O)c1ccccc1	InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3	DLNKOYKMWOXYQA-UHFFFAOYSA-N	50022722	(+)2-Amino-1-phenyl-propan-1-ol::(1R, 2R)-2-Amino-1-phenyl-propan-1-ol::(1R, 2S)-2-Amino-1-phenyl-propan-1-ol::(1S, 2R)-2-Amino-1-phenyl-propan-1-ol::(1S, 2S)-2-Amino-1-phenyl-propan-1-ol::2-Amino-1-phenyl-propan-1-ol::Biphetap::Bromanate::Bromatapp::CHEMBL136560::Codamine::Contac::Demazin::Dimetane-DC::Dimetapp::Drize::Hycomine::Norephedrine, (+)::Norephedrine, (-)::Ornade::PHENYLPROPANOLAMINE::Pseudonorephedrine, (+) [cathine, (+)]::Pseudonorephedrine, (-) [cathine, (-)]::Tavist-D::Triaminic-12	Alpha-2C adrenergic receptor		 2804								PDSP Ki	10.1124/jpet.103.053975	10.7270/Q28W3BVJ	12954796			Rothman, RB; Vu, N; Partilla, JS; Roth, BL; Hufeisen, SJ; Compton-Toth, BA; Birkes, J; Young, R; Glennon, RA	National Institute on Drug Abuse	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022722&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	NPU	3U8Q	4786	103933284		CHEMBL136560				ZINC00157548	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185722	NC(CSSCC(N)C(O)=O)C(O)=O	InChI=1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)	LEVWYRKDKASIDU-UHFFFAOYSA-N	86199	CAS_595::CAS_67678::D-cystine::L-cystine::NSC_595::NSC_67678	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86199&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	IYY	8DKM,7ZKW	595	136352299	17376				C01420	ZINC01532673	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185723	N[C@@H](CCS(O)(=O)=O)C(O)=O	InChI=1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m0/s1	VBOQYPQEPHKASR-VKHMYHEASA-N	50220147	(S)-2-amino-4-sulfobutanoic acid::CHEMBL230951::L-2-amino-4-sulfobutyric acid::L-Homocysteate::L-homocysteic acid	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50220147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50220147&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	HJT	6Q6J	177491	104093189		CHEMBL230951			C16511	ZINC02567965	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185724	N[C@@H](CCS(O)=O)C(O)=O	InChI=1S/C4H9NO4S/c5-3(4(6)7)1-2-10(8)9/h3H,1-2,5H2,(H,6,7)(H,8,9)/t3-/m0/s1	PDNJLMZEGXHSCU-VKHMYHEASA-N	86201	L-homocysteine sulfinic acid	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86201	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86201&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			75896	136352301					C01615	ZINC12953438	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185725	N[C@H]1CCSC1=O	InChI=1S/C4H7NOS/c5-3-1-2-7-4(3)6/h3H,1-2,5H2/t3-/m0/s1	KIWQWJKWBHZMDT-VKHMYHEASA-N	86198	CAS_134505::L-homocysteine thiolactone::NSC_134505	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86198&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			134505	136352298	60315					ZINC54009855	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
185726	CSCCC(N)C(O)=O	InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)	FFEARJCKVFRZRR-UHFFFAOYSA-N	86195	CAS_6137::CAS_84815::D-methionine::L-methionine::NSC_6137::NSC_84815	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.047092	10.7270/Q2VT1QN7	12649361			Shi, Q; Savage, JE; Hufeisen, SJ; Rauser, L; Grajkowska, E; Ernsberger, P; Wroblewski, JT; Nadeau, JH; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86195&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	MED	4GLS,4GLU,1Y9Q,1ZUE,5CGO,5CGN,1TKJ,6CNU,3TRY,7P5R,6DZX,3GP4,3TRV,8F16,6WI3,6JV7,4OIJ,4OIK,6PHQ,6PHN,6PHM,1KQ0,5I5A,5I5B,6WKB,2Q33,7UO8,5HHD,5XPK,3TJW,5I1P,5I1S,5I1O,5I1N	876	136352295	16811				C01733	ZINC01532766	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184547	CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31	InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	VMWNQDUVQKEIOC-CYBMUJFWSA-N	50001955	(-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53	Alpha-2C adrenergic receptor		 36.31								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	OR9	7JVQ	6005	103916308	48538	CHEMBL53	DB00714	33		ZINC00009073	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184548	CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C	InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1	OZVBMTJYIDMWIL-AYFBDAFISA-N	81993	BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-)	Alpha-2C adrenergic receptor		 28.18								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	08Y	6VMS,3UA1,7JVR,5VCG	31101	131342567			DB01200		C06856	ZINC53683151	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184549	CCNC(=O)N(CCCN(C)C)C(=O)C1CC2C(Cc3c[nH]c4cccc2c34)N(CC=C)C1	InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)	KORNTPPJEAJQIU-UHFFFAOYSA-N	86052	CAS_54746::Cabergoline::NSC_54746	Alpha-2C adrenergic receptor		 22.39								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86052&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2512	136352152							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184550	CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13	InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1	YEHCICAEULNIGD-MZMPZRCHSA-N	50028421	9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline; compound with methanesulfonic acid::CHEMBL1275::LY-127809::PERGOLIDE MESYLATE::Pergolide::Permax	Alpha-2C adrenergic receptor		 67.61								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028421&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			47811	103937709	8021	CHEMBL1275	DB01186		C07425	ZINC03786466	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184551	C(N1CCN(CC1)c1ncccn1)c1ccc2OCOc2c1	InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2	OQDPVLVUJFGPGQ-UHFFFAOYSA-N	85092	CAS_3605-01-4::NSC_4850::Piribedil	Alpha-2C adrenergic receptor		 69.18								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85092	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85092&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4850	136351192						ZINC19537374	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184552	CCCNC1CCc2nc(N)sc2C1	InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)	FASDKYOPVNHBLU-UHFFFAOYSA-N	50017550	CHEMBL76399::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine (Pramipexole, PPX)::Pramipexole	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017550&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	G6L	7CMU	4885	103928818		CHEMBL76399				ZINC03831352	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184553	CCCN1CCC[C@@H]2Cc3nc(N)ncc3C[C@@H]12	InChI=1S/C14H22N4/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12/h9-10,13H,2-8H2,1H3,(H2,15,16,17)/t10-,13-/m1/s1	TUFADSGTJUOBEH-ZWNOBZJWSA-N	50016017	(5aR,9aR)-6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine::(5aR,9aR)-6-propyl-5,5a,6,7,8,9,9a,10-octahydropyrido[2,3-g]quinazolin-2-amine::6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine(Quinelorane)::CHEMBL155731::Quinelorane::Quinerolane	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016017&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57242	103927698		CHEMBL155731		954		ZINC00005041	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184554	CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12	InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1	FTSUPYGMFAPCFZ-ZWNOBZJWSA-N	84637	CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54562	136350737		CHEMBL240773				ZINC25724686	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184555	CCCN(CCC)CCc1cccc2NC(=O)Cc12	InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19)	UHSKFQJFRQCDBE-UHFFFAOYSA-N	50020680	4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE	Alpha-2C adrenergic receptor		 1202.26								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5095	103931441	8888	CHEMBL589	DB00268	7295	C07564	ZINC00002041	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184556	Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1	InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2	HGEYJZMMUGWEOT-UHFFFAOYSA-N	50002173	3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol::CHEMBL431367::roxindole	Alpha-2C adrenergic receptor		 1.78								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002173&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			219050	103916479	48558	CHEMBL431367		52		ZINC01548439	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184557	Nc1nc2CCN(CC=C)CCc2s1	InChI=1S/C10H15N3S/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8/h2H,1,3-7H2,(H2,11,12)	DHSSDEDRBUKTQY-UHFFFAOYSA-N	86053	B-HT 920::CAS_101626-70-4::CHEMBL279085::NSC_104870::Talipexole::cid_5374	Alpha-2C adrenergic receptor		 42.66								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86053&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5374	136352153		CHEMBL279085				ZINC00006644	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184558	CCN(CC)C(=O)N[C@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1	InChI=1S/C20H28N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,11,14,16,18,21H,4-5,9-10,12H2,1-3H3,(H,22,25)/t14-,16+,18+/m0/s1	JOAHPSVPXZTVEP-YXJHDRRASA-N	50017519	1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-urea::CHEMBL73151::Terguride	Alpha-2C adrenergic receptor		 0.76								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017519&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			443951	103928787		CHEMBL73151				ZINC03811327	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
184559	C[NH+](C)C1CCc2cc(O)c(O)cc2C1	InChI=1S/C12H17NO2/c1-13(2)10-4-3-8-6-11(14)12(15)7-9(8)5-10/h6-7,10,14-15H,3-5H2,1-2H3/p+1	JWLJBTDXCBIGBW-UHFFFAOYSA-O	50025206	(6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dimethyl-ammonium::TL99	Alpha-2C adrenergic receptor		 6.03								PDSP Ki	10.1124/jpet.102.039867	10.7270/Q2MG7N2F	12388666			Millan, MJ; Maiofiss, L; Cussac, D; Audinot, V; Boutin, JA; Newman-Tancredi, A	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025206	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025206&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44299913	103935110						ZINC05965207	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
187657	CCCN(CCC)CCc1cccc2NC(=O)Cc12	InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19)	UHSKFQJFRQCDBE-UHFFFAOYSA-N	50020680	4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE	Alpha-2C adrenergic receptor		 1202.26								PDSP Ki	10.1124/jpet.103.062398	10.7270/Q29S1PM2	14978194			Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5095	103931441	8888	CHEMBL589	DB00268	7295	C07564	ZINC00002041	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
187658	CCCN1CCOC2C1CCc1ccc(cc21)C(N)=O	InChI=1S/C16H22N2O2/c1-2-7-18-8-9-20-15-13-10-12(16(17)19)4-3-11(13)5-6-14(15)18/h3-4,10,14-15H,2,5-9H2,1H3,(H2,17,19)	XKTRZPQOQOCNJU-UHFFFAOYSA-N	86475	S32504	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1124/jpet.103.062398	10.7270/Q29S1PM2	14978194			Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL	Institut de Recherches Servier	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86475&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9925530	136352524						ZINC34031100	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
189042	COc1cccc(C(O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC	InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3	HXTGXYRHXAGCFP-UHFFFAOYSA-N	50232153	(1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethoxyphenyl)methanol::(2,3-Dimethoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::CHEMBL257283::MDL 100907::MDL-100907	Alpha-2C adrenergic receptor		 1442								PDSP Ki	10.1038/sj.npp.1300819	10.7270/Q2KW5DMS	15999145			Pehek, EA; Nocjar, C; Roth, BL; Byrd, TA; Mabrouk, OS	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50232153	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50232153&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60858	104055427		CHEMBL257283				ZINC01851117	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
189043	OC(C1CCN(CCc2ccccc2)CC1)c1ccccc1	InChI=1S/C20H25NO/c22-20(18-9-5-2-6-10-18)19-12-15-21(16-13-19)14-11-17-7-3-1-4-8-17/h1-10,19-20,22H,11-16H2	AXNGJCOYCMDPQG-UHFFFAOYSA-N	50004327	(1-Phenethyl-piperidin-4-yl)-phenyl-methanol::CHEMBL18972::Glemanserin::MDL 11,939::MDL-11939	Alpha-2C adrenergic receptor		 1186								PDSP Ki	10.1038/sj.npp.1300819	10.7270/Q2KW5DMS	15999145			Pehek, EA; Nocjar, C; Roth, BL; Byrd, TA; Mabrouk, OS	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004327	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004327&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71781	103918010		CHEMBL18972				ZINC01843091	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
189044	CN(C)CCON=C(C=Cc1ccc(O)cc1)c1ccccc1F	InChI=1S/C19H21FN2O2/c1-22(2)13-14-24-21-19(17-5-3-4-6-18(17)20)12-9-15-7-10-16(23)11-8-15/h3-12,23H,13-14H2,1-2H3	VAIOZOCLKVMIMN-UHFFFAOYSA-N	81780	CAS_6438382::NSC_6438382::SR 46349B	Alpha-2C adrenergic receptor		 2118								PDSP Ki	10.1038/sj.npp.1300819	10.7270/Q2KW5DMS	15999145			Pehek, EA; Nocjar, C; Roth, BL; Byrd, TA; Mabrouk, OS	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81780&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5486684	131342354						ZINC14953472	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
190327	CCN1CCCC1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC	InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)	NTJOBXMMWNYJFB-UHFFFAOYSA-N	81790	Amisulpride::CAS_71675-85-9::NSC_2159::US10167256, Amisulpride::US10259786, Amisulpride	Alpha-2C adrenergic receptor		 1540								PDSP Ki	10.1007/s00213-009-1521-8	10.7270/Q2TB15G7	19337725			Abbas, AI; Hedlund, PB; Huang, XP; Tran, TB; Meltzer, HY; Roth, BL	Case Western Reserve University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81790	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81790&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2159	131342364	64045		DB06288	963		ZINC01846088	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
187981	CCc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1	InChI=1S/C23H23BrCl2N4O/c1-2-18-21(23(31)28-29-12-4-3-5-13-29)27-30(20-11-10-17(25)14-19(20)26)22(18)15-6-8-16(24)9-7-15/h6-11,14H,2-5,12-13H2,1H3,(H,28,31)	HMXDWDSNPRNUKI-UHFFFAOYSA-N	50171290	5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide::CHEMBL189676::SR 147778	Alpha-2C adrenergic receptor		 1000								PDSP Ki	10.1124/jpet.104.067884	10.7270/Q2RR1WTX	15131245			Rinaldi-Carmona, M; Barth, F; Congy, C; Martinez, S; Oustric, D; P&eacute;rio, A; Poncelet, M; Maruani, J; Arnone, M; Finance, O; Soubri&eacute;, P; Le Fur, G	Sanofi-Synthelabo Recherche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171290&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9849616	104057543		CHEMBL189676				ZINC01549068	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
189339	NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1	InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)	ROFVXGGUISEHAM-UHFFFAOYSA-N	26739	3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate::CHEMBL184238::URB 597::URB-597::URB597::US9187413, 1a (URB597)	Alpha-2C adrenergic receptor		>10000								PDSP Ki	10.1073/pnas.0509591102	10.7270/Q2F47MQJ	16352709			Gobbi, G; Bambico, FR; Mangieri, R; Bortolato, M; Campolongo, P; Solinas, M; Cassano, T; Morgese, MG; Debonnel, G; Duranti, A; Tontini, A; Tarzia, G; Mor, M; Trezza, V; Goldberg, SR; Cuomo, V; Piomelli, D	McGill University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26739&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1383884	57298451		CHEMBL184238		4339		ZINC01238258	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
189569	COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1	InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3	SBPRIAGPYFYCRT-UHFFFAOYSA-N	86708	CAS_146714-97-8::CHEMBL31354::CHEMBL514874::CHEMBL537403::NSC_104911::WAY 100,635	Alpha-2C adrenergic receptor		 2573								PDSP Ki	10.1007/s00213-006-0490-4	10.7270/Q2HX1B8P	16915381			Chemel, BR; Roth, BL; Armbruster, B; Watts, VJ; Nichols, DE	Purdue University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86708&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5684	136352757		CHEMBL537403CHEMBL514874CHEMBL31354				ZINC52541473	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50021048	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JWYUBODPEUBFLH-FSTMKDAKSA-N	50131346	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91157	Alpha-2C adrenergic receptor		 1.4								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131346&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324800	104022530		CHEMBL91157				ZINC22930620	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50238996	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	WZOMJNATDSYQHS-ZPWQMVEJSA-N	50131359	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328114	Alpha-2C adrenergic receptor		 0.500								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131359&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324765	104022543		CHEMBL328114					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239040	COc1cc2OC[C@H]3[C@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-11-9-30(10-12-31)16-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27H,9-12,16-18H2,1-2H3/t23-,27-/m0/s1	XHLHZPFSBCZVEA-HOFKKMOUSA-N	50131351	(3R,3aS)-7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL92860	Alpha-2C adrenergic receptor		 9.5								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131351&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324737	104022535		CHEMBL92860				ZINC22445308	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50590420	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	YMYZKGIHGMHZDL-WDAWEKNVSA-N	50131347	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419316	Alpha-2C adrenergic receptor		 10								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131347&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324972	104022531		CHEMBL419316				ZINC22930623	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
445399	Cc1ccc2N=C(N3CCN(CC(C)(C)C(O)=O)CC3)c3cc(Cl)sc3Oc2c1	InChI=1S/C21H24ClN3O3S/c1-13-4-5-15-16(10-13)28-19-14(11-17(22)29-19)18(23-15)25-8-6-24(7-9-25)12-21(2,3)20(26)27/h4-5,10-11H,6-9,12H2,1-3H3,(H,26,27)	PSYAJOBNPBYKRW-UHFFFAOYSA-N	255474	US9481688, 1::US9481688, 3	Alpha-2C adrenergic receptor		>4230								US Patent		10.7270/Q25D8QRW		aid1803573	US9481688	Ledgard, AJ	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=255474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=255474&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71212556	347830110							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50021039	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JWYUBODPEUBFLH-FSTMKDAKSA-N	50131346	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91157	Alpha-2C adrenergic receptor		 1.40								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131346&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324800	104022530		CHEMBL91157				ZINC22930620	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50021047	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	WZOMJNATDSYQHS-ZPWQMVEJSA-N	50131359	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328114	Alpha-2C adrenergic receptor		 0.500000								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131359&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324765	104022543		CHEMBL328114					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50021060	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	YMYZKGIHGMHZDL-WDAWEKNVSA-N	50131347	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419316	Alpha-2C adrenergic receptor		 10.00								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131347&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324972	104022531		CHEMBL419316				ZINC22930623	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50027494	C[C@@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	NMSAVNXFCXMJJY-GFCCVEGCSA-N	50218115	(R)-2-[1-(3'-nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL242693	Alpha-2C adrenergic receptor					 10.0					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218115&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757089	104091931		CHEMBL242693				ZINC13585593	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50028709	C[C@@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	NMSAVNXFCXMJJY-GFCCVEGCSA-N	50218115	(R)-2-[1-(3'-nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL242693	Alpha-2C adrenergic receptor		 363								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218115&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757089	104091931		CHEMBL242693				ZINC13585593	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50039003	COC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H40N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-15-17-30(18-16-27)40(43)44)34(41)37-21-10-22-39-23-19-36(20-24-39,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,32-33H,10,19-24H2,1-3H3,(H,37,41)	PQRXHDGVJRPPSF-UHFFFAOYSA-N	50366618	CHEMBL448620::SNAP-5089	Alpha-2C adrenergic receptor		 460								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366618&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54203251	160845720		CHEMBL448620				ZINC28759802	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50040307	COC(=O)C1=C(C)NC(C)=C([C@H]1c1cccc(c1)[N+]([O-])=O)C(=O)OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H39N3O6/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24,33,37H,11,18-23H2,1-3H3/t33-/m0/s1	SVJMLYUFVDMUHP-XIFFEERXSA-N	50453799	Niguldipine	Alpha-2C adrenergic receptor		 370								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453799	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453799&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60602	225146125					C11236		1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50046578	Cc1c(Nc2ncc[nH]2)ccc2OCCOc12	InChI=1S/C12H13N3O2/c1-8-9(15-12-13-4-5-14-12)2-3-10-11(8)17-7-6-16-10/h2-5H,6-7H2,1H3,(H2,13,14,15)	NDFYRGCPDAFQDG-UHFFFAOYSA-N	50055832	(1H-Imidazol-2-yl)-(5-methyl-2,3-dihydro-benzo[1,4]dioxin-6-yl)-amine::CHEMBL308570	Alpha-2C adrenergic receptor					 6.6					ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055832&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10176999	103952313		CHEMBL308570				ZINC00020286	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50046582	COc1c(C)c(Nc2ncc[nH]2)c(C)cc1C(C)(C)C	InChI=1S/C16H23N3O/c1-10-9-12(16(3,4)5)14(20-6)11(2)13(10)19-15-17-7-8-18-15/h7-9H,1-6H3,(H2,17,18,19)	AZADEQYOIWOMER-UHFFFAOYSA-N	50055835	(4-tert-Butyl-3-methoxy-2,6-dimethyl-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL75257	Alpha-2C adrenergic receptor					>5000					ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055835&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9795515	103952316		CHEMBL75257				ZINC13760749	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50046592	Brc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	XYLJNLCSTIOKRM-UHFFFAOYSA-N	34572	BRIMONIDINE::CHEMBL844::MLS000069370::SMR000058355::UK 14,304::cid_2435	Alpha-2C adrenergic receptor					 3.4					ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34572&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J59	7EJ8	2435	252617225	3175	CHEMBL844	DB00484	520	C07886	ZINC21303210	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50046593	Cc1c(Nc2ncc[nH]2)ccc2OCCNc12	InChI=1S/C12H14N4O/c1-8-9(16-12-14-4-5-15-12)2-3-10-11(8)13-6-7-17-10/h2-5,13H,6-7H2,1H3,(H2,14,15,16)	JDFLCCTUDMVCCS-UHFFFAOYSA-N	50055830	(1H-Imidazol-2-yl)-(5-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-amine::CHEMBL432155	Alpha-2C adrenergic receptor					 110					ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055830&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9859437	103952311		CHEMBL432155				ZINC00020288	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50050098	CN1CCc2c(Cl)ccc(OCC=C(C)C)c2CC1	InChI=1S/C16H22ClNO/c1-12(2)8-11-19-16-5-4-15(17)13-6-9-18(3)10-7-14(13)16/h4-5,8H,6-7,9-11H2,1-3H3	MBYSTKNEMJZSIK-UHFFFAOYSA-N	50030623	6-Chloro-3-methyl-9-(3-methyl-but-2-enyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL114166::SK&F-104078::SK-104078::SKF 104078	Alpha-2C adrenergic receptor		 64								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030623&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122295	103939472		CHEMBL114166				ZINC05158824	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50050139	COc1ccccc1N1CCN(CCCNc2c(C)c(=O)n(C)c(=O)n2C)CC1	InChI=1S/C21H31N5O3/c1-16-19(23(2)21(28)24(3)20(16)27)22-10-7-11-25-12-14-26(15-13-25)17-8-5-6-9-18(17)29-4/h5-6,8-9,22H,7,10-15H2,1-4H3	HIHZDNKKIUQQSC-UHFFFAOYSA-N	50033112	6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propylamino}-1,3,5-trimethyl-1H-pyrimidine-2,4-dione::CHEMBL420060::Urapidil-5-methyl	Alpha-2C adrenergic receptor		 131								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033112&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5640	103941453		CHEMBL420060		489		ZINC02012436	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50050181	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1COc2ccccc2O1	InChI=1S/C23H25N5O5/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26)	RUZYUOTYCVRMRZ-UHFFFAOYSA-N	86731	CAS_74191-85-8::Doxazosin::UK 33,274	Alpha-2C adrenergic receptor		 280								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86731&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3157	136352780			DB00590		C06970	ZINC00896512	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50050183	COc1cccc(OC)c1OCCNCC1COc2ccccc2O1	InChI=1S/C19H23NO5/c1-21-17-8-5-9-18(22-2)19(17)23-11-10-20-12-14-13-24-15-6-3-4-7-16(15)25-14/h3-9,14,20H,10-13H2,1-2H3	GYSZUJHYXCZAKI-UHFFFAOYSA-N	69602	2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride::CHEMBL25554::MLS000859914::N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride::SMR000326775::WB-4101::WB-4101 hydrochloride::cid_11957505	Alpha-2C adrenergic receptor		 0.8								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69602&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5685	252647768	64094	CHEMBL25554				ZINC02169424	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50050216	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2C adrenergic receptor		 8.4								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50050225	O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c1ccccc1	InChI=1S/C22H25N3O/c26-22(17-6-2-1-3-7-17)24-19-11-14-25(15-12-19)13-10-18-16-23-21-9-5-4-8-20(18)21/h1-9,16,19,23H,10-15H2,(H,24,26)	JXZZEXZZKAWDSP-UHFFFAOYSA-N	50033113	CHEMBL279516::INDORAMIN::INDORAMINE::INDORAMINN-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide::N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide::N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide (Indoramin)::N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide(indoramin)	Alpha-2C adrenergic receptor		 476.0								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033113&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			33625	103941454		CHEMBL279516		501		ZINC00001567	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50050236	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1	InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)	VCKUSRYTPJJLNI-UHFFFAOYSA-N	50033111	1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine::6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine::CHEMBL611::TERAZOSIN::Terazosine	Alpha-2C adrenergic receptor		 213								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033111&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TZN	4O3F,4O33	5401	103941452	9445	CHEMBL611	DB01162	7302	C07127	ZINC01271441	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50050237	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2C adrenergic receptor		 95								ChEMBL	10.1021/jm00018a001	10.7270/Q20G3J6W	7658428			Hieble, JP; Bondinell, WE; Ruffolo, RR	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069408	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2C adrenergic receptor					 794					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069409	CC(Oc1ccccc1-c1cccc(F)c1)C1=NCCN1	InChI=1S/C17H17FN2O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10H2,1H3,(H,19,20)	OOYTZYZXCMCMSZ-UHFFFAOYSA-N	50002903	CHEMBL223836	Alpha-2C adrenergic receptor					 60					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002903&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11211035	242056299		CHEMBL223836					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069410	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2C adrenergic receptor					 58					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069412	CC(Oc1ccccc1-c1cccnc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	AFWQDDUMQAQVSC-UHFFFAOYSA-N	50002905	CHEMBL373535	Alpha-2C adrenergic receptor		 65								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002905&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11265631	242056301		CHEMBL373535					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069414	C[C@@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	NMSAVNXFCXMJJY-GFCCVEGCSA-N	50218115	(R)-2-[1-(3'-nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL242693	Alpha-2C adrenergic receptor		 257								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218115&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757089	104091931		CHEMBL242693				ZINC13585593	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069415	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2C adrenergic receptor		 200								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069420	C[C@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m0/s1	NMSAVNXFCXMJJY-LBPRGKRZSA-N	50417341	CHEMBL397753	Alpha-2C adrenergic receptor		 537								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417341&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757182	163366365		CHEMBL397753				ZINC13585595	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069426	CC(Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)	NMSAVNXFCXMJJY-UHFFFAOYSA-N	50002904	CHEMBL222928	Alpha-2C adrenergic receptor		 234								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002904	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002904&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11361608	242056300		CHEMBL222928					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069433	C[C@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m0/s1	NMSAVNXFCXMJJY-LBPRGKRZSA-N	50417341	CHEMBL397753	Alpha-2C adrenergic receptor					 741					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417341&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757182	163366365		CHEMBL397753				ZINC13585595	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069440	C[C@H](c1cnc[nH]1)c1cccc(C)c1C	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m0/s1	CUHVIMMYOGQXCV-NSHDSACASA-N	50085683	(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole::4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole::CHEMBL778::DEXMEDETOMIDINE::MPV 1440	Alpha-2C adrenergic receptor		 31								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085683&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5311068	103985093	48552	CHEMBL778				ZINC04632106	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069444	C[C@@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m1/s1	OGOLMGZJNRNULQ-CYBMUJFWSA-N	50417353	CHEMBL242265	Alpha-2C adrenergic receptor		 977								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417353&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11043720	163366377		CHEMBL242265				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069446	C[C@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m0/s1	OGOLMGZJNRNULQ-ZDUSSCGKSA-N	50417354	CHEMBL396013	Alpha-2C adrenergic receptor		 302								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417354&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10333157	163366378		CHEMBL396013				ZINC00009140	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069448	C[C@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m0/s1	OGOLMGZJNRNULQ-ZDUSSCGKSA-N	50417354	CHEMBL396013	Alpha-2C adrenergic receptor					 19					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417354&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10333157	163366378		CHEMBL396013				ZINC00009140	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069452	C[C@@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m1/s1	OGOLMGZJNRNULQ-CYBMUJFWSA-N	50417353	CHEMBL242265	Alpha-2C adrenergic receptor					 112					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417353&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11043720	163366377		CHEMBL242265				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069454	CC(Oc1ccccc1-c1cccc(F)c1)C1=NCCN1	InChI=1S/C17H17FN2O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10H2,1H3,(H,19,20)	OOYTZYZXCMCMSZ-UHFFFAOYSA-N	50002903	CHEMBL223836	Alpha-2C adrenergic receptor		 17								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002903&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11211035	242056299		CHEMBL223836					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069463	CC(Oc1ccccc1-c1cccnc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	AFWQDDUMQAQVSC-UHFFFAOYSA-N	50002905	CHEMBL373535	Alpha-2C adrenergic receptor					 50					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002905&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11265631	242056301		CHEMBL373535					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069488	CC(Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)	NMSAVNXFCXMJJY-UHFFFAOYSA-N	50002904	CHEMBL222928	Alpha-2C adrenergic receptor					 100					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002904	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002904&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11361608	242056300		CHEMBL222928					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069497	CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)	XGMNRALXOWECNG-UHFFFAOYSA-N	50417350	CHEMBL374584	Alpha-2C adrenergic receptor					 47					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417350&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11346584	163366374		CHEMBL374584				ZINC13585584	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50069501	CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)	XGMNRALXOWECNG-UHFFFAOYSA-N	50417350	CHEMBL374584	Alpha-2C adrenergic receptor		 18								ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417350&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11346584	163366374		CHEMBL374584				ZINC13585584	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50072069	Fc1cccc(CCNC23OC4C5C6C(C25)C2CC6C4C32)c1	InChI=1S/C19H20FNO/c20-9-3-1-2-8(6-9)4-5-21-19-16-11-7-10-12-13(11)17(19)15(12)18(22-19)14(10)16/h1-3,6,10-18,21H,4-5,7H2	CWYDYWFZPBTTIM-UHFFFAOYSA-N	50305341	8-(3'-Fluorophenethyl)amino-4-oxapentacyclo[5.4.1.02,6.03,10.05,9.08,11]dodecane::CHEMBL590615	Alpha-2C adrenergic receptor		 20								ChEMBL	10.1016/j.bmcl.2009.11.019	10.7270/Q2NS0V0S	19954972			Banister, SD; Moussa, IA; Jordan, MJ; Coster, MJ; Kassiou, M	University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305341&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46225029	104159702		CHEMBL590615					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077512	CCC[C@H]1[C@@H]2c3ccccc3C[C@]12c1cnc[nH]1	InChI=1S/C16H18N2/c1-2-5-13-15-12-7-4-3-6-11(12)8-16(13,15)14-9-17-10-18-14/h3-4,6-7,9-10,13,15H,2,5,8H2,1H3,(H,17,18)/t13-,15-,16+/m0/s1	PRXCUMHAHRIDJF-CWRNSKLLSA-N	50417009	CHEMBL1255724	Alpha-2C adrenergic receptor		 0.436516								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417009	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417009&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52948958	163366033		CHEMBL1255724				ZINC38327733	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077514	CC[C@H]1[C@@H]2c3ccccc3C[C@]12c1cnc[nH]1	InChI=1S/C15H16N2/c1-2-12-14-11-6-4-3-5-10(11)7-15(12,14)13-8-16-9-17-13/h3-6,8-9,12,14H,2,7H2,1H3,(H,16,17)/t12-,14-,15+/m0/s1	ARHWJJBPLJIHQP-AEGPPILISA-N	50417010	CHEMBL1255723	Alpha-2C adrenergic receptor		 0.169824								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417010	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417010&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52944548	163366034		CHEMBL1255723				ZINC64540975	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077525	C[C@H]1[C@@H]2c3ccccc3C[C@]12c1cnc[nH]1	InChI=1S/C14H14N2/c1-9-13-11-5-3-2-4-10(11)6-14(9,13)12-7-15-8-16-12/h2-5,7-9,13H,6H2,1H3,(H,15,16)/t9-,13+,14+/m0/s1	WYFCRYMMLDTJAM-CUOATXAZSA-N	50417019	CHEMBL1256378	Alpha-2C adrenergic receptor		 0.295121								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417019&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52941512	163366043		CHEMBL1256378				ZINC34484999	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077536	CCO[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C15H16N2O/c1-2-18-14-11-6-4-3-5-10(11)12-7-15(12,14)13-8-16-9-17-13/h3-6,8-9,12,14H,2,7H2,1H3,(H,16,17)/t12-,14+,15-/m1/s1	ASHFKBMVCDTQQO-VHDGCEQUSA-N	50417015	CHEMBL1256565	Alpha-2C adrenergic receptor		 10								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417015	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417015&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781006	163366039		CHEMBL1256565				ZINC64548361	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077546	CCC[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C16H18N2/c1-2-5-13-11-6-3-4-7-12(11)14-8-16(13,14)15-9-17-10-18-15/h3-4,6-7,9-10,13-14H,2,5,8H2,1H3,(H,17,18)/t13-,14+,16+/m0/s1	LQKQCQKZRUYZOI-SQWLQELKSA-N	50417012	CHEMBL1255616	Alpha-2C adrenergic receptor		 1.5								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417012	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417012&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781224	163366036		CHEMBL1255616				ZINC64540316	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077548	CCCO[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C16H18N2O/c1-2-7-19-15-12-6-4-3-5-11(12)13-8-16(13,15)14-9-17-10-18-14/h3-6,9-10,13,15H,2,7-8H2,1H3,(H,17,18)/t13-,15+,16-/m1/s1	IXRPDYSTGHYEBR-VNQPRFMTSA-N	50417021	CHEMBL1256566	Alpha-2C adrenergic receptor		 1.5								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417021&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781007	163366045		CHEMBL1256566				ZINC64548362	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077549	C1CC11c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C15H14N2/c1-2-4-11-10(3-1)12-7-15(12,14(11)5-6-14)13-8-16-9-17-13/h1-4,8-9,12H,5-7H2,(H,16,17)/t12-,15-/m1/s1	FYLKUCQQWYKEOG-IUODEOHRSA-N	50417011	CHEMBL1255617	Alpha-2C adrenergic receptor		 20								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417011	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417011&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781887	163366035		CHEMBL1255617				ZINC33961969	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077551	CO[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C14H14N2O/c1-17-13-10-5-3-2-4-9(10)11-6-14(11,13)12-7-15-8-16-12/h2-5,7-8,11,13H,6H2,1H3,(H,15,16)/t11-,13+,14-/m1/s1	HSSBMQXDKGERBI-KWCYVHTRSA-N	50417016	CHEMBL1256503	Alpha-2C adrenergic receptor		 1.95								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417016	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417016&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781005	163366040		CHEMBL1256503				ZINC64528360	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077559	CC(C)O[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C16H18N2O/c1-10(2)19-15-12-6-4-3-5-11(12)13-7-16(13,15)14-8-17-9-18-14/h3-6,8-10,13,15H,7H2,1-2H3,(H,17,18)/t13-,15+,16-/m1/s1	PNISAWOKGCKONH-VNQPRFMTSA-N	50417014	CHEMBL1256608	Alpha-2C adrenergic receptor		 89								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417014	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417014&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781008	163366038		CHEMBL1256608				ZINC64548331	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077560	C[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C14H14N2/c1-9-10-4-2-3-5-11(10)12-6-14(9,12)13-7-15-8-16-13/h2-5,7-9,12H,6H2,1H3,(H,15,16)/t9-,12+,14+/m0/s1	VDSXZDLUEYFJGH-MRCXROJRSA-N	50417020	CHEMBL1256609	Alpha-2C adrenergic receptor		 0.537032								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417020	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417020&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781222	163366044		CHEMBL1256609				ZINC64548332	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077561	CC[C@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C15H16N2/c1-2-12-10-5-3-4-6-11(10)13-7-15(12,13)14-8-16-9-17-14/h3-6,8-9,12-13H,2,7H2,1H3,(H,16,17)/t12-,13+,15+/m0/s1	AKBJKOBHDJQWMB-GZBFAFLISA-N	50417013	CHEMBL1256610	Alpha-2C adrenergic receptor		 1.3								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417013	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417013&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781223	163366037		CHEMBL1256610				ZINC64548333	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077563	CC1(C)[C@@H]2c3ccccc3C[C@]12c1cnc[nH]1	InChI=1S/C15H16N2/c1-14(2)13-11-6-4-3-5-10(11)7-15(13,14)12-8-16-9-17-12/h3-6,8-9,13H,7H2,1-2H3,(H,16,17)/t13-,15+/m0/s1	JWXMKFUDAOLJCY-DZGCQCFKSA-N	50417018	CHEMBL1255770	Alpha-2C adrenergic receptor		 1.2								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417018&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52950140	163366042		CHEMBL1255770				ZINC64540324	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077564	CO[C@@H]1c2ccccc2[C@H]2C[C@@]12c1cnc[nH]1	InChI=1S/C14H14N2O/c1-17-13-10-5-3-2-4-9(10)11-6-14(11,13)12-7-15-8-16-12/h2-5,7-8,11,13H,6H2,1H3,(H,15,16)/t11-,13-,14-/m1/s1	HSSBMQXDKGERBI-MRVWCRGKSA-N	50417017	CHEMBL1256502	Alpha-2C adrenergic receptor		 66								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417017&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781004	163366041		CHEMBL1256502				ZINC64528359	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077565	CCC1(Cc2ccccc2C1)c1cnc[nH]1	InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)	HSWPZIDYAHLZDD-UHFFFAOYSA-N	81807	ATIPAMEZOLE::CAS_104054-27-5::NSC_71310	Alpha-2C adrenergic receptor		 4.2								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81807&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71310	131342381						ZINC05424171	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077566	C[C@]12C[C@]1(Cc1ccccc21)c1cnc[nH]1	InChI=1S/C14H14N2/c1-13-8-14(13,12-7-15-9-16-12)6-10-4-2-3-5-11(10)13/h2-5,7,9H,6,8H2,1H3,(H,15,16)/t13-,14-/m1/s1	DLWKVBPPVYZEML-ZIAGYGMSSA-N	50417008	CHEMBL1255771	Alpha-2C adrenergic receptor		 2.8								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417008&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52943739	163366032		CHEMBL1255771				ZINC64539747	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077568	CCC1(Cc2ccc(F)cc2C1)c1cnc[nH]1	InChI=1S/C14H15FN2/c1-2-14(13-8-16-9-17-13)6-10-3-4-12(15)5-11(10)7-14/h3-5,8-9H,2,6-7H2,1H3,(H,16,17)	KXSUAWAUCNFBQJ-UHFFFAOYSA-N	50417007	FIPAMEZOLE	Alpha-2C adrenergic receptor		 14								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417007&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			213041	163366031						ZINC05424460	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50077570	C1[C@@H]2c3ccccc3C[C@]12c1cnc[nH]1	InChI=1S/C13H12N2/c1-2-4-10-9(3-1)5-13(6-11(10)13)12-7-14-8-15-12/h1-4,7-8,11H,5-6H2,(H,14,15)/t11-,13+/m1/s1	FIERHAFMRVRMDV-YPMHNXCESA-N	50417006	CHEMBL1256414	Alpha-2C adrenergic receptor		 0.129								ChEMBL	10.1021/jm1006269	10.7270/Q2T154X2	20809632			Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M	Pierre Fabre Research Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417006	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417006&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49781228	163366030		CHEMBL1256414				ZINC64549483	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50087270	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2C adrenergic receptor		 30								ChEMBL	10.1021/jm960359r	10.7270/Q2PC31GF	8784451			Munk, SA; Harcourt, D; Ambrus, G; Denys, L; Gluchowski, C; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50087278	Cc1c(ccc2nccnc12)N=C1NCCN1	InChI=1S/C12H13N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-5H,6-7H2,1H3,(H2,15,16,17)	QZUXRMOPAGPTIY-UHFFFAOYSA-N	50052880	CHEMBL49137::Imidazolidin-2-ylidene-(5-methyl-quinoxalin-6-yl)-amine	Alpha-2C adrenergic receptor		 27								ChEMBL	10.1021/jm960359r	10.7270/Q2PC31GF	8784451			Munk, SA; Harcourt, D; Ambrus, G; Denys, L; Gluchowski, C; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052880&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			185076	103949620		CHEMBL49137				ZINC05159693	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50087285	Cc1c(ccc2NCCNc12)N=C1NCCN1	InChI=1S/C12H17N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-3,13-14H,4-7H2,1H3,(H2,15,16,17)	PGOVKWAJCVAZNG-UHFFFAOYSA-N	50052881	AGN-192172::CHEMBL49284::Imidazolidin-2-ylidene-(5-methyl-1,2,3,4-tetrahydro-quinoxalin-6-yl)-amine	Alpha-2C adrenergic receptor		 120								ChEMBL	10.1021/jm960359r	10.7270/Q2PC31GF	8784451			Munk, SA; Harcourt, D; Ambrus, G; Denys, L; Gluchowski, C; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052881&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9816048	103949621		CHEMBL49284				ZINC13757898	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50087286	Nc1cc(Cl)c(N=C2NCCN2)c(Cl)c1	InChI=1S/C9H10Cl2N4/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2,12H2,(H2,13,14,15)	IEJXVRYNEISIKR-UHFFFAOYSA-N	50021812	2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine::2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine (p-aminoclonidine)::2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine(p-Aminoclonidine)::APRACLONIDINE::CHEMBL647::P-AMINOCLONIDINE2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-diamine	Alpha-2C adrenergic receptor		 30								ChEMBL	10.1021/jm960359r	10.7270/Q2PC31GF	8784451			Munk, SA; Harcourt, D; Ambrus, G; Denys, L; Gluchowski, C; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021812&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2216	103932510	2788	CHEMBL647		7117		ZINC00057175	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50087292	Cc1c(ccc2OCCNc12)N=C1NCCN1	InChI=1S/C12H16N4O/c1-8-9(16-12-14-4-5-15-12)2-3-10-11(8)13-6-7-17-10/h2-3,13H,4-7H2,1H3,(H2,14,15,16)	OSJZLDGTMVBIRV-UHFFFAOYSA-N	50052882	AGN-193080::CHEMBL298936::Imidazolidin-2-ylidene-(5-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-amine	Alpha-2C adrenergic receptor		 8.9								ChEMBL	10.1021/jm960359r	10.7270/Q2PC31GF	8784451			Munk, SA; Harcourt, D; Ambrus, G; Denys, L; Gluchowski, C; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052882	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052882&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9837551	103949622		CHEMBL298936				ZINC00006307	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093095	Cc1c(Nc2ncc[nH]2)ccc2OCCNc12	InChI=1S/C12H14N4O/c1-8-9(16-12-14-4-5-15-12)2-3-10-11(8)13-6-7-17-10/h2-5,13H,6-7H2,1H3,(H2,14,15,16)	JDFLCCTUDMVCCS-UHFFFAOYSA-N	50055830	(1H-Imidazol-2-yl)-(5-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-amine::CHEMBL432155	Alpha-2C adrenergic receptor		 230								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055830&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9859437	103952311		CHEMBL432155				ZINC00020288	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093096	Cc1c(Nc2ncc[nH]2)ccc2nccnc12	InChI=1S/C12H11N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-7H,1H3,(H2,15,16,17)	AEWIKTWIKIWVNJ-UHFFFAOYSA-N	50055829	(1H-Imidazol-2-yl)-(5-methyl-quinoxalin-6-yl)-amine::CHEMBL75491	Alpha-2C adrenergic receptor		 340								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055829&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9794524	103952310		CHEMBL75491				ZINC00020289	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093099	N(c1ncc[nH]1)c1ccc2nc[nH]c2c1	InChI=1S/C10H9N5/c1-2-8-9(14-6-13-8)5-7(1)15-10-11-3-4-12-10/h1-6H,(H,13,14)(H2,11,12,15)	NFSIDEIKDWWMOX-UHFFFAOYSA-N	50055831	(1H-Benzoimidazol-5-yl)-(1H-imidazol-2-yl)-amine::CHEMBL74544	Alpha-2C adrenergic receptor		 400								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055831&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10655607	103952312		CHEMBL74544				ZINC13760751	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093105	Cc1c(ccc2nccnc12)N=C1NCCN1	InChI=1S/C12H13N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-5H,6-7H2,1H3,(H2,15,16,17)	QZUXRMOPAGPTIY-UHFFFAOYSA-N	50052880	CHEMBL49137::Imidazolidin-2-ylidene-(5-methyl-quinoxalin-6-yl)-amine	Alpha-2C adrenergic receptor		 27								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052880&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			185076	103949620		CHEMBL49137				ZINC05159693	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093107	Brc1ccccc1Nc1ncc[nH]1	InChI=1S/C9H8BrN3/c10-7-3-1-2-4-8(7)13-9-11-5-6-12-9/h1-6H,(H2,11,12,13)	KHNAVCNEASQADL-UHFFFAOYSA-N	50055833	(2-Bromo-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL76457	Alpha-2C adrenergic receptor		 2400								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055833&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10490084	103952314		CHEMBL76457				ZINC13760746	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093114	Cc1c(Nc2ncc[nH]2)ccc2OCCOc12	InChI=1S/C12H13N3O2/c1-8-9(15-12-13-4-5-14-12)2-3-10-11(8)17-7-6-16-10/h2-5H,6-7H2,1H3,(H2,13,14,15)	NDFYRGCPDAFQDG-UHFFFAOYSA-N	50055832	(1H-Imidazol-2-yl)-(5-methyl-2,3-dihydro-benzo[1,4]dioxin-6-yl)-amine::CHEMBL308570	Alpha-2C adrenergic receptor		 19								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055832&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10176999	103952313		CHEMBL308570				ZINC00020286	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093123	COc1ccc(Nc2ncc[nH]2)c(C)c1OC	InChI=1S/C12H15N3O2/c1-8-9(15-12-13-6-7-14-12)4-5-10(16-2)11(8)17-3/h4-7H,1-3H3,(H2,13,14,15)	AMBHHYSUKMHFDB-UHFFFAOYSA-N	50055834	(3,4-Dimethoxy-2-methyl-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL308863	Alpha-2C adrenergic receptor		 1500								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055834&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10609673	103952315		CHEMBL308863				ZINC13760748	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093124	Clc1cccc(Cl)c1Nc1ncc[nH]1	InChI=1S/C9H7Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-5H,(H2,12,13,14)	JMIQFISPBOHMQG-UHFFFAOYSA-N	50055836	(2,6-Dichloro-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL1022	Alpha-2C adrenergic receptor		 1100								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055836&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10489502	103952317		CHEMBL1022				ZINC03820959	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093128	COc1c(C)c(Nc2ncc[nH]2)c(C)cc1C(C)(C)C	InChI=1S/C16H23N3O/c1-10-9-12(16(3,4)5)14(20-6)11(2)13(10)19-15-17-7-8-18-15/h7-9H,1-6H3,(H2,17,18,19)	AZADEQYOIWOMER-UHFFFAOYSA-N	50055835	(4-tert-Butyl-3-methoxy-2,6-dimethyl-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL75257	Alpha-2C adrenergic receptor		 88								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055835&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9795515	103952316		CHEMBL75257				ZINC13760749	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093143	COc1ccc(Nc2ncc[nH]2)c(C)c1	InChI=1S/C11H13N3O/c1-8-7-9(15-2)3-4-10(8)14-11-12-5-6-13-11/h3-7H,1-2H3,(H2,12,13,14)	BEAKKNUWBXQLLR-UHFFFAOYSA-N	50055827	(1H-Imidazol-2-yl)-(4-methoxy-2-methyl-phenyl)-amine::CHEMBL77913	Alpha-2C adrenergic receptor		 512.0								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055827&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10198135	103952308		CHEMBL77913				ZINC00020287	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093147	Brc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	XYLJNLCSTIOKRM-UHFFFAOYSA-N	34572	BRIMONIDINE::CHEMBL844::MLS000069370::SMR000058355::UK 14,304::cid_2435	Alpha-2C adrenergic receptor		 44								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34572&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J59	7EJ8	2435	252617225	3175	CHEMBL844	DB00484	520	C07886	ZINC21303210	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093149	COc1cc(C)c(Nc2ncc[nH]2)cc1C(C)(C)C	InChI=1S/C15H21N3O/c1-10-8-13(19-5)11(15(2,3)4)9-12(10)18-14-16-6-7-17-14/h6-9H,1-5H3,(H2,16,17,18)	QELYRGGNEIAOKD-UHFFFAOYSA-N	50055837	(5-tert-Butyl-4-methoxy-2-methyl-phenyl)-(1H-imidazol-2-yl)-amine::CHEMBL78190	Alpha-2C adrenergic receptor		 290								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055837&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10682720	103952318		CHEMBL78190				ZINC13760750	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093152	N(c1ncc[nH]1)c1ccc2nccnc2c1	InChI=1S/C11H9N5/c1-2-9-10(13-4-3-12-9)7-8(1)16-11-14-5-6-15-11/h1-7H,(H2,14,15,16)	CDFWKVORAWOKDO-UHFFFAOYSA-N	50055838	(1H-Imidazol-2-yl)-quinoxalin-6-yl-amine::CHEMBL74449	Alpha-2C adrenergic receptor		 8800								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055838&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10632290	103952319		CHEMBL74449				ZINC13760747	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50093157	Brc1c(Nc2ncc[nH]2)ccc2nccnc12	InChI=1S/C11H8BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-6H,(H2,15,16,17)	FJXZFBTUCZEINA-UHFFFAOYSA-N	50055828	(5-Bromo-quinoxalin-6-yl)-(1H-imidazol-2-yl)-amine::CHEMBL1019	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1021/jm9605142	10.7270/Q2RV0MST	9016324			Munk, SA; Harcourt, DA; Arasasingham, PN; Burke, JA; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Roberts, D; Runde, E; Williams, L; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055828&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10214826	103952309		CHEMBL1019				ZINC13760745	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50092485	CC(C)N(CCNC(=O)c1ccc(CNS(=O)(=O)c2ccc(C)cc2)cc1)Cc1ccccc1	InChI=1S/C27H33N3O3S/c1-21(2)30(20-24-7-5-4-6-8-24)18-17-28-27(31)25-13-11-23(12-14-25)19-29-34(32,33)26-15-9-22(3)10-16-26/h4-16,21,29H,17-20H2,1-3H3,(H,28,31)	JEJWQCTZDAJWOX-UHFFFAOYSA-N	54817	4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-yl-amino]ethyl]benzamide::4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-ylamino]ethyl]benzamide::MLS000682490::N-[2-[benzyl(isopropyl)amino]ethyl]-4-[(tosylamino)methyl]benzamide::N-[2-[benzyl(propan-2-yl)amino]ethyl]-4-[[(4-methylphenyl)sulfonylamino]methyl]benzamide::N-{2-[benzyl(isopropyl)amino]ethyl}-4-({[(4-methylphenyl)sulfonyl]amino}methyl)benzamide::SMR000314971::cid_3342390	Alpha-2C adrenergic receptor		<1000								ChEMBL	10.1016/j.bmcl.2014.03.040	10.7270/Q2222WBX	24690494			Urbano, M; Guerrero, M; Rosen, H; Roberts, E	The Scripps Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54817&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3342390	252634834						ZINC00450971	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50103007	COc1cccc2[C@@H]3CN(CCn4c(=O)[nH]c5c6ncccc6sc5c4=O)C[C@@H]3CCc12	InChI=1S/C24H24N4O3S/c1-31-18-5-2-4-15-16(18)8-7-14-12-27(13-17(14)15)10-11-28-23(29)22-21(26-24(28)30)20-19(32-22)6-3-9-25-20/h2-6,9,14,17H,7-8,10-13H2,1H3,(H,26,30)/t14-,17+/m0/s1	OLPQNRLJYOGSGV-WMLDXEAASA-N	50060965	2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione::2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,6-triaza-fluorene-1,3-dione::2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione::A-131701::CHEMBL40650	Alpha-2C adrenergic receptor		 16.6								ChEMBL	10.1021/jm970364a	10.7270/Q2R78DBB	9379432			Meyer, MD; Altenbach, RJ; Basha, FZ; Carroll, WA; Drizin, I; Elmore, SW; Ehrlich, PP; Lebold, SA; Tietje, K; Sippy, KB; Wendt, MD; Plata, DJ; Plagge, F; Buckner, SA; Brune, ME; Hancock, AA; Kerwin, JF	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060965	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060965&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10527469	103956571		CHEMBL40650				ZINC25422025	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50103011	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1	InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)	VCKUSRYTPJJLNI-UHFFFAOYSA-N	50033111	1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine::6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine::CHEMBL611::TERAZOSIN::Terazosine	Alpha-2C adrenergic receptor		 78								ChEMBL	10.1021/jm970364a	10.7270/Q2R78DBB	9379432			Meyer, MD; Altenbach, RJ; Basha, FZ; Carroll, WA; Drizin, I; Elmore, SW; Ehrlich, PP; Lebold, SA; Tietje, K; Sippy, KB; Wendt, MD; Plata, DJ; Plagge, F; Buckner, SA; Brune, ME; Hancock, AA; Kerwin, JF	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033111&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TZN	4O3F,4O33	5401	103941452	9445	CHEMBL611	DB01162	7302	C07127	ZINC01271441	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50103022	CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(c1)S(N)(=O)=O	InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1	DRHKJLXJIQTDTD-OAHLLOKOSA-N	50060964	(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide::5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide::5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide::CHEMBL836::TAMSULOSIN	Alpha-2C adrenergic receptor		 7.9								ChEMBL	10.1021/jm970364a	10.7270/Q2R78DBB	9379432			Meyer, MD; Altenbach, RJ; Basha, FZ; Carroll, WA; Drizin, I; Elmore, SW; Ehrlich, PP; Lebold, SA; Tietje, K; Sippy, KB; Wendt, MD; Plata, DJ; Plagge, F; Buckner, SA; Brune, ME; Hancock, AA; Kerwin, JF	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060964&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	JGX		129211	103956570	9398	CHEMBL836	DB00706	488	C07124	ZINC01530694	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50102152	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2C adrenergic receptor		 0.500000								ChEMBL	10.1021/jm401895u	10.7270/Q2N29ZHX	24805037			Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P	Adamed Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50102189	COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17+,18+,19+/m1/s1	BLGXFZZNTVWLAY-DIRVCLHFSA-N	50026636	17alpha-hydroxy-20alpha-yohimban-16beta-carboxylic acid methyl ester::CHEMBL10347::RAUWOLSCINE HYDROCHLORIDE::alpha-yohimbine::corynanthidine::isoyohimbine::mesoyohimbine::methyl (16beta,17alpha,20alpha)-17-hydroxyyohimban-16-carboxylate::methyl 17alpha-hydroxy-20alpha-yohimban-16beta-carboxylate::rauwolscine	Alpha-2C adrenergic receptor			 16							ChEMBL	10.1021/jm401895u	10.7270/Q2N29ZHX	24805037			Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P	Adamed Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026636&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			643606	103936228	48565	CHEMBL10347				ZINC03977785	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50102319	Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cc3ccccc3s2)CC1	InChI=1S/C24H26FN3O3S2/c25-19-7-8-20-21(16-19)31-27-24(20)17-9-13-28(14-10-17)12-4-3-11-26-33(29,30)23-15-18-5-1-2-6-22(18)32-23/h1-2,5-8,15-17,26H,3-4,9-14H2	GXZWKZAOGQRNTL-UHFFFAOYSA-N	50018019	CHEMBL3290012	Alpha-2C adrenergic receptor		 1.9								ChEMBL	10.1021/jm401895u	10.7270/Q2N29ZHX	24805037			Kolaczkowski, M; Marcinkowska, M; Bucki, A; Pawlowski, M; Mitka, K; Jaskowska, J; Kowalski, P; Kazek, G; Siwek, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P	Adamed Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018019&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			56944383	103929195		CHEMBL3290012				ZINC28102656	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50101484	C(CN1CCN(CC1)c1ncccn1)Cc1nc2ccccc2s1	InChI=1S/C18H21N5S/c1-2-6-16-15(5-1)21-17(24-16)7-3-10-22-11-13-23(14-12-22)18-19-8-4-9-20-18/h1-2,4-6,8-9H,3,7,10-14H2	PQVQCEDGSJVHMK-UHFFFAOYSA-N	50017964	CHEMBL3289656	Alpha-2C adrenergic receptor		 126								ChEMBL	10.1016/j.bmc.2014.04.026	10.7270/Q25140RW	24800940			Sampson, D; Zhu, XY; Eyunni, SV; Etukala, JR; Ofori, E; Bricker, B; Lamango, NS; Setola, V; Roth, BL; Ablordeppey, SY	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017964&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			56852956	242041856		CHEMBL3289656					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50118767	CNC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(C(=O)OC)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C32H39N5O6/c1-21-26(29(38)33-3)28(23-11-13-25(14-12-23)37(41)42)27(22(2)35-21)30(39)34-17-8-18-36-19-15-32(16-20-36,31(40)43-4)24-9-6-5-7-10-24/h5-7,9-14,26,28H,8,15-20H2,1-4H3,(H,33,38)(H,34,39)	AGNYFINNIVFBHA-UHFFFAOYSA-N	50068818	1-(3-{[2,6-Dimethyl-5-methylcarbamoyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3-carbonyl]-amino}-propyl)-4-phenyl-piperidine-4-carboxylic acid methyl ester::CHEMBL147077	Alpha-2C adrenergic receptor		 2244								ChEMBL	10.1021/jm980506g	10.7270/Q2R78DCS	9857099			Nagarathnam, D; Wetzel, JM; Miao, SW; Marzabadi, MR; Chiu, G; Wong, WC; Hong, X; Fang, J; Forray, C; Branchek, TA; Heydorn, WE; Chang, RS; Broten, T; Schorn, TW; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068818&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53641825	103962996		CHEMBL147077				ZINC27563665	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127390	CC(=O)Oc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C27H31N3O4/c1-19(14-21-6-4-3-5-7-21)16-29-10-12-30(13-11-29)17-26-24-18-32-25-15-22(33-20(2)31)8-9-23(25)27(24)28-34-26/h3-9,14-15,24,26H,10-13,16-18H2,1-2H3/b19-14+/t24-,26-/m0/s1	AYMCTBRVXPCORT-DPAPPHFXSA-N	50163489	Acetic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-ylester::CHEMBL176116	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163489&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11259744	104049489		CHEMBL176116				ZINC22933293	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127399	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(O)ccc32)CC1)=C/c1ccccc1	InChI=1S/C25H29N3O3/c1-18(13-19-5-3-2-4-6-19)15-27-9-11-28(12-10-27)16-24-22-17-30-23-14-20(29)7-8-21(23)25(22)26-31-24/h2-8,13-14,22,24,29H,9-12,15-17H2,1H3/b18-13+/t22-,24-/m0/s1	UCFVOQSSWZQWNE-ZCIIVOIYSA-N	50163468	(3R,3aS)-3-[4-((E)-2-Methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-ol::CHEMBL180470	Alpha-2C adrenergic receptor		 0.100000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163468&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11384600	104049468		CHEMBL180470				ZINC22933289	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127422	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(OC(=O)C4CC4)ccc32)CC1)=C/c1ccccc1	InChI=1S/C29H33N3O4/c1-20(15-21-5-3-2-4-6-21)17-31-11-13-32(14-12-31)18-27-25-19-34-26-16-23(35-29(33)22-7-8-22)9-10-24(26)28(25)30-36-27/h2-6,9-10,15-16,22,25,27H,7-8,11-14,17-19H2,1H3/b20-15+/t25-,27-/m0/s1	COPXFRMTXFPQKE-JZACSLLISA-N	50163483	CHEMBL175911::Cyclopropanecarboxylic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-yl ester	Alpha-2C adrenergic receptor		 0.300000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163483&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11785068	104049483		CHEMBL175911				ZINC22933302	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127456	COc1cc2N(C)C[C@H]3[C@H](CN4CCN(CCC\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C30H40N4O3/c1-22(17-23-10-6-5-7-11-23)9-8-12-33-13-15-34(16-14-33)21-29-25-20-32(2)26-19-28(36-4)27(35-3)18-24(26)30(25)31-37-29/h5-7,10-11,17-19,25,29H,8-9,12-16,20-21H2,1-4H3/b22-17+/t25-,29-/m0/s1	JKWINILVOXJHQG-WTVFRJDWSA-N	50024319	CHEMBL2112977	Alpha-2C adrenergic receptor		 4								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024319&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456238	103934525		CHEMBL2112977				ZINC27851984	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127465	C(\C=C\c1ccccc1)N1CCN(C[C@@H]2ON=C3[C@H]2COc2ccccc32)CC1	InChI=1S/C24H27N3O2/c1-2-7-19(8-3-1)9-6-12-26-13-15-27(16-14-26)17-23-21-18-28-22-11-5-4-10-20(22)24(21)25-29-23/h1-11,21,23H,12-18H2/b9-6+/t21-,23-/m0/s1	MUUSOYWTPTTZII-BASMTRSQSA-N	50024316	CHEMBL2112978	Alpha-2C adrenergic receptor		 1.7								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024316&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71450907	103934522		CHEMBL2112978				ZINC06019738	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127471	C([C@@H]1ON=C2[C@H]1CNc1ccccc21)N1CCN(Cc2ccc3ccccc3c2)CC1	InChI=1S/C26H28N4O/c1-2-6-21-15-19(9-10-20(21)5-1)17-29-11-13-30(14-12-29)18-25-23-16-27-24-8-4-3-7-22(24)26(23)28-31-25/h1-10,15,23,25,27H,11-14,16-18H2/t23-,25-/m0/s1	WUSIUKLVFNJEHL-ZCYQVOJMSA-N	50024303	CHEMBL2112984	Alpha-2C adrenergic receptor		 9.6								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024303	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024303&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71454490	277286503		CHEMBL2112984					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127476	COc1cc2NC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H34N4O3/c1-19(13-20-7-5-4-6-8-20)17-30-9-11-31(12-10-30)18-26-22-16-28-23-15-25(33-3)24(32-2)14-21(23)27(22)29-34-26/h4-8,13-15,22,26,28H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JODRRUQCPGURFJ-FSTMKDAKSA-N	50024301	CHEMBL2112985	Alpha-2C adrenergic receptor		 0.100000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024301&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11202065	277286501		CHEMBL2112985					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127480	COc1ccc2C3=NO[C@@H](CN4CCN(C\C=C\c5ccccc5)CC4)[C@@H]3C=Cc2c1	InChI=1S/C26H29N3O2/c1-30-22-10-12-23-21(18-22)9-11-24-25(31-27-26(23)24)19-29-16-14-28(15-17-29)13-5-8-20-6-3-2-4-7-20/h2-12,18,24-25H,13-17,19H2,1H3/b8-5+/t24-,25-/m0/s1	SATXLDNXPGMNQI-AIDJPXSQSA-N	50024305	CHEMBL2112982	Alpha-2C adrenergic receptor		 3.9								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024305&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456240	277286505		CHEMBL2112982					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127481	COc1cc2OC[C@H]3[C@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-11-9-30(10-12-31)16-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27H,9-12,16-18H2,1-2H3/t23-,27-/m0/s1	XHLHZPFSBCZVEA-HOFKKMOUSA-N	50131351	(3R,3aS)-7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL92860	Alpha-2C adrenergic receptor		 0.800000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131351&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324737	104022535		CHEMBL92860				ZINC22445308	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127483	COc1cc2NC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H32N4O3/c1-31-23-15-20-22(16-24(23)32-2)27-17-21-25(33-28-26(20)21)18-30-13-11-29(12-14-30)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25,27H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	XWFFXPGAYIJUAN-ZPWQMVEJSA-N	50024302	CHEMBL2112983	Alpha-2C adrenergic receptor		 5.4								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024302	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024302&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11224687	277286502		CHEMBL2112983					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127486	COc1cc2NC[C@H]3[C@H](CN4CCN(Cc5ccc6ncccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C27H31N5O3/c1-33-24-13-20-23(14-25(24)34-2)29-15-21-26(35-30-27(20)21)17-32-10-8-31(9-11-32)16-18-5-6-22-19(12-18)4-3-7-28-22/h3-7,12-14,21,26,29H,8-11,15-17H2,1-2H3/t21-,26-/m0/s1	DDSYDFFJQMGTMM-LVXARBLLSA-N	50024307	CHEMBL2112980	Alpha-2C adrenergic receptor		>1000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024307&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71454489	277286507		CHEMBL2112980					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127489	C(\C=C\c1ccccc1)N1CCN(C[C@@H]2ON=C3[C@H]2CNc2ccccc32)CC1	InChI=1S/C24H28N4O/c1-2-7-19(8-3-1)9-6-12-27-13-15-28(16-14-27)18-23-21-17-25-22-11-5-4-10-20(22)24(21)26-29-23/h1-11,21,23,25H,12-18H2/b9-6+/t21-,23-/m0/s1	HCMWMLSNHRNVSJ-BASMTRSQSA-N	50024304	CHEMBL2112981	Alpha-2C adrenergic receptor		 15								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024304&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11486051	277286504		CHEMBL2112981					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127491	C(\C=C\c1ccccc1)N1CCN(C[C@@H]2ON=C3[C@H]2C=Cc2ccccc32)CC1	InChI=1S/C25H27N3O/c1-2-7-20(8-3-1)9-6-14-27-15-17-28(18-16-27)19-24-23-13-12-21-10-4-5-11-22(21)25(23)26-29-24/h1-13,23-24H,14-19H2/b9-6+/t23-,24-/m0/s1	PKXHLBVPUHXZNH-CWPZKOGPSA-N	50024306	CHEMBL2112979	Alpha-2C adrenergic receptor		 112								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024306&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456239	277286506		CHEMBL2112979					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127498	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	YMYZKGIHGMHZDL-WDAWEKNVSA-N	50131347	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419316	Alpha-2C adrenergic receptor		 0.600000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131347&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324972	104022531		CHEMBL419316				ZINC22930623	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127516	CN(C)CCOc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C29H38N4O3/c1-22(17-23-7-5-4-6-8-23)19-32-11-13-33(14-12-32)20-28-26-21-35-27-18-24(34-16-15-31(2)3)9-10-25(27)29(26)30-36-28/h4-10,17-18,26,28H,11-16,19-21H2,1-3H3/b22-17+/t26-,28-/m0/s1	NCOXQFRYWWZGEM-GRDZPNQDSA-N	50163479	CHEMBL176261::Dimethyl-(2-{(3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-yloxy}-ethyl)-amine	Alpha-2C adrenergic receptor		 0.100000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163479&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11271808	104049479		CHEMBL176261				ZINC22582179	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127520	CCOC(=O)N1C[C@H]2[C@H](CN3CCN(C\C=C\c4ccccc4)CC3)ON=C2c2ccccc12	InChI=1S/C27H32N4O3/c1-2-33-27(32)31-19-23-25(34-28-26(23)22-12-6-7-13-24(22)31)20-30-17-15-29(16-18-30)14-8-11-21-9-4-3-5-10-21/h3-13,23,25H,2,14-20H2,1H3/b11-8+/t23-,25-/m0/s1	CHKGJSUYXRACOM-BSNUYDGMSA-N	50024309	CHEMBL2112975	Alpha-2C adrenergic receptor		 9.8								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024309&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11385652	277286509		CHEMBL2112975					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127523	COc1cc2NC[C@H]3[C@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H32N4O3/c1-33-25-14-22-24(15-26(25)34-2)29-16-23-27(35-30-28(22)23)18-32-11-9-31(10-12-32)17-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27,29H,9-12,16-18H2,1-2H3/t23-,27-/m0/s1	UYRONJVHVBKEPX-HOFKKMOUSA-N	50024318	CHEMBL2112976	Alpha-2C adrenergic receptor		 12								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024318	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024318&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71458044	103934524		CHEMBL2112976				ZINC27766986	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127527	CCNC(=O)N1C[C@H]2[C@H](CN3CCN(C\C=C\c4ccccc4)CC3)ON=C2c2ccccc12	InChI=1S/C27H33N5O2/c1-2-28-27(33)32-19-23-25(34-29-26(23)22-12-6-7-13-24(22)32)20-31-17-15-30(16-18-31)14-8-11-21-9-4-3-5-10-21/h3-13,23,25H,2,14-20H2,1H3,(H,28,33)/b11-8+/t23-,25-/m0/s1	SPMYVDNOOYXROZ-BSNUYDGMSA-N	50024311	CHEMBL2112973	Alpha-2C adrenergic receptor		 2.7								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024311&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11224953	277286511		CHEMBL2112973					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127538	COc1cc2NC[C@H]3[C@H](CN4CCN(Cc5ccc(Cl)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C24H29ClN4O3/c1-30-21-11-18-20(12-22(21)31-2)26-13-19-23(32-27-24(18)19)15-29-9-7-28(8-10-29)14-16-3-5-17(25)6-4-16/h3-6,11-12,19,23,26H,7-10,13-15H2,1-2H3/t19-,23-/m0/s1	DPWMWVBVQVDTJY-CVDCTZTESA-N	50024308	CHEMBL2112974	Alpha-2C adrenergic receptor		 23								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024308&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11385548	277286508		CHEMBL2112974					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127540	COc1cc2NC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H34N4O3/c1-19(20-7-5-4-6-8-20)9-10-30-11-13-31(14-12-30)18-26-22-17-28-23-16-25(33-3)24(32-2)15-21(23)27(22)29-34-26/h4-9,15-16,22,26,28H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	MNYRTHFYWWGGTK-WDAWEKNVSA-N	50024313	CHEMBL2112971	Alpha-2C adrenergic receptor		 3.6								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024313&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11236591	277286513		CHEMBL2112971					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127544	COc1ccc2C3=NO[C@@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)[C@@H]3C=Cc2c1	InChI=1S/C28H29N3O2/c1-32-24-9-11-25-23(17-24)8-10-26-27(33-29-28(25)26)19-31-14-12-30(13-15-31)18-20-6-7-21-4-2-3-5-22(21)16-20/h2-11,16-17,26-27H,12-15,18-19H2,1H3/t26-,27-/m0/s1	UAHLUVNKSWGJEK-SVBPBHIXSA-N	50024310	CHEMBL2112972	Alpha-2C adrenergic receptor		 6.3								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024310&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71461647	277286510		CHEMBL2112972					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127547	COc1cc2NC[C@H]3[C@H](CN4CCN(CCOc5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31FN4O4/c1-31-22-13-19-21(14-23(22)32-2)27-15-20-24(34-28-25(19)20)16-30-9-7-29(8-10-30)11-12-33-18-5-3-17(26)4-6-18/h3-6,13-14,20,24,27H,7-12,15-16H2,1-2H3/t20-,24-/m0/s1	AIWNTZODSQLIEU-RDPSFJRHSA-N	50024314	CHEMBL2112969	Alpha-2C adrenergic receptor		 1.6								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024314	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024314&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11431359	103934520		CHEMBL2112969				ZINC26398071	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127553	CN1C[C@H]2[C@H](CN3CCN(C\C=C\c4ccccc4)CC3)ON=C2c2ccccc12	InChI=1S/C25H30N4O/c1-27-18-22-24(30-26-25(22)21-11-5-6-12-23(21)27)19-29-16-14-28(15-17-29)13-7-10-20-8-3-2-4-9-20/h2-12,22,24H,13-19H2,1H3/b10-7+/t22-,24-/m0/s1	GHPKBFZQNLPFFZ-PTQQVUJNSA-N	50024312	CHEMBL2112970	Alpha-2C adrenergic receptor		 4.5								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024312&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11200476	277286512		CHEMBL2112970					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127561	COCC(=O)Oc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C28H33N3O5/c1-20(14-21-6-4-3-5-7-21)16-30-10-12-31(13-11-30)17-26-24-18-34-25-15-22(35-27(32)19-33-2)8-9-23(25)28(24)29-36-26/h3-9,14-15,24,26H,10-13,16-19H2,1-2H3/b20-14+/t24-,26-/m0/s1	DISVZQSFAXIOLP-FAPZGSLLSA-N	50163491	CHEMBL175853::Methoxy-acetic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-yl ester	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163491&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11214030	104049491		CHEMBL175853				ZINC22933299	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127564	COc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C26H31N3O3/c1-19(14-20-6-4-3-5-7-20)16-28-10-12-29(13-11-28)17-25-23-18-31-24-15-21(30-2)8-9-22(24)26(23)27-32-25/h3-9,14-15,23,25H,10-13,16-18H2,1-2H3/b19-14+/t23-,25-/m0/s1	UHVQVIBBKZFOBO-XDFBZRTDSA-N	50163494	(3R,3aS)-7-Methoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL176002	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163494&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44387789	104049494		CHEMBL176002				ZINC22933286	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127594	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	WZOMJNATDSYQHS-ZPWQMVEJSA-N	50131359	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328114	Alpha-2C adrenergic receptor		 6.2								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131359&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324765	104022543		CHEMBL328114					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127633	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(OC(=O)c4ccncc4)ccc32)CC1)=C/c1ccccc1	InChI=1S/C31H32N4O4/c1-22(17-23-5-3-2-4-6-23)19-34-13-15-35(16-14-34)20-29-27-21-37-28-18-25(7-8-26(28)30(27)33-39-29)38-31(36)24-9-11-32-12-10-24/h2-12,17-18,27,29H,13-16,19-21H2,1H3/b22-17+/t27-,29-/m0/s1	OLAGLCHGSUYVBF-HXSUMWGRSA-N	50163474	CHEMBL425324::Isonicotinic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-yl ester	Alpha-2C adrenergic receptor		 0.500000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163474&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11318438	104049474		CHEMBL425324				ZINC28111658	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127636	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(OC4CCCC4)ccc32)CC1)=C/c1ccccc1	InChI=1S/C30H37N3O3/c1-22(17-23-7-3-2-4-8-23)19-32-13-15-33(16-14-32)20-29-27-21-34-28-18-25(35-24-9-5-6-10-24)11-12-26(28)30(27)31-36-29/h2-4,7-8,11-12,17-18,24,27,29H,5-6,9-10,13-16,19-21H2,1H3/b22-17+/t27-,29-/m0/s1	RJLMZCSOGDTDNJ-HXSUMWGRSA-N	50163498	(3R,3aS)-7-Cyclopentyloxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL369378	Alpha-2C adrenergic receptor		 0.500000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163498&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11190988	104049498		CHEMBL369378				ZINC22933290	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127638	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JWYUBODPEUBFLH-FSTMKDAKSA-N	50131346	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91157	Alpha-2C adrenergic receptor		 0.100000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131346&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324800	104022530		CHEMBL91157				ZINC22930620	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127646	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	YMYZKGIHGMHZDL-WDAWEKNVSA-N	50131347	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419316	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131347&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324972	104022531		CHEMBL419316				ZINC22930623	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127647	CCOCCOCCOc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C31H41N3O5/c1-3-35-15-16-36-17-18-37-26-9-10-27-29(20-26)38-23-28-30(39-32-31(27)28)22-34-13-11-33(12-14-34)21-24(2)19-25-7-5-4-6-8-25/h4-10,19-20,28,30H,3,11-18,21-23H2,1-2H3/b24-19+/t28-,30-/m0/s1	LLFVSLMMRPXQFK-FPHSVDBKSA-N	50163475	(3R,3aS)-7-[2-(2-Ethoxy-ethoxy)-ethoxy]-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL179237	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163475&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11785961	104049475		CHEMBL179237				ZINC28117339	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127648	COc1cc2OC[C@H]3[C@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-11-9-30(10-12-31)16-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27H,9-12,16-18H2,1-2H3/t23-,27-/m0/s1	XHLHZPFSBCZVEA-HOFKKMOUSA-N	50131351	(3R,3aS)-7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL92860	Alpha-2C adrenergic receptor		 3.1								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131351&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324737	104022535		CHEMBL92860				ZINC22445308	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127704	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(OC(=O)C(C)(C)C)ccc32)CC1)=C/c1ccccc1	InChI=1S/C30H37N3O4/c1-21(16-22-8-6-5-7-9-22)18-32-12-14-33(15-13-32)19-27-25-20-35-26-17-23(36-29(34)30(2,3)4)10-11-24(26)28(25)31-37-27/h5-11,16-17,25,27H,12-15,18-20H2,1-4H3/b21-16+/t25-,27-/m0/s1	DGXYDPJRLWCWFV-ZXDVGYGBSA-N	50163484	2,2-Dimethyl-propionic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-yl ester::CHEMBL178588	Alpha-2C adrenergic receptor		 1.6								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163484&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11191321	104049484		CHEMBL178588				ZINC22933308	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127714	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	WZOMJNATDSYQHS-ZPWQMVEJSA-N	50131359	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328114	Alpha-2C adrenergic receptor		 8.8								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131359&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324765	104022543		CHEMBL328114					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127727	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JWYUBODPEUBFLH-FSTMKDAKSA-N	50131346	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91157	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131346&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324800	104022530		CHEMBL91157				ZINC22930620	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127731	COCCOc1ccc2C3=NO[C@@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)[C@@H]3COc2c1	InChI=1S/C28H35N3O4/c1-21(16-22-6-4-3-5-7-22)18-30-10-12-31(13-11-30)19-27-25-20-34-26-17-23(33-15-14-32-2)8-9-24(26)28(25)29-35-27/h3-9,16-17,25,27H,10-15,18-20H2,1-2H3/b21-16+/t25-,27-/m0/s1	VGYOOEDZRKNLKS-ZXDVGYGBSA-N	50163477	(3R,3aS)-7-(2-Methoxy-ethoxy)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL435352	Alpha-2C adrenergic receptor		 0.030000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163477&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11306100	104049477		CHEMBL435352				ZINC22582175	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127732	CC(=O)N1C[C@H]2[C@H](CN3CCN(CCC\C=C\c4ccccc4)CC3)ON=C2c2ccccc12	InChI=1S/C28H34N4O2/c1-22(33)32-20-25-27(34-29-28(25)24-13-7-8-14-26(24)32)21-31-18-16-30(17-19-31)15-9-3-6-12-23-10-4-2-5-11-23/h2,4-8,10-14,25,27H,3,9,15-21H2,1H3/b12-6+/t25-,27-/m0/s1	SNBRKKJCZXXNNL-MRGGPSPGSA-N	50163469	1-{(3R,3aR)-3-[4-((E)-5-Phenyl-pent-4-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-isoxazolo[4,3-c]quinolin-5-yl}-ethanone::CHEMBL426959	Alpha-2C adrenergic receptor		 11								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163469	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163469&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44387798	104049469		CHEMBL426959				ZINC28116712	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127734	C\C(CN1CCN(C[C@@H]2ON=C3[C@H]2COc2cc(OC(=O)C=C)ccc32)CC1)=C/c1ccccc1	InChI=1S/C28H31N3O4/c1-3-27(32)34-22-9-10-23-25(16-22)33-19-24-26(35-29-28(23)24)18-31-13-11-30(12-14-31)17-20(2)15-21-7-5-4-6-8-21/h3-10,15-16,24,26H,1,11-14,17-19H2,2H3/b20-15+/t24-,26-/m0/s1	QHCZSHHKZDDCEC-MSKIIMLESA-N	50163487	Acrylic acid (3R,3aS)-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-7-ylester::CHEMBL180322	Alpha-2C adrenergic receptor		 0.500000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163487&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11260018	104049487		CHEMBL180322				ZINC22933305	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50127768	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	WZOMJNATDSYQHS-ZPWQMVEJSA-N	50131359	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328114	Alpha-2C adrenergic receptor		 0.500000								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131359&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324765	104022543		CHEMBL328114					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50133583	C[C@H](N)Cn1ncc2ccc(O)cc12	InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	WBYHTZYHAFNBKW-ZETCQYMHSA-N	50180251	1-((S)-2-aminopropyl)-1H-indazol-6-ol::CHEMBL371300	Alpha-2C adrenergic receptor					 10000					ChEMBL	10.1021/jm050663x	10.7270/Q23B5ZQW	16392816			May, JA; Dantanarayana, AP; Zinke, PW; McLaughlin, MA; Sharif, NA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180251&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9834183	104065368		CHEMBL371300				ZINC00009096	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50136136	OC1(CCN(CCCC(=O)c2ccc(F)cc2)C1)c1ccc(Cl)cc1	InChI=1S/C20H21ClFNO2/c21-17-7-5-16(6-8-17)20(25)11-13-23(14-20)12-1-2-19(24)15-3-9-18(22)10-4-15/h3-10,25H,1-2,11-14H2	BETHXCLHMRGYBW-UHFFFAOYSA-N	50185474	(+)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::(-)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(-)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::4-[3-(4-Chloro-phenyl)-3-hydroxy-pyrrolidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one::4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::CHEMBL150161	Alpha-2C adrenergic receptor		 94								ChEMBL	10.1016/j.bmcl.2006.03.057	10.7270/Q2571BM5	16621538			Ablordeppey, SY; Lyles-Eggleston, M; Bricker, B; Zhang, W; Zhu, X; Goodman, C; Roth, BL	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185474&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9906978	104069685		CHEMBL150161				ZINC12356157	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50139570	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(Cl)ccc23)cc1	InChI=1S/C23H27ClN4/c1-15-14-28(12-11-27(15)4)20-8-6-19(7-9-20)26-23-16(2)17(3)25-22-13-18(24)5-10-21(22)23/h5-10,13,15H,11-12,14H2,1-4H3,(H,25,26)	QRWKSCTWTCHDII-UHFFFAOYSA-N	50418050	CHEMBL1689423	Alpha-2C adrenergic receptor		 8.3								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50418050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50418050&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10318507	163367074		CHEMBL1689423				ZINC66102877	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50152479	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2C adrenergic receptor		 160								ChEMBL	10.1021/jm990569e	10.7270/Q2251HDX	10715142			Ross, TM; Jetter, MC; McDonnell, ME; Boyd, RE; Connelly, CD; Martinez, RP; Lewis, MA; Codd, EE; Raffa, RB; Reitz, AB	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50152480	Cc1sc(C)c2C(CCCc12)c1cnc[nH]1	InChI=1S/C13H16N2S/c1-8-10-4-3-5-11(12-6-14-7-15-12)13(10)9(2)16-8/h6-7,11H,3-5H2,1-2H3,(H,14,15)	AOQYWVCOSJELMS-UHFFFAOYSA-N	50085676	4-(1,3-Dimethyl-4,5,6,7-tetrahydro-benzo[c]thiophen-4-yl)-1H-imidazole::CHEMBL30739	Alpha-2C adrenergic receptor		 205								ChEMBL	10.1021/jm990569e	10.7270/Q2251HDX	10715142			Ross, TM; Jetter, MC; McDonnell, ME; Boyd, RE; Connelly, CD; Martinez, RP; Lewis, MA; Codd, EE; Raffa, RB; Reitz, AB	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085676&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9816063	103985086		CHEMBL30739				ZINC03923487	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50152484	Cc1sc(C)c2c1CCC=C2c1cnc[nH]1	InChI=1S/C13H14N2S/c1-8-10-4-3-5-11(12-6-14-7-15-12)13(10)9(2)16-8/h5-7H,3-4H2,1-2H3,(H,14,15)	RLKWQKZPCMICPS-UHFFFAOYSA-N	50085677	4-(1,3-Dimethyl-6,7-dihydro-benzo[c]thiophen-4-yl)-1H-imidazole::CHEMBL284795	Alpha-2C adrenergic receptor		 26								ChEMBL	10.1021/jm990569e	10.7270/Q2251HDX	10715142			Ross, TM; Jetter, MC; McDonnell, ME; Boyd, RE; Connelly, CD; Martinez, RP; Lewis, MA; Codd, EE; Raffa, RB; Reitz, AB	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085677&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10220232	103985087		CHEMBL284795				ZINC00024132	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50152513	C1CC(c2cnc[nH]2)c2ccsc2C1	InChI=1S/C11H12N2S/c1-2-8(10-6-12-7-13-10)9-4-5-14-11(9)3-1/h4-8H,1-3H2,(H,12,13)	BFSPTAYUYXLBEU-UHFFFAOYSA-N	50085678	4-(4,5,6,7-Tetrahydro-benzo[b]thiophen-4-yl)-1H-imidazole::CHEMBL284213	Alpha-2C adrenergic receptor		 172								ChEMBL	10.1021/jm990569e	10.7270/Q2251HDX	10715142			Ross, TM; Jetter, MC; McDonnell, ME; Boyd, RE; Connelly, CD; Martinez, RP; Lewis, MA; Codd, EE; Raffa, RB; Reitz, AB	The R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085678&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9815633	103985088		CHEMBL284213				ZINC03923482	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50149427	C(C1COc2ccccc2O1)N1CCCN(Cc2nc(no2)-c2cccnc2Oc2ccccc2)CC1	InChI=1S/C28H29N5O4/c1-2-8-21(9-3-1)36-28-23(10-6-13-29-28)27-30-26(37-31-27)19-33-15-7-14-32(16-17-33)18-22-20-34-24-11-4-5-12-25(24)35-22/h1-6,8-13,22H,7,14-20H2	YWALOGYVALOLTL-UHFFFAOYSA-N	50263725	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-((3-(2-phenoxypyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)-1,4-diazepane::CHEMBL491420	Alpha-2C adrenergic receptor		 1.7								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263725&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579272	104111964		CHEMBL491420				ZINC40424119	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50149428	O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1cccc(c1)C#N	InChI=1S/C29H31N5O4/c30-19-22-6-3-7-23(18-22)38-29-25(8-4-11-32-29)28(35)31-12-15-33-13-5-14-34(17-16-33)20-24-21-36-26-9-1-2-10-27(26)37-24/h1-4,6-11,18,24H,5,12-17,20-21H2,(H,31,35)	YGAFMXXNJBOVBA-UHFFFAOYSA-N	50263621	2-(3-cyanophenoxy)-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL515331	Alpha-2C adrenergic receptor		 1.9								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263621&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579187	104111894		CHEMBL515331				ZINC40918054	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50149431	C(CN1CCCN(CC2COc3ccccc3O2)CC1)OCc1cccnc1Oc1ccccc1	InChI=1S/C28H33N3O4/c1-2-9-24(10-3-1)35-28-23(8-6-13-29-28)21-32-19-18-30-14-7-15-31(17-16-30)20-25-22-33-26-11-4-5-12-27(26)34-25/h1-6,8-13,25H,7,14-22H2	AFRRMVBYOMNLHN-UHFFFAOYSA-N	50263724	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-(2-((2-phenoxypyridin-3-yl)methoxy)ethyl)-1,4-diazepane::CHEMBL491419	Alpha-2C adrenergic receptor		 6.8								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263724&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579271	104111963		CHEMBL491419				ZINC45498778	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50149435	O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1	InChI=1S/C28H32N4O4/c33-27(24-10-6-13-30-28(24)36-22-8-2-1-3-9-22)29-14-17-31-15-7-16-32(19-18-31)20-23-21-34-25-11-4-5-12-26(25)35-23/h1-6,8-13,23H,7,14-21H2,(H,29,33)	RNPCOHCWKNMBRI-UHFFFAOYSA-N	50263619	CHEMBL477816::N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)-2-phenoxynicotinamide	Alpha-2C adrenergic receptor		 5								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263619&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579185	104111892		CHEMBL477816				ZINC40421976	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50149436	COc1ccccc1N1CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C20H24N2O3/c1-23-18-7-3-2-6-17(18)22-12-10-21(11-13-22)14-16-15-24-19-8-4-5-9-20(19)25-16/h2-9,16H,10-15H2,1H3	IQDINXFLUAYBCC-UHFFFAOYSA-N	50263618	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-(2-methoxyphenyl)piperazine::CHEMBL518592	Alpha-2C adrenergic receptor		 33								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263618&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579184	104111891		CHEMBL518592				ZINC20775759	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50149445	C(C1CCc2ccccc2O1)N1CCN(Cc2ccccc2)CC1	InChI=1S/C21H26N2O/c1-2-6-18(7-3-1)16-22-12-14-23(15-13-22)17-20-11-10-19-8-4-5-9-21(19)24-20/h1-9,20H,10-17H2	AJZBPCAHQHCXMX-UHFFFAOYSA-N	50159018	1-Benzyl-4-chroman-2-ylmethyl-piperazine::1-benzyl-4-((3,4-dihydro-2H-chromen-2-yl)methyl)piperazine::CHEMBL179648	Alpha-2C adrenergic receptor		 20								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159018&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10758200	104045618		CHEMBL179648				ZINC22445891	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50149453	CCCCOc1cccc(n1)C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H36N4O4/c1-2-3-18-32-25-11-6-8-22(28-25)26(31)27-12-15-29-13-7-14-30(17-16-29)19-21-20-33-23-9-4-5-10-24(23)34-21/h4-6,8-11,21H,2-3,7,12-20H2,1H3,(H,27,31)	RVIXAJHMKWFIKC-UHFFFAOYSA-N	50263673	6-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)picolinamide::CHEMBL476569	Alpha-2C adrenergic receptor		 0.600000								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263673&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579230	104111926		CHEMBL476569				ZINC40917448	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50149455	CCCCOc1ncccc1C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H36N4O4/c1-2-3-18-32-26-22(8-6-11-28-26)25(31)27-12-15-29-13-7-14-30(17-16-29)19-21-20-33-23-9-4-5-10-24(23)34-21/h4-6,8-11,21H,2-3,7,12-20H2,1H3,(H,27,31)	OYOGQACTFBHTOD-UHFFFAOYSA-N	50263672	2-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL514837	Alpha-2C adrenergic receptor		 0.800000								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263672&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579229	104111925		CHEMBL514837				ZINC40408846	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50149460	O=C(NCCN1CCCN(C[C@H]2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1	InChI=1S/C28H32N4O4/c33-27(24-10-6-13-30-28(24)36-22-8-2-1-3-9-22)29-14-17-31-15-7-16-32(19-18-31)20-23-21-34-25-11-4-5-12-26(25)35-23/h1-6,8-13,23H,7,14-21H2,(H,29,33)/t23-/m0/s1	RNPCOHCWKNMBRI-QHCPKHFHSA-N	50263774	(S)-N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide::CHEMBL524153	Alpha-2C adrenergic receptor		 1.9								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263774&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25110718	104111991		CHEMBL524153				ZINC40951657	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50149461	CC(C)(C)Nc1ncccc1C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H37N5O3/c1-26(2,3)29-24-21(8-6-11-27-24)25(32)28-12-15-30-13-7-14-31(17-16-30)18-20-19-33-22-9-4-5-10-23(22)34-20/h4-6,8-11,20H,7,12-19H2,1-3H3,(H,27,29)(H,28,32)	IPSCUIDJZTXJJO-UHFFFAOYSA-N	50263671	2-(tert-butylamino)-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL477608	Alpha-2C adrenergic receptor		 0.500000								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263671&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579228	104111924		CHEMBL477608				ZINC40916745	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50161237	CN1C(=O)C[C@@H](C(C(=O)NCCCN2CCC(CC2)(C#N)c2ccc(F)cc2)=C1C)c1ccc(F)c(F)c1	InChI=1S/C29H31F3N4O2/c1-19-27(23(17-26(37)35(19)2)20-4-9-24(31)25(32)16-20)28(38)34-12-3-13-36-14-10-29(18-33,11-15-36)21-5-7-22(30)8-6-21/h4-9,16,23H,3,10-15,17H2,1-2H3,(H,34,38)/t23-/m1/s1	PEDXQUUSXXYPJU-HSZRJFAPSA-N	50090330	(R)-4-(3,4-Difluoro-phenyl)-1,2-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL291166	Alpha-2C adrenergic receptor		 1096								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090330	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090330&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44289035	103988825		CHEMBL291166				ZINC29389673	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50161243	CC1=C([C@H](CC(=O)N1)c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)(C#N)c1ccc(F)cc1C#N	InChI=1S/C29H28F3N5O2/c1-18-27(22(15-26(38)36-18)19-3-6-24(31)25(32)14-19)28(39)35-9-2-10-37-11-7-29(17-34,8-12-37)23-5-4-21(30)13-20(23)16-33/h3-6,13-14,22H,2,7-12,15H2,1H3,(H,35,39)(H,36,38)/t22-/m1/s1	KAXNWVHHUKHNDK-JOCHJYFZSA-N	50090335	(R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL42335	Alpha-2C adrenergic receptor		 4677.0								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090335&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44288847	103988830		CHEMBL42335				ZINC29392999	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50161246	CN1C(=O)C[C@@H](C(C(=O)NCCCN2CCC(CC2)(C#N)c2ccc(F)cc2C#N)=C1C)c1ccc(F)c(F)c1	InChI=1S/C30H30F3N5O2/c1-19-28(23(16-27(39)37(19)2)20-4-7-25(32)26(33)15-20)29(40)36-10-3-11-38-12-8-30(18-35,9-13-38)24-6-5-22(31)14-21(24)17-34/h4-7,14-15,23H,3,8-13,16H2,1-2H3,(H,36,40)/t23-/m1/s1	LEVRYVCMBBJQLU-HSZRJFAPSA-N	50090333	(R)-4-(3,4-Difluoro-phenyl)-1,2-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL43594	Alpha-2C adrenergic receptor		 6531								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090333	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090333&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44288877	103988828		CHEMBL43594				ZINC29393193	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50161260	CC1=C([C@H](CC(=O)N1)c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)(C#N)c1ccc(F)cc1F	InChI=1S/C28H28F4N4O2/c1-17-26(20(15-25(37)35-17)18-3-6-22(30)24(32)13-18)27(38)34-9-2-10-36-11-7-28(16-33,8-12-36)21-5-4-19(29)14-23(21)31/h3-6,13-14,20H,2,7-12,15H2,1H3,(H,34,38)(H,35,37)/t20-/m1/s1	RLMGUPUESXPDFJ-HXUWFJFHSA-N	50090338	(R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(2,4-difluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL295001	Alpha-2C adrenergic receptor		 1995								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090338&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44288874	103988833		CHEMBL295001				ZINC29393174	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50161274	CN1C(=O)C[C@@H](C(C(=O)NCCCN2CCC(CC2)c2ccc(F)cc2C#N)=C1C)c1ccc(F)c(F)c1	InChI=1S/C29H31F3N4O2/c1-18-28(24(16-27(37)35(18)2)20-4-7-25(31)26(32)15-20)29(38)34-10-3-11-36-12-8-19(9-13-36)23-6-5-22(30)14-21(23)17-33/h4-7,14-15,19,24H,3,8-13,16H2,1-2H3,(H,34,38)/t24-/m1/s1	DLMPCEBSXNLTAT-XMMPIXPASA-N	50090328	(R)-4-(3,4-Difluoro-phenyl)-1,2-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL288772	Alpha-2C adrenergic receptor		 3846.0								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090328&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10436842	103988823		CHEMBL288772				ZINC03975459	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50161275	CN1C(=O)C[C@@H](C(C(=O)NCCCN2CCC(CC2)(C#N)c2ccc(F)cc2F)=C1C)c1ccc(F)c(F)c1	InChI=1S/C29H30F4N4O2/c1-18-27(21(16-26(38)36(18)2)19-4-7-23(31)25(33)14-19)28(39)35-10-3-11-37-12-8-29(17-34,9-13-37)22-6-5-20(30)15-24(22)32/h4-7,14-15,21H,3,8-13,16H2,1-2H3,(H,35,39)/t21-/m1/s1	WIVOLWKUZIBRAF-OAQYLSRUSA-N	50090326	(R)-4-(3,4-Difluoro-phenyl)-1,2-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(2,4-difluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL295395	Alpha-2C adrenergic receptor		 1905								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090326	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090326&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44288769	103988821		CHEMBL295395				ZINC29392774	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50161296	CC1=C([C@H](CC(=O)N1)c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)c1ccc(F)cc1	InChI=1S/C27H30F3N3O2/c1-17-26(22(16-25(34)32-17)20-5-8-23(29)24(30)15-20)27(35)31-11-2-12-33-13-9-19(10-14-33)18-3-6-21(28)7-4-18/h3-8,15,19,22H,2,9-14,16H2,1H3,(H,31,35)(H,32,34)/t22-/m1/s1	FKKPXTRMLVLGJG-JOCHJYFZSA-N	50090332	(R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL43860	Alpha-2C adrenergic receptor		 313								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090332	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090332&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44288945	103988827		CHEMBL43860				ZINC29391912	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50161300	CC1=C([C@H](CC(=O)N1)c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)c1ccc(F)cc1C#N	InChI=1S/C28H29F3N4O2/c1-17-27(23(15-26(36)34-17)19-3-6-24(30)25(31)14-19)28(37)33-9-2-10-35-11-7-18(8-12-35)22-5-4-21(29)13-20(22)16-32/h3-6,13-14,18,23H,2,7-12,15H2,1H3,(H,33,37)(H,34,36)/t23-/m1/s1	RQTZTSPFFYDZKA-HSZRJFAPSA-N	50090339	(R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL43491	Alpha-2C adrenergic receptor		 1479								ChEMBL	10.1016/s0960-894x(99)00696-4	10.7270/Q2445KQK	10937710			Nantermet, PG; Barrow, JC; Selnick, HG; Homnick, CF; Freidinger, RM; Chang, RS; O'Malley, SS; Reiss, DR; Broten, TP; Ransom, RW; Pettibone, DJ; Olah, T; Forray, C	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090339	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090339&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9827677	103988834		CHEMBL43491				ZINC29392541	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50161844	C[C@@H]1OC(=O)N([C@H]1c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)c1ccc(F)cc1	InChI=1S/C25H28F3N3O3/c1-16-23(19-5-8-21(27)22(28)15-19)31(25(33)34-16)24(32)29-11-2-12-30-13-9-18(10-14-30)17-3-6-20(26)7-4-17/h3-8,15-16,18,23H,2,9-14H2,1H3,(H,29,32)/t16-,23+/m0/s1	DTYAFBJXWWLRMA-QMHKHESXSA-N	50090647	(4S,5S)-4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxazolidine-3-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::(4S,5S)-4-(3,4-difluorophenyl)-N-(3-(4-(4-fluorophenyl)piperidin-1-yl)propyl)-5-methyl-2-oxooxazolidine-3-carboxamide::4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxazolidine-3-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL96467::SNAP-7915	Alpha-2C adrenergic receptor		>45								ChEMBL	10.1021/jm000085e	10.7270/Q2PZ582K	10956183			Lagu, B; Tian, D; Jeon, Y; Li, C; Wetzel, JM; Nagarathnam, D; Shen, Q; Forray, C; Chang, RS; Broten, TP; Ransom, RW; Chan, TB; O'Malley, SS; Schorn, TW; Rodrigues, AD; Kassahun, K; Pettibone, DJ; Freidinger, RO; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090647&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9830741	103989116		CHEMBL96467				ZINC03921115	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50208131	[O-][N+](=O)c1ccccc1S(=O)(=O)NC[C@H]1CC[C@H](CNCC2CCc3ccccc3C2)CC1	InChI=1S/C25H33N3O4S/c29-28(30)24-7-3-4-8-25(24)33(31,32)27-18-20-11-9-19(10-12-20)16-26-17-21-13-14-22-5-1-2-6-23(22)15-21/h1-8,19-21,26-27H,9-18H2/t19-,20-,21?	ISSSVYKMIIAPTH-YGQOYYDZSA-N	50114974	2-Nitro-N-(4-{[(1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-amino]-methyl}-cyclohexylmethyl)-benzenesulfonamide::2-nitro-N-((4-(((1,2,3,4-tetrahydronaphthalen-2-yl)methylamino)methyl)cyclohexyl)methyl)benzenesulfonamide::CHEMBL299879	Alpha-2C adrenergic receptor		 100								ChEMBL	10.1016/s0960-894x(02)00287-1	10.7270/Q2JD4W4S	12067557			Islam, I; Dhanoa, D; Finn, J; Du, P; Walker, MW; Salon, JA; Zhang, J; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114974	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114974&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9982218	104008962		CHEMBL299879				ZINC08022499	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50208177	COc1cc2NCC3C(CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H34N4O3/c1-19(13-20-7-5-4-6-8-20)17-30-9-11-31(12-10-30)18-26-22-16-28-23-15-25(33-3)24(32-2)14-21(23)27(22)29-34-26/h4-8,13-15,22,26,28H,9-12,16-18H2,1-3H3/b19-13+	JODRRUQCPGURFJ-CPNJWEJPSA-N	50209684	CHEMBL390718::cis-(+)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole	Alpha-2C adrenergic receptor		 8.30								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209684&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44424854	104086408		CHEMBL390718				ZINC28654956	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50208228	COc1cc2OCC3C(CN4CCN(C\C=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H30FN3O4/c1-31-23-14-20-22(15-24(23)32-2)33-17-21-25(34-28-26(20)21)16-30-12-10-29(11-13-30)9-3-4-18-5-7-19(27)8-6-18/h3-8,14-15,21,25H,9-13,16-17H2,1-2H3/b4-3+	CVKQUGPVDVFRAT-ONEGZZNKSA-N	50209685	CHEMBL226636::cis-(+)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole	Alpha-2C adrenergic receptor		 72								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209685&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44424855	104086409		CHEMBL226636				ZINC28654969	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50208242	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H32FN3O4/c1-18(12-19-4-6-20(28)7-5-19)15-30-8-10-31(11-9-30)16-26-22-17-34-23-14-25(33-3)24(32-2)13-21(23)27(22)29-35-26/h4-7,12-14,22,26H,8-11,15-17H2,1-3H3/b18-12+/t22-,26-/m0/s1	UCNOTTVNPRSTFW-XSFNXXSESA-N	50146518	(3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL318235::R-226161::cis-(+)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole	Alpha-2C adrenergic receptor		 10.00								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146518&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16655023	104035107		CHEMBL318235				ZINC26742166	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223283	CCc1ccccc1OC(C)C1=NCCN1	InChI=1S/C13H18N2O/c1-3-11-6-4-5-7-12(11)16-10(2)13-14-8-9-15-13/h4-7,10H,3,8-9H2,1-2H3,(H,14,15)	RUFDXBQFEDFKDE-UHFFFAOYSA-N	50419886	CHEMBL156336	Alpha-2C adrenergic receptor		 288								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419886	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419886&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371745	163368910		CHEMBL156336				ZINC27712342	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223285	CC(Oc1c(CC=C)cccc1CC=C)C1=NCCN1	InChI=1S/C17H22N2O/c1-4-7-14-9-6-10-15(8-5-2)16(14)20-13(3)17-18-11-12-19-17/h4-6,9-10,13H,1-2,7-8,11-12H2,3H3,(H,18,19)	YAYASQTZIRSRFB-UHFFFAOYSA-N	50419885	CHEMBL157206	Alpha-2C adrenergic receptor		 129								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419885&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371744	163368909		CHEMBL157206				ZINC27712333	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222251	Cc1ccccc1COC1=NCCN1	InChI=1S/C11H14N2O/c1-9-4-2-3-5-10(9)8-14-11-12-6-7-13-11/h2-5H,6-8H2,1H3,(H,12,13)	LGTDYALRCIBCMI-UHFFFAOYSA-N	50415141	CHEMBL576819	Alpha-2C adrenergic receptor					 2884					ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415141&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487958	163364165		CHEMBL576819				ZINC45299429	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222252	CCCc1ccccc1C(C)OC1=NCCN1	InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)	CKZOGIXOGHVXNW-UHFFFAOYSA-N	50415138	CHEMBL576078	Alpha-2C adrenergic receptor					 25					ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415138&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487955	163364162		CHEMBL576078				ZINC45301117	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222253	CCCc1ccccc1COC1=NCCN1	InChI=1S/C13H18N2O/c1-2-5-11-6-3-4-7-12(11)10-16-13-14-8-9-15-13/h3-4,6-7H,2,5,8-10H2,1H3,(H,14,15)	XBWFPEVESQMIBM-UHFFFAOYSA-N	50415140	CHEMBL569933	Alpha-2C adrenergic receptor					 155					ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415140&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487962	163364164		CHEMBL569933				ZINC45255608	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222255	CC(OC1=NCCN1)c1ccccc1C1CC1	InChI=1S/C14H18N2O/c1-10(17-14-15-8-9-16-14)12-4-2-3-5-13(12)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	BGPHEWUAKSHOBD-UHFFFAOYSA-N	50415139	CHEMBL576623	Alpha-2C adrenergic receptor					 40					ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415139&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487956	163364163		CHEMBL576623				ZINC45290491	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222259	C(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15)	YAORIDZYZDUZCM-UHFFFAOYSA-N	50027060	2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole::2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole (cirazoline)::CHEMBL13852::CIRAZOLINE	Alpha-2C adrenergic receptor		 550								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027060&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2765	103936642		CHEMBL13852	DB09202	515		ZINC00001160	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222262	CC(OC1=NCCN1)c1ccccc1CC=C	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MCAGSCISRRGDGQ-UHFFFAOYSA-N	50415136	CHEMBL570973	Alpha-2C adrenergic receptor		 85								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415136&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487145	163364160		CHEMBL570973				ZINC45257642	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222263	CC(OC1=NCCN1)c1ccccc1C	InChI=1S/C12H16N2O/c1-9-5-3-4-6-11(9)10(2)15-12-13-7-8-14-12/h3-6,10H,7-8H2,1-2H3,(H,13,14)	NGYGSYPEYBVPQK-UHFFFAOYSA-N	50415137	CHEMBL570863	Alpha-2C adrenergic receptor					 63					ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415137&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487089	163364161		CHEMBL570863				ZINC45254599	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222308	C[C@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m0/s1	OGOLMGZJNRNULQ-ZDUSSCGKSA-N	50417354	CHEMBL396013	Alpha-2C adrenergic receptor		 302								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417354&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10333157	163366378		CHEMBL396013				ZINC00009140	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222309	C[C@@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m1/s1	OGOLMGZJNRNULQ-CYBMUJFWSA-N	50417353	CHEMBL242265	Alpha-2C adrenergic receptor		 977								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417353&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11043720	163366377		CHEMBL242265				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222310	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2C adrenergic receptor					 50					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222312	C[C@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m0/s1	MNMDMCKHXVHLAW-NSHDSACASA-N	50417343	CHEMBL1276140	Alpha-2C adrenergic receptor		 71								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417343&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836301	163366367		CHEMBL1276140				ZINC40957102	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222313	C[C@@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m1/s1	MNMDMCKHXVHLAW-LLVKDONJSA-N	50417342	CHEMBL1276139	Alpha-2C adrenergic receptor					 186					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836302	163366366		CHEMBL1276139				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222317	C[C@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m0/s1	QYCJTZDZQXSXSC-JTQLQIEISA-N	50417346	CHEMBL1276220	Alpha-2C adrenergic receptor		 63								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417346&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836303	163366370		CHEMBL1276220					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222318	CC(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	QYCJTZDZQXSXSC-UHFFFAOYSA-N	50417344	CHEMBL1276218	Alpha-2C adrenergic receptor					 40					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417344&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44549156	163366368		CHEMBL1276218				ZINC64393121	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222320	C[C@@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m1/s1	QYCJTZDZQXSXSC-SNVBAGLBSA-N	50417345	CHEMBL1276219	Alpha-2C adrenergic receptor					 126					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417345&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836304	163366369		CHEMBL1276219					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222321	C[C@@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	NMSAVNXFCXMJJY-GFCCVEGCSA-N	50218115	(R)-2-[1-(3'-nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL242693	Alpha-2C adrenergic receptor					 10					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218115&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757089	104091931		CHEMBL242693				ZINC13585593	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222329	C[C@@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	NMSAVNXFCXMJJY-GFCCVEGCSA-N	50218115	(R)-2-[1-(3'-nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL242693	Alpha-2C adrenergic receptor		 234								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218115&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757089	104091931		CHEMBL242693				ZINC13585593	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222336	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2C adrenergic receptor		 200								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222341	C[C@H](Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)/t12-/m0/s1	XGMNRALXOWECNG-LBPRGKRZSA-N	50417352	CHEMBL1278085	Alpha-2C adrenergic receptor					 2512					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417352&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836307	163366376		CHEMBL1278085					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222342	C[C@@H](Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	XGMNRALXOWECNG-GFCCVEGCSA-N	50417351	CHEMBL1278084	Alpha-2C adrenergic receptor					 25					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417351&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836308	163366375		CHEMBL1278084					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223382	CC(Oc1c(Cl)cccc1Cl)C1=NCCN1	InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)	KSMAGQUYOIHWFS-UHFFFAOYSA-N	50019646	2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline::2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL17860::lofexidine	Alpha-2C adrenergic receptor					 1.4					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019646&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			30668	103930569	51368	CHEMBL17860	DB04948			ZINC00005626	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223385	CC(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)	SEKAQUSPSDPIAN-UHFFFAOYSA-N	50419878	CHEMBL1956195	Alpha-2C adrenergic receptor					 2					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419878&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345628	163368902		CHEMBL1956195				ZINC73294767	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223386	CCOc1ccccc1OC(C)C1=NCCN1	InChI=1S/C13H18N2O2/c1-3-16-11-6-4-5-7-12(11)17-10(2)13-14-8-9-15-13/h4-7,10H,3,8-9H2,1-2H3,(H,14,15)	DYQQPAOLMYPZKE-UHFFFAOYSA-N	50419879	CHEMBL1956196	Alpha-2C adrenergic receptor					 10000					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419879	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419879&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57399145	163368903		CHEMBL1956196				ZINC73312418	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223387	CC(Oc1ccccc1C(F)(F)F)C1=NCCN1	InChI=1S/C12H13F3N2O/c1-8(11-16-6-7-17-11)18-10-5-3-2-4-9(10)12(13,14)15/h2-5,8H,6-7H2,1H3,(H,16,17)	BFKLSSIIDDEGQB-UHFFFAOYSA-N	50419875	CHEMBL1956193	Alpha-2C adrenergic receptor					 794					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419875	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419875&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57395663	163368899		CHEMBL1956193				ZINC73314893	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223388	CC(Oc1ccccc1C(C)=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(2)12-6-4-5-7-13(12)17-11(3)14-15-8-9-16-14/h4-7,11H,1,8-9H2,2-3H3,(H,15,16)	HVCWUSZDSFHZDW-UHFFFAOYSA-N	50419877	CHEMBL1956194	Alpha-2C adrenergic receptor					 115					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419877	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419877&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345627	163368901		CHEMBL1956194				ZINC73313031	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223389	COc1ccccc1OC(C)C1=NCCN1	InChI=1S/C12H16N2O2/c1-9(12-13-7-8-14-12)16-11-6-4-3-5-10(11)15-2/h3-6,9H,7-8H2,1-2H3,(H,13,14)	SQPFWLZXWYXMCI-UHFFFAOYSA-N	50419881	CHEMBL1956199	Alpha-2C adrenergic receptor					 9772					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419881&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57402717	163368905		CHEMBL1956199				ZINC73312431	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223390	CC(Oc1ccccc1S(C)(=O)=O)C1=NCCN1	InChI=1S/C12H16N2O3S/c1-9(12-13-7-8-14-12)17-10-5-3-4-6-11(10)18(2,15)16/h3-6,9H,7-8H2,1-2H3,(H,13,14)	BUVSDNNKXQXCRO-UHFFFAOYSA-N	50419882	CHEMBL1956200	Alpha-2C adrenergic receptor					 316					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419882	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419882&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57400959	163368906		CHEMBL1956200				ZINC73312436	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223391	CC(Oc1ccccc1OC1CC1)C1=NCCN1	InChI=1S/C14H18N2O2/c1-10(14-15-8-9-16-14)17-12-4-2-3-5-13(12)18-11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	OHLOMHGVALXPJP-UHFFFAOYSA-N	50419880	CHEMBL1956197	Alpha-2C adrenergic receptor					 48					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419880&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345629	163368904		CHEMBL1956197				ZINC73312422	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223395	CC(C)c1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H20N2O/c1-10(2)12-6-4-5-7-13(12)17-11(3)14-15-8-9-16-14/h4-7,10-11H,8-9H2,1-3H3,(H,15,16)	DAEHQHNTEAMXQC-UHFFFAOYSA-N	50419876	CHEMBL266613	Alpha-2C adrenergic receptor					 398					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419876&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269089	163368900		CHEMBL266613				ZINC13805985	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223399	CC(Oc1ccccc1C(C)=O)C1=NCCN1	InChI=1S/C13H16N2O2/c1-9(16)11-5-3-4-6-12(11)17-10(2)13-14-7-8-15-13/h3-6,10H,7-8H2,1-2H3,(H,14,15)	LHYRGWVECGKEOM-UHFFFAOYSA-N	50419888	CHEMBL1956202	Alpha-2C adrenergic receptor					 200					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419888&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57395731	163368912		CHEMBL1956202				ZINC73312444	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223400	CC(Oc1c(cccc1-c1ccccc1)-c1ccccc1)C1=NCCN1	InChI=1S/C23H22N2O/c1-17(23-24-15-16-25-23)26-22-20(18-9-4-2-5-10-18)13-8-14-21(22)19-11-6-3-7-12-19/h2-14,17H,15-16H2,1H3,(H,24,25)	YCFVUTASHGKCKL-UHFFFAOYSA-N	50419873	CHEMBL1956203	Alpha-2C adrenergic receptor					 79					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419873	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419873&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57395732	163368897		CHEMBL1956203				ZINC73311702	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223402	CC(Oc1ccccc1C=O)C1=NCCN1	InChI=1S/C12H14N2O2/c1-9(12-13-6-7-14-12)16-11-5-3-2-4-10(11)8-15/h2-5,8-9H,6-7H2,1H3,(H,13,14)	UQOROHPPKUMVNP-UHFFFAOYSA-N	50419883	CHEMBL1956201	Alpha-2C adrenergic receptor					 100					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419883	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419883&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57402718	163368907		CHEMBL1956201				ZINC73312440	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223404	CCc1cccc(CC)c1OC(C)C1=NCCN1	InChI=1S/C15H22N2O/c1-4-12-7-6-8-13(5-2)14(12)18-11(3)15-16-9-10-17-15/h6-8,11H,4-5,9-10H2,1-3H3,(H,16,17)	OXGCVSXSSWZTMU-UHFFFAOYSA-N	50419884	CHEMBL157955	Alpha-2C adrenergic receptor					 28					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419884&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371864	163368908		CHEMBL157955				ZINC27705893	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223406	CC(Oc1c(C)cccc1C)C1=NCCN1	InChI=1S/C13H18N2O/c1-9-5-4-6-10(2)12(9)16-11(3)13-14-7-8-15-13/h4-6,11H,7-8H2,1-3H3,(H,14,15)	JWAAXMLRAVOKBQ-UHFFFAOYSA-N	50419889	CHEMBL155866	Alpha-2C adrenergic receptor					 28					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419889&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371755	163368913		CHEMBL155866				ZINC27710505	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223407	CC(C)Oc1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H20N2O2/c1-10(2)17-12-6-4-5-7-13(12)18-11(3)14-15-8-9-16-14/h4-7,10-11H,8-9H2,1-3H3,(H,15,16)	YQBKUZKHVPTFOO-UHFFFAOYSA-N	50419887	CHEMBL14208	Alpha-2C adrenergic receptor		 398								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419887	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419887&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269140	163368911		CHEMBL14208				ZINC13805996	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223409	CC(Oc1ccccc1Cl)C1=NCCN1	InChI=1S/C11H13ClN2O/c1-8(11-13-6-7-14-11)15-10-5-3-2-4-9(10)12/h2-5,8H,6-7H2,1H3,(H,13,14)	ARHDCTCZSSOSFG-UHFFFAOYSA-N	50419890	CHEMBL1956191	Alpha-2C adrenergic receptor					 166					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419890&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345625	163368914		CHEMBL1956191				ZINC73314283	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223410	CC(Oc1ccccc1Br)C1=NCCN1	InChI=1S/C11H13BrN2O/c1-8(11-13-6-7-14-11)15-10-5-3-2-4-9(10)12/h2-5,8H,6-7H2,1H3,(H,13,14)	NFGYJBCMYUYKCI-UHFFFAOYSA-N	50419874	CHEMBL1956192	Alpha-2C adrenergic receptor					 10					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419874&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345626	163368898		CHEMBL1956192				ZINC73315479	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223413	C1CN=C(N1)[C@@H]1CO[C@@H](CO1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-17-12(9-16-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12-/m0/s1	MPFNVJVLRBBPHX-RYUDHWBXSA-N	50419925	CHEMBL1956899	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419925	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419925&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57393066	163368949		CHEMBL1956899				ZINC73296457	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223426	C[C@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m0/s1	MNMDMCKHXVHLAW-NSHDSACASA-N	50417343	CHEMBL1276140	Alpha-2C adrenergic receptor					 25					ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417343&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836301	163366367		CHEMBL1276140				ZINC40957102	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223427	C[C@@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m1/s1	SEKAQUSPSDPIAN-LLVKDONJSA-N	50420341	CHEMBL2089155	Alpha-2C adrenergic receptor		 234								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420341&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70693375	163369365		CHEMBL2089155					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223429	C[C@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m0/s1	SEKAQUSPSDPIAN-NSHDSACASA-N	50420342	CHEMBL2089156	Alpha-2C adrenergic receptor		 275								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70695474	163369366		CHEMBL2089156					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223431	CC(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)	SEKAQUSPSDPIAN-UHFFFAOYSA-N	50419878	CHEMBL1956195	Alpha-2C adrenergic receptor		 275								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419878&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345628	163368902		CHEMBL1956195				ZINC73294767	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223434	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2C adrenergic receptor		 85								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50223441	C[C@@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m1/s1	MNMDMCKHXVHLAW-LLVKDONJSA-N	50417342	CHEMBL1276139	Alpha-2C adrenergic receptor					 186					ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836302	163366366		CHEMBL1276139				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222353	C[C@@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	NMSAVNXFCXMJJY-GFCCVEGCSA-N	50218115	(R)-2-[1-(3'-nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL242693	Alpha-2C adrenergic receptor		 257								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218115&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757089	104091931		CHEMBL242693				ZINC13585593	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222356	CC(Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)	IAIZHDGEGFGNMO-UHFFFAOYSA-N	50417347	CHEMBL385310	Alpha-2C adrenergic receptor					 93					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417347&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11371902	163366371		CHEMBL385310				ZINC13585567	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222358	CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)	XGMNRALXOWECNG-UHFFFAOYSA-N	50417350	CHEMBL374584	Alpha-2C adrenergic receptor		 18								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417350&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11346584	163366374		CHEMBL374584				ZINC13585584	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222368	C[C@@H](Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)/t11-/m1/s1	IAIZHDGEGFGNMO-LLVKDONJSA-N	50417348	CHEMBL1276247	Alpha-2C adrenergic receptor		 316								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417348&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836306	163366372		CHEMBL1276247					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222371	C[C@H](Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)/t11-/m0/s1	IAIZHDGEGFGNMO-NSHDSACASA-N	50417349	CHEMBL1276248	Alpha-2C adrenergic receptor		 126								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417349&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836305	163366373		CHEMBL1276248					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50222372	C[C@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m0/s1	NMSAVNXFCXMJJY-LBPRGKRZSA-N	50417341	CHEMBL397753	Alpha-2C adrenergic receptor		 537								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417341&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757182	163366365		CHEMBL397753				ZINC13585595	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50221922	C1CN=C(N1)C1COc2c(O1)cccc2-c1ccccc1	InChI=1S/C17H16N2O2/c1-2-5-12(6-3-1)13-7-4-8-14-16(13)20-11-15(21-14)17-18-9-10-19-17/h1-8,15H,9-11H2,(H,18,19)	MQSPJCMZCOHHPI-UHFFFAOYSA-N	50412256	CHEMBL493272	Alpha-2C adrenergic receptor		 832								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412256&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906201	163361280		CHEMBL493272				ZINC40431295	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50221929	CC(Oc1ccccc1\C=N\OCc1ccccc1)C1=NCCN1	InChI=1S/C19H21N3O2/c1-15(19-20-11-12-21-19)24-18-10-6-5-9-17(18)13-22-23-14-16-7-3-2-4-8-16/h2-10,13,15H,11-12,14H2,1H3,(H,20,21)/b22-13+	KUWSYGHOSHDWCB-LPYMAVHISA-N	50412246	CHEMBL495097	Alpha-2C adrenergic receptor					 3548					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412246&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906197	163361270		CHEMBL495097				ZINC40957611	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50221930	C1CN=C(N1)C(Oc1ccccc1-c1ccccc1)c1ccccc1	InChI=1S/C22H20N2O/c1-3-9-17(10-4-1)19-13-7-8-14-20(19)25-21(22-23-15-16-24-22)18-11-5-2-6-12-18/h1-14,21H,15-16H2,(H,23,24)	XXOSLSPHUHLICG-UHFFFAOYSA-N	50412257	CHEMBL523048	Alpha-2C adrenergic receptor		 204								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412257&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906200	163361281		CHEMBL523048				ZINC40957110	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50221931	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2C adrenergic receptor					 50					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50221933	CC(Oc1ccccc1C1CCCC1)C1=NCCN1	InChI=1S/C16H22N2O/c1-12(16-17-10-11-18-16)19-15-9-5-4-8-14(15)13-6-2-3-7-13/h4-5,8-9,12-13H,2-3,6-7,10-11H2,1H3,(H,17,18)	WIQCERUTOBWUOL-UHFFFAOYSA-N	50412244	CHEMBL495096	Alpha-2C adrenergic receptor					 10					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412244&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906199	163361268		CHEMBL495096				ZINC40430700	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50221935	CC(Oc1ccccc1C1CCCCC1)C1=NCCN1	InChI=1S/C17H24N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h5-6,9-10,13-14H,2-4,7-8,11-12H2,1H3,(H,18,19)	RIMQFOFQYZBTDB-UHFFFAOYSA-N	50412258	CHEMBL451229	Alpha-2C adrenergic receptor					 21					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412258&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23622576	163361282		CHEMBL451229				ZINC40836200	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50221938	CCO\N=C\c1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H19N3O2/c1-3-18-17-10-12-6-4-5-7-13(12)19-11(2)14-15-8-9-16-14/h4-7,10-11H,3,8-9H2,1-2H3,(H,15,16)/b17-10+	BVWLLEDYRCHASI-LICLKQGHSA-N	50412247	CHEMBL492639	Alpha-2C adrenergic receptor					 1000					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412247&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906196	163361271		CHEMBL492639				ZINC45506721	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50221949	CO\N=C\c1ccccc1OC(C)C1=NCCN1	InChI=1S/C13H17N3O2/c1-10(13-14-7-8-15-13)18-12-6-4-3-5-11(12)9-16-17-2/h3-6,9-10H,7-8H2,1-2H3,(H,14,15)/b16-9+	YTQHOBJMFUQZEK-CXUHLZMHSA-N	50412248	CHEMBL442815	Alpha-2C adrenergic receptor					 501					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412248&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906160	163361272		CHEMBL442815				ZINC40822924	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50221952	C1CN=C(N1)C1COc2cccc(-c3ccccc3)c2O1	InChI=1S/C17H16N2O2/c1-2-5-12(6-3-1)13-7-4-8-14-16(13)21-15(11-20-14)17-18-9-10-19-17/h1-8,15H,9-11H2,(H,18,19)	LOGUSYSMQQMCJG-UHFFFAOYSA-N	50412253	CHEMBL522151	Alpha-2C adrenergic receptor		 692								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412253&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906241	163361277		CHEMBL522151				ZINC40949724	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50221955	CC(Oc1ccccc1CN=O)C1=NCCN1	InChI=1S/C12H15N3O2/c1-9(12-13-6-7-14-12)17-11-5-3-2-4-10(11)8-15-16/h2-5,9H,6-8H2,1H3,(H,13,14)	FZLNIHYBYXMHEO-UHFFFAOYSA-N	50412249	CHEMBL493675	Alpha-2C adrenergic receptor					 126					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412249&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91900410	163361273		CHEMBL493675				ZINC40430963	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50221958	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2C adrenergic receptor					 58					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50216450	CN1CCN=C1Cc1cccnc1	InChI=1S/C10H13N3/c1-13-6-5-12-10(13)7-9-3-2-4-11-8-9/h2-4,8H,5-7H2,1H3	YXPIBYSOCFGTHG-UHFFFAOYSA-N	50094968	3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-pyridine::CHEMBL313631	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1021/jm020188s	10.7270/Q2ZW1K88	12361399			Ferretti, G; Dukat, M; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Damaj, MI; Martin, BR; Glennon, RA	Universita di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094968	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094968&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10035109	103992788		CHEMBL313631				ZINC13487902	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239100	COc1cc2OCC3C(CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+	YMYZKGIHGMHZDL-DJKKODMXSA-N	50131365	7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL327875	Alpha-2C adrenergic receptor		 0.600000								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131365	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131365&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325049	104022549		CHEMBL327875				ZINC22930667	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239104	COc1cc2OCC3C(CN4CCN(CCc5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O4/c1-29-22-14-19-21(15-23(22)30-2)31-17-20-24(32-26-25(19)20)16-28-12-10-27(11-13-28)9-8-18-6-4-3-5-7-18/h3-7,14-15,20,24H,8-13,16-17H2,1-2H3	AVVCHEPXGGYIRM-UHFFFAOYSA-N	50131362	7,8-Dimethoxy-3-(4-phenethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL92496	Alpha-2C adrenergic receptor		 89								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131362&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325079	104022546		CHEMBL92496				ZINC26646298	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50238995	COc1ccc2C3=NOC(CN4CCN(C\C=C\c5ccccc5)CC4)C3COc2c1	InChI=1S/C25H29N3O3/c1-29-20-9-10-21-23(16-20)30-18-22-24(31-26-25(21)22)17-28-14-12-27(13-15-28)11-5-8-19-6-3-2-4-7-19/h2-10,16,22,24H,11-15,17-18H2,1H3/b8-5+	WDCPMDKQCCZVEW-VMPITWQZSA-N	50131348	7-Methoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL90247	Alpha-2C adrenergic receptor		 1.9								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131348&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324906	104022532		CHEMBL90247				ZINC26651989	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50238999	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C/c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6-/t21-,25-/m0/s1	WZOMJNATDSYQHS-VTYJTISCSA-N	50131349	(R)-7,8-Dimethoxy-3-[4-((Z)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL420830	Alpha-2C adrenergic receptor		 35.0								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131349&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330571	104022533		CHEMBL420830				ZINC26654774	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239007	COc1cc2OCC3C(CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+	WZOMJNATDSYQHS-RMKNXTFCSA-N	50131355	7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL93489	Alpha-2C adrenergic receptor		 6.2								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131355&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9846548	104022539		CHEMBL93489				ZINC22930650	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239009	COc1cc2OCC3C(CN4CCN(CCC(=O)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O5/c1-31-23-14-19-22(15-24(23)32-2)33-17-20-25(34-27-26(19)20)16-29-12-10-28(11-13-29)9-8-21(30)18-6-4-3-5-7-18/h3-7,14-15,20,25H,8-13,16-17H2,1-2H3	AWPNMWRTPSQMFC-UHFFFAOYSA-N	50131358	3-[4-(7,8-Dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-3-ylmethyl)-piperazin-1-yl]-1-phenyl-propan-1-one::CHEMBL328735	Alpha-2C adrenergic receptor		 5.3								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131358	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131358&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325075	104022542		CHEMBL328735				ZINC26644321	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239023	COc1cc2OCC3C(CN4CCN(Cc5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C24H29N3O4/c1-28-21-12-18-20(13-22(21)29-2)30-16-19-23(31-25-24(18)19)15-27-10-8-26(9-11-27)14-17-6-4-3-5-7-17/h3-7,12-13,19,23H,8-11,14-16H2,1-2H3	VUTLJDGDPMZCOA-UHFFFAOYSA-N	50131363	3-(4-Benzyl-piperazin-1-ylmethyl)-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL90843	Alpha-2C adrenergic receptor		 89								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131363&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324900	104022547		CHEMBL90843				ZINC26645413	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239026	COc1cc2OCC3C(CN4CCN(Cc5cccc6ccccc56)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-12-10-30(11-13-31)16-20-8-5-7-19-6-3-4-9-21(19)20/h3-9,14-15,23,27H,10-13,16-18H2,1-2H3	JNMSRIDVZNTYJE-UHFFFAOYSA-N	50131364	7,8-Dimethoxy-3-(4-naphthalen-1-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91297	Alpha-2C adrenergic receptor		 89								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131364&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325028	104022548		CHEMBL91297				ZINC26644039	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239029	COc1cccc2[C@H](CN(C)CCc3ccc4ccoc4c3)CCCc12	InChI=1S/C23H27NO2/c1-24(13-11-17-9-10-18-12-14-26-23(18)15-17)16-19-5-3-7-21-20(19)6-4-8-22(21)25-2/h4,6,8-10,12,14-15,19H,3,5,7,11,13,16H2,1-2H3/t19-/m0/s1	MHPMXTGKTXJIDI-IBGZPJMESA-N	50057128	(2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-amine::A-80426::CHEMBL268258	Alpha-2C adrenergic receptor		 2.1								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057128&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9928332	103953208		CHEMBL268258				ZINC03810797	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239030	COc1cc2OCC3C(CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+	JWYUBODPEUBFLH-CPNJWEJPSA-N	50131353	7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL93171	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131353&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325050	104022537		CHEMBL93171				ZINC22930658	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239036	COc1cc2OC[C@H]3[C@H](CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-11-9-30(10-12-31)16-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27H,9-12,16-18H2,1-2H3/t23-,27-/m0/s1	XHLHZPFSBCZVEA-HOFKKMOUSA-N	50131351	(3R,3aS)-7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL92860	Alpha-2C adrenergic receptor		 9.50								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131351&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324737	104022535		CHEMBL92860				ZINC22445308	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239051	COc1cc2OCC3C(CN4CCN(CC5=Cc6ccccc6C5)CC4)ON=C3c2cc1OC	InChI=1S/C27H31N3O4/c1-31-24-13-21-23(14-25(24)32-2)33-17-22-26(34-28-27(21)22)16-30-9-7-29(8-10-30)15-18-11-19-5-3-4-6-20(19)12-18/h3-6,11,13-14,22,26H,7-10,12,15-17H2,1-2H3	AQDOXXILINNVJB-UHFFFAOYSA-N	50131356	3-[4-(1H-Inden-2-ylmethyl)-piperazin-1-ylmethyl]-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328377	Alpha-2C adrenergic receptor		 4.7								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131356&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324859	104022540		CHEMBL328377				ZINC26655851	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239058	COc1cc2OCC3C(CN4CCN(CCCc5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H33N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-5,7-8,15-16,21,25H,6,9-14,17-18H2,1-2H3	WYFPZXUWZCKNMJ-UHFFFAOYSA-N	50131366	7,8-Dimethoxy-3-[4-(3-phenyl-propyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL90419	Alpha-2C adrenergic receptor		 1.9								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131366	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131366&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324725	104022550		CHEMBL90419				ZINC26646012	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239062	C(\C=C\c1ccccc1)N1CCN(CC2ON=C3C2COc2ccccc32)CC1	InChI=1S/C24H27N3O2/c1-2-7-19(8-3-1)9-6-12-26-13-15-27(16-14-26)17-23-21-18-28-22-11-5-4-10-20(22)24(21)25-29-23/h1-11,21,23H,12-18H2/b9-6+	MUUSOYWTPTTZII-RMKNXTFCSA-N	50131360	3-[4-((E)-3-Phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL90943	Alpha-2C adrenergic receptor		 1.7								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131360&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324937	104022544		CHEMBL90943				ZINC26648694	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239067	COc1ccc2OCC3C(CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2c1	InChI=1S/C25H29N3O3/c1-29-20-9-10-23-21(16-20)25-22(18-30-23)24(31-26-25)17-28-14-12-27(13-15-28)11-5-8-19-6-3-2-4-7-19/h2-10,16,22,24H,11-15,17-18H2,1H3/b8-5+	FJABWASNVHOPLU-VMPITWQZSA-N	50131350	8-Methoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL422597	Alpha-2C adrenergic receptor		 2.3								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131350&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324887	104022534		CHEMBL422597				ZINC26646476	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239068	COc1cc2OCC3C(CN4CCN(Cc5cc6ccccc6s5)CC4)ON=C3c2cc1OC	InChI=1S/C26H29N3O4S/c1-30-22-12-19-21(13-23(22)31-2)32-16-20-24(33-27-26(19)20)15-29-9-7-28(8-10-29)14-18-11-17-5-3-4-6-25(17)34-18/h3-6,11-13,20,24H,7-10,14-16H2,1-2H3	IHCKEJIXIYLTFT-UHFFFAOYSA-N	50131368	3-(4-Benzo[b]thiophen-2-ylmethyl-piperazin-1-ylmethyl)-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL94435	Alpha-2C adrenergic receptor		 89								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131368	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131368&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324860	104022552		CHEMBL94435				ZINC26655867	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239071	COc1cc2OCC3C(CN4CCN(Cc5cnc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C27H30N4O4/c1-32-24-12-20-23(13-25(24)33-2)34-17-21-26(35-29-27(20)21)16-31-9-7-30(8-10-31)15-18-11-19-5-3-4-6-22(19)28-14-18/h3-6,11-14,21,26H,7-10,15-17H2,1-2H3	SWMRFMZFBGUQMK-UHFFFAOYSA-N	50131361	7,8-Dimethoxy-3-(4-quinolin-3-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91824	Alpha-2C adrenergic receptor		 30								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131361&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325027	104022545		CHEMBL91824				ZINC26644023	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239074	COc1cc2OCC3C(CN4CCN(Cc5csc6ccccc56)CC4)ON=C3c2cc1OC	InChI=1S/C26H29N3O4S/c1-30-22-11-19-21(12-23(22)31-2)32-15-20-24(33-27-26(19)20)14-29-9-7-28(8-10-29)13-17-16-34-25-6-4-3-5-18(17)25/h3-6,11-12,16,20,24H,7-10,13-15H2,1-2H3	SNKCREOVGWDJDI-UHFFFAOYSA-N	50131352	3-(4-Benzo[b]thiophen-3-ylmethyl-piperazin-1-ylmethyl)-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL93801	Alpha-2C adrenergic receptor		 13								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131352&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325044	104022536		CHEMBL93801				ZINC26657477	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239079	Fc1ccc2CC(CC3CNC=N3)Cc2c1	InChI=1S/C13H15FN2/c14-12-2-1-10-3-9(4-11(10)6-12)5-13-7-15-8-16-13/h1-2,6,8-9,13H,3-5,7H2,(H,15,16)	HBMJQYDGBNSZMC-UHFFFAOYSA-N	50131357	4-(5-Fluoro-indan-2-ylmethyl)-4,5-dihydro-1H-imidazole::CHEMBL90997::S-34324	Alpha-2C adrenergic receptor		 19								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131357&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10220053	104022541		CHEMBL90997				ZINC26652869	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239080	COc1cc2OCC3C(CN4CCN(Cc5ccc6ccccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C28H31N3O4/c1-32-25-14-22-24(15-26(25)33-2)34-18-23-27(35-29-28(22)23)17-31-11-9-30(10-12-31)16-19-7-8-20-5-3-4-6-21(20)13-19/h3-8,13-15,23,27H,9-12,16-18H2,1-2H3	XHLHZPFSBCZVEA-UHFFFAOYSA-N	50131354	7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL94129	Alpha-2C adrenergic receptor		 3.1								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131354&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44215744	104022538		CHEMBL94129				ZINC22930675	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50239082	COc1cc2OCC3C(CN4CCN(Cc5ccc6ncccc6c5)CC4)ON=C3c2cc1OC	InChI=1S/C27H30N4O4/c1-32-24-13-20-23(14-25(24)33-2)34-17-21-26(35-29-27(20)21)16-31-10-8-30(9-11-31)15-18-5-6-22-19(12-18)4-3-7-28-22/h3-7,12-14,21,26H,8-11,15-17H2,1-2H3	APNJYYQXBHETAR-UHFFFAOYSA-N	50131367	7,8-Dimethoxy-3-(4-quinolin-6-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL90966	Alpha-2C adrenergic receptor		 36								ChEMBL	10.1016/s0960-894x(03)00525-0	10.7270/Q2T43SGC	12873501			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Cid, JM; De Lucas, AI; Fernandez, J; Martinez, S; Nieto, C; Pastor, J; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131367	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131367&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44325038	104022551		CHEMBL90966				ZINC26646277	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50250008	COc1ccc2c(c1)[nH]c1c(C)nccc21	InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	BXNJHAXVSOCGBA-UHFFFAOYSA-N	100152	7-methoxy-1-methyl-9H-beta-carboline;hydrochloride::7-methoxy-1-methyl-9H-pyrido[3,4-b]indole;hydrochloride::HARMINE::Harmine hydrochloride::MLS002153910::SMR001233259::cid_5359389	Alpha-2C adrenergic receptor		 810								ChEMBL	10.1016/j.bmcl.2003.09.027	10.7270/Q2D21X2G	14643338			Grella, B; Teitler, M; Smith, C; Herrick-Davis, K; Glennon, RA	Virginia Commonwealth University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=100152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=100152&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	HRM	7X9D,5Y86,2Z5X,3ANR,2Z5Y	5280953	252663240	28121		DB07919		C06538	ZINC18847046	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50250016	COc1ccc2c3CCNCc3[nH]c2c1	InChI=1S/C12H14N2O/c1-15-8-2-3-9-10-4-5-13-7-12(10)14-11(9)6-8/h2-3,6,13-14H,4-5,7H2,1H3	SCIRNASYBOGBOO-UHFFFAOYSA-N	50132097	7-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL6310	Alpha-2C adrenergic receptor		 1740								ChEMBL	10.1016/j.bmcl.2003.09.027	10.7270/Q2D21X2G	14643338			Grella, B; Teitler, M; Smith, C; Herrick-Davis, K; Glennon, RA	Virginia Commonwealth University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132097	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132097&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			599482	104023122		CHEMBL6310				ZINC13587968	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50266446	CN1CCc2c(C1)c1cccc3-c4ccccc4CCn2c13	InChI=1S/C20H20N2/c1-21-11-10-19-18(13-21)17-8-4-7-16-15-6-3-2-5-14(15)9-12-22(19)20(16)17/h2-8H,9-13H2,1H3	XKGPHJMKJBEURD-UHFFFAOYSA-N	50445614	CHEMBL3104093	Alpha-2C adrenergic receptor		 446								ChEMBL	10.1016/j.bmcl.2014.05.016	10.7270/Q28K7BQ5	24863744			Rajagopalan, P; Tracey, H; Chen, Z; Bandyopadhyaya, A; Veeraraghavan, S; Rajagopalan, DR; Salvemini, D; McPhee, I; Viswanadha, S; Rajagopalan, R	University of Missouri	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50445614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50445614&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			73213196	194943510		CHEMBL3104093					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50267792	COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C	InChI=1S/C16H19NO3S/c1-11-9-12(2)16(13(3)10-11)17-21(18,19)15-7-5-14(20-4)6-8-15/h5-10,17H,1-4H3	FQUAFMNPXPXOJE-UHFFFAOYSA-N	50044849	CHEMBL3311308	Alpha-2C adrenergic receptor					<31623					ChEMBL	10.1016/j.bmcl.2014.05.012	10.7270/Q2CC1292	24881566			Sparks, SM; Chen, G; Collins, JL; Danger, D; Dock, ST; Jayawickreme, C; Jenkinson, S; Laudeman, C; Leesnitzer, MA; Liang, X; Maloney, P; McCoy, DC; Moncol, D; Rash, V; Rimele, T; Vulimiri, P; Way, JM; Ross, S	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044849&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			743974	103975962	46932	CHEMBL3311308				ZINC02522581	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268943	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H30FN3O4/c1-31-23-14-20-22(15-24(23)32-2)33-17-21-25(34-28-26(20)21)16-30-12-10-29(11-13-30)9-3-4-18-5-7-19(27)8-6-18/h3-8,14-15,21,25H,9-13,16-17H2,1-2H3/b4-3+/t21-,25-/m0/s1	CVKQUGPVDVFRAT-SKBIIQSFSA-N	50146500	(3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419894	Alpha-2C adrenergic receptor		 23								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146500&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330609	104035089		CHEMBL419894				ZINC26741131	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268944	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5cccs5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O4S/c1-17(11-18-5-4-10-33-18)14-27-6-8-28(9-7-27)15-24-20-16-31-21-13-23(30-3)22(29-2)12-19(21)25(20)26-32-24/h4-5,10-13,20,24H,6-9,14-16H2,1-3H3/b17-11+/t20-,24-/m0/s1	JPNJJWFOEQLLSP-FJEUJEQTSA-N	50146498	(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-thiophen-2-yl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL98646	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146498&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330653	104035087		CHEMBL98646				ZINC26740265	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268947	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5cc(F)ccc5F)CC4)ON=C3c2cc1OC	InChI=1S/C27H31F2N3O4/c1-17(10-18-11-19(28)4-5-22(18)29)14-31-6-8-32(9-7-31)15-26-21-16-35-23-13-25(34-3)24(33-2)12-20(23)27(21)30-36-26/h4-5,10-13,21,26H,6-9,14-16H2,1-3H3/b17-10+/t21-,26-/m0/s1	NDIXVNRNAFQAJZ-HNQXZTCOSA-N	50146501	(3R,3aS)-3-{4-[3-(2,5-Difluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL319119	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146501&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11225779	104035090		CHEMBL319119				ZINC22582170	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268948	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5cccc(F)c5)CC4)ON=C3c2cc1OC	InChI=1S/C26H30FN3O4/c1-31-23-14-20-22(15-24(23)32-2)33-17-21-25(34-28-26(20)21)16-30-11-9-29(10-12-30)8-4-6-18-5-3-7-19(27)13-18/h3-7,13-15,21,25H,8-12,16-17H2,1-2H3/b6-4+/t21-,25-/m0/s1	WNCGPEYSCDVJNB-UHRPABQZSA-N	50146503	(3R,3aS)-3-{4-[3-(3-Fluoro-phenyl)-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL95218	Alpha-2C adrenergic receptor		 0.700000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146503&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330598	104035092		CHEMBL95218				ZINC26730263	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268949	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5cccs5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O4S/c1-17(24-5-4-12-33-24)6-7-27-8-10-28(11-9-27)15-23-19-16-31-20-14-22(30-3)21(29-2)13-18(20)25(19)26-32-23/h4-6,12-14,19,23H,7-11,15-16H2,1-3H3/b17-6+/t19-,23-/m0/s1	JBOWHEDUACRXHK-KJMIXQDXSA-N	50146502	(3R,3aS)-7,8-Dimethoxy-3-[4-(3-thiophen-2-yl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL100879	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146502&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330168	104035091		CHEMBL100879				ZINC26742847	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268950	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(20-7-5-4-6-8-20)9-10-29-11-13-30(14-12-29)17-26-22-18-33-23-16-25(32-3)24(31-2)15-21(23)27(22)28-34-26/h4-9,15-16,22,26H,10-14,17-18H2,1-3H3/b19-9+/t22-,26-/m0/s1	YMYZKGIHGMHZDL-WDAWEKNVSA-N	50131347	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419316	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131347&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324972	104022531		CHEMBL419316				ZINC22930623	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268952	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5F)CC4)ON=C3c2cc1OC	InChI=1S/C26H30FN3O4/c1-31-23-14-19-22(15-24(23)32-2)33-17-20-25(34-28-26(19)20)16-30-12-10-29(11-13-30)9-5-7-18-6-3-4-8-21(18)27/h3-8,14-15,20,25H,9-13,16-17H2,1-2H3/b7-5+/t20-,25-/m0/s1	LEHLBTBBMZYRBK-UABDMCKPSA-N	50146505	(3R,3aS)-3-{4-[3-(2-Fluoro-phenyl)-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL319573	Alpha-2C adrenergic receptor		 2.8								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146505&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330584	104035094		CHEMBL319573				ZINC26735504	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268954	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccco5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O5/c1-17(11-18-5-4-10-31-18)14-27-6-8-28(9-7-27)15-24-20-16-32-21-13-23(30-3)22(29-2)12-19(21)25(20)26-33-24/h4-5,10-13,20,24H,6-9,14-16H2,1-3H3/b17-11+/t20-,24-/m0/s1	KSQAWHREGPMSBF-FJEUJEQTSA-N	50146504	(3R,3aS)-3-[4-(3-Furan-2-yl-2-methyl-allyl)-piperazin-1-ylmethyl]-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL99916	Alpha-2C adrenergic receptor		 0.500000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146504&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330645	104035093		CHEMBL99916				ZINC26730711	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268955	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C/c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6-/t21-,25-/m0/s1	WZOMJNATDSYQHS-VTYJTISCSA-N	50146499	(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL420830	Alpha-2C adrenergic receptor		 9.5								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146499&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330571	104035088		CHEMBL420830				ZINC22930607	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268956	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5cccc(F)c5)CC4)ON=C3c2cc1OC	InChI=1S/C27H32FN3O4/c1-18(11-19-5-4-6-20(28)12-19)15-30-7-9-31(10-8-30)16-26-22-17-34-23-14-25(33-3)24(32-2)13-21(23)27(22)29-35-26/h4-6,11-14,22,26H,7-10,15-17H2,1-3H3/b18-11+/t22-,26-/m0/s1	JCJVFLLBDXJJPW-QJOHKBMMSA-N	50146506	(3R,3aS)-3-{4-[3-(3-Fluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL263424	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146506&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330617	104035095		CHEMBL263424				ZINC26742934	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268958	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccc(Cl)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H30ClN3O4/c1-31-23-14-20-22(15-24(23)32-2)33-17-21-25(34-28-26(20)21)16-30-12-10-29(11-13-30)9-3-4-18-5-7-19(27)8-6-18/h3-8,14-15,21,25H,9-13,16-17H2,1-2H3/b4-3+/t21-,25-/m0/s1	HJACXCAXDLNLEL-SKBIIQSFSA-N	50146508	(3R,3aS)-3-{4-[3-(4-Chloro-phenyl)-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL101411	Alpha-2C adrenergic receptor		 10								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146508&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330621	104035097		CHEMBL101411				ZINC26747193	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268963	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H32FN3O4/c1-18(19-4-6-20(28)7-5-19)8-9-30-10-12-31(13-11-30)16-26-22-17-34-23-15-25(33-3)24(32-2)14-21(23)27(22)29-35-26/h4-8,14-15,22,26H,9-13,16-17H2,1-3H3/b18-8+/t22-,26-/m0/s1	BLAVUEWHVKGIIM-FHYDSMICSA-N	50146512	(3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-but-2-enyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL98541	Alpha-2C adrenergic receptor		 0.300000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146512	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146512&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10480357	104035101		CHEMBL98541				ZINC26741071	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268967	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccsc5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O4S/c1-17(18-5-11-33-16-18)4-6-27-7-9-28(10-8-27)14-24-20-15-31-21-13-23(30-3)22(29-2)12-19(21)25(20)26-32-24/h4-5,11-13,16,20,24H,6-10,14-15H2,1-3H3/b17-4+/t20-,24-/m0/s1	BSOFNSGMVOMVLM-MWXPQOEXSA-N	50146513	(3R,3aS)-7,8-Dimethoxy-3-[4-(3-thiophen-3-yl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328195	Alpha-2C adrenergic receptor		 0.300000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146513&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330369	104035102		CHEMBL328195				ZINC26738287	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268968	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccc(O)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O5/c1-18(19-4-6-20(31)7-5-19)8-9-29-10-12-30(13-11-29)16-26-22-17-34-23-15-25(33-3)24(32-2)14-21(23)27(22)28-35-26/h4-8,14-15,22,26,31H,9-13,16-17H2,1-3H3/b18-8+/t22-,26-/m0/s1	VMLJCXYBTLCGDU-FHYDSMICSA-N	50146511	4-{(E)-3-[4-((3R,3aS)-7,8-Dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-3-ylmethyl)-piperazin-1-yl]-1-methyl-propenyl}-phenol::CHEMBL329065	Alpha-2C adrenergic receptor		 0.600000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146511	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146511&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330368	104035100		CHEMBL329065				ZINC26738282	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268970	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccccc5OC)CC4)ON=C3c2cc1OC	InChI=1S/C28H35N3O5/c1-19(20-7-5-6-8-23(20)32-2)9-10-30-11-13-31(14-12-30)17-27-22-18-35-24-16-26(34-4)25(33-3)15-21(24)28(22)29-36-27/h5-9,15-16,22,27H,10-14,17-18H2,1-4H3/b19-9+/t22-,27-/m0/s1	NJTFNKZJGXSOMJ-CACUEOBGSA-N	50146514	(3R,3aS)-7,8-Dimethoxy-3-{4-[3-(2-methoxy-phenyl)-but-2-enyl]-piperazin-1-ylmethyl}-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL101361	Alpha-2C adrenergic receptor		 0.900000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146514	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146514&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330857	104035103		CHEMBL101361				ZINC26746329	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268971	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H31N3O4/c1-30-23-15-20-22(16-24(23)31-2)32-18-21-25(33-27-26(20)21)17-29-13-11-28(12-14-29)10-6-9-19-7-4-3-5-8-19/h3-9,15-16,21,25H,10-14,17-18H2,1-2H3/b9-6+/t21-,25-/m0/s1	WZOMJNATDSYQHS-ZPWQMVEJSA-N	50131359	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328114	Alpha-2C adrenergic receptor		 6.2								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131359&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324765	104022543		CHEMBL328114					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268972	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccc(F)cc5F)CC4)ON=C3c2cc1OC	InChI=1S/C27H31F2N3O4/c1-17(19-5-4-18(28)12-22(19)29)6-7-31-8-10-32(11-9-31)15-26-21-16-35-23-14-25(34-3)24(33-2)13-20(23)27(21)30-36-26/h4-6,12-14,21,26H,7-11,15-16H2,1-3H3/b17-6+/t21-,26-/m0/s1	KOMMMRWKUHRBSF-NMDKTAKLSA-N	50146507	(3R,3aS)-3-{4-[3-(2,4-Difluoro-phenyl)-but-2-enyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL328631	Alpha-2C adrenergic receptor		 0.800000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146507&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10028898	104035096		CHEMBL328631				ZINC26733925	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268982	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H33N3O4/c1-19(13-20-7-5-4-6-8-20)16-29-9-11-30(12-10-29)17-26-22-18-33-23-15-25(32-3)24(31-2)14-21(23)27(22)28-34-26/h4-8,13-15,22,26H,9-12,16-18H2,1-3H3/b19-13+/t22-,26-/m0/s1	JWYUBODPEUBFLH-FSTMKDAKSA-N	50131346	(3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL91157	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131346&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44324800	104022530		CHEMBL91157				ZINC22930620	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268986	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5cccnc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H32N4O4/c1-18(11-19-5-4-6-27-14-19)15-29-7-9-30(10-8-29)16-25-21-17-33-22-13-24(32-3)23(31-2)12-20(22)26(21)28-34-25/h4-6,11-14,21,25H,7-10,15-17H2,1-3H3/b18-11+/t21-,25-/m0/s1	GEBHRBBICJPJRU-BFAOIYKGSA-N	50146509	(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-pyridin-3-yl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL98889	Alpha-2C adrenergic receptor		 2.1								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146509	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146509&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330679	104035098		CHEMBL98889				ZINC26738217	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268995	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccco5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O5/c1-17(20-5-4-12-31-20)6-7-27-8-10-28(11-9-27)15-24-19-16-32-21-14-23(30-3)22(29-2)13-18(21)25(19)26-33-24/h4-6,12-14,19,24H,7-11,15-16H2,1-3H3/b17-6+/t19-,24-/m0/s1	SYULCMQGHBLEEJ-GOANZFJNSA-N	50146516	(3R,3aS)-3-[4-(3-Furan-2-yl-but-2-enyl)-piperazin-1-ylmethyl]-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL319530	Alpha-2C adrenergic receptor		 0.400000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146516	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146516&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330114	104035105		CHEMBL319530				ZINC26741684	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268997	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccccc5OC)CC4)ON=C3c2cc1OC	InChI=1S/C28H35N3O5/c1-19(13-20-7-5-6-8-23(20)32-2)16-30-9-11-31(12-10-30)17-27-22-18-35-24-15-26(34-4)25(33-3)14-21(24)28(22)29-36-27/h5-8,13-15,22,27H,9-12,16-18H2,1-4H3/b19-13+/t22-,27-/m0/s1	PYXVPLGVUNHGEJ-VKAKAFFBSA-N	50146515	(3R,3aS)-7,8-Dimethoxy-3-{4-[3-(2-methoxy-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL99868	Alpha-2C adrenergic receptor		 0.400000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330635	104035104		CHEMBL99868				ZINC26735150	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50268999	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H32FN3O4/c1-18(12-19-4-6-20(28)7-5-19)15-30-8-10-31(11-9-30)16-26-22-17-34-23-14-25(33-3)24(32-2)13-21(23)27(22)29-35-26/h4-7,12-14,22,26H,8-11,15-17H2,1-3H3/b18-12+/t22-,26-/m0/s1	UCNOTTVNPRSTFW-XSFNXXSESA-N	50146518	(3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL318235::R-226161::cis-(+)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole	Alpha-2C adrenergic receptor		 0.700000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146518&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16655023	104035107		CHEMBL318235				ZINC26742166	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50269006	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccsc5)CC4)ON=C3c2cc1OC	InChI=1S/C25H31N3O4S/c1-17(10-18-4-9-33-16-18)13-27-5-7-28(8-6-27)14-24-20-15-31-21-12-23(30-3)22(29-2)11-19(21)25(20)26-32-24/h4,9-12,16,20,24H,5-8,13-15H2,1-3H3/b17-10+/t20-,24-/m0/s1	IPLOTOHAAAUTMK-UDUWVDIRSA-N	50146510	(3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-thiophen-3-yl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL101596	Alpha-2C adrenergic receptor		 0.200000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146510	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146510&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330668	104035099		CHEMBL101596				ZINC26743248	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50269009	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5cccc(F)c5F)CC4)ON=C3c2cc1OC	InChI=1S/C27H31F2N3O4/c1-17(11-18-5-4-6-21(28)26(18)29)14-31-7-9-32(10-8-31)15-25-20-16-35-22-13-24(34-3)23(33-2)12-19(22)27(20)30-36-25/h4-6,11-13,20,25H,7-10,14-16H2,1-3H3/b17-11+/t20-,25-/m0/s1	HQDWMIAYEGTBSF-DAJVNYJUSA-N	50146517	(3R,3aS)-3-{4-[3-(2,3-Difluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL419336	Alpha-2C adrenergic receptor		 0.700000								ChEMBL	10.1016/j.bmcl.2004.03.031	10.7270/Q20864SM	15125959			Pastor, J; Alcazar, J; Alvarez, RM; Andres, JI; Cid, JM; De Lucas, AI; Diaz, A; Fernandez, J; Font, LM; Iturrino, L; Lafuente, C; Martinez, S; Bakker, MH; Biesmans, I; Heylen, LI; Megens, AA	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146517&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44330427	104035106		CHEMBL419336				ZINC26735979	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50309007	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC2[C@H]1C(=O)NCCCNC(=O)[C@@H]1[C@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@H]3C[C@@H]12	InChI=1S/C43H54N6O4/c50-36-12-10-24-22-48-18-14-28-26-6-1-3-8-32(26)46-40(28)34(48)20-30(24)38(36)42(52)44-16-5-17-45-43(53)39-31-21-35-41-29(27-7-2-4-9-33(27)47-41)15-19-49(35)23-25(31)11-13-37(39)51/h1-4,6-9,24-25,30-31,34-39,46-47,50-51H,5,10-23H2,(H,44,52)(H,45,53)/t24-,25+,30-,31?,34-,35+,36-,37+,38+,39-/m1/s1	OIXDQFQFMZDLEJ-XXTHQMTASA-N	50167574	1N-{3-[2-hydroxy-(1R,2S,4aR,13bS)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]b-carbolin-1-ylcarboxamido]propyl}-2-hydroxy-(1S,2R,4aS,13bR,14aR)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquino[3,2-a]::CHEMBL371516	Alpha-2C adrenergic receptor		 8.5								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167574&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44402477	104052790		CHEMBL371516				ZINC95612558	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50309008	NCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC12	InChI=1S/C23H32N4O2/c24-9-3-10-25-23(29)21-17-12-19-22-16(15-4-1-2-5-18(15)26-22)8-11-27(19)13-14(17)6-7-20(21)28/h1-2,4-5,14,17,19-21,26,28H,3,6-13,24H2,(H,25,29)/t14-,17?,19-,20-,21+/m0/s1	DREAQJWFKWPENL-CVZXYRABSA-N	50167575	(1R,2S,4aR,13bS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid (3-amino-propyl)-amide::CHEMBL196344	Alpha-2C adrenergic receptor		 32								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167575&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44402352	104052791		CHEMBL196344				ZINC28525426	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50309012	COC(=O)CNC(=O)CNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC12	InChI=1S/C25H32N4O5/c1-34-22(32)12-26-21(31)11-27-25(33)23-17-10-19-24-16(15-4-2-3-5-18(15)28-24)8-9-29(19)13-14(17)6-7-20(23)30/h2-5,14,17,19-20,23,28,30H,6-13H2,1H3,(H,26,31)(H,27,33)/t14-,17?,19-,20-,23+/m0/s1	GJZPDXKFPWGUKH-SZBWEJNYSA-N	50167577	CHEMBL193458::{2-[((1R,2S,4aR,13bS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carbonyl)-amino]-acetylamino}-acetic acid methyl ester	Alpha-2C adrenergic receptor		 5.2								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167577&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44402531	104052793		CHEMBL193458				ZINC28524274	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50309013	CC(C)(C)OC(=O)NCCCNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC12	InChI=1S/C28H40N4O4/c1-28(2,3)36-27(35)30-13-6-12-29-26(34)24-20-15-22-25-19(18-7-4-5-8-21(18)31-25)11-14-32(22)16-17(20)9-10-23(24)33/h4-5,7-8,17,20,22-24,31,33H,6,9-16H2,1-3H3,(H,29,34)(H,30,35)/t17-,20?,22-,23-,24+/m0/s1	QKNLXLITLKKTTC-KOASTNMESA-N	50167579	CHEMBL196064::{3-[((1R,2S,4aR,13bS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carbonyl)-amino]-propyl}-carbamic acid tert-butyl ester	Alpha-2C adrenergic receptor		 2.8								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167579&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44402345	104052795		CHEMBL196064				ZINC28525605	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50309014	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC2[C@H]1C(=O)NCCCNC(=O)OCc1ccccc1	InChI=1S/C31H38N4O4/c36-27-12-11-21-18-35-16-13-23-22-9-4-5-10-25(22)34-29(23)26(35)17-24(21)28(27)30(37)32-14-6-15-33-31(38)39-19-20-7-2-1-3-8-20/h1-5,7-10,21,24,26-28,34,36H,6,11-19H2,(H,32,37)(H,33,38)/t21-,24?,26-,27-,28+/m0/s1	CDNZAOVICDKJNC-ZXLWIGOHSA-N	50167578	CHEMBL369938::{3-[((1R,2S,4aR,13bS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carbonyl)-amino]-propyl}-carbamic acid benzyl ester	Alpha-2C adrenergic receptor		 1.1								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167578	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167578&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44402346	104052794		CHEMBL369938				ZINC28525607	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50309015	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC2[C@H]1C(O)=O	InChI=1S/C20H24N2O3/c23-17-6-5-11-10-22-8-7-13-12-3-1-2-4-15(12)21-19(13)16(22)9-14(11)18(17)20(24)25/h1-4,11,14,16-18,21,23H,5-10H2,(H,24,25)/t11-,14?,16-,17-,18+/m0/s1	AADVZSXPNRLYLV-YYCJRWKUSA-N	50167581	(1R,2S,4aR,13bS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid::CHEMBL382310	Alpha-2C adrenergic receptor		 19								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167581	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167581&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44402344	104052797		CHEMBL382310				ZINC03947438	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50309016	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC2[C@H]1C(=O)NCCCC(O)=O	InChI=1S/C24H31N3O4/c28-20-8-7-14-13-27-11-9-16-15-4-1-2-5-18(15)26-23(16)19(27)12-17(14)22(20)24(31)25-10-3-6-21(29)30/h1-2,4-5,14,17,19-20,22,26,28H,3,6-13H2,(H,25,31)(H,29,30)/t14-,17?,19-,20-,22+/m0/s1	ILZUPWALMALDJM-ZMTQNQTKSA-N	50167580	4-[((1R,2S,4aR,13bS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carbonyl)-amino]-butyric acid::CHEMBL195925	Alpha-2C adrenergic receptor		 3								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167580&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44402583	104052796		CHEMBL195925				ZINC28525247	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50309017	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15?,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-YGRBPWIASA-N	50167576	(1R,2S,4aR,13bS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester::CHEMBL196400	Alpha-2C adrenergic receptor		 0.880000								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167576&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44402476	104052792	48565	CHEMBL196400				ZINC06145324	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50309018	COC(=O)CNC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC12	InChI=1S/C23H29N3O4/c1-30-20(28)11-24-23(29)21-16-10-18-22-15(14-4-2-3-5-17(14)25-22)8-9-26(18)12-13(16)6-7-19(21)27/h2-5,13,16,18-19,21,25,27H,6-12H2,1H3,(H,24,29)/t13-,16?,18-,19-,21+/m0/s1	JDERGZWWHCGMHD-NOSKHEOHSA-N	50167582	CHEMBL370005::[((1R,2S,4aR,13bS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carbonyl)-amino]-acetic acid methyl ester	Alpha-2C adrenergic receptor		 8								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167582	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167582&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44402579	104052798		CHEMBL370005				ZINC28525330	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50309019	O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3CC2[C@H]1C(=O)NCCCC(=O)OCc1ccccc1	InChI=1S/C31H37N3O4/c35-27-13-12-21-18-34-16-14-23-22-9-4-5-10-25(22)33-30(23)26(34)17-24(21)29(27)31(37)32-15-6-11-28(36)38-19-20-7-2-1-3-8-20/h1-5,7-10,21,24,26-27,29,33,35H,6,11-19H2,(H,32,37)/t21-,24?,26-,27-,29+/m0/s1	JZGCFEQRHXUOAB-BUCDTFABSA-N	50167573	4-[((1R,2S,4aR,13bS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carbonyl)-amino]-butyric acid benzyl ester::CHEMBL196451	Alpha-2C adrenergic receptor		 0.650000								ChEMBL	10.1016/j.bmcl.2005.03.116	10.7270/Q2KS6R23	15911252			Mustafa, SM; Bavadekar, SA; Ma, G; Moore, BM; Feller, DR; Miller, DD	University of Tennessee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167573&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11203101	104052789		CHEMBL196451				ZINC28525603	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50297275	COc1cc2CCN(C)C3Cc4cc5OCOc5cc4-c(c1OCc1ccc(Br)cc1)c23	InChI=1S/C26H24BrNO4/c1-28-8-7-16-10-23(29-2)26(30-13-15-3-5-18(27)6-4-15)25-19-12-22-21(31-14-32-22)11-17(19)9-20(28)24(16)25/h3-6,10-12,20H,7-9,13-14H2,1-2H3	AJIMVLSQIMXLNV-UHFFFAOYSA-N	50132341	CHEMBL3633757	Alpha-2C adrenergic receptor		>900								ChEMBL	10.1016/j.bmcl.2015.10.012	10.7270/Q2HD7XGH	26475518			Ponnala, S; Kapadia, N; Madapa, S; Alberts, IL; Harding, WW	City University of New York	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132341&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122195524	321903449		CHEMBL3633757					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300483	CN(C)C[C@H]1CC2[C@H](O1)c1cc(F)ccc1Oc1ccccc21	InChI=1S/C19H20FNO2/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19+/m1/s1	LGHLMADLDHUIJY-MQSINFNDSA-N	50162960	(11-Fluoro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL194659	Alpha-2C adrenergic receptor		 200								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162960	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162960&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401041	104049053		CHEMBL194659				ZINC28523021	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300487	Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21	InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H	YNPFMWCWRVTGKJ-UHFFFAOYSA-N	31005	2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine::MIANSERIN HYDROCHLORIDE::MLS000069681::SMR000058472::cid_68551	Alpha-2C adrenergic receptor		 3.8								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31005&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68551	242052839						ZINC00000504	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300497	CN(C)C[C@H]1CC2[C@H](O1)c1cc(Cl)ccc1Oc1ccccc21	InChI=1S/C19H20ClNO2/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19+/m1/s1	RHPCETHLGGFAQB-MQSINFNDSA-N	50162961	(11-Chloro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL435301	Alpha-2C adrenergic receptor		 26								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162961	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162961&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401243	104049054		CHEMBL435301				ZINC28521179	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300526	CN(C)C[C@H]1C[C@H]2[C@H](O1)c1cc(F)ccc1Sc1ccccc21	InChI=1S/C19H20FNOS/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15-,19+/m1/s1	BSOLCASXROXPRZ-MUKKUYKPSA-N	50162959	(11-Fluoro-2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL366164	Alpha-2C adrenergic receptor		 93								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162959	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162959&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11186523	104049052		CHEMBL366164					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300540	Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12	InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3	RAPZEAPATHNIPO-UHFFFAOYSA-N	50001885	(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone	Alpha-2C adrenergic receptor		 3.2								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	8NU	6A93,6CM4	5073	103916252	8871	CHEMBL85	DB00734	96		ZINC00538312	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300545	CN1CCN2C(C1)c1ccccc1Cc1cccnc21	InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3	RONZAEMNMFQXRA-UHFFFAOYSA-N	50115644	(+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::2-methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::CHEMBL654::MIRTAZAPINE::ORG 3770::REMERON	Alpha-2C adrenergic receptor		 18								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115644&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4205	104009532	6950	CHEMBL654	DB00370	7241	C07570	ZINC19702119	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300557	CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12	InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3	KVWDHTXUZHCGIO-UHFFFAOYSA-N	35254	2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine	Alpha-2C adrenergic receptor		 82								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4585	85753333	7735	CHEMBL715	DB00334	47	C07322	ZINC52957434	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300560	CN(C)C[C@@H]1CC2[C@H](O1)c1cc(F)ccc1Sc1ccccc21	InChI=1S/C19H20FNOS/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19-/m0/s1	BSOLCASXROXPRZ-SHZHJNINSA-N	50162964	(11-Fluoro-2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL363581	Alpha-2C adrenergic receptor		 78								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162964&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401106	104049057		CHEMBL363581				ZINC28523813	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300569	CN(C)C[C@H]1CC2[C@H](O1)c1cc(F)ccc1Sc1ccccc21	InChI=1S/C19H20FNOS/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19+/m1/s1	BSOLCASXROXPRZ-MQSINFNDSA-N	50162957	(11-Fluoro-2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL193639	Alpha-2C adrenergic receptor		 59								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162957&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401164	104049050		CHEMBL193639				ZINC28523621	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300584	CN(C)C[C@H]1CC2[C@H](O1)c1ccccc1Cc1ccccc21	InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16-,19?,20-/m1/s1	ACTVOFFLDWZANE-ZNCRQWOUSA-N	50162956	CHEMBL371352::Dimethyl-(11-methyl-3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-ylmethyl)-amine	Alpha-2C adrenergic receptor		 69								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162956	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162956&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401612	104049049		CHEMBL371352				ZINC26670194	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300586	CN(C)C[C@@H]1CC2[C@H](O1)c1cc(Cl)ccc1Oc1ccccc21	InChI=1S/C19H20ClNO2/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19-/m0/s1	RHPCETHLGGFAQB-SHZHJNINSA-N	50162965	(11-Chloro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL364270	Alpha-2C adrenergic receptor		 677								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162965	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162965&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401042	104049058		CHEMBL364270				ZINC13980700	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300606	CN(C)C[C@@H]1CC2[C@H](O1)c1cc(F)ccc1Oc1ccccc21	InChI=1S/C19H20FNO2/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19-/m0/s1	LGHLMADLDHUIJY-SHZHJNINSA-N	50162963	(11-Fluoro-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL195706	Alpha-2C adrenergic receptor		 219								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162963	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162963&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401194	104049056		CHEMBL195706				ZINC28523216	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300620	CN(C)C[C@H]1CC2[C@H](O1)c1cc(F)ccc1Sc1ccccc21	InChI=1S/C19H20FNOS/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19+/m1/s1	BSOLCASXROXPRZ-MQSINFNDSA-N	50162957	(11-Fluoro-2,3,3a,12b-tetrahydro-1-oxa-8-thia-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL193639	Alpha-2C adrenergic receptor		 59.0								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162957&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401164	104049050		CHEMBL193639				ZINC28523621	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300629	CN(C)C[C@H]1CC2[C@H](O1)c1cc(Br)ccc1Oc1ccccc21	InChI=1S/C19H20BrNO2/c1-21(2)11-13-10-15-14-5-3-4-6-17(14)23-18-8-7-12(20)9-16(18)19(15)22-13/h3-9,13,15,19H,10-11H2,1-2H3/t13-,15?,19+/m1/s1	FXHLGRYCQSRFHY-MQSINFNDSA-N	50162958	(11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine::CHEMBL193435	Alpha-2C adrenergic receptor		 742								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162958	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162958&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44401105	104049051		CHEMBL193435				ZINC28523812	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50300630	CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12	InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3	QZUDBNBUXVUHMW-UHFFFAOYSA-N	50001884	2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine	Alpha-2C adrenergic receptor		 2.9								ChEMBL	10.1021/jm049632c	10.7270/Q2MC8ZHB	15771415			Fernandez, J; Alonso, JM; Andres, JI; Cid, JM; Diaz, A; Iturrino, L; Gil, P; Megens, A; Sipido, VK; Trabanco, AA	Johnson & Johnson Pharmaceutical Research & Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2818	103916251	3766	CHEMBL42CHEMBL538973	DB00363	38	C06924	ZINC19796155	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50301917	COc1cccc2[C@H](CN(C)CCc3ccc4ccoc4c3)CCCc12	InChI=1S/C23H27NO2/c1-24(13-11-17-9-10-18-12-14-26-23(18)15-17)16-19-5-3-7-21-20(19)6-4-8-22(21)25-2/h4,6,8-10,12,14-15,19H,3,5,7,11,13,16H2,1-2H3/t19-/m0/s1	MHPMXTGKTXJIDI-IBGZPJMESA-N	50057128	(2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-amine::A-80426::CHEMBL268258	Alpha-2C adrenergic receptor		 2.1								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057128&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9928332	103953208		CHEMBL268258				ZINC03810797	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50310705	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2C adrenergic receptor		 0.500000								ChEMBL	10.1016/j.ejmech.2014.12.045	10.7270/Q2Q241XV	25557493			Kolaczkowski, M; Marcinkowska, M; Bucki, A; Sniecikowska, J; Pawlowski, M; Kazek, G; Siwek, A; Jastrzebska-Wiesek, M; Partyka, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P	Jagiellonian University Collegium Medicum	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50310706	NC(=O)c1ccccc1OCCCN1CCN(CC1)c1cccc2n(ccc12)S(=O)(=O)c1ccccc1	InChI=1S/C28H30N4O4S/c29-28(33)24-10-4-5-13-27(24)36-21-7-15-30-17-19-31(20-18-30)25-11-6-12-26-23(25)14-16-32(26)37(34,35)22-8-2-1-3-9-22/h1-6,8-14,16H,7,15,17-21H2,(H2,29,33)	KWZBJWOQFABHPF-UHFFFAOYSA-N	50070798	CHEMBL3409256	Alpha-2C adrenergic receptor		 190								ChEMBL	10.1016/j.ejmech.2014.12.045	10.7270/Q2Q241XV	25557493			Kolaczkowski, M; Marcinkowska, M; Bucki, A; Sniecikowska, J; Pawlowski, M; Kazek, G; Siwek, A; Jastrzebska-Wiesek, M; Partyka, A; Wasik, A; Wesolowska, A; Mierzejewski, P; Bienkowski, P	Jagiellonian University Collegium Medicum	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070798	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070798&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71151588	103964629		CHEMBL3409256				ZINC29463039	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50301994	Fc1ccc2CC(CC3CNC=N3)Cc2c1	InChI=1S/C13H15FN2/c14-12-2-1-10-3-9(4-11(10)6-12)5-13-7-15-8-16-13/h1-2,6,8-9,13H,3-5,7H2,(H,15,16)	HBMJQYDGBNSZMC-UHFFFAOYSA-N	50131357	4-(5-Fluoro-indan-2-ylmethyl)-4,5-dihydro-1H-imidazole::CHEMBL90997::S-34324	Alpha-2C adrenergic receptor		 19								ChEMBL	10.1021/jm049619s	10.7270/Q22F7MZC	15771448			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Fernandez, J; Font, LM; Hens, KA; Iturrino, L; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Vermote, PC; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131357&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10220053	104022541		CHEMBL90997				ZINC26652869	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50309697	Cl.Fc1cccc(CCCNCCc2ccnc(n2)-n2ccnc2)c1	InChI=1S/C18H20FN5.ClH/c19-16-5-1-3-15(13-16)4-2-8-20-9-6-17-7-10-22-18(23-17)24-12-11-21-14-24;/h1,3,5,7,10-14,20H,2,4,6,8-9H2;1H	ZFCKGWSPRRORFE-UHFFFAOYSA-N	50070042	CHEMBL3407810	Alpha-2C adrenergic receptor		 200								ChEMBL	10.1021/jm501719e	10.7270/Q2CR5W25	25489882			Mukherjee, P; Li, H; Sevrioukova, I; Chreifi, G; Martásek, P; Roman, LJ; Poulos, TL; Silverman, RB	Northwestern University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070042&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118730369	103963984		CHEMBL3407810				ZINC27307061	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50319914	Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1	InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)	MRBDMNSDAVCSSF-UHFFFAOYSA-N	31046	3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430	Alpha-2C adrenergic receptor		 80								ChEMBL	10.1016/j.bmcl.2005.07.083	10.7270/Q2D799ZF	16153828			Hong, SS; Bavadekar, SA; Lee, SI; Patil, PN; Lalchandani, SG; Feller, DR; Miller, DD	Chungbuk National University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			5775	252615298			DB00692			ZINC00020251	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50319919	COc1cccc(c1)N(N=C1NCCN1)c1ccc(C)cc1	InChI=1S/C17H20N4O/c1-13-6-8-14(9-7-13)21(20-17-18-10-11-19-17)15-4-3-5-16(12-15)22-2/h3-9,12H,10-11H2,1-2H3,(H2,18,19,20)	NEQHKSNFFVEGHN-UHFFFAOYSA-N	50173162	CHEMBL362954::N'-(4,5-Dihydro-1H-imidazol-2-yl)-N-(3-methoxy-phenyl)-N-p-tolyl-hydrazine	Alpha-2C adrenergic receptor		 3.8								ChEMBL	10.1016/j.bmcl.2005.07.083	10.7270/Q2D799ZF	16153828			Hong, SS; Bavadekar, SA; Lee, SI; Patil, PN; Lalchandani, SG; Feller, DR; Miller, DD	Chungbuk National University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173162	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173162&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11653915	104059133		CHEMBL362954				ZINC28526324	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50319924	Cc1ccc(cc1)N(N=C1NCCN1)c1cccc(O)c1	InChI=1S/C16H18N4O/c1-12-5-7-13(8-6-12)20(19-16-17-9-10-18-16)14-3-2-4-15(21)11-14/h2-8,11,21H,9-10H2,1H3,(H2,17,18,19)	ONSCHPQYHGOIQX-UHFFFAOYSA-N	50173164	3-[N'-(4,5-Dihydro-1H-imidazol-2-yl)-N-p-tolyl-hydrazino]-phenol::CHEMBL194849	Alpha-2C adrenergic receptor		 13								ChEMBL	10.1016/j.bmcl.2005.07.083	10.7270/Q2D799ZF	16153828			Hong, SS; Bavadekar, SA; Lee, SI; Patil, PN; Lalchandani, SG; Feller, DR; Miller, DD	Chungbuk National University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173164	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173164&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9883506	104059135		CHEMBL194849				ZINC28526325	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50319282	Cl.NC[C@H]1C[C@@H]1c1cc(F)ccc1OCC=C	InChI=1S/C13H16FNO.ClH/c1-2-5-16-13-4-3-10(14)7-12(13)11-6-9(11)8-15;/h2-4,7,9,11H,1,5-6,8,15H2;1H/t9-,11+;/m1./s1	MNIAWGCBQVLINM-XQKZEKTMSA-N	50076240	CHEMBL3416063	Alpha-2C adrenergic receptor		<1000								ChEMBL	10.1021/jm5019274	10.7270/Q2BC4181	25633969			Cheng, J; Giguère, PM; Onajole, OK; Lv, W; Gaisin, A; Gunosewoyo, H; Schmerberg, CM; Pogorelov, VM; Rodriguiz, RM; Vistoli, G; Wetsel, WC; Roth, BL; Kozikowski, AP	University of Illinois at Chicago	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076240&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			92042918	103969173		CHEMBL3416063				ZINC34800561	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50325976	C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)[C@@H]2C[C@H]12	InChI=1S/C19H25N3O2/c1-13-4-2-9-22(13)10-3-11-24-15-7-5-14(6-8-15)18-16-12-17(16)19(23)21-20-18/h5-8,13,16-17H,2-4,9-12H2,1H3,(H,21,23)/t13-,16+,17-/m1/s1	FJHKZEVPGYADEG-XOKHGSTOSA-N	50079576	CHEMBL3417585	Alpha-2C adrenergic receptor		 1500								ChEMBL	10.1016/j.ejmech.2015.03.054	10.7270/Q2C24Z4M	25827402			Hudkins, RL; Becknell, NC; Lyons, JA; Aimone, LD; Olsen, M; Haltiwanger, RC; Mathiasen, JR; Raddatz, R; Gruner, JA	Teva Global R & D.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079576&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118734875	313074049		CHEMBL3417585					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50325977	C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)[C@H]2C[C@@H]12	InChI=1S/C19H25N3O2/c1-13-4-2-9-22(13)10-3-11-24-15-7-5-14(6-8-15)18-16-12-17(16)19(23)21-20-18/h5-8,13,16-17H,2-4,9-12H2,1H3,(H,21,23)/t13-,16-,17+/m1/s1	FJHKZEVPGYADEG-XYPHTWIQSA-N	50079575	CHEMBL3417586	Alpha-2C adrenergic receptor		 1800								ChEMBL	10.1016/j.ejmech.2015.03.054	10.7270/Q2C24Z4M	25827402			Hudkins, RL; Becknell, NC; Lyons, JA; Aimone, LD; Olsen, M; Haltiwanger, RC; Mathiasen, JR; Raddatz, R; Gruner, JA	Teva Global R & D.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079575&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118734876	313074048		CHEMBL3417586					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50333902	C[C@@H](N)Cn1ncc2ccc(O)cc12	InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m1/s1	WBYHTZYHAFNBKW-SSDOTTSWSA-N	50180256	1-((R)-2-aminopropyl)-1H-indazol-6-ol::CHEMBL437314	Alpha-2C adrenergic receptor					 5660					ChEMBL	10.1021/jm050663x	10.7270/Q23B5ZQW	16392816			May, JA; Dantanarayana, AP; Zinke, PW; McLaughlin, MA; Sharif, NA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180256&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11500503	104065373		CHEMBL437314				ZINC13679044	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50333926	C[C@H](N)Cn1ncc2ccc(O)cc12	InChI=1S/C10H13N3O/c1-7(11)6-13-10-4-9(14)3-2-8(10)5-12-13/h2-5,7,14H,6,11H2,1H3/t7-/m0/s1	WBYHTZYHAFNBKW-ZETCQYMHSA-N	50180251	1-((S)-2-aminopropyl)-1H-indazol-6-ol::CHEMBL371300	Alpha-2C adrenergic receptor		 4700								ChEMBL	10.1021/jm050663x	10.7270/Q23B5ZQW	16392816			May, JA; Dantanarayana, AP; Zinke, PW; McLaughlin, MA; Sharif, NA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180251&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9834183	104065368		CHEMBL371300				ZINC00009096	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50337257	COc1cccc(c1)N1CCN(CCCCn2ncc(=O)n(C)c2=O)CC1	InChI=1S/C19H27N5O3/c1-21-18(25)15-20-24(19(21)26)9-4-3-8-22-10-12-23(13-11-22)16-6-5-7-17(14-16)27-2/h5-7,14-15H,3-4,8-13H2,1-2H3	PGGCRGAETLNAJC-UHFFFAOYSA-N	50182020	2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione::CHEMBL426317	Alpha-2C adrenergic receptor		 109								ChEMBL	10.1016/j.bmcl.2006.01.052	10.7270/Q2ZC82FS	16458504			Prabhakaran, J; Parsey, RV; Majo, VJ; Hsiung, SC; Milak, MS; Tamir, H; Simpson, NR; Van Heertum, RL; Mann, JJ; Dileep Kumar, JS	Columbia University College of Physicians and Surgeons	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182020	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182020&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11948707	104066846		CHEMBL426317				ZINC34801069	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50343679	OC1(CC2CCC(C1)N2CCCC(=O)c1ccc(F)cc1)c1ccc(Cl)cc1	InChI=1S/C23H25ClFNO2/c24-18-7-5-17(6-8-18)23(28)14-20-11-12-21(15-23)26(20)13-1-2-22(27)16-3-9-19(25)10-4-16/h3-10,20-21,28H,1-2,11-15H2	CXQUOFVDYCOSEZ-UHFFFAOYSA-N	50185473	4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2.1]octan-8-yl)-1-(4-fluorophenyl)butan-1-one::4-[3-(4-Chloro-phenyl)-3-hydroxy-8-aza-bicyclo[3.2.1]oct-8-yl]-1-(4-fluoro-phenyl)-butan-1-one::4-[3-(4-Chlorophenyl)-3-hydroxy-8-azabicyclo[3.2.1]oct-8-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL210578	Alpha-2C adrenergic receptor		 143								ChEMBL	10.1016/j.bmcl.2006.03.057	10.7270/Q2571BM5	16621538			Ablordeppey, SY; Lyles-Eggleston, M; Bricker, B; Zhang, W; Zhu, X; Goodman, C; Roth, BL	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185473&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			13091268	104069684		CHEMBL210578				ZINC12356279	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50343688	OC1(CCN(CCCC(=O)c2ccc(F)cc2)C1)c1ccc(Cl)cc1	InChI=1S/C20H21ClFNO2/c21-17-7-5-16(6-8-17)20(25)11-13-23(14-20)12-1-2-19(24)15-3-9-18(22)10-4-15/h3-10,25H,1-2,11-14H2	BETHXCLHMRGYBW-UHFFFAOYSA-N	50185474	(+)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::(-)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(-)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::4-[3-(4-Chloro-phenyl)-3-hydroxy-pyrrolidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one::4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::CHEMBL150161	Alpha-2C adrenergic receptor		 94								ChEMBL	10.1016/j.bmcl.2006.03.057	10.7270/Q2571BM5	16621538			Ablordeppey, SY; Lyles-Eggleston, M; Bricker, B; Zhang, W; Zhu, X; Goodman, C; Roth, BL	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185474&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9906978	104069685		CHEMBL150161				ZINC12356157	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50333296	COc1ccc2cccc(N3CCN(CCCCn4ncc(=O)n(C)c4=O)CC3)c2c1	InChI=1S/C23H29N5O3/c1-25-22(29)17-24-28(23(25)30)11-4-3-10-26-12-14-27(15-13-26)21-7-5-6-18-8-9-19(31-2)16-20(18)21/h5-9,16-17H,3-4,10-15H2,1-2H3	GKTQBPYMIGXPKG-UHFFFAOYSA-N	50180054	CHEMBL199824::[O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione	Alpha-2C adrenergic receptor		 24								ChEMBL	10.1021/jm050725j	10.7270/Q2R49QBD	16392798			Kumar, JS; Majo, VJ; Hsiung, SC; Millak, MS; Liu, KP; Tamir, H; Prabhakaran, J; Simpson, NR; Van Heertum, RL; Mann, JJ; Parsey, RV	Columbia University College of Physicians and Surgeons	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180054&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10324985	104065192		CHEMBL199824				ZINC03825965	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50345133	COc1cc-2c(C[C@@H]3N(C)CCc4cc(OC)c(OC)c-2c34)cc1O	InChI=1S/C20H23NO4/c1-21-6-5-11-9-17(24-3)20(25-4)19-13-10-16(23-2)15(22)8-12(13)7-14(21)18(11)19/h8-10,14,22H,5-7H2,1-4H3/t14-/m0/s1	ZFLRVRLYWHNAEC-AWEZNQCLSA-N	50250422	(+)-N-methyl-laurotetanine::CHEMBL464099::N-methyllaurotetanine	Alpha-2C adrenergic receptor		>950								ChEMBL	10.1021/np500893h	10.7270/Q23B61WB	25695425			Madapa, S; Harding, WW	City University of New York	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50250422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50250422&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16573	104104200		CHEMBL464099				ZINC00338123	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363410	CCNCC(=O)N1CCn2cccc2C1c1cccc(Cl)c1	InChI=1S/C34H47FN6O4S/c1-4-5-6-7-8-9-10-11-12-13-18-39(3)31(43)24-41-22-28(19-27-20-37-33(45)40(21-27)23-30(42)36-2)32(44)38-34(41)46-25-26-14-16-29(35)17-15-26/h14-17,20-22H,4-13,18-19,23-25H2,1-3H3,(H,36,42)	FNLKETQXRMMFDO-UHFFFAOYSA-N	50097718	CHEMBL3588906	Alpha-2C adrenergic receptor					<501187					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097718&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46743614	103994895		CHEMBL3588906				ZINC37858510	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362059	CCN(CC)CCNc1ccc(Nc2c(CC)c(C)nc3c(C)cccc23)cc1	InChI=1S/C25H34N4/c1-6-22-19(5)27-24-18(4)10-9-11-23(24)25(22)28-21-14-12-20(13-15-21)26-16-17-29(7-2)8-3/h9-15,26H,6-8,16-17H2,1-5H3,(H,27,28)	VWHNYSUZLOHFTG-UHFFFAOYSA-N	50196106	CHEMBL216197::N-(2-diethylaminoethyl)-N'-(3-ethyl-2,8-dimethylquinolin-4-yl)benzene-1,4-diamine	Alpha-2C adrenergic receptor		 82								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196106&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090627	104077982		CHEMBL216197				ZINC34801115	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362060	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)cnc3ccc(F)cc23)cc1	InChI=1S/C23H27FN4O/c1-23(2)15-28(11-10-27(23)3)19-7-5-18(6-8-19)26-22-16(14-29)13-25-21-9-4-17(24)12-20(21)22/h4-9,12-13,29H,10-11,14-15H2,1-3H3,(H,25,26)	KJGIXOOWJYEMMO-UHFFFAOYSA-N	50196108	CHEMBL424917::{6-fluoro-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 50								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196108&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10475736	104077984		CHEMBL424917				ZINC34801088	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362066	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)cnc3ccccc23)cc1	InChI=1S/C23H28N4O/c1-23(2)16-27(13-12-26(23)3)19-10-8-18(9-11-19)25-22-17(15-28)14-24-21-7-5-4-6-20(21)22/h4-11,14,28H,12-13,15-16H2,1-3H3,(H,24,25)	SASCGBIFSTWAKB-UHFFFAOYSA-N	50196118	CHEMBL268217::{4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 6.4								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196118&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10474679	104077994		CHEMBL268217				ZINC34801106	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362067	CC(O)c1c(C)nc2ccccc2c1Nc1ccc(cc1)N1CCN(C)C(C)C1	InChI=1S/C24H30N4O/c1-16-15-28(14-13-27(16)4)20-11-9-19(10-12-20)26-24-21-7-5-6-8-22(21)25-17(2)23(24)18(3)29/h5-12,16,18,29H,13-15H2,1-4H3,(H,25,26)	VIFJNFUXJIBEDW-UHFFFAOYSA-N	50196117	1-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-2-methylquinolin-3-yl}ethanol::CHEMBL217253	Alpha-2C adrenergic receptor		 4.9								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196117&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090631	104077993		CHEMBL217253				ZINC52962008	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362070	Cc1nc2ccccc2c(Nc2ccc(NCCN3CCCC3)cc2)c1C	InChI=1S/C23H28N4/c1-17-18(2)25-22-8-4-3-7-21(22)23(17)26-20-11-9-19(10-12-20)24-13-16-27-14-5-6-15-27/h3-4,7-12,24H,5-6,13-16H2,1-2H3,(H,25,26)	QBONYGHVEVRMDD-UHFFFAOYSA-N	50196114	CHEMBL440594::N-(2,3-dimethylquinolin-4-yl)-N'-(2-pyrrolidin-1-ylethyl)benzene-1,4-diamine	Alpha-2C adrenergic receptor		 100								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196114&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090600	104077990		CHEMBL440594				ZINC34801093	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362084	C[C@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)c(C)ccc23)cc1	InChI=1S/C25H32N4/c1-16-7-12-23-24(18(16)3)26-20(5)19(4)25(23)27-21-8-10-22(11-9-21)29-14-13-28(6)17(2)15-29/h7-12,17H,13-15H2,1-6H3,(H,26,27)/t17-/m0/s1	OFZVRVWUVPCFQQ-KRWDZBQOSA-N	50196124	(S)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine::CHEMBL216674	Alpha-2C adrenergic receptor		 84								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196124&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090594	104078000		CHEMBL216674				ZINC52961971	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362086	CN1CCN(CC1)c1ccc(Nc2c(Cc3ccccc3)c(C)nc3ccccc23)cc1	InChI=1S/C28H30N4/c1-21-26(20-22-8-4-3-5-9-22)28(25-10-6-7-11-27(25)29-21)30-23-12-14-24(15-13-23)32-18-16-31(2)17-19-32/h3-15H,16-20H2,1-2H3,(H,29,30)	CNOXIXMPZLKURQ-UHFFFAOYSA-N	50196128	(3-benzyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine::CHEMBL384925	Alpha-2C adrenergic receptor		 35								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196128&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090621	104078004		CHEMBL384925				ZINC53173678	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362087	CC1CN(CCN1C)c1ccc(Nc2c(CO)c(C)nc3ccccc23)cc1	InChI=1S/C23H28N4O/c1-16-14-27(13-12-26(16)3)19-10-8-18(9-11-19)25-23-20-6-4-5-7-22(20)24-17(2)21(23)15-28/h4-11,16,28H,12-15H2,1-3H3,(H,24,25)	BSEZBDDBKUJHQP-UHFFFAOYSA-N	50196129	CHEMBL214996::{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-2-methylquinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 7.5								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196129&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10045088	104078005		CHEMBL214996				ZINC52961856	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362089	CN1CCCN(C1)c1ccc(Nc2c(C)c(C)nc3c(C)cccc23)cc1	InChI=1S/C23H28N4/c1-16-7-5-8-21-22(16)24-18(3)17(2)23(21)25-19-9-11-20(12-10-19)27-14-6-13-26(4)15-27/h5,7-12H,6,13-15H2,1-4H3,(H,24,25)	KUMLVCNUFRRWHR-UHFFFAOYSA-N	50196111	4-(3-methyltetrahydropyrimidin-1(2H)-yl)phenyl]-(2,3,8-trimethylquinolin-4-yl)amine::CHEMBL216072	Alpha-2C adrenergic receptor		 770								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196111&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090599	104077987		CHEMBL216072				ZINC34801117	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362092	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)c(C)ccc23)cc1	InChI=1S/C25H32N4/c1-16-7-12-23-24(18(16)3)26-20(5)19(4)25(23)27-21-8-10-22(11-9-21)29-14-13-28(6)17(2)15-29/h7-12,17H,13-15H2,1-6H3,(H,26,27)	OFZVRVWUVPCFQQ-UHFFFAOYSA-N	50196132	CHEMBL217203::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 5								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196132	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196132&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10362866	104078008		CHEMBL217203				ZINC52961985	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362098	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)ccc(C)c23)cc1	InChI=1S/C25H32N4/c1-16-7-8-17(2)24-23(16)25(19(4)20(5)26-24)27-21-9-11-22(12-10-21)29-14-13-28(6)18(3)15-29/h7-12,18H,13-15H2,1-6H3,(H,26,27)	KTKKHYOEEDBCLW-UHFFFAOYSA-N	50196112	CHEMBL384318::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,5,8-tetramethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 390								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196112&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090597	104077988		CHEMBL384318				ZINC53173617	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362099	C[C@@H]1CN(CCN1)c1ccc(Nc2c(CO)cnc3ccccc23)cc1	InChI=1S/C21H24N4O/c1-15-13-25(11-10-22-15)18-8-6-17(7-9-18)24-21-16(14-26)12-23-20-5-3-2-4-19(20)21/h2-9,12,15,22,26H,10-11,13-14H2,1H3,(H,23,24)/t15-/m1/s1	MDMIXTNJRVJFQM-OAHLLOKOSA-N	50196134	(R)-{4-[4-(3-methylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol::CHEMBL385722	Alpha-2C adrenergic receptor		 205								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196134	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196134&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090632	104078010		CHEMBL385722				ZINC53173570	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362105	C[C@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)ccc23)cc1	InChI=1S/C24H30N4/c1-16-6-11-22-23(14-16)25-19(4)18(3)24(22)26-20-7-9-21(10-8-20)28-13-12-27(5)17(2)15-28/h6-11,14,17H,12-13,15H2,1-5H3,(H,25,26)/t17-/m0/s1	LKVQAMHRWJYSED-KRWDZBQOSA-N	50196140	(S)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7-trimethylquinolin-4-yl)amine::CHEMBL217278	Alpha-2C adrenergic receptor		 76								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196140&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090624	104078016		CHEMBL217278				ZINC52962028	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362107	CC1CN(CCN1C)c1ccc(Nc2c(CO)cnc3ccc(F)cc23)cc1	InChI=1S/C22H25FN4O/c1-15-13-27(10-9-26(15)2)19-6-4-18(5-7-19)25-22-16(14-28)12-24-21-8-3-17(23)11-20(21)22/h3-8,11-12,15,28H,9-10,13-14H2,1-2H3,(H,24,25)	RLNXYUWOYNTOTQ-UHFFFAOYSA-N	50196115	CHEMBL276417::{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-6-fluoroquinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 43								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196115&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10317643	104077991		CHEMBL276417				ZINC53059380	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362110	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)c(C)nc3ccccc23)cc1	InChI=1S/C24H30N4O/c1-17-21(15-29)23(20-7-5-6-8-22(20)25-17)26-18-9-11-19(12-10-18)28-14-13-27(4)24(2,3)16-28/h5-12,29H,13-16H2,1-4H3,(H,25,26)	AANVRTGJCGRJSR-UHFFFAOYSA-N	50196123	CHEMBL218675::{2-methyl-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 3.8								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196123&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090630	104077999		CHEMBL218675				ZINC34801107	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362117	CCN1CCN(CC1)c1ccc(Nc2c3ccccc3nc3ccccc23)cc1	InChI=1S/C25H26N4/c1-2-28-15-17-29(18-16-28)20-13-11-19(12-14-20)26-25-21-7-3-5-9-23(21)27-24-10-6-4-8-22(24)25/h3-14H,2,15-18H2,1H3,(H,26,27)	CUVBGWMAORETGV-UHFFFAOYSA-N	50196122	CHEMBL217366::GNF-PF-3878::N-(4-(4-ethylpiperazin-1-yl)phenyl)acridin-9-amine::TCMDC-124255	Alpha-2C adrenergic receptor		 37								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196122&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3072540	104077998		CHEMBL217366				ZINC52962012	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362119	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3ccc(F)cc23)cc1	InChI=1S/C23H27FN4/c1-15-14-28(12-11-27(15)4)20-8-6-19(7-9-20)26-23-16(2)17(3)25-22-10-5-18(24)13-21(22)23/h5-10,13,15H,11-12,14H2,1-4H3,(H,25,26)	OGGREUDUNWRXNK-UHFFFAOYSA-N	50196120	CHEMBL216727::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(6-fluoro-2,3-dimethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 16								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196120&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090626	104077996		CHEMBL216727				ZINC52961958	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362120	CC1CN(CCN1C)c1ccc(Nc2c(C)cnc3ccccc23)cc1	InChI=1S/C22H26N4/c1-16-14-23-21-7-5-4-6-20(21)22(16)24-18-8-10-19(11-9-18)26-13-12-25(3)17(2)15-26/h4-11,14,17H,12-13,15H2,1-3H3,(H,23,24)	TVLLCWBBMXDYLI-UHFFFAOYSA-N	50196131	CHEMBL217202::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(3-methylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 8.5								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196131	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196131&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090622	104078007		CHEMBL217202				ZINC52962005	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362126	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)c(C)ccc23)cc1	InChI=1S/C25H32N4/c1-16-7-12-23-24(18(16)3)26-20(5)19(4)25(23)27-21-8-10-22(11-9-21)29-14-13-28(6)17(2)15-29/h7-12,17H,13-15H2,1-6H3,(H,26,27)/t17-/m1/s1	OFZVRVWUVPCFQQ-QGZVFWFLSA-N	50196145	(R)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine::CHEMBL217567	Alpha-2C adrenergic receptor		 7.7								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196145	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196145&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090623	104078021		CHEMBL217567					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362130	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(C)c(CO)nc3ccccc23)cc1	InChI=1S/C23H28N4O/c1-16-14-27(13-12-26(16)3)19-10-8-18(9-11-19)24-23-17(2)22(15-28)25-21-7-5-4-6-20(21)23/h4-11,16,28H,12-15H2,1-3H3,(H,24,25)/t16-/m1/s1	CWSVSBNTQJZFGE-MRXNPFEDSA-N	50196126	(R)-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-3-methylquinolin-2-yl}methanol::CHEMBL217254	Alpha-2C adrenergic receptor		 9								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196126&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090601	104078002		CHEMBL217254				ZINC52962010	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362131	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)cccc23)cc1	InChI=1S/C24H30N4/c1-16-7-6-8-22-23(16)25-19(4)18(3)24(22)26-20-9-11-21(12-10-20)28-14-13-27(5)17(2)15-28/h6-12,17H,13-15H2,1-5H3,(H,25,26)	ONMSNZLMBSAGLW-UHFFFAOYSA-N	50196146	CHEMBL217177::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,8-trimethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 6.9								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196146&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090596	104078022		CHEMBL217177				ZINC52961981	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362132	Cc1nc2ccccc2c(Nc2ccc(cc2)N2CCN3CCCCC3C2)c1C	InChI=1S/C25H30N4/c1-18-19(2)26-24-9-4-3-8-23(24)25(18)27-20-10-12-21(13-11-20)29-16-15-28-14-6-5-7-22(28)17-29/h3-4,8-13,22H,5-7,14-17H2,1-2H3,(H,26,27)	MZAWJNSMQVUPQW-UHFFFAOYSA-N	50196109	(2,3-dimethylquinolin-4-yl)-[4-(octahydro-2H-pyrido[1,2-a]-pyrazin-2-yl)phenyl]amine::CHEMBL425983	Alpha-2C adrenergic receptor		 2.3								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196109&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10045713	104077985		CHEMBL425983				ZINC53255553	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362137	CCc1c(C)nc2c(C)cccc2c1Nc1ccc(cc1)N1CCCN(C)CC1	InChI=1S/C25H32N4/c1-5-22-19(3)26-24-18(2)8-6-9-23(24)25(22)27-20-10-12-21(13-11-20)29-15-7-14-28(4)16-17-29/h6,8-13H,5,7,14-17H2,1-4H3,(H,26,27)	HWDFFRKTRBIVTK-UHFFFAOYSA-N	50196147	(3-ethyl-2,8-dimethylquinolin-4-yl)-[4-(4-methyl-[1,4]diazepan-1-yl)phenyl]amine::CHEMBL386169	Alpha-2C adrenergic receptor		 8.5								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196147&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090628	104078023		CHEMBL386169				ZINC34801087	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362141	CN1CCN(CC1)c1ccc(Nc2c(c(C)nc3ccccc23)-c2ccccc2)cc1	InChI=1S/C27H28N4/c1-20-26(21-8-4-3-5-9-21)27(24-10-6-7-11-25(24)28-20)29-22-12-14-23(15-13-22)31-18-16-30(2)17-19-31/h3-15H,16-19H2,1-2H3,(H,28,29)	YRMKSXYNMSJIBT-UHFFFAOYSA-N	50196130	(2-methyl-3-phenylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine::CHEMBL216290	Alpha-2C adrenergic receptor		 35								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196130&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10319299	104078006		CHEMBL216290				ZINC52961950	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362142	CCc1c(C)nc2ccccc2c1Nc1ccc(cc1)N1CCN(C)CC1	InChI=1S/C23H28N4/c1-4-20-17(2)24-22-8-6-5-7-21(22)23(20)25-18-9-11-19(12-10-18)27-15-13-26(3)14-16-27/h5-12H,4,13-16H2,1-3H3,(H,24,25)	YEGLCEJPSSYEQE-UHFFFAOYSA-N	50196136	(3-ethyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine::CHEMBL425803	Alpha-2C adrenergic receptor		 25								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196136&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10109188	104078012		CHEMBL425803				ZINC53228274	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362147	CN1CCN(CC1)c1ccc(Nc2ccnc3ccccc23)cc1	InChI=1S/C20H22N4/c1-23-12-14-24(15-13-23)17-8-6-16(7-9-17)22-20-10-11-21-19-5-3-2-4-18(19)20/h2-11H,12-15H2,1H3,(H,21,22)	RXXDJBWYJTWSKV-UHFFFAOYSA-N	50196110	CHEMBL217665::GNF-PF-2857::N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::[4-(4-methylpiperazin-1-yl)phenyl]quinolin-4-ylamine	Alpha-2C adrenergic receptor		 1700								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196110&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4567175	104077986		CHEMBL217665				ZINC52962019	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362148	CN1CCN(CC1)c1ccc(Nc2c(C)cncc2C)cc1	InChI=1S/C18H24N4/c1-14-12-19-13-15(2)18(14)20-16-4-6-17(7-5-16)22-10-8-21(3)9-11-22/h4-7,12-13H,8-11H2,1-3H3,(H,19,20)	BDODJZYHQXXMMX-UHFFFAOYSA-N	50196133	(3,5-dimethyl-pyridin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl]amine::CHEMBL217180	Alpha-2C adrenergic receptor		>5000								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196133	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196133&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090634	104078009		CHEMBL217180				ZINC52634508	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362149	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cccc(Cl)c23)cc1	InChI=1S/C23H27ClN4/c1-15-14-28(13-12-27(15)4)19-10-8-18(9-11-19)26-23-16(2)17(3)25-21-7-5-6-20(24)22(21)23/h5-11,15H,12-14H2,1-4H3,(H,25,26)	DZQRMYQZZBIVHO-UHFFFAOYSA-N	50196138	(5-chloro-2,3-dimethylquinolin-4-yl)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]amine::CHEMBL217568	Alpha-2C adrenergic receptor		 135								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196138&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090598	104078014		CHEMBL217568				ZINC52961987	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362153	CN1CCN(CC1)c1ccc(Nc2c3ccccc3nc3ccccc23)cc1	InChI=1S/C24H24N4/c1-27-14-16-28(17-15-27)19-12-10-18(11-13-19)25-24-20-6-2-4-8-22(20)26-23-9-5-3-7-21(23)24/h2-13H,14-17H2,1H3,(H,25,26)	QZKGUNQLVFEEBA-UHFFFAOYSA-N	50196135	Acridin-9-yl-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine::CHEMBL106525::GNF-Pf-3427::N-(4-(4-methylpiperazin-1-yl)phenyl)acridin-9-amine::TCMDC-123912	Alpha-2C adrenergic receptor		 28								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196135	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196135&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			540335	104078011		CHEMBL106525		3930		ZINC53151259	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362159	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)cnc3cc(Cl)ccc23)cc1	InChI=1S/C23H27ClN4O/c1-23(2)15-28(11-10-27(23)3)19-7-5-18(6-8-19)26-22-16(14-29)13-25-21-12-17(24)4-9-20(21)22/h4-9,12-13,29H,10-11,14-15H2,1-3H3,(H,25,26)	LCLUBKMUZSVUCV-UHFFFAOYSA-N	50196107	CHEMBL216464::{7-chloro-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 5.9								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196107&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10251036	104077983		CHEMBL216464				ZINC34801089	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362162	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)cc(C)c23)cc1	InChI=1S/C25H32N4/c1-16-13-17(2)24-23(14-16)26-20(5)19(4)25(24)27-21-7-9-22(10-8-21)29-12-11-28(6)18(3)15-29/h7-10,13-14,18H,11-12,15H2,1-6H3,(H,26,27)	ISQPPFGYKGDIHL-UHFFFAOYSA-N	50196148	CHEMBL218730::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,5,7-tetramethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 132								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196148&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11741010	104078024		CHEMBL218730				ZINC52971517	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362163	CN1CCN(CC1(C)C)c1ccc(Nc2c(C)cnc3ccccc23)cc1	InChI=1S/C23H28N4/c1-17-15-24-21-8-6-5-7-20(21)22(17)25-18-9-11-19(12-10-18)27-14-13-26(4)23(2,3)16-27/h5-12,15H,13-14,16H2,1-4H3,(H,24,25)	RXEIREHXCVZQFP-UHFFFAOYSA-N	50196139	(3-methylquinolin-4-yl)-[4-(3,3,4-trimethylpiperazin-1-yl)phenyl]amine::CHEMBL218679	Alpha-2C adrenergic receptor		 5.4								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196139&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10473701	104078015		CHEMBL218679				ZINC34801110	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362165	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)ccc23)cc1	InChI=1S/C24H30N4/c1-16-6-11-22-23(14-16)25-19(4)18(3)24(22)26-20-7-9-21(10-8-20)28-13-12-27(5)17(2)15-28/h6-11,14,17H,12-13,15H2,1-5H3,(H,25,26)/t17-/m1/s1	LKVQAMHRWJYSED-QGZVFWFLSA-N	50196125	(R)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7-trimethylquinolin-4-yl)amine::CHEMBL383978	Alpha-2C adrenergic receptor		 8.3								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196125&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090595	104078001		CHEMBL383978					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362166	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)ccc23)cc1	InChI=1S/C24H30N4/c1-16-6-11-22-23(14-16)25-19(4)18(3)24(22)26-20-7-9-21(10-8-20)28-13-12-27(5)17(2)15-28/h6-11,14,17H,12-13,15H2,1-5H3,(H,25,26)	LKVQAMHRWJYSED-UHFFFAOYSA-N	50196113	CHEMBL262901::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7-trimethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 15								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196113&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10044968	104077989		CHEMBL262901				ZINC53033641	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362168	CN1CCN(CC1)c1ccc(Nc2c(C)c(C)nc3ccccc23)cc1	InChI=1S/C22H26N4/c1-16-17(2)23-21-7-5-4-6-20(21)22(16)24-18-8-10-19(11-9-18)26-14-12-25(3)13-15-26/h4-11H,12-15H2,1-3H3,(H,23,24)	YAPCYKZPQAMZQI-UHFFFAOYSA-N	50196141	(2,3-dimethylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl] amine::CHEMBL267464	Alpha-2C adrenergic receptor		 35								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196141&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10132386	104078017		CHEMBL267464				ZINC53050145	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362169	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(CO)cnc3ccc(F)cc23)cc1	InChI=1S/C22H25FN4O/c1-15-13-27(10-9-26(15)2)19-6-4-18(5-7-19)25-22-16(14-28)12-24-21-8-3-17(23)11-20(21)22/h3-8,11-12,15,28H,9-10,13-14H2,1-2H3,(H,24,25)/t15-/m1/s1	RLNXYUWOYNTOTQ-OAHLLOKOSA-N	50196127	(R)-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-6-fluoroquinolin-3-yl}methanol::CHEMBL214661	Alpha-2C adrenergic receptor		 38								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196127	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196127&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090633	104078003		CHEMBL214661					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362171	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(CO)cnc3ccccc23)cc1	InChI=1S/C22H26N4O/c1-16-14-26(12-11-25(16)2)19-9-7-18(8-10-19)24-22-17(15-27)13-23-21-6-4-3-5-20(21)22/h3-10,13,16,27H,11-12,14-15H2,1-2H3,(H,23,24)/t16-/m1/s1	FYGUXILZNQKUCD-MRXNPFEDSA-N	50196116	(R)-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol::CHEMBL217542	Alpha-2C adrenergic receptor		 9.2								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196116&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090602	104077992		CHEMBL217542				ZINC13977226	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362173	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cccc(C)c23)cc1	InChI=1S/C24H30N4/c1-16-7-6-8-22-23(16)24(18(3)19(4)25-22)26-20-9-11-21(12-10-20)28-14-13-27(5)17(2)15-28/h6-12,17H,13-15H2,1-5H3,(H,25,26)	JLEBPSNYUGYMNN-UHFFFAOYSA-N	50196121	CHEMBL217452::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,5-trimethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 87								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196121&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090625	104077997		CHEMBL217452				ZINC52962030	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362174	CC(C)c1c(C)nc2ccccc2c1Nc1ccc(cc1)N1CCN(C)CC1	InChI=1S/C24H30N4/c1-17(2)23-18(3)25-22-8-6-5-7-21(22)24(23)26-19-9-11-20(12-10-19)28-15-13-27(4)14-16-28/h5-12,17H,13-16H2,1-4H3,(H,25,26)	JLIOUCZCOQHOPO-UHFFFAOYSA-N	50196119	(3-isopropyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl]amine::CHEMBL425622	Alpha-2C adrenergic receptor		 52								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196119&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10177445	104077995		CHEMBL425622				ZINC53255565	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362175	CCc1c(C)nc2CCCCc2c1Nc1ccc(cc1)N1CCN(C)C(C)C1	InChI=1S/C24H34N4/c1-5-21-18(3)25-23-9-7-6-8-22(23)24(21)26-19-10-12-20(13-11-19)28-15-14-27(4)17(2)16-28/h10-13,17H,5-9,14-16H2,1-4H3,(H,25,26)	AWRXNUNJSQSZSP-UHFFFAOYSA-N	50196143	4-(3,4-dimethylpiperazin-1-yl)phenyl]-(3-ethyl-2-methyl-5,6,7,8-tetrahydroquinolin-4-yl)amine::CHEMBL217768	Alpha-2C adrenergic receptor		 110								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196143	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196143&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090635	104078019		CHEMBL217768				ZINC52962006	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362176	CC1CN(CCN1C)c1ccc(Nc2c(c(C)nc3ccccc23)-c2ccccc2)cc1	InChI=1S/C28H30N4/c1-20-19-32(18-17-31(20)3)24-15-13-23(14-16-24)30-28-25-11-7-8-12-26(25)29-21(2)27(28)22-9-5-4-6-10-22/h4-16,20H,17-19H2,1-3H3,(H,29,30)	IJXRJXMYHWPNMW-UHFFFAOYSA-N	50196142	CHEMBL218457::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2-methyl-3-phenylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 5								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196142	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196142&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10070896	104078018		CHEMBL218457				ZINC13977224	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50362185	CN1CCN(CC1)c1ccc(Nc2cc(C)nc3ccccc23)cc1	InChI=1S/C21H24N4/c1-16-15-21(19-5-3-4-6-20(19)22-16)23-17-7-9-18(10-8-17)25-13-11-24(2)12-14-25/h3-10,15H,11-14H2,1-2H3,(H,22,23)	MKIZKMFJTXEUHC-UHFFFAOYSA-N	50196137	CHEMBL216399::[4-(4-methylpiperazin-1-yl)phenyl]-(2-methylquinolin-4-yl)-amine	Alpha-2C adrenergic receptor		 690								ChEMBL	10.1021/jm060262x	10.7270/Q2RB747B	17034141			Hoglund, IP; Silver, S; Engstrom, MT; Salo, H; Tauber, A; Kyyronen, HK; Saarenketo, P; Hoffren, AM; Kokko, K; Pohjanoksa, K; Sallinen, J; Savola, JM; Wurster, S; Kallatsa, OA	Juvantia Pharma Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196137&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9923679	104078013		CHEMBL216399				ZINC52961945	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363325	Brc1cccc(Cn2ccnc2)c1	InChI=1S/C10H9BrN2/c11-10-3-1-2-9(6-10)7-13-5-4-12-8-13/h1-6,8H,7H2	BGYZLOIBJCHCTI-UHFFFAOYSA-N	50307216	1-(3-Bromobenzyl)-1H-imidazole::CHEMBL598391	Alpha-2C adrenergic receptor		 1175								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50307216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50307216&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10220337	104161577		CHEMBL598391				ZINC12370275	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363326	C(Nc1ccccc1-c1cccnc1)c1ccncc1	InChI=1S/C31H42FN5O3S/c1-3-4-5-6-7-8-9-10-11-12-17-36(2)28(38)22-37-21-26(18-25-19-33-30(40)34-20-25)29(39)35-31(37)41-23-24-13-15-27(32)16-14-24/h13-16,19-21H,3-12,17-18,22-23H2,1-2H3,(H,33,34,40)	LPFVTHQVZUGCCO-UHFFFAOYSA-N	50097707	CHEMBL3588904	Alpha-2C adrenergic receptor		 1072								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097707&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122180567	103994884		CHEMBL3588904				ZINC36286560	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363327	NCCSc1nc2ccccc2o1	InChI=1S/C9H10N2OS/c10-5-6-13-9-11-7-3-1-2-4-8(7)12-9/h1-4H,5-6,10H2	LIZDKHZOMRDDRY-UHFFFAOYSA-N	50421231	CHEMBL2087646	Alpha-2C adrenergic receptor		 646								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421231	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421231&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			434526	163370255		CHEMBL2087646				ZINC06584354	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363331	Cc1ccccc1NCc1ccncc1	InChI=1S/C27H34FN5O3S/c1-3-4-5-6-7-8-13-32(2)24(34)18-33-17-22(14-21-15-29-26(36)30-16-21)25(35)31-27(33)37-19-20-9-11-23(28)12-10-20/h9-12,15-17H,3-8,13-14,18-19H2,1-2H3,(H,29,30,36)	QCDCEUHORMYOQN-UHFFFAOYSA-N	50097708	CHEMBL3588903	Alpha-2C adrenergic receptor		 537								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097708&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8032110	103994885		CHEMBL3588903				ZINC36286557	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363332	Oc1cc2CCNCC(c3ccccc3)c2cc1O	InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2	JUDKOGFHZYMDMF-UHFFFAOYSA-N	50004923	(+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514	Alpha-2C adrenergic receptor		 83								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004923	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004923&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1242	103918470		CHEMBL505308CHEMBL286080CHEMBL542700		935			1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363333	Cc1ccccc1NCc1cnc[nH]1	InChI=1S/C33H42FN7O5S/c1-3-4-5-6-7-8-14-38(2)29(43)21-41-19-26(31(45)37-33(41)47-23-24-9-11-27(34)12-10-24)16-25-17-36-32(46)40(18-25)22-30(44)39-15-13-35-28(42)20-39/h9-12,17-19H,3-8,13-16,20-23H2,1-2H3,(H,35,42)	QONNLIDVEAFUFJ-UHFFFAOYSA-N	50097711	CHEMBL3588902	Alpha-2C adrenergic receptor		 72								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097711	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097711&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			13178306	103994888		CHEMBL3588902				ZINC37858511	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363334	NCCc1ccccc1-c1cccc(c1)C#N	InChI=1S/C37H50FN7O5S/c1-3-4-5-6-7-8-9-10-11-12-18-42(2)33(47)25-45-23-30(35(49)41-37(45)51-27-28-13-15-31(38)16-14-28)20-29-21-40-36(50)44(22-29)26-34(48)43-19-17-39-32(46)24-43/h13-16,21-23H,3-12,17-20,24-27H2,1-2H3,(H,39,46)	DCTTXTBJFQPRGR-UHFFFAOYSA-N	50097712	CHEMBL3590203	Alpha-2C adrenergic receptor		 12								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097712&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1393724	103994889		CHEMBL3590203				ZINC37858505	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363336	C(C1=NCCN1)c1cccc2ccccc12	InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16)	CNIIGCLFLJGOGP-UHFFFAOYSA-N	50001922	2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; hydrochloride::Albalon::CHEMBL1706::NAPHAZOLINE HYDROCHLORIDE::Nafazair::Naphazoline::Naphazoline Nitrate::Naphcon forte::Opcon::Vasocon::cid_11079	Alpha-2C adrenergic receptor		 2.3								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001922	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001922&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4436	103916289		CHEMBL1706	DB06711		C07898	ZINC00119717	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363337	CN1CCN(CC1)c1ccc(N)cc1	InChI=1S/C11H17N3/c1-13-6-8-14(9-7-13)11-4-2-10(12)3-5-11/h2-5H,6-9,12H2,1H3	MOZNZNKHRXRLLF-UHFFFAOYSA-N	50106345	4-(4-Methyl-piperazin-1-yl)-phenylamine::CHEMBL341473::cid_737253	Alpha-2C adrenergic receptor					<501187					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106345&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			737253	104001900		CHEMBL341473				ZINC00166196	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363338	CC(C)NCc1nccn1Cc1ccccc1C	InChI=1S/C35H48FN5O5S/c1-4-6-7-8-9-10-11-12-13-14-19-39(3)31(42)24-41-23-29(20-28-21-37-34(45)40(22-28)25-32(43)46-5-2)33(44)38-35(41)47-26-27-15-17-30(36)18-16-27/h15-18,21-23H,4-14,19-20,24-26H2,1-3H3	RBRHUWXJXFCGBJ-UHFFFAOYSA-N	50097713	CHEMBL3588911	Alpha-2C adrenergic receptor					 147911					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097713	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097713&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			42669828	103994890		CHEMBL3588911				ZINC37858506	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363339	O=C(CCC1CCCC1)N1CCSC11CCNCC1	InChI=1S/C28H36FN5O3S/c1-4-5-6-7-8-9-14-32(2)25(35)19-34-18-23(15-22-16-30-27(37)33(3)17-22)26(36)31-28(34)38-20-21-10-12-24(29)13-11-21/h10-13,16-18H,4-9,14-15,19-20H2,1-3H3	FRJVLXDYVHUOJC-UHFFFAOYSA-N	50097714	CHEMBL3588910	Alpha-2C adrenergic receptor					<501187					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097714	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097714&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4306793	103994891		CHEMBL3588910				ZINC36286547	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363340	NCC(=O)Nc1ccccc1Oc1ccccc1	InChI=1S/C31H41FN6O5S/c1-3-4-5-6-7-8-14-36(2)28(41)21-38-19-25(29(42)35-31(38)44-22-23-9-11-26(32)12-10-23)16-24-17-34-30(43)37(18-24)20-27(40)33-13-15-39/h9-12,17-19,39H,3-8,13-16,20-22H2,1-2H3,(H,33,40)	WOPCVZFOKRGUKB-UHFFFAOYSA-N	50097715	CHEMBL3588909	Alpha-2C adrenergic receptor					 630957					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097715	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097715&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			770500	103994892		CHEMBL3588909				ZINC36286553	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363341	OC(Cn1ccnc1)c1ccc(Cl)cc1Cl	InChI=1S/C11H10Cl2N2O/c12-8-1-2-9(10(13)5-8)11(16)6-15-4-3-14-7-15/h1-5,7,11,16H,6H2	UKVLTPAGJIYSGN-UHFFFAOYSA-N	50051838	CHEMBL1327	Alpha-2C adrenergic receptor					 338844					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051838&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			32238	313069472		CHEMBL1327					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363342	COc1ccccc1OCC1CNCCO1	InChI=1S/C32H43FN6O4S/c1-4-6-7-8-9-10-16-37(3)29(41)22-39-20-26(30(42)36-32(39)44-23-24-11-13-27(33)14-12-24)17-25-18-35-31(43)38(19-25)21-28(40)34-15-5-2/h11-14,18-20H,4-10,15-17,21-23H2,1-3H3,(H,34,40)	VBNRISKWWMYEMT-UHFFFAOYSA-N	50097716	CHEMBL3588908	Alpha-2C adrenergic receptor					<501187					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097716	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097716&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11333552	103994893		CHEMBL3588908				ZINC36286555	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363352	NCCCN(C(=O)c1ccccc1)c1ccccc1	InChI=1S/C32H44FN5O3S/c1-4-5-6-7-8-9-10-11-12-13-18-36(2)29(39)23-38-22-27(19-26-20-34-31(41)37(3)21-26)30(40)35-32(38)42-24-25-14-16-28(33)17-15-25/h14-17,20-22H,4-13,18-19,23-24H2,1-3H3	RXKGKIOBZCSYKJ-UHFFFAOYSA-N	50097717	CHEMBL3588907	Alpha-2C adrenergic receptor					<501187					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097717	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097717&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4657799	103994894		CHEMBL3588907				ZINC36286534	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363473	C(NCc1cccnc1)c1c[nH]c(n1)-c1ccccc1	InChI=1S/C34H40FN5O3S/c1-3-4-5-6-7-11-18-39(2)31(41)23-40-22-29(32(42)38-34(40)44-25-27-14-16-30(35)17-15-27)19-28-20-36-33(37-21-28)43-24-26-12-9-8-10-13-26/h8-10,12-17,20-22H,3-7,11,18-19,23-25H2,1-2H3	RFPZWTOAEAWLHV-UHFFFAOYSA-N	50097719	CHEMBL3588905	Alpha-2C adrenergic receptor					 478630					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097719	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097719&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46743607	103994896		CHEMBL3588905				ZINC36286541	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363474	Brc1cccc(Cn2ccnc2)c1	InChI=1S/C10H9BrN2/c11-10-3-1-2-9(6-10)7-13-5-4-12-8-13/h1-6,8H,7H2	BGYZLOIBJCHCTI-UHFFFAOYSA-N	50307216	1-(3-Bromobenzyl)-1H-imidazole::CHEMBL598391	Alpha-2C adrenergic receptor					<501187					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50307216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50307216&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10220337	104161577		CHEMBL598391				ZINC12370275	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363488	C(Nc1ccccc1-c1cccnc1)c1ccncc1	InChI=1S/C31H42FN5O3S/c1-3-4-5-6-7-8-9-10-11-12-17-36(2)28(38)22-37-21-26(18-25-19-33-30(40)34-20-25)29(39)35-31(37)41-23-24-13-15-27(32)16-14-24/h13-16,19-21H,3-12,17-18,22-23H2,1-2H3,(H,33,34,40)	LPFVTHQVZUGCCO-UHFFFAOYSA-N	50097707	CHEMBL3588904	Alpha-2C adrenergic receptor					 3467					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097707&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122180567	103994884		CHEMBL3588904				ZINC36286560	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363495	NCCSc1nc2ccccc2o1	InChI=1S/C9H10N2OS/c10-5-6-13-9-11-7-3-1-2-4-8(7)12-9/h1-4H,5-6,10H2	LIZDKHZOMRDDRY-UHFFFAOYSA-N	50421231	CHEMBL2087646	Alpha-2C adrenergic receptor					 3162					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421231	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421231&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			434526	163370255		CHEMBL2087646				ZINC06584354	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363500	Cc1ccccc1NCc1ccncc1	InChI=1S/C27H34FN5O3S/c1-3-4-5-6-7-8-13-32(2)24(34)18-33-17-22(14-21-15-29-26(36)30-16-21)25(35)31-27(33)37-19-20-9-11-23(28)12-10-20/h9-12,15-17H,3-8,13-14,18-19H2,1-2H3,(H,29,30,36)	QCDCEUHORMYOQN-UHFFFAOYSA-N	50097708	CHEMBL3588903	Alpha-2C adrenergic receptor					<501187					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097708&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8032110	103994885		CHEMBL3588903				ZINC36286557	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363505	Oc1cc2CCNCC(c3ccccc3)c2cc1O	InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2	JUDKOGFHZYMDMF-UHFFFAOYSA-N	50004923	(+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514	Alpha-2C adrenergic receptor					 1380					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004923	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004923&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1242	103918470		CHEMBL505308CHEMBL286080CHEMBL542700		935			1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363520	Cc1ccccc1NCc1cnc[nH]1	InChI=1S/C33H42FN7O5S/c1-3-4-5-6-7-8-14-38(2)29(43)21-41-19-26(31(45)37-33(41)47-23-24-9-11-27(34)12-10-24)16-25-17-36-32(46)40(18-25)22-30(44)39-15-13-35-28(42)20-39/h9-12,17-19H,3-8,13-16,20-23H2,1-2H3,(H,35,42)	QONNLIDVEAFUFJ-UHFFFAOYSA-N	50097711	CHEMBL3588902	Alpha-2C adrenergic receptor					 174					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097711	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097711&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			13178306	103994888		CHEMBL3588902				ZINC37858511	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363523	NCCc1ccccc1-c1cccc(c1)C#N	InChI=1S/C37H50FN7O5S/c1-3-4-5-6-7-8-9-10-11-12-18-42(2)33(47)25-45-23-30(35(49)41-37(45)51-27-28-13-15-31(38)16-14-28)20-29-21-40-36(50)44(22-29)26-34(48)43-19-17-39-32(46)24-43/h13-16,21-23H,3-12,17-20,24-27H2,1-2H3,(H,39,46)	DCTTXTBJFQPRGR-UHFFFAOYSA-N	50097712	CHEMBL3590203	Alpha-2C adrenergic receptor					<501187					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097712&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1393724	103994889		CHEMBL3590203				ZINC37858505	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363535	C(C1=NCCN1)c1cccc2ccccc12	InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16)	CNIIGCLFLJGOGP-UHFFFAOYSA-N	50001922	2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; hydrochloride::Albalon::CHEMBL1706::NAPHAZOLINE HYDROCHLORIDE::Nafazair::Naphazoline::Naphazoline Nitrate::Naphcon forte::Opcon::Vasocon::cid_11079	Alpha-2C adrenergic receptor					 55					ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001922	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001922&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4436	103916289		CHEMBL1706	DB06711		C07898	ZINC00119717	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363543	COc1ccc(cc1)C1NCCCn2cccc12	InChI=1S/C30H39FN6O4S/c1-4-5-6-7-8-9-14-35(3)27(39)20-37-18-24(15-23-16-33-29(41)36(17-23)19-26(38)32-2)28(40)34-30(37)42-21-22-10-12-25(31)13-11-22/h10-13,16-18H,4-9,14-15,19-21H2,1-3H3,(H,32,38)	REGPEFKGXBCZMO-UHFFFAOYSA-N	50097720	CHEMBL3588912	Alpha-2C adrenergic receptor		 13804								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097720	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097720&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			42656257	103994897		CHEMBL3588912				ZINC14127971	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363549	CN1CCN(CC1)c1ccccc1N	InChI=1S/C29H38FN5O3S/c1-4-6-7-8-9-10-15-33(3)26(36)20-35-19-24(16-23-17-31-28(38)34(5-2)18-23)27(37)32-29(35)39-21-22-11-13-25(30)14-12-22/h11-14,17-19H,4-10,15-16,20-21H2,1-3H3	SPJIPWQWZQJJNL-UHFFFAOYSA-N	50097721	CHEMBL1879790	Alpha-2C adrenergic receptor		 240								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097721	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097721&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	QSS	6VA5	286547	103994898		CHEMBL1879790				ZINC36286563	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363551	CN1CCN(CC1)c1cccc(N)c1	InChI=1S/C29H36FN5O5S/c1-3-4-5-6-7-8-13-33(2)25(36)18-35-17-23(14-22-15-31-28(40)34(16-22)19-26(37)38)27(39)32-29(35)41-20-21-9-11-24(30)12-10-21/h9-12,15-17H,3-8,13-14,18-20H2,1-2H3,(H,37,38)	FRDCMLAYXLLSQS-UHFFFAOYSA-N	50097722	CHEMBL129399	Alpha-2C adrenergic receptor		 562								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097722&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11564613	103994899		CHEMBL129399				ZINC14127970	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363558	CN1CCN(CC1)c1ccc(N)cc1	InChI=1S/C11H17N3/c1-13-6-8-14(9-7-13)11-4-2-10(12)3-5-11/h2-5H,6-9,12H2,1H3	MOZNZNKHRXRLLF-UHFFFAOYSA-N	50106345	4-(4-Methyl-piperazin-1-yl)-phenylamine::CHEMBL341473::cid_737253	Alpha-2C adrenergic receptor		 1514								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106345&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			737253	104001900		CHEMBL341473				ZINC00166196	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363562	CC(C)NCc1nccn1Cc1ccccc1C	InChI=1S/C35H48FN5O5S/c1-4-6-7-8-9-10-11-12-13-14-19-39(3)31(42)24-41-23-29(20-28-21-37-34(45)40(22-28)25-32(43)46-5-2)33(44)38-35(41)47-26-27-15-17-30(36)18-16-27/h15-18,21-23H,4-14,19-20,24-26H2,1-3H3	RBRHUWXJXFCGBJ-UHFFFAOYSA-N	50097713	CHEMBL3588911	Alpha-2C adrenergic receptor		 22387								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097713	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097713&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			42669828	103994890		CHEMBL3588911				ZINC37858506	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363569	O=C(CCC1CCCC1)N1CCSC11CCNCC1	InChI=1S/C28H36FN5O3S/c1-4-5-6-7-8-9-14-32(2)25(35)19-34-18-23(15-22-16-30-27(37)33(3)17-22)26(36)31-28(34)38-20-21-10-12-24(29)13-11-21/h10-13,16-18H,4-9,14-15,19-20H2,1-3H3	FRJVLXDYVHUOJC-UHFFFAOYSA-N	50097714	CHEMBL3588910	Alpha-2C adrenergic receptor		 15488								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097714	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097714&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4306793	103994891		CHEMBL3588910				ZINC36286547	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363578	NCC(=O)Nc1ccccc1Oc1ccccc1	InChI=1S/C31H41FN6O5S/c1-3-4-5-6-7-8-14-36(2)28(41)21-38-19-25(29(42)35-31(38)44-22-23-9-11-26(32)12-10-23)16-24-17-34-30(43)37(18-24)20-27(40)33-13-15-39/h9-12,17-19,39H,3-8,13-16,20-22H2,1-2H3,(H,33,40)	WOPCVZFOKRGUKB-UHFFFAOYSA-N	50097715	CHEMBL3588909	Alpha-2C adrenergic receptor		 15488								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097715	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097715&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			770500	103994892		CHEMBL3588909				ZINC36286553	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363592	OC(Cn1ccnc1)c1ccc(Cl)cc1Cl	InChI=1S/C11H10Cl2N2O/c12-8-1-2-9(10(13)5-8)11(16)6-15-4-3-14-7-15/h1-5,7,11,16H,6H2	UKVLTPAGJIYSGN-UHFFFAOYSA-N	50051838	CHEMBL1327	Alpha-2C adrenergic receptor		 15136								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051838&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			32238	313069472		CHEMBL1327					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363593	COc1ccccc1OCC1CNCCO1	InChI=1S/C32H43FN6O4S/c1-4-6-7-8-9-10-16-37(3)29(41)22-39-20-26(30(42)36-32(39)44-23-24-11-13-27(33)14-12-24)17-25-18-35-31(43)38(19-25)21-28(40)34-15-5-2/h11-14,18-20H,4-10,15-17,21-23H2,1-3H3,(H,34,40)	VBNRISKWWMYEMT-UHFFFAOYSA-N	50097716	CHEMBL3588908	Alpha-2C adrenergic receptor		 10471								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097716	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097716&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11333552	103994893		CHEMBL3588908				ZINC36286555	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363599	NCCCN(C(=O)c1ccccc1)c1ccccc1	InChI=1S/C32H44FN5O3S/c1-4-5-6-7-8-9-10-11-12-13-18-36(2)29(39)23-38-22-27(19-26-20-34-31(41)37(3)21-26)30(40)35-32(38)42-24-25-14-16-28(33)17-15-25/h14-17,20-22H,4-13,18-19,23-24H2,1-3H3	RXKGKIOBZCSYKJ-UHFFFAOYSA-N	50097717	CHEMBL3588907	Alpha-2C adrenergic receptor		 8318								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097717	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097717&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4657799	103994894		CHEMBL3588907				ZINC36286534	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363601	CCNCC(=O)N1CCn2cccc2C1c1cccc(Cl)c1	InChI=1S/C34H47FN6O4S/c1-4-5-6-7-8-9-10-11-12-13-18-39(3)31(43)24-41-22-28(19-27-20-37-33(45)40(21-27)23-30(42)36-2)32(44)38-34(41)46-25-26-14-16-29(35)17-15-26/h14-17,20-22H,4-13,18-19,23-25H2,1-3H3,(H,36,42)	FNLKETQXRMMFDO-UHFFFAOYSA-N	50097718	CHEMBL3588906	Alpha-2C adrenergic receptor		 7244								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097718&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46743614	103994895		CHEMBL3588906				ZINC37858510	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50363658	C(NCc1cccnc1)c1c[nH]c(n1)-c1ccccc1	InChI=1S/C34H40FN5O3S/c1-3-4-5-6-7-11-18-39(2)31(41)23-40-22-29(32(42)38-34(40)44-25-27-14-16-30(35)17-15-27)19-28-20-36-33(37-21-28)43-24-26-12-9-8-10-13-26/h8-10,12-17,20-22H,3-7,11,18-19,23-25H2,1-2H3	RFPZWTOAEAWLHV-UHFFFAOYSA-N	50097719	CHEMBL3588905	Alpha-2C adrenergic receptor		 5248								ChEMBL	10.1016/j.bmc.2015.01.013	10.7270/Q2GM892T	25648685			Szollosi, E; Bobok, A; Kiss, L; Vass, M; Kurkó, D; Kolok, S; Visegrády, A; Keseru, GM	Gedeon Richter Plc., Gy&#65533;mroi&#65533;t 19-21, Budapest H-1103, Hungary.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097719	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097719&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46743607	103994896		CHEMBL3588905				ZINC36286541	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50394081	C[C@@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	NMSAVNXFCXMJJY-GFCCVEGCSA-N	50218115	(R)-2-[1-(3'-nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL242693	Alpha-2C adrenergic receptor					 10					ChEMBL	10.1021/jm061487a	10.7270/Q2W095NP	17630725			Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M	Universit&#224; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218115&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757089	104091931		CHEMBL242693				ZINC13585593	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50382422	CC[C@@H]1O[C@@](\C=C\C2CC2)(c2c(F)c(F)ccc2NC1=O)C(F)(F)F	InChI=1S/C17H16F5NO2/c1-2-12-15(24)23-11-6-5-10(18)14(19)13(11)16(25-12,17(20,21)22)8-7-9-3-4-9/h5-9,12H,2-4H2,1H3,(H,23,24)/b8-7+/t12-,16-/m0/s1	MSJCAWWJIHDUAU-OSTNNTLRSA-N	50269979	CHEMBL515170::r-5-(2-E-cyclopropylvinyl)-t-3-ethyl-6,7-difluoro-5-(trifluoromethyl)benzo[e][1,4]-oxazepin-2(1H,3H,5H)-one	Alpha-2C adrenergic receptor			 10400							ChEMBL	10.1073/pnas.0605125104	10.7270/Q28P608V	17428923			Carter, PH; Liu, RQ; Foster, WR; Tamasi, JA; Tebben, AJ; Favata, M; Staal, A; Cvijic, ME; French, MH; Dell, V; Apanovitch, D; Lei, M; Zhao, Q; Cunningham, M; Decicco, CP; Trzaskos, JM; Feyen, JH	Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50269979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50269979&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16220269	104115377		CHEMBL515170				ZINC40404539	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50390267	FCc1nc(cs1)C#Cc1cc(F)cc(c1)C#N	InChI=1S/C13H6F2N2S/c14-6-13-17-12(8-18-13)2-1-9-3-10(7-16)5-11(15)4-9/h3-5,8H,6H2	WTLBLIGPXACYET-UHFFFAOYSA-N	50215552	3-fluoro-5-(2-(2-(fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile::CHEMBL229429	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1021/jm0701268	10.7270/Q2FB52NB	17571866			Simeon, FG; Brown, AK; Zoghbi, SS; Patterson, VM; Innis, RB; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215552&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16737207	104090124		CHEMBL229429		6434		ZINC28701631	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50386433	Cc1n[nH]c2cc(OCCNC[C@H](O)c3cccc(NS(C)(=O)=O)c3)ccc12	InChI=1S/C19H24N4O4S/c1-13-17-7-6-16(11-18(17)22-21-13)27-9-8-20-12-19(24)14-4-3-5-15(10-14)23-28(2,25)26/h3-7,10-11,19-20,23-24H,8-9,12H2,1-2H3,(H,21,22)/t19-/m0/s1	ITIDAHAJICCYKL-IBGZPJMESA-N	50108094	CHEMBL3601200	Alpha-2C adrenergic receptor					>10000					ChEMBL	10.1021/acs.jmedchem.5b00638	10.7270/Q2NG4SDR	26125514			Wada, Y; Shirahashi, H; Iwanami, T; Ogawa, M; Nakano, S; Morimoto, A; Kasahara, K; Tanaka, E; Takada, Y; Ohashi, S; Mori, M; Shuto, S	Asahi Kasei Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108094&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10135864	104003316		CHEMBL3601200				ZINC13471866	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50401692	COc1cc2C(CN(C)C3Cc4cc5OCOc5cc4-c(c1OC)c23)c1ccccc1	InChI=1S/C26H25NO4/c1-27-13-19(15-7-5-4-6-8-15)18-12-23(28-2)26(29-3)25-17-11-22-21(30-14-31-22)10-16(17)9-20(27)24(18)25/h4-8,10-12,19-20H,9,13-14H2,1-3H3	XYYAWEJOUNEPTR-UHFFFAOYSA-N	50114872	CHEMBL3608450	Alpha-2C adrenergic receptor		 433								ChEMBL	10.1016/j.bmcl.2015.07.012	10.7270/Q2MW2JXN	26227772			Kapadia, N; Harding, WW	City University of New York	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114872	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114872&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122186880	319493993		CHEMBL3608450					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50431379	CNC(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1	InChI=1S/C28H31ClN2O2/c1-30-26(32)28(23-8-4-2-5-9-23,24-10-6-3-7-11-24)18-21-31-19-16-27(33,17-20-31)22-12-14-25(29)15-13-22/h2-15,33H,16-21H2,1H3,(H,30,32)	ZMOPTLXEYOVARP-UHFFFAOYSA-N	50253754	4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-methyl-2,2-diphenylbutanamide::CHEMBL1627	Alpha-2C adrenergic receptor		 2.4								ChEMBL	10.1021/jm800510m	10.7270/Q2BV7GFM	18783208			Lazarova, N; Zoghbi, SS; Hong, J; Seneca, N; Tuan, E; Gladding, RL; Liow, JS; Taku, A; Innis, RB; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253754&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9805944	104106206	64043	CHEMBL1627				ZINC21981239	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432729	O=C(NCCN1CCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1	InChI=1S/C27H30N4O4/c32-26(23-9-6-12-29-27(23)35-21-7-2-1-3-8-21)28-13-14-30-15-17-31(18-16-30)19-22-20-33-24-10-4-5-11-25(24)34-22/h1-12,22H,13-20H2,(H,28,32)	SJTUPIJPFNBFHK-UHFFFAOYSA-N	50263620	CHEMBL478026::N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)piperazin-1-yl)ethyl)-2-phenoxynicotinamide	Alpha-2C adrenergic receptor		 3								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263620&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579186	104111893		CHEMBL478026				ZINC40406768	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432730	O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1cccc(c1)C#N	InChI=1S/C29H31N5O4/c30-19-22-6-3-7-23(18-22)38-29-25(8-4-11-32-29)28(35)31-12-15-33-13-5-14-34(17-16-33)20-24-21-36-26-9-1-2-10-27(26)37-24/h1-4,6-11,18,24H,5,12-17,20-21H2,(H,31,35)	YGAFMXXNJBOVBA-UHFFFAOYSA-N	50263621	2-(3-cyanophenoxy)-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL515331	Alpha-2C adrenergic receptor		 0.800000								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263621&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579187	104111894		CHEMBL515331				ZINC40918054	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432734	O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1	InChI=1S/C22H28N4O3/c27-22(18-5-3-8-23-15-18)24-9-12-25-10-4-11-26(14-13-25)16-19-17-28-20-6-1-2-7-21(20)29-19/h1-3,5-8,15,19H,4,9-14,16-17H2,(H,24,27)	POCXNIFHHUXWMU-UHFFFAOYSA-N	50263674	CHEMBL476774::N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide	Alpha-2C adrenergic receptor		 16								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263674&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579231	104111927		CHEMBL476774				ZINC40916962	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432735	C(CN1CCCN(CC2COc3ccccc3O2)CC1)OCc1cccnc1Oc1ccccc1	InChI=1S/C28H33N3O4/c1-2-9-24(10-3-1)35-28-23(8-6-13-29-28)21-32-19-18-30-14-7-15-31(17-16-30)20-25-22-33-26-11-4-5-12-27(26)34-25/h1-6,8-13,25H,7,14-22H2	AFRRMVBYOMNLHN-UHFFFAOYSA-N	50263724	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-(2-((2-phenoxypyridin-3-yl)methoxy)ethyl)-1,4-diazepane::CHEMBL491419	Alpha-2C adrenergic receptor		 2.5								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263724&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579271	104111963		CHEMBL491419				ZINC45498778	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432736	C(C1COc2ccccc2O1)N1CCCN(Cc2nc(no2)-c2cccnc2Oc2ccccc2)CC1	InChI=1S/C28H29N5O4/c1-2-8-21(9-3-1)36-28-23(10-6-13-29-28)27-30-26(37-31-27)19-33-15-7-14-32(16-17-33)18-22-20-34-24-11-4-5-12-25(24)35-22/h1-6,8-13,22H,7,14-20H2	YWALOGYVALOLTL-UHFFFAOYSA-N	50263725	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-((3-(2-phenoxypyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)-1,4-diazepane::CHEMBL491420	Alpha-2C adrenergic receptor		 1.9								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263725&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579272	104111964		CHEMBL491420				ZINC40424119	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432738	C(C1COc2ccccc2C1)N1CCN(Cc2ccccc2)CC1	InChI=1S/C21H26N2O/c1-2-6-18(7-3-1)15-22-10-12-23(13-11-22)16-19-14-20-8-4-5-9-21(20)24-17-19/h1-9,19H,10-17H2	QDCUYFUPXSPBMW-UHFFFAOYSA-N	50159021	1-Benzyl-4-chroman-3-ylmethyl-piperazine::1-benzyl-4-((3,4-dihydro-2H-chromen-3-yl)methyl)piperazine::CHEMBL362699	Alpha-2C adrenergic receptor		>500								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159021&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11338418	104045621		CHEMBL362699				ZINC22933155	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432739	O=C(NCCN1CCCN(C[C@H]2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1	InChI=1S/C28H32N4O4/c33-27(24-10-6-13-30-28(24)36-22-8-2-1-3-9-22)29-14-17-31-15-7-16-32(19-18-31)20-23-21-34-25-11-4-5-12-26(25)35-23/h1-6,8-13,23H,7,14-21H2,(H,29,33)/t23-/m0/s1	RNPCOHCWKNMBRI-QHCPKHFHSA-N	50263774	(S)-N-{2-[4-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1,4]diazepan-1-yl]-ethyl}-2-phenoxy-nicotinamide::CHEMBL524153	Alpha-2C adrenergic receptor		 0.900000								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263774&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25110718	104111991		CHEMBL524153				ZINC40951657	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432766	COc1ccccc1N1CCN(CC2COc3ccccc3O2)CC1	InChI=1S/C20H24N2O3/c1-23-18-7-3-2-6-17(18)22-12-10-21(11-13-22)14-16-15-24-19-8-4-5-9-20(19)25-16/h2-9,16H,10-15H2,1H3	IQDINXFLUAYBCC-UHFFFAOYSA-N	50263618	1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-4-(2-methoxyphenyl)piperazine::CHEMBL518592	Alpha-2C adrenergic receptor		 23								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263618&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579184	104111891		CHEMBL518592				ZINC20775759	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432767	O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1	InChI=1S/C28H32N4O4/c33-27(24-10-6-13-30-28(24)36-22-8-2-1-3-9-22)29-14-17-31-15-7-16-32(19-18-31)20-23-21-34-25-11-4-5-12-26(25)35-23/h1-6,8-13,23H,7,14-21H2,(H,29,33)	RNPCOHCWKNMBRI-UHFFFAOYSA-N	50263619	CHEMBL477816::N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)-2-phenoxynicotinamide	Alpha-2C adrenergic receptor		 25								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263619&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579185	104111892		CHEMBL477816				ZINC40421976	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432769	CC(C)(C)Nc1ncccc1C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H37N5O3/c1-26(2,3)29-24-21(8-6-11-27-24)25(32)28-12-15-30-13-7-14-31(17-16-30)18-20-19-33-22-9-4-5-10-23(22)34-20/h4-6,8-11,20H,7,12-19H2,1-3H3,(H,27,29)(H,28,32)	IPSCUIDJZTXJJO-UHFFFAOYSA-N	50263671	2-(tert-butylamino)-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL477608	Alpha-2C adrenergic receptor		 31								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263671&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579228	104111924		CHEMBL477608				ZINC40916745	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432770	CCCCOc1ncccc1C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H36N4O4/c1-2-3-18-32-26-22(8-6-11-28-26)25(31)27-12-15-29-13-7-14-30(17-16-29)19-21-20-33-23-9-4-5-10-24(23)34-21/h4-6,8-11,21H,2-3,7,12-20H2,1H3,(H,27,31)	OYOGQACTFBHTOD-UHFFFAOYSA-N	50263672	2-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)nicotinamide::CHEMBL514837	Alpha-2C adrenergic receptor		 4.8								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263672&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579229	104111925		CHEMBL514837				ZINC40408846	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432771	CCCCOc1cccc(n1)C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1	InChI=1S/C26H36N4O4/c1-2-3-18-32-25-11-6-8-22(28-25)26(31)27-12-15-29-13-7-14-30(17-16-29)19-21-20-33-23-9-4-5-10-24(23)34-21/h4-6,8-11,21H,2-3,7,12-20H2,1H3,(H,27,31)	RVIXAJHMKWFIKC-UHFFFAOYSA-N	50263673	6-butoxy-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)picolinamide::CHEMBL476569	Alpha-2C adrenergic receptor		 3.8								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263673&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579230	104111926		CHEMBL476569				ZINC40917448	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432774	C(C1CCc2ccccc2O1)N1CCN(Cc2ccccc2)CC1	InChI=1S/C21H26N2O/c1-2-6-18(7-3-1)16-22-12-14-23(15-13-22)17-20-11-10-19-8-4-5-9-21(19)24-20/h1-9,20H,10-17H2	AJZBPCAHQHCXMX-UHFFFAOYSA-N	50159018	1-Benzyl-4-chroman-2-ylmethyl-piperazine::1-benzyl-4-((3,4-dihydro-2H-chromen-2-yl)methyl)piperazine::CHEMBL179648	Alpha-2C adrenergic receptor		 21								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159018&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10758200	104045618		CHEMBL179648				ZINC22445891	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50432796	O=C(NCCN1CCCN(C[C@@H]2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1	InChI=1S/C28H32N4O4/c33-27(24-10-6-13-30-28(24)36-22-8-2-1-3-9-22)29-14-17-31-15-7-16-32(19-18-31)20-23-21-34-25-11-4-5-12-26(25)35-23/h1-6,8-13,23H,7,14-21H2,(H,29,33)/t23-/m1/s1	RNPCOHCWKNMBRI-HSZRJFAPSA-N	50263775	(R)-N-(2-(4-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1,4-diazepan-1-yl)ethyl)-2-phenoxynicotinamide::CHEMBL488974	Alpha-2C adrenergic receptor		 9.2								ChEMBL	10.1016/j.bmcl.2008.08.055	10.7270/Q2N58M5Z	18799310			Patel, SD; Habeski, WM; Min, H; Zhang, J; Roof, R; Snyder, B; Bora, G; Campbell, B; Li, C; Hidayetoglu, D; Johnson, DS; Chaudhry, A; Charlton, ME; Kablaoui, NM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263775	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263775&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44579303	104111992		CHEMBL488974					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456642	COc1c(OCCF)cccc1C(O)C1CCN(CCc2ccc(F)cc2)CC1	InChI=1S/C23H29F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18,22,27H,9-16H2,1H3	QCFZUTYIUYQTPW-UHFFFAOYSA-N	50232152	(1-(4-fluorophenethyl)piperidin-4-yl)(3-(2-fluoroethoxy)-2-methoxyphenyl)methanol::(3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::CHEMBL402143	Alpha-2C adrenergic receptor		 148								ChEMBL	10.1016/j.bmc.2009.03.021	10.7270/Q21V5DW2	19329329			Herth, MM; Kramer, V; Piel, M; Palner, M; Riss, PJ; Knudsen, GM; Rosch, F	Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50232152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50232152&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44455426	104055426		CHEMBL402143				ZINC29128987	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456643	COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1	InChI=1S/C23H27F2NO3/c1-28-23-20(3-2-4-21(23)29-16-12-24)22(27)18-10-14-26(15-11-18)13-9-17-5-7-19(25)8-6-17/h2-8,18H,9-16H2,1H3	HVJOIRMQZXEGPW-UHFFFAOYSA-N	50267508	4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fluorophenylethyl)-piperidine::CHEMBL516088	Alpha-2C adrenergic receptor		 333								ChEMBL	10.1016/j.bmc.2009.03.021	10.7270/Q21V5DW2	19329329			Herth, MM; Kramer, V; Piel, M; Palner, M; Riss, PJ; Knudsen, GM; Rosch, F	Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50267508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50267508&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44582676	104114318		CHEMBL516088				ZINC40918122	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456644	COc1c(OCCF)cccc1C(O)C1CCN(CCc2ccc(C)cc2)CC1	InChI=1S/C24H32FNO3/c1-18-6-8-19(9-7-18)10-14-26-15-11-20(12-16-26)23(27)21-4-3-5-22(24(21)28-2)29-17-13-25/h3-9,20,23,27H,10-17H2,1-2H3	MJKRYUCQHJLOIV-UHFFFAOYSA-N	50267510	(3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluylphenylethyl)-piperidine-4-yl)-methanol::CHEMBL476839	Alpha-2C adrenergic receptor		 143								ChEMBL	10.1016/j.bmc.2009.03.021	10.7270/Q21V5DW2	19329329			Herth, MM; Kramer, V; Piel, M; Palner, M; Riss, PJ; Knudsen, GM; Rosch, F	Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50267510	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50267510&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44582678	104114320		CHEMBL476839				ZINC40402851	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456645	COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc(C)cc2)CC1	InChI=1S/C24H30FNO3/c1-18-6-8-19(9-7-18)10-14-26-15-11-20(12-16-26)23(27)21-4-3-5-22(24(21)28-2)29-17-13-25/h3-9,20H,10-17H2,1-2H3	PPXOTGGYVKBLCQ-UHFFFAOYSA-N	50267554	4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-toluylethyl)-piperidine::CHEMBL490632	Alpha-2C adrenergic receptor		 154								ChEMBL	10.1016/j.bmc.2009.03.021	10.7270/Q21V5DW2	19329329			Herth, MM; Kramer, V; Piel, M; Palner, M; Riss, PJ; Knudsen, GM; Rosch, F	Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50267554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50267554&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44582705	104114364		CHEMBL490632				ZINC40950365	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456782	COc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C17H22N2O/c1-4-9-19(10-5-2)11-8-14-13-18-17-7-6-15(20-3)12-16(14)17/h4-7,12-13,18H,1-2,8-11H2,3H3	HGRHWEAUHXYNNP-UHFFFAOYSA-N	50435344	CHEMBL2391541	Alpha-2C adrenergic receptor		 1479								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50435344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50435344&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			50878551	175447661		CHEMBL2391541				ZINC40448582	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456783	Fc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19FN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	ALTKABGEMCJWJH-UHFFFAOYSA-N	50140053	CHEMBL3754496	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140053&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127026052	104029803		CHEMBL3754496				ZINC28224295	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456784	Brc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19BrN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	JWPAYBAIIARWMG-UHFFFAOYSA-N	50140055	CHEMBL3754166	Alpha-2C adrenergic receptor		 398								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140055&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036953	104029805		CHEMBL3754166				ZINC28224430	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456785	Cc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C17H22N2/c1-4-9-19(10-5-2)11-8-15-13-18-17-7-6-14(3)12-16(15)17/h4-7,12-13,18H,1-2,8-11H2,3H3	HTDIOUCPOHFDQH-UHFFFAOYSA-N	50140056	CHEMBL3753318	Alpha-2C adrenergic receptor		 1096								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140056	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140056&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036186	104029806		CHEMBL3753318				ZINC36311031	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456415	C=CCN(CCc1c[nH]c2ccccc12)CC=C	InChI=1S/C16H20N2/c1-3-10-18(11-4-2)12-9-14-13-17-16-8-6-5-7-15(14)16/h3-8,13,17H,1-2,9-12H2	LQEATNFJCMVKAC-UHFFFAOYSA-N	50140058	CHEMBL3752576	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140058&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24839550	104029808		CHEMBL3752576				ZINC36311040	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456416	Clc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19ClN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	XRJGWSMTLAFHBN-UHFFFAOYSA-N	50140054	CHEMBL3752900	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140054&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036932	104029804		CHEMBL3752900				ZINC28225245	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456417	Brc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19BrN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	JWPAYBAIIARWMG-UHFFFAOYSA-N	50140055	CHEMBL3754166	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140055&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036953	104029805		CHEMBL3754166				ZINC28224430	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456418	C=CCN(CCc1c[nH]c2ccccc12)CC=C	InChI=1S/C16H20N2/c1-3-10-18(11-4-2)12-9-14-13-17-16-8-6-5-7-15(14)16/h3-8,13,17H,1-2,9-12H2	LQEATNFJCMVKAC-UHFFFAOYSA-N	50140058	CHEMBL3752576	Alpha-2C adrenergic receptor		 891								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140058&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24839550	104029808		CHEMBL3752576				ZINC36311040	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456419	Fc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19FN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	ALTKABGEMCJWJH-UHFFFAOYSA-N	50140053	CHEMBL3754496	Alpha-2C adrenergic receptor		 794								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140053&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127026052	104029803		CHEMBL3754496				ZINC28224295	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456420	Clc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C16H19ClN2/c1-3-8-19(9-4-2)10-7-13-12-18-16-6-5-14(17)11-15(13)16/h3-6,11-12,18H,1-2,7-10H2	XRJGWSMTLAFHBN-UHFFFAOYSA-N	50140054	CHEMBL3752900	Alpha-2C adrenergic receptor		 631								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140054&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036932	104029804		CHEMBL3752900				ZINC28225245	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456426	Cc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C17H22N2/c1-4-9-19(10-5-2)11-8-15-13-18-17-7-6-14(3)12-16(15)17/h4-7,12-13,18H,1-2,8-11H2,3H3	HTDIOUCPOHFDQH-UHFFFAOYSA-N	50140056	CHEMBL3753318	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140056	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140056&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127036186	104029806		CHEMBL3753318				ZINC36311031	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50456427	COc1ccc2[nH]cc(CCN(CC=C)CC=C)c2c1	InChI=1S/C17H22N2O/c1-4-9-19(10-5-2)11-8-14-13-18-17-7-6-15(20-3)12-16(14)17/h4-7,12-13,18H,1-2,8-11H2,3H3	HGRHWEAUHXYNNP-UHFFFAOYSA-N	50435344	CHEMBL2391541	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmcl.2015.12.053	10.7270/Q24F1SKV	26739781			Cozzi, NV; Daley, PF	The Alexander Shulgin Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50435344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50435344&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			50878551	175447661		CHEMBL2391541				ZINC40448582	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50471059	Cl.NCC1CC1c1cc(F)c(F)cc1OCC=C	InChI=1S/C13H15F2NO.ClH/c1-2-3-17-13-6-12(15)11(14)5-10(13)9-4-8(9)7-16;/h2,5-6,8-9H,1,3-4,7,16H2;1H	XGCOQOYOBQPELW-UHFFFAOYSA-N	50148852	CHEMBL3769968	Alpha-2C adrenergic receptor		 275								ChEMBL	10.1021/acs.jmedchem.5b01153	10.7270/Q28C9Z4P	26704965			Cheng, J; Giguere, PM; Schmerberg, CM; Pogorelov, VM; Rodriguiz, RM; Huang, XP; Zhu, H; McCorvy, JD; Wetsel, WC; Roth, BL; Kozikowski, AP	University of Illinois at Chicago	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50148852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50148852&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44346723	104037038		CHEMBL3769968				ZINC27194094	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50471170	Cl.NCC1CC1c1cc(F)c(F)cc1OCC=C	InChI=1S/C13H15F2NO.ClH/c1-2-3-17-13-6-12(15)11(14)5-10(13)9-4-8(9)7-16;/h2,5-6,8-9H,1,3-4,7,16H2;1H	XGCOQOYOBQPELW-UHFFFAOYSA-N	50148852	CHEMBL3769968	Alpha-2C adrenergic receptor		 278								ChEMBL	10.1021/acs.jmedchem.5b01153	10.7270/Q28C9Z4P	26704965			Cheng, J; Giguere, PM; Schmerberg, CM; Pogorelov, VM; Rodriguiz, RM; Huang, XP; Zhu, H; McCorvy, JD; Wetsel, WC; Roth, BL; Kozikowski, AP	University of Illinois at Chicago	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50148852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50148852&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44346723	104037038		CHEMBL3769968				ZINC27194094	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564016	Brc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	XYLJNLCSTIOKRM-UHFFFAOYSA-N	34572	BRIMONIDINE::CHEMBL844::MLS000069370::SMR000058355::UK 14,304::cid_2435	Alpha-2C adrenergic receptor					 9.5					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34572&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J59	7EJ8	2435	252617225	3175	CHEMBL844	DB00484	520	C07886	ZINC21303210	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564018	Brc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	XYLJNLCSTIOKRM-UHFFFAOYSA-N	34572	BRIMONIDINE::CHEMBL844::MLS000069370::SMR000058355::UK 14,304::cid_2435	Alpha-2C adrenergic receptor		 83								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34572&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J59	7EJ8	2435	252617225	3175	CHEMBL844	DB00484	520	C07886	ZINC21303210	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564021	CC1CN=C(Nc2ccc3nccnc3c2Br)N1	InChI=1S/C12H12BrN5/c1-7-6-16-12(17-7)18-8-2-3-9-11(10(8)13)15-5-4-14-9/h2-5,7H,6H2,1H3,(H2,16,17,18)	XBTUHMKOYJCXOJ-UHFFFAOYSA-N	50213345	CHEMBL72995	Alpha-2C adrenergic receptor		 646								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213345&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44312036	376070925		CHEMBL72995					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564027	CC1CN=C(Nc2ccc3nccnc3c2Br)N1	InChI=1S/C12H12BrN5/c1-7-6-16-12(17-7)18-8-2-3-9-11(10(8)13)15-5-4-14-9/h2-5,7H,6H2,1H3,(H2,16,17,18)	XBTUHMKOYJCXOJ-UHFFFAOYSA-N	50213345	CHEMBL72995	Alpha-2C adrenergic receptor					 832					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213345&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44312036	376070925		CHEMBL72995					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564032	Clc1c(NC2=NCCN2)ccc2nccnc12	InChI=1S/C11H10ClN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	VJQWCCBDYLTRPZ-UHFFFAOYSA-N	50213348	CHEMBL72753	Alpha-2C adrenergic receptor					 31					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213348&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3086326	376070928		CHEMBL72753					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564033	Brc1c(NC2=NCCN2)ccc2NCCNc12	InChI=1S/C11H14BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-2,13-14H,3-6H2,(H2,15,16,17)	CETMNKCDAHCKRC-UHFFFAOYSA-N	50213028	CHEMBL74283	Alpha-2C adrenergic receptor		 214								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213028	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213028&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			131829	376070773		CHEMBL74283					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564038	Brc1c(NC2=NCCS2)ccc2nccnc12	InChI=1S/C11H9BrN4S/c12-9-7(16-11-15-5-6-17-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H,15,16)	KSVHJUZGYJOCLG-UHFFFAOYSA-N	50213350	CHEMBL73392	Alpha-2C adrenergic receptor		 28184								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213350&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44312037	376070930		CHEMBL73392					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564040	Cc1c(ccc2nccnc12)N=C1NCCN1	InChI=1S/C12H13N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-5H,6-7H2,1H3,(H2,15,16,17)	QZUXRMOPAGPTIY-UHFFFAOYSA-N	50052880	CHEMBL49137::Imidazolidin-2-ylidene-(5-methyl-quinoxalin-6-yl)-amine	Alpha-2C adrenergic receptor					 14					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052880&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			185076	103949620		CHEMBL49137				ZINC05159693	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50532146	CCN(CC)C(=O)[C@H]1CN[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34	InChI=1S/C19H23N3O/c1-3-22(4-2)19(23)13-8-15-14-6-5-7-16-18(14)12(10-20-16)9-17(15)21-11-13/h5-8,10,13,17,20-21H,3-4,9,11H2,1-2H3/t13-,17-/m1/s1	SUXLVXOMPKZBOV-CXAGYDPISA-N	50299166	(6aR,9R)-N,N-diethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide::4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid diethylamide::CHEMBL21343	Alpha-2C adrenergic receptor			>10000							ChEMBL	10.1016/j.bmcl.2009.09.002	10.7270/Q2VX0GJN	19783143			Thoma, G; Baenteli, R; Lewis, I; Wagner, T; Oberer, L; Blum, W; Glickman, F; Streiff, MB; Zerwes, HG	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299166	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299166&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			169713	104140695		CHEMBL21343				ZINC05845906	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50532148	CCN(CC)C(=O)[C@H]1CN([C@@H]2Cc3c[nH]c4cccc(C2=C1)c34)C(=O)Nc1ccccc1	InChI=1S/C26H28N4O2/c1-3-29(4-2)25(31)18-13-21-20-11-8-12-22-24(20)17(15-27-22)14-23(21)30(16-18)26(32)28-19-9-6-5-7-10-19/h5-13,15,18,23,27H,3-4,14,16H2,1-2H3,(H,28,32)/t18-,23-/m1/s1	QIPWTYSOANVUKJ-WZONZLPQSA-N	50299165	(6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide::CHEMBL584554	Alpha-2C adrenergic receptor			 215							ChEMBL	10.1016/j.bmcl.2009.09.002	10.7270/Q2VX0GJN	19783143			Thoma, G; Baenteli, R; Lewis, I; Wagner, T; Oberer, L; Blum, W; Glickman, F; Streiff, MB; Zerwes, HG	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299165	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299165&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45482789	104140694		CHEMBL584554				ZINC34837617	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50544103	CN(C)Cc1nc(-c2ccc(cc2)C(C)(C)C)n(n1)-c1cccc(O)c1	InChI=1S/C21H26N4O/c1-21(2,3)16-11-9-15(10-12-16)20-22-19(14-24(4)5)23-25(20)17-7-6-8-18(26)13-17/h6-13,26H,14H2,1-5H3	ILPANLYEJQKXKY-UHFFFAOYSA-N	50304075	3-(5-(4-tert-butylphenyl)-3-((dimethylamino)methyl)-1H-1,2,4-triazol-1-yl)phenol::CHEMBL595449	Alpha-2C adrenergic receptor			>10000							ChEMBL	10.1016/j.bmc.2009.07.007	10.7270/Q2QZ2B14	19646882			Peng, Y; Zhang, Q; Arora, S; Keenan, SM; Kortagere, S; Wannemacher, KM; Howells, RD; Welsh, WJ	University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School and the Informatics Institute of UMDNJ	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304075	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304075&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11957735	104158436		CHEMBL595449				ZINC45350099	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50546993	OC12C3C4C5C3C(C3C5CC4C13)N2CCc1cccc(F)c1	InChI=1S/C19H20FNO/c20-9-3-1-2-8(6-9)4-5-21-18-14-10-7-11-13-12(10)15(18)17(13)19(21,22)16(11)14/h1-3,6,10-18,22H,4-5,7H2	FYGREZKTJIXWIH-UHFFFAOYSA-N	50305342	4-(3'-Fluorophenethyl)-4-azahexacyclo[5.4.1.02,6.03,10.05,9.08,11]dodecan-3-ol::CHEMBL602850	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2009.11.019	10.7270/Q2NS0V0S	19954972			Banister, SD; Moussa, IA; Jordan, MJ; Coster, MJ; Kassiou, M	University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10040286	104159703		CHEMBL602850					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50546994	OC12C3C4C5C3C(C3C5CC4C13)N2Cc1cccc(F)c1	InChI=1S/C18H18FNO/c19-8-3-1-2-7(4-8)6-20-17-13-9-5-10-12-11(9)14(17)16(12)18(20,21)15(10)13/h1-4,9-17,21H,5-6H2	DUZFRLZTNIIHKJ-UHFFFAOYSA-N	50305343	4-(3'-Fluorophenyl)methyl-4-azahexacyclo[5.4.1.02,6.03,10.05,9.08,11]dodecan-3-ol::CHEMBL608560	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2009.11.019	10.7270/Q2NS0V0S	19954972			Banister, SD; Moussa, IA; Jordan, MJ; Coster, MJ; Kassiou, M	University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305343&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10356463	104159704		CHEMBL608560					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50547004	Fc1cccc(CCNC23OC4C5C6C(C25)C2CC6C4C32)c1	InChI=1S/C19H20FNO/c20-9-3-1-2-8(6-9)4-5-21-19-16-11-7-10-12-13(11)17(19)15(12)18(22-19)14(10)16/h1-3,6,10-18,21H,4-5,7H2	CWYDYWFZPBTTIM-UHFFFAOYSA-N	50305341	8-(3'-Fluorophenethyl)amino-4-oxapentacyclo[5.4.1.02,6.03,10.05,9.08,11]dodecane::CHEMBL590615	Alpha-2C adrenergic receptor		 20								ChEMBL	10.1016/j.bmcl.2009.11.019	10.7270/Q2NS0V0S	19954972			Banister, SD; Moussa, IA; Jordan, MJ; Coster, MJ; Kassiou, M	University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305341&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46225029	104159702		CHEMBL590615					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50532263	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50203564	(1R,2S,4aR,13bS,14aS)-2-hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester hydrochloride::CHEMBL537669::Yohimbine Hydrochloride::cid_6169	Alpha-2C adrenergic receptor			 27.1							ChEMBL	10.1021/jm900458r	10.7270/Q2MG7PJ4	19788200			Biancalani, C; Giovannoni, MP; Pieretti, S; Cesari, N; Graziano, A; Vergelli, C; Cilibrizzi, A; Di Gianuario, A; Colucci, M; Mangano, G; Garrone, B; Polenzani, L; Dal Piaz, V	Dipartimento di Scienze Farmaceutiche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203564&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438146	104082645		CHEMBL537669	DB01392		C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50559533	COc1ccc(cc1)-c1c(C#N)c(nn1-c1ccccc1I)C(=O)NN1CCCCC1	InChI=1S/C23H22IN5O2/c1-31-17-11-9-16(10-12-17)22-18(15-25)21(23(30)27-28-13-5-2-6-14-28)26-29(22)20-8-4-3-7-19(20)24/h3-4,7-12H,2,5-6,13-14H2,1H3,(H,27,30)	WGIPGQAPFNVWIX-UHFFFAOYSA-N	50311076	CHEMBL1079079::[125I]1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxylate	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2009.08.092	10.7270/Q23J3D3H	19767206			Donohue, SR; Varnas, K; Jia, Z; Gulyas, B; Pike, VW; Halldin, C	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50311076	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50311076&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44603087	104145437		CHEMBL1079079				ZINC49774599	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50594073	Oc1ccc2[C@@H]3CNCC[C@H]3[C@@H](Cc2c1O)c1ccccc1	InChI=1S/C19H21NO2/c21-18-7-6-13-16(19(18)22)10-15(12-4-2-1-3-5-12)14-8-9-20-11-17(13)14/h1-7,14-15,17,20-22H,8-11H2/t14-,15-,17-/m0/s1	FKYWSGYMKJUZEP-ZOBUZTSGSA-N	50325822	CHEMBL1224527::trans-(5R)-5-phenyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[h]isoquinoline-7,8-diol	Alpha-2C adrenergic receptor		 1100								ChEMBL	10.1016/j.bmc.2010.07.052	10.7270/Q29K4BFR	20709559			Bonner, LA; Chemel, BR; Watts, VJ; Nichols, DE	Purdue University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325822&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46869265	117647143		CHEMBL1224527				ZINC58581107	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50598631	C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21	InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1	CKLPLPZSUQEDRT-WPCRTTGESA-N	50318666	(1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-tetrahydrospiro-[beta-carboline-1,3'-indol]-2'(1'H)-one::CHEMBL1082723::NITD609	Alpha-2C adrenergic receptor			>10000							ChEMBL	10.1126/science.1193225	10.7270/Q2SB45ZB	20813948			Rottmann, M; McNamara, C; Yeung, BK; Lee, MC; Zou, B; Russell, B; Seitz, P; Plouffe, DM; Dharia, NV; Tan, J; Cohen, SB; Spencer, KR; Gonzalez-Paez, GE; Lakshminarayana, SB; Goh, A; Suwanarusk, R; Jegla, T; Schmitt, EK; Beck, HP; Brun, R; Nosten, F; Renia, L; Dartois, V; Keller, TH; Fidock, DA; Winzeler, EA; Diagana, TT	Swiss Tropical and Public Health Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50318666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50318666&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44469321	104153027		CHEMBL1082723				ZINC49037032	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50581866	CN1CC2[C@H](CN3CCN(C\C=C\c4ccccc4)CC3)ON=C2c2ccccc12	InChI=1S/C25H30N4O/c1-27-18-22-24(30-26-25(22)21-11-5-6-12-23(21)27)19-29-16-14-28(15-17-29)13-7-10-20-8-3-2-4-9-20/h2-12,22,24H,13-19H2,1H3/b10-7+/t22?,24-/m0/s1	GHPKBFZQNLPFFZ-BIGUYTSMSA-N	50320446	CHEMBL1085510::[N-methyl]5-methyl-3-[4-(3-phenylallyl)-piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroisoxazolo[4,3-c]quinoline	Alpha-2C adrenergic receptor		 4.5								ChEMBL	10.1016/j.bmcl.2010.04.099	10.7270/Q2474B1C	20529687			Prabhakaran, J; Majo, VJ; Milak, MS; Mali, P; Savenkova, L; Mann, JJ; Parsey, RV; Kumar, JS	Columbia University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320446&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			46891598	104141975		CHEMBL1085510				ZINC49115356	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50601662	CCCCN1CCC(COC(=O)c2cc(Cl)c(NC)c3OCCOc23)CC1	InChI=1S/C20H29ClN2O4/c1-3-4-7-23-8-5-14(6-9-23)13-27-20(24)15-12-16(21)17(22-2)19-18(15)25-10-11-26-19/h12,14,22H,3-11,13H2,1-2H3	WKWADEWWLCVVLF-UHFFFAOYSA-N	50327860	(1-Butylpiperidin-4-yl)methyl 7-chloro-8-(methylamino)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate::CHEMBL1258223	Alpha-2C adrenergic receptor		 556								ChEMBL	10.1021/jm100668r	10.7270/Q2BR8SD7	20812727			Xu, R; Hong, J; Morse, CL; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50327860	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50327860&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49783209	123106975		CHEMBL1258223				ZINC64548813	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50601705	CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1	InChI=1S/C18H28N2O3/c1-3-4-9-20-10-7-14(8-11-20)13-23-18(21)15-5-6-16(19)17(12-15)22-2/h5-6,12,14H,3-4,7-11,13,19H2,1-2H3	DZZIAERGLDKTBT-UHFFFAOYSA-N	50327861	(1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxybenzoate::CHEMBL1258452	Alpha-2C adrenergic receptor		 989								ChEMBL	10.1021/jm100668r	10.7270/Q2BR8SD7	20812727			Xu, R; Hong, J; Morse, CL; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50327861	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50327861&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49783415	123106976		CHEMBL1258452				ZINC64548966	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50601713	CCCCN1CCC(COC(=O)c2cc(F)c(N)c3OCCOc23)CC1	InChI=1S/C19H27FN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3	WLHFUBIRAHRPHA-UHFFFAOYSA-N	50327863	(1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate::CHEMBL1258671	Alpha-2C adrenergic receptor		 593								ChEMBL	10.1021/jm100668r	10.7270/Q2BR8SD7	20812727			Xu, R; Hong, J; Morse, CL; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50327863	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50327863&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49783419	123106978		CHEMBL1258671				ZINC64548828	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50617217	CN(CCc1cccc(F)c1)[C@@H]1C2C3CC4C5CC(C2C35)C14	InChI=1S/C20H24FN/c1-22(6-5-10-3-2-4-11(21)7-10)20-17-13-9-14-16-12(13)8-15(17)18(16)19(14)20/h2-4,7,12-20H,5-6,8-9H2,1H3/t12?,13?,14?,15?,16?,17?,18?,19?,20-/m0/s1	LGZPNSXZRKGUES-DKSPCFMDSA-N	50334456	CHEMBL1643902::N-(2-(3'-Fluorophenyl)ethyl)-N-methyl-8-aminopentacyclo[5.4.0.02,6.03,10.05,9]undecane	Alpha-2C adrenergic receptor		 2071								ChEMBL	10.1016/j.bmcl.2010.11.075	10.7270/Q20K28VR	21146989			Banister, SD; Moussa, IA; Beinat, C; Reynolds, AJ; Schiavini, P; Jorgensen, WT; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334456	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334456&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53325861	125084558		CHEMBL1643902					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50583530	CN(CC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1)CC([O-])=O	InChI=1S/C19H20F3NO3/c1-23(13-18(24)25)12-11-17(14-5-3-2-4-6-14)26-16-9-7-15(8-10-16)19(20,21)22/h2-10,17H,11-13H2,1H3,(H,24,25)/p-1/t17-/m1/s1	KZWQAWBTWNPFPW-QGZVFWFLSA-M	50421506	CHEMBL61861::ORG-24598	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/s0960-894x(01)00355-9	10.7270/Q2X0687Q	11454468			Brown, A; Carlyle, I; Clark, J; Hamilton, W; Gibson, S; McGarry, G; McEachen, S; Rae, D; Thorn, S; Walker, G	Organon Research and Development Group	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421506&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16759590	164150381		CHEMBL61861					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50714451	Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ncccn1	InChI=1S/C18H21FN4O/c19-16-6-4-15(5-7-16)17(24)3-1-10-22-11-13-23(14-12-22)18-20-8-2-9-21-18/h2,4-9H,1,3,10-14H2	WEVJMQOBCRCIPF-UHFFFAOYSA-N	50002334	1-(4-Fluoro-phenyl)-4-(4-pyrimidin-2-yl-piperazin-1-yl)-butan-1-one::4-[4-(2-Pyrimidine)piperazin-1-yl]-1-(4-fluorophenyl)-butan-1-one::CHEMBL140872	Alpha-2C adrenergic receptor		 80								ChEMBL	10.1016/j.bmc.2011.12.019	10.7270/Q2Q52Q26	22245230			Peprah, K; Zhu, XY; Eyunni, SV; Setola, V; Roth, BL; Ablordeppey, SY	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002334	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002334&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10065083	103916640		CHEMBL140872				ZINC13730842	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50714452	Fc1ccc(CCCCN2CCN(CC2)c2ccccn2)cc1	InChI=1S/C19H24FN3/c20-18-9-7-17(8-10-18)5-2-4-12-22-13-15-23(16-14-22)19-6-1-3-11-21-19/h1,3,6-11H,2,4-5,12-16H2	NSMCYUMPIGJKHV-UHFFFAOYSA-N	50362863	CHEMBL1940418	Alpha-2C adrenergic receptor		 308.2								ChEMBL	10.1016/j.bmc.2011.12.019	10.7270/Q2Q52Q26	22245230			Peprah, K; Zhu, XY; Eyunni, SV; Setola, V; Roth, BL; Ablordeppey, SY	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362863	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362863&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44209480	136966925		CHEMBL1940418				ZINC43211125	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50714453	Fc1ccc(SCCCN2CCN(CC2)c2ccccn2)cc1	InChI=1S/C18H22FN3S/c19-16-5-7-17(8-6-16)23-15-3-10-21-11-13-22(14-12-21)18-4-1-2-9-20-18/h1-2,4-9H,3,10-15H2	IESJRUUOIHDONG-UHFFFAOYSA-N	50362864	CHEMBL1940419	Alpha-2C adrenergic receptor		 45.1								ChEMBL	10.1016/j.bmc.2011.12.019	10.7270/Q2Q52Q26	22245230			Peprah, K; Zhu, XY; Eyunni, SV; Setola, V; Roth, BL; Ablordeppey, SY	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362864	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362864&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57401706	136966926		CHEMBL1940419				ZINC73222863	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50714454	Fc1ccc(OCCCN2CCN(CC2)c2ccccn2)cc1	InChI=1S/C18H22FN3O/c19-16-5-7-17(8-6-16)23-15-3-10-21-11-13-22(14-12-21)18-4-1-2-9-20-18/h1-2,4-9H,3,10-15H2	BPDDCCYSOYRMEC-UHFFFAOYSA-N	50362865	CHEMBL1940420	Alpha-2C adrenergic receptor		 194.5								ChEMBL	10.1016/j.bmc.2011.12.019	10.7270/Q2Q52Q26	22245230			Peprah, K; Zhu, XY; Eyunni, SV; Setola, V; Roth, BL; Ablordeppey, SY	Florida A&M University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362865	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362865&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44209472	136966927		CHEMBL1940420				ZINC60992916	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50729589	CCC1=NC(COCCCN)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C39H48N6O5/c1-2-32-35(37(41)46)34(28-15-17-31(18-16-28)45(48)49)36(33(43-32)27-50-26-9-21-40)38(47)42-22-10-23-44-24-19-39(20-25-44,29-11-5-3-6-12-29)30-13-7-4-8-14-30/h3-8,11-18,34-35H,2,9-10,19-27,40H2,1H3,(H2,41,46)(H,42,47)	UTCOMQXMXQJEDA-UHFFFAOYSA-N	50081823	2-(3-Amino-propoxymethyl)-6-ethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-amide 3-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL95578	Alpha-2C adrenergic receptor		 286								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081823&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931166	103981762		CHEMBL95578				ZINC26725039	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50729596	CC1=NC(C)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H41N5O4/c1-25-31(34(37)42)33(27-15-17-30(18-16-27)41(44)45)32(26(2)39-25)35(43)38-21-9-10-22-40-23-19-36(20-24-40,28-11-5-3-6-12-28)29-13-7-4-8-14-29/h3-8,11-18,31,33H,9-10,19-24H2,1-2H3,(H2,37,42)(H,38,43)	SQEOIKNCNRHYGE-UHFFFAOYSA-N	50160146	2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[4-(4,4-diphenyl-piperidin-1-yl)-butyl]-amide}::CHEMBL180561	Alpha-2C adrenergic receptor		 324								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160146&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91933253	104046706		CHEMBL180561				ZINC28342210	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50729601	CCC1=NC(CCCCOC)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C40H49N5O5/c1-3-33-36(38(41)46)35(29-18-20-32(21-19-29)45(48)49)37(34(43-33)17-10-11-28-50-2)39(47)42-24-12-25-44-26-22-40(23-27-44,30-13-6-4-7-14-30)31-15-8-5-9-16-31/h4-9,13-16,18-21,35-36H,3,10-12,17,22-28H2,1-2H3,(H2,41,46)(H,42,47)	NSXUBFCOCMDGJL-UHFFFAOYSA-N	50081817	2-Ethyl-6-(4-methoxy-butyl)-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL99864	Alpha-2C adrenergic receptor		 355								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081817&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931161	103981756		CHEMBL99864				ZINC26735766	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50729602	COC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H40N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-15-17-30(18-16-27)40(43)44)34(41)37-21-10-22-39-23-19-36(20-24-39,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,32-33H,10,19-24H2,1-3H3,(H,37,41)	PQRXHDGVJRPPSF-UHFFFAOYSA-N	50366618	CHEMBL448620::SNAP-5089	Alpha-2C adrenergic receptor		 912								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366618&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54203251	160845720		CHEMBL448620				ZINC28759802	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50729626	CCC1=NC(COCCN=[N+]=[N-])=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C38H44N8O5/c1-2-31-34(36(39)47)33(27-14-16-30(17-15-27)46(49)50)35(32(43-31)26-51-25-21-42-44-40)37(48)41-20-9-22-45-23-18-38(19-24-45,28-10-5-3-6-11-28)29-12-7-4-8-13-29/h3-8,10-17,33-34H,2,9,18-26H2,1H3,(H2,39,47)(H,41,48)	RUEVDDMZSNRBBA-UHFFFAOYSA-N	50081824	2-(2-Azido-ethoxymethyl)-6-ethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-amide 3-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL98063	Alpha-2C adrenergic receptor		 224								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081824&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931167	103981763		CHEMBL98063				ZINC26717909	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50729637	CCCC1=C(C(C(C(=O)NCC)C(CC)=N1)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C40H49N5O4/c1-4-14-34-37(35(29-19-21-32(22-20-29)45(48)49)36(33(5-2)43-34)38(46)41-6-3)39(47)42-25-13-26-44-27-23-40(24-28-44,30-15-9-7-10-16-30)31-17-11-8-12-18-31/h7-12,15-22,35-36H,4-6,13-14,23-28H2,1-3H3,(H,41,46)(H,42,47)	QQBCCUCHUBUQEQ-UHFFFAOYSA-N	50081819	2-Ethyl-4-(4-nitro-phenyl)-6-propyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide} 3-ethylamide::CHEMBL316495	Alpha-2C adrenergic receptor		 442								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081819	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081819&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931162	103981758		CHEMBL316495				ZINC26717919	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50729658	CCNC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(COCCN)N=C1CC)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C40H50N6O5/c1-3-33-36(38(47)42-4-2)35(29-16-18-32(19-17-29)46(49)50)37(34(44-33)28-51-27-22-41)39(48)43-23-11-24-45-25-20-40(21-26-45,30-12-7-5-8-13-30)31-14-9-6-10-15-31/h5-10,12-19,35-36H,3-4,11,20-28,41H2,1-2H3,(H,42,47)(H,43,48)	GZYMKAZAURLMJX-UHFFFAOYSA-N	50081826	2-(2-Amino-ethoxymethyl)-6-ethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide} 5-ethylamide::CHEMBL95290	Alpha-2C adrenergic receptor		 473								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081826&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931169	103981765		CHEMBL95290				ZINC26725927	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50729674	CCC1=NC(COCC(F)(F)F)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C38H42F3N5O5/c1-2-30-33(35(42)47)32(26-14-16-29(17-15-26)46(49)50)34(31(44-30)24-51-25-38(39,40)41)36(48)43-20-9-21-45-22-18-37(19-23-45,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-17,32-33H,2,9,18-25H2,1H3,(H2,42,47)(H,43,48)	NFZNWSQRGYZNCQ-UHFFFAOYSA-N	50081828	2-Ethyl-4-(4-nitro-phenyl)-6-(2,2,2-trifluoro-ethoxymethyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL320736	Alpha-2C adrenergic receptor		 884								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081828&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931171	103981767		CHEMBL320736				ZINC26726005	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50729677	CCC1=NC(COC)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C37H43N5O5/c1-3-30-33(35(38)43)32(26-15-17-29(18-16-26)42(45)46)34(31(40-30)25-47-2)36(44)39-21-10-22-41-23-19-37(20-24-41,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-18,32-33H,3,10,19-25H2,1-2H3,(H2,38,43)(H,39,44)	SPIJYUMJUFXBOQ-UHFFFAOYSA-N	50081821	2-Ethyl-6-methoxymethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL100045	Alpha-2C adrenergic receptor		 513								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081821	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081821&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931164	103981760		CHEMBL100045				ZINC26734616	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50729680	CCC1=NC(COCCN)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C38H46N6O5/c1-2-31-34(36(40)45)33(27-14-16-30(17-15-27)44(47)48)35(32(42-31)26-49-25-20-39)37(46)41-21-9-22-43-23-18-38(19-24-43,28-10-5-3-6-11-28)29-12-7-4-8-13-29/h3-8,10-17,33-34H,2,9,18-26,39H2,1H3,(H2,40,45)(H,41,46)	XIIKDAODIFECTH-UHFFFAOYSA-N	50081818	2-(2-Amino-ethoxymethyl)-6-ethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-amide 3-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL323579	Alpha-2C adrenergic receptor		 204								ChEMBL	10.1016/s0960-894x(99)00484-9	10.7270/Q2NK3FJ2	10522703			Marzabadi, MR; Hong, X; Nagarathnam, D; Miao, SW; Chiu, G; Wong, WC; Wetzel, JM; Fang, J; Forray, C; Chen, TB; O'Malley, SS; Chang, RS; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081818&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91518586	103981757		CHEMBL323579				ZINC26724522	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50735442	COc1ccccc1N1CCN(CCn2c(=O)[nH]c3scc(-c4ccccc4)c3c2=O)CC1	InChI=1S/C25H26N4O3S/c1-32-21-10-6-5-9-20(21)28-14-11-27(12-15-28)13-16-29-24(30)22-19(18-7-3-2-4-8-18)17-33-23(22)26-25(29)31/h2-10,17H,11-16H2,1H3,(H,26,31)	HLVQBOYEHQRWHG-UHFFFAOYSA-N	50099322	3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-5-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione::A-119637::CHEMBL268758	Alpha-2C adrenergic receptor		 75								ChEMBL	10.1016/s0960-894x(01)00159-7	10.7270/Q20V8DBQ	11354357			Carroll, WA; Sippy, KB; Esbenshade, TA; Buckner, SA; Hancock, AA; Meyer, MD	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099322	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099322&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9890547	103996238		CHEMBL268758		490		ZINC01487800	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50735446	COc1ccccc1N1CCN(CCn2c(=O)[nH]c3scc(-c4cccc(C)c4)c3c2=O)CC1	InChI=1S/C26H28N4O3S/c1-18-6-5-7-19(16-18)20-17-34-24-23(20)25(31)30(26(32)27-24)15-12-28-10-13-29(14-11-28)21-8-3-4-9-22(21)33-2/h3-9,16-17H,10-15H2,1-2H3,(H,27,32)	PANBMHHKBRMYAL-UHFFFAOYSA-N	50099325	3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-5-m-tolyl-1H-thieno[2,3-d]pyrimidine-2,4-dione::A-123189::CHEMBL13856	Alpha-2C adrenergic receptor		 82								ChEMBL	10.1016/s0960-894x(01)00159-7	10.7270/Q20V8DBQ	11354357			Carroll, WA; Sippy, KB; Esbenshade, TA; Buckner, SA; Hancock, AA; Meyer, MD	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099325	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099325&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9891167	103996241		CHEMBL13856		491		ZINC34014527	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50779611	COc1nc(C)nc(Cl)c1N=C1NCCN1	InChI=1S/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,1-2H3,(H2,11,12,15)	WPNJAUFVNXKLIM-UHFFFAOYSA-N	50050093	(4-Chloro-6-methoxy-2-methyl-pyrimidin-5-yl)-imidazolidin-2-ylidene-amine::2-(4-Chloro-6-methoxy-2-methyl-pyrimidin-5-ylamino)-4,5-dihydro-3H-imidazol-1-ium::CHEMBL19236::MOXONIDINE	Alpha-2C adrenergic receptor		 2000								ChEMBL	10.1021/jm960012o	10.7270/Q2NZ889J	8632424			Munk, SA; Lai, RK; Burke, JE; Arasasingham, PN; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Wijono, MK; Hasson, DW; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050093	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050093&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4810	103947280		CHEMBL19236				ZINC01854466	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50779613	CC(C)C1C2CCC(C2)C1N	InChI=1S/C10H19N/c1-6(2)9-7-3-4-8(5-7)10(9)11/h6-10H,3-5,11H2,1-2H3	SHXVJSFOJHMEEQ-UHFFFAOYSA-N	50050094	3-Isopropyl-bicyclo[2.2.1]hept-2-ylamine::CHEMBL430112	Alpha-2C adrenergic receptor		>20000								ChEMBL	10.1021/jm960012o	10.7270/Q2NZ889J	8632424			Munk, SA; Lai, RK; Burke, JE; Arasasingham, PN; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Wijono, MK; Hasson, DW; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050094&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2068	103947281		CHEMBL430112				ZINC03871453	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50779615	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2C adrenergic receptor		 30								ChEMBL	10.1021/jm960012o	10.7270/Q2NZ889J	8632424			Munk, SA; Lai, RK; Burke, JE; Arasasingham, PN; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Wijono, MK; Hasson, DW; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50779618	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2C adrenergic receptor		 63								ChEMBL	10.1021/jm960012o	10.7270/Q2NZ889J	8632424			Munk, SA; Lai, RK; Burke, JE; Arasasingham, PN; Kharlamb, AB; Manlapaz, CA; Padillo, EU; Wijono, MK; Hasson, DW; Wheeler, LA; Garst, ME	Allergan Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773143	CNC(=O)c1c(C)nc(C)c(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)c1-c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H39N5O4/c1-25-31(34(42)37-3)33(27-15-17-30(18-16-27)41(44)45)32(26(2)39-25)35(43)38-21-10-22-40-23-19-36(20-24-40,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18H,10,19-24H2,1-3H3,(H,37,42)(H,38,43)	HCBLAAMIRQXAHR-UHFFFAOYSA-N	50030613	2,6-Dimethyl-4-(4-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide} 5-methylamide::CHEMBL125294	Alpha-2C adrenergic receptor		 323								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030613&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44348028	103939462		CHEMBL125294				ZINC27207228	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773144	CN1CCc2c(Cl)ccc3sc(C=C)c(C1)c23	InChI=1S/C14H14ClNS/c1-3-12-10-8-16(2)7-6-9-11(15)4-5-13(17-12)14(9)10/h3-5H,1,6-8H2,2H3	WKXSXFYQPCWZOS-UHFFFAOYSA-N	50030614	5-Chloro-8-methyl-1-vinyl-6,7,8,9-tetrahydro-2-thia-8-aza-benzo[cd]azulene::CHEMBL25467::SK&F-104856::SK-104856::SKF 104856	Alpha-2C adrenergic receptor		 21								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030614&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			126225	103939463		CHEMBL25467				ZINC28758641	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773147	Cc1nc(C)c(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)c(-c2ccc(cc2)[N+]([O-])=O)c1C(N)=O	InChI=1S/C35H37N5O4/c1-24-30(33(36)41)32(26-14-16-29(17-15-26)40(43)44)31(25(2)38-24)34(42)37-20-9-21-39-22-18-35(19-23-39,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-17H,9,18-23H2,1-2H3,(H2,36,41)(H,37,42)	XAFOTAKURAOBIE-UHFFFAOYSA-N	50030617	2,6-Dimethyl-4-(4-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL122671	Alpha-2C adrenergic receptor		 165								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030617&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44348045	103939466		CHEMBL122671				ZINC27195359	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773155	COC(=O)C1=CO[C@@H](C)[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16+,19-/m0/s1	GRTOGORTSDXSFK-XJTZBENFSA-N	50030612	(7aR,8S,11aS,12aS)-8-Methyl-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester::CHEMBL123325::RAUWOLFIA SERPENTINA ROOT::ajmalicine	Alpha-2C adrenergic receptor		 5								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030612	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030612&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	AJN	4WNT	441975	103939461		CHEMBL123325			C09024		1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773164	CN1CCc2c(Cl)ccc3oc(Br)c(C1)c23	InChI=1S/C12H11BrClNO/c1-15-5-4-7-9(14)2-3-10-11(7)8(6-15)12(13)16-10/h2-3H,4-6H2,1H3	NYGANYRUZQPPGP-UHFFFAOYSA-N	50030619	1-Bromo-5-chloro-8-methyl-6,7,8,9-tetrahydro-2-oxa-8-aza-benzo[cd]azulene::CHEMBL123138::SK&F-105854::SK-105854	Alpha-2C adrenergic receptor		 28								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030619&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9839317	103939468		CHEMBL123138		518		ZINC27197433	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773167	CN1CCc2cccc(Cl)c2CC1	InChI=1S/C11H14ClN/c1-13-7-5-9-3-2-4-11(12)10(9)6-8-13/h2-4H,5-8H2,1H3	RSRUDTPYRBLHEO-UHFFFAOYSA-N	66983	6-chloranyl-3-methyl-1,2,4,5-tetrahydro-3-benzazepine;hydrochloride::6-chloro-3-methyl-1,2,4,5-tetrahydro-3-benzazepine;hydrochloride::CHEMBL123349::MLS002172470::SKF 86466::SKF-86466 hydrochloride::SMR001254100::cid_10220250	Alpha-2C adrenergic receptor		 20								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66983	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66983&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			123981	252645294		CHEMBL123349			C10970	ZINC00900633	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50771433	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1	InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)	VCKUSRYTPJJLNI-UHFFFAOYSA-N	50033111	1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine::6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine::CHEMBL611::TERAZOSIN::Terazosine	Alpha-2C adrenergic receptor		 170								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033111&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TZN	4O3F,4O33	5401	103941452	9445	CHEMBL611	DB01162	7302	C07127	ZINC01271441	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50771442	COC(=[OH+])C1=C(C)N=C(C)C(C1c1ccc(cc1)[N+]([O-])=O)=C([O-])OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H39N3O6/c1-25-31(34(40)44-3)33(27-15-17-30(18-16-27)39(42)43)32(26(2)37-25)35(41)45-24-10-21-38-22-19-36(20-23-38,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,33,41H,10,19-24H2,1-3H3	ISZKYBBFFMQCLL-UHFFFAOYSA-N	50034681	2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-[3-(4,4-diphenyl-piperidin-1-yl)-propyl] ester 5-methyl ester::CHEMBL290860	Alpha-2C adrenergic receptor		 300								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034681&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9960497	103942846		CHEMBL290860				ZINC29341039	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773186	CCc1sc2ccc(Cl)c3CCN(C)Cc1c23	InChI=1S/C14H16ClNS/c1-3-12-10-8-16(2)7-6-9-11(15)4-5-13(17-12)14(9)10/h4-5H,3,6-8H2,1-2H3	BAAUEDJUTZLMAN-UHFFFAOYSA-N	50030615	5-Chloro-1-ethyl-8-methyl-6,7,8,9-tetrahydro-2-thia-8-aza-benzo[cd]azulene::CHEMBL123448::SK&F-106686::SK-106686	Alpha-2C adrenergic receptor		 35								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030615&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10946567	103939464		CHEMBL123448				ZINC27197425	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773187	COC(=O)c1c(C)nc(C)c(C(=O)OCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)c1-c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H37N3O6/c1-25-31(34(40)44-3)33(27-15-17-30(18-16-27)39(42)43)32(26(2)37-25)35(41)45-24-10-21-38-22-19-36(20-23-38,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18H,10,19-24H2,1-3H3	BXERZGFRIILESM-UHFFFAOYSA-N	50030624	2,6-Dimethyl-4-(4-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-[3-(4,4-diphenyl-piperidin-1-yl)-propyl] ester 5-methyl ester::CHEMBL123769	Alpha-2C adrenergic receptor		 1700								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030624&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44348163	103939473		CHEMBL123769				ZINC27197813	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773189	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2C adrenergic receptor		 2.3								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773200	COC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H40N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-15-17-30(18-16-27)40(43)44)34(41)37-21-10-22-39-23-19-36(20-24-39,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,32-33H,10,19-24H2,1-3H3,(H,37,41)	PQRXHDGVJRPPSF-UHFFFAOYSA-N	50366618	CHEMBL448620::SNAP-5089	Alpha-2C adrenergic receptor		 1320								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366618&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54203251	160845720		CHEMBL448620				ZINC28759802	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773204	COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17+,18+,19+/m1/s1	BLGXFZZNTVWLAY-DIRVCLHFSA-N	50026636	17alpha-hydroxy-20alpha-yohimban-16beta-carboxylic acid methyl ester::CHEMBL10347::RAUWOLSCINE HYDROCHLORIDE::alpha-yohimbine::corynanthidine::isoyohimbine::mesoyohimbine::methyl (16beta,17alpha,20alpha)-17-hydroxyyohimban-16-carboxylate::methyl 17alpha-hydroxy-20alpha-yohimban-16beta-carboxylate::rauwolscine	Alpha-2C adrenergic receptor		 1								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026636&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			643606	103936228	48565	CHEMBL10347				ZINC03977785	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773206	COC(=O)c1c(C)nc(C)c(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)c1-c1cccc(c1)[N+]([O-])=O	InChI=1S/C36H38N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-12-10-17-30(24-27)40(43)44)34(41)37-20-11-21-39-22-18-36(19-23-39,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24H,11,18-23H2,1-3H3,(H,37,41)	LQIROCVOCINDLE-UHFFFAOYSA-N	50030621	5-[3-(4,4-Diphenyl-piperidin-1-yl)-propylcarbamoyl]-2,6-dimethyl-4-(3-nitro-phenyl)-nicotinic acid methyl ester::CHEMBL123102	Alpha-2C adrenergic receptor		 560								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030621&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44348164	103939470		CHEMBL123102				ZINC27197822	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773217	COC(=O)[C@@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19-/m0/s1	BLGXFZZNTVWLAY-DKJBZYCGSA-N	50027058	(1S,2S,4aR,13bS,14aS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2'',3'':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester::(1S,2S,4aR,13bS,14aS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester::2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester::CHEMBL31410::corynantheine	Alpha-2C adrenergic receptor		 161								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027058&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			92766	103936640	48565	CHEMBL31410		5345		ZINC03861548	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773247	COC(=O)C1=CO[C@@H](C)[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@H]3C[C@H]12	InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16-,19+/m0/s1	GRTOGORTSDXSFK-BMYCAMMWSA-N	50030622	(7aS,8S,11aS,12aR)-8-Methyl-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester::AKUAMMIGINE::CHEMBL122404	Alpha-2C adrenergic receptor		 28								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030622&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			1268096	103939471		CHEMBL122404				ZINC53174616	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50773254	CN1CCc2c(Cl)ccc(OCC=C(C)C)c2CC1	InChI=1S/C16H22ClNO/c1-12(2)8-11-19-16-5-4-15(17)13-6-9-18(3)10-7-14(13)16/h4-5,8H,6-7,9-11H2,1-3H3	MBYSTKNEMJZSIK-UHFFFAOYSA-N	50030623	6-Chloro-3-methyl-9-(3-methyl-but-2-enyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL114166::SK&F-104078::SK-104078::SKF 104078	Alpha-2C adrenergic receptor		 64								ChEMBL	10.1021/jm00019a001	10.7270/Q2SB46C4	7562902			Ruffolo, RR; Bondinell, W; Hieble, JP	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50030623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50030623&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122295	103939472		CHEMBL114166				ZINC05158824	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50771456	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	IENZQIKPVFGBNW-UHFFFAOYSA-N	29568	CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin	Alpha-2C adrenergic receptor		 24								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XRA	3OWX	4893	81054997	8364	CHEMBL2	DB00457	503	C07368	ZINC00601304	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50771461	COC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H40N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-15-17-30(18-16-27)40(43)44)34(41)37-21-10-22-39-23-19-36(20-24-39,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,32-33H,10,19-24H2,1-3H3,(H,37,41)	PQRXHDGVJRPPSF-UHFFFAOYSA-N	50366618	CHEMBL448620::SNAP-5089	Alpha-2C adrenergic receptor		 370								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366618&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54203251	160845720		CHEMBL448620				ZINC28759802	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50771480	COC(=[OH+])C1=C(C)N=C(C)C([C@H]1c1cccc(c1)[N+]([O-])=O)=C([O-])OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H39N3O6/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24,33,41H,11,18-23H2,1-3H3/t33-/m0/s1	OCBZSBUOYIQXSP-XIFFEERXSA-N	50034683	(S)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-[3-(4,4-diphenyl-piperidin-1-yl)-propyl] ester 5-methyl ester::CHEMBL41929	Alpha-2C adrenergic receptor		 330								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034683&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			60602	103942848		CHEMBL41929		487		ZINC26384924	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50771482	COC(=[OH+])C1=C(C)N=C(C)C([C@@H]1c1cccc(c1)[N+]([O-])=O)=C([O-])OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H39N3O6/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24,33,41H,11,18-23H2,1-3H3/t33-/m1/s1	OCBZSBUOYIQXSP-MGBGTMOVSA-N	50034682	(R)-2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-[3-(4,4-diphenyl-piperidin-1-yl)-propyl] ester 5-methyl ester::CHEMBL436150::NIGULDIPINE	Alpha-2C adrenergic receptor		 450								ChEMBL	10.1021/jm00010a001	10.7270/Q25Q4WRJ	7752182			Wetzel, JM; Miao, SW; Forray, C; Borden, LA; Branchek, TA; Gluchowski, C	Synaptic Pharmaceutical Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034682&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6918097	103942847		CHEMBL436150		463		ZINC26384919	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50814570	CC(N)Cc1c[nH]c2ccc3OCCCc3c12	InChI=1S/C14H18N2O/c1-9(15)7-10-8-16-12-4-5-13-11(14(10)12)3-2-6-17-13/h4-5,8-9,16H,2-3,6-7,15H2,1H3	VVHJUSGIUWQPIT-UHFFFAOYSA-N	50133229	1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine::CHEMBL133868	Alpha-2C adrenergic receptor			>30000							ChEMBL	10.1021/jm030205t	10.7270/Q2Z320C1	12954071			May, JA; Chen, HH; Rusinko, A; Lynch, VM; Sharif, NA; McLaughlin, MA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133229&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9856041	104024141		CHEMBL133868				ZINC13527318	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50814593	C[C@H](N)Cc1c[nH]c2ccc3OCCCc3c12	InChI=1S/C14H18N2O/c1-9(15)7-10-8-16-12-4-5-13-11(14(10)12)3-2-6-17-13/h4-5,8-9,16H,2-3,6-7,15H2,1H3/t9-/m0/s1	VVHJUSGIUWQPIT-VIFPVBQESA-N	50133232	(S)-1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine::CHEMBL133455	Alpha-2C adrenergic receptor			 14000							ChEMBL	10.1021/jm030205t	10.7270/Q2Z320C1	12954071			May, JA; Chen, HH; Rusinko, A; Lynch, VM; Sharif, NA; McLaughlin, MA	Alcon Research Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133232&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10331436	104024144		CHEMBL133455		160			1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50834235	C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)\C=C\c1ccc(Cl)cc1NC(C)=O	InChI=1S/C23H25ClFN3O2/c1-16-14-27(15-18-3-8-21(25)9-4-18)11-12-28(16)23(30)10-6-19-5-7-20(24)13-22(19)26-17(2)29/h3-10,13,16H,11-12,14-15H2,1-2H3,(H,26,29)/b10-6+/t16-/m1/s1	DUFKTZBQJIHIAQ-VGZDNEPHSA-N	50174702	(R)-N-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)-5-chlorophenyl)acetamide::CHEMBL198949	Alpha-2C adrenergic receptor			>1000							ChEMBL	10.1016/j.bmcl.2005.08.057	10.7270/Q2C53MMD	16198561			Revesz, L; Bollbuck, B; Buhl, T; Eder, J; Esser, R; Feifel, R; Heng, R; Hiestand, P; Jachez-Demange, B; Loetscher, P; Sparrer, H; Schlapbach, A; Waelchli, R	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174702&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11743399	104060492		CHEMBL198949				ZINC13985934	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850279	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NCC(C)(C)N)Cc2cc1OC	InChI=1S/C26H33N3O5/c1-26(2,27)15-28-25(30)23-12-19-17(6-7-20(31-3)24(19)34-23)13-29-9-8-16-10-21(32-4)22(33-5)11-18(16)14-29/h6-7,10-12H,8-9,13-15,27H2,1-5H3,(H,28,30)	JYEPTVGXWUQMKF-UHFFFAOYSA-N	50203553	CHEMBL247664::N-(2-amino-2-methylpropyl)-4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-7-methoxybenzofuran-2-carboxamide	Alpha-2C adrenergic receptor		 4.2								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203553&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438166	104082634		CHEMBL247664				ZINC28878066	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850286	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3F)Cc2cc1OC	InChI=1S/C27H26FNO4/c1-30-23-9-8-18(21-14-24(33-27(21)23)20-6-4-5-7-22(20)28)15-29-11-10-17-12-25(31-2)26(32-3)13-19(17)16-29/h4-9,12-14H,10-11,15-16H2,1-3H3	NTHIAFXFYRUEJP-UHFFFAOYSA-N	50203554	2-((2-(2-fluorophenyl)-7-methoxybenzofuran-4-yl)methyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline::CHEMBL393597	Alpha-2C adrenergic receptor		 11								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203554&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11293787	104082635		CHEMBL393597				ZINC28877971	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850287	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3cccc(c3)C(=O)NCCN(C)C)Cc2cc1OC	InChI=1S/C32H37N3O5/c1-34(2)14-12-33-32(36)23-8-6-7-22(15-23)28-18-26-24(9-10-27(37-3)31(26)40-28)19-35-13-11-21-16-29(38-4)30(39-5)17-25(21)20-35/h6-10,15-18H,11-14,19-20H2,1-5H3,(H,33,36)	MGJOAQODMQCCGV-UHFFFAOYSA-N	50203557	3-(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-7-methoxybenzofuran-2-yl)-N-(2-(dimethylamino)ethyl)benzamide::CHEMBL392771	Alpha-2C adrenergic receptor		 9.4								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203557&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438161	104082638		CHEMBL392771				ZINC28878039	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850290	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccco3)Cc2cc1OC	InChI=1S/C25H25NO5/c1-27-21-7-6-17(19-13-24(31-25(19)21)20-5-4-10-30-20)14-26-9-8-16-11-22(28-2)23(29-3)12-18(16)15-26/h4-7,10-13H,8-9,14-15H2,1-3H3	JXCCNCOVOMQXNP-UHFFFAOYSA-N	50203559	2-((2-(furan-2-yl)-7-methoxybenzofuran-4-yl)methyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline::CHEMBL392991	Alpha-2C adrenergic receptor		 8								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203559&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11750482	104082640		CHEMBL392991				ZINC28877931	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850293	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3C(F)(F)F)Cc2cc1OC	InChI=1S/C28H26F3NO4/c1-33-23-9-8-18(15-32-11-10-17-12-25(34-2)26(35-3)13-19(17)16-32)21-14-24(36-27(21)23)20-6-4-5-7-22(20)28(29,30)31/h4-9,12-14H,10-11,15-16H2,1-3H3	RDAVKEYAUFGPDX-UHFFFAOYSA-N	50203563	6,7-dimethoxy-2-((7-methoxy-2-(2-(trifluoromethyl)phenyl)benzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL246852	Alpha-2C adrenergic receptor		 18								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203563&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11225732	104082644		CHEMBL246852				ZINC28877993	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850300	COc1cc2CCN(Cc3cnc(N)n4nc(nc34)-c3ccco3)Cc2cc1OC	InChI=1S/C21H22N6O3/c1-28-17-8-13-5-6-26(11-14(13)9-18(17)29-2)12-15-10-23-21(22)27-20(15)24-19(25-27)16-4-3-7-30-16/h3-4,7-10H,5-6,11-12H2,1-2H3,(H2,22,23)	HXHKXXRIQOWOHI-UHFFFAOYSA-N	50203560	8-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-f]pyrimidin-5-amine::CHEMBL246228	Alpha-2C adrenergic receptor		 19								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203560	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203560&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438147	104082641		CHEMBL246228				ZINC28877925	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850303	C1CN=C(N1)C1COc2ccccc2O1	InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	HPMRFMKYPGXPEP-UHFFFAOYSA-N	50019848	2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan	Alpha-2C adrenergic receptor		 19								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54459	103930771	5862	CHEMBL10316			C10968	ZINC00900630	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850304	COc1cccc(c1)-c1cc2c(CN3CCc4cc(OC)c(OC)cc4C3)ccc(OC)c2o1	InChI=1S/C28H29NO5/c1-30-22-7-5-6-19(12-22)25-15-23-20(8-9-24(31-2)28(23)34-25)16-29-11-10-18-13-26(32-3)27(33-4)14-21(18)17-29/h5-9,12-15H,10-11,16-17H2,1-4H3	HIASAPHKGILEIV-UHFFFAOYSA-N	50203565	6,7-dimethoxy-2-((7-methoxy-2-(3-methoxyphenyl)benzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL246639	Alpha-2C adrenergic receptor		 19								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203565&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438152	104082646		CHEMBL246639				ZINC28877959	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850308	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)N3CCC(CC3)N3CCCC3)Cc2cc1OC	InChI=1S/C31H39N3O5/c1-36-26-7-6-22(19-32-13-8-21-16-27(37-2)28(38-3)17-23(21)20-32)25-18-29(39-30(25)26)31(35)34-14-9-24(10-15-34)33-11-4-5-12-33/h6-7,16-18,24H,4-5,8-15,19-20H2,1-3H3	IVEMQVDPOPYVKY-UHFFFAOYSA-N	50203561	(4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-7-methoxybenzofuran-2-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone::CHEMBL247665	Alpha-2C adrenergic receptor		 3.5								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203561&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438168	104082642		CHEMBL247665				ZINC28878084	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850312	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccc3)Cc2cc1OC	InChI=1S/C27H27NO4/c1-29-23-10-9-20(22-15-24(32-27(22)23)18-7-5-4-6-8-18)16-28-12-11-19-13-25(30-2)26(31-3)14-21(19)17-28/h4-10,13-15H,11-12,16-17H2,1-3H3	LNYCQEZPPFYNOL-UHFFFAOYSA-N	50203555	6,7-dimethoxy-2-((7-methoxy-2-phenylbenzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL392992	Alpha-2C adrenergic receptor		 20								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203555&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16725934	104082636		CHEMBL392992				ZINC13983081	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850313	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NCCN(C)C)Cc2cc1OC	InChI=1S/C26H33N3O5/c1-28(2)11-9-27-26(30)24-14-20-18(6-7-21(31-3)25(20)34-24)15-29-10-8-17-12-22(32-4)23(33-5)13-19(17)16-29/h6-7,12-14H,8-11,15-16H2,1-5H3,(H,27,30)	IWHCCXKZMXALTR-UHFFFAOYSA-N	50203562	4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-N-(2-(dimethylamino)ethyl)-7-methoxybenzofuran-2-carboxamide::CHEMBL428407	Alpha-2C adrenergic receptor		 9.4								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203562&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438165	104082643		CHEMBL428407				ZINC28878060	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850314	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2C adrenergic receptor		 1.9								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850316	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)C(=O)NC3CN4CCC3CC4)Cc2cc1OC	InChI=1S/C29H35N3O5/c1-34-24-5-4-20(15-32-11-8-19-12-25(35-2)26(36-3)13-21(19)16-32)22-14-27(37-28(22)24)29(33)30-23-17-31-9-6-18(23)7-10-31/h4-5,12-14,18,23H,6-11,15-17H2,1-3H3,(H,30,33)	RKQFKAILJGXGRP-UHFFFAOYSA-N	50203558	4-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-7-methoxy-N-(quinuclidin-3-yl)benzofuran-2-carboxamide::CHEMBL394218	Alpha-2C adrenergic receptor		 0.800000								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203558&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438167	104082639		CHEMBL394218				ZINC28878079	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50850320	COc1cc2CCN(Cc3ccc(OC)c4oc(cc34)-c3ccccn3)Cc2cc1OC	InChI=1S/C26H26N2O4/c1-29-22-8-7-18(20-14-23(32-26(20)22)21-6-4-5-10-27-21)15-28-11-9-17-12-24(30-2)25(31-3)13-19(17)16-28/h4-8,10,12-14H,9,11,15-16H2,1-3H3	VLMCHIMKCURVRR-UHFFFAOYSA-N	50203556	6,7-dimethoxy-2-((7-methoxy-2-(pyridin-2-yl)benzofuran-4-yl)methyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL246229	Alpha-2C adrenergic receptor		 9.6								ChEMBL	10.1016/j.bmcl.2006.12.094	10.7270/Q2TD9Z5F	17257841			Hagihara, K; Kashima, H; Iida, K; Enokizono, J; Uchida, S; Nonaka, H; Kurokawa, M; Shimada, J	Kyowa Hakko Kogyo Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203556&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44438148	104082637		CHEMBL246229				ZINC28877933	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50840709	Oc1cc2OCC3NCc4ccccc4C3c2cc1O	InChI=1S/C16H15NO3/c18-13-5-11-15(6-14(13)19)20-8-12-16(11)10-4-2-1-3-9(10)7-17-12/h1-6,12,16-19H,7-8H2	QDUNOUQOKOYLCH-UHFFFAOYSA-N	50200351	(+/-)-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline::CHEMBL217299	Alpha-2C adrenergic receptor		 2								ChEMBL	10.1021/jm0604979	10.7270/Q25T3M92	17154515			Cueva, JP; Giorgioni, G; Grubbs, RA; Chemel, BR; Watts, VJ; Nichols, DE	Purdue University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200351&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25142456	104080715		CHEMBL217299				ZINC34801104	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50845574	COc1cc2NCC3C(CN4CCN(C\C(C)=C\c5ccccc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H34N4O3/c1-19(13-20-7-5-4-6-8-20)17-30-9-11-31(12-10-30)18-26-22-16-28-23-15-25(33-3)24(32-2)14-21(23)27(22)29-34-26/h4-8,13-15,22,26,28H,9-12,16-18H2,1-3H3/b19-13+	JODRRUQCPGURFJ-CPNJWEJPSA-N	50209684	CHEMBL390718::cis-(+)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3,3a,4,5-tetrahydroquinolino[4,3-c]isoxazole	Alpha-2C adrenergic receptor		 8.30								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209684&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44424854	104086408		CHEMBL390718				ZINC28654956	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50845590	COc1cc2OC[C@H]3[C@H](CN4CCN(C\C(C)=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C27H32FN3O4/c1-18(12-19-4-6-20(28)7-5-19)15-30-8-10-31(11-9-30)16-26-22-17-34-23-14-25(33-3)24(32-2)13-21(23)27(22)29-35-26/h4-7,12-14,22,26H,8-11,15-17H2,1-3H3/b18-12+/t22-,26-/m0/s1	UCNOTTVNPRSTFW-XSFNXXSESA-N	50146518	(3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]-piperazin-1-ylmethyl}-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL318235::R-226161::cis-(+)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole	Alpha-2C adrenergic receptor		 10.00								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146518&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16655023	104035107		CHEMBL318235				ZINC26742166	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50845591	COc1cc2OCC3C(CN4CCN(C\C=C\c5ccc(F)cc5)CC4)ON=C3c2cc1OC	InChI=1S/C26H30FN3O4/c1-31-23-14-20-22(15-24(23)32-2)33-17-21-25(34-28-26(20)21)16-30-12-10-29(11-13-30)9-3-4-18-5-7-19(27)8-6-18/h3-8,14-15,21,25H,9-13,16-17H2,1-2H3/b4-3+	CVKQUGPVDVFRAT-ONEGZZNKSA-N	50209685	CHEMBL226636::cis-(+)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(+/-)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole::cis-(-)-7,8-dimethoxy-3-[4-(3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole	Alpha-2C adrenergic receptor		 72								ChEMBL	10.1016/j.bmc.2007.03.053	10.7270/Q2BZ66VB	17407815			Andres, JI; Alcazar, J; Alonso, JM; Alvarez, RM; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernandez, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martinez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209685&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44424855	104086409		CHEMBL226636				ZINC28654969	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50907237	COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23	InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	WSVWKHTVFGTTKJ-AWEZNQCLSA-N	50160160	(S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-9,11-dioxa-6-aza-benzo[fg]cyclopenta[b]anthracene::CHEMBL179440	Alpha-2C adrenergic receptor		 181								ChEMBL	10.1016/j.bmcl.2009.11.053	10.7270/Q2C53MT3	19963380			Legendre, O; Pecic, S; Chaudhary, S; Zimmerman, SM; Fantegrossi, WE; Harding, WW	Hunter College and the Graduate Center of the City University of New York	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160160	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160160&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			197001	104046720	68992	CHEMBL179440				ZINC00338136	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50912762	OC[C@H]1O[C@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O	InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-25,27-30H,6H2/t13-,15-,17+,18-,21-/m1/s1	DPFYPHSPTUZJJT-DHALZPNHSA-N	50318294	CHEMBL1098724::miquelianin	Alpha-2C adrenergic receptor		 4063								ChEMBL	10.1021/np1000329	10.7270/Q2H99642	20408551			Nahrstedt, A; Butterweck, V	Westfalische Wilhelms-Universitat	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50318294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50318294&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12304323	104152655		CHEMBL1098724			C01140	ZINC21992895	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50912763	C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(O)c4c(cc(O)cc4=O)oc3-c3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O	InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-30,32-38H,7H2,1H3/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-/m0/s1	HRFGZDXDXWODFE-NVPNHPEKSA-N	50217942	2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside::3-Rhamnoglucosylquercetin::3-Rutinosyl quercetin::CHEMBL226335::cid_5280805::rutin	Alpha-2C adrenergic receptor		 9637								ChEMBL	10.1021/np1000329	10.7270/Q2H99642	20408551			Nahrstedt, A; Butterweck, V	Westfalische Wilhelms-Universitat	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217942	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217942&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	RUT	1RY8	5280805	104091802	28527	CHEMBL226335			C02757	ZINC04096846	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50921316	Fc1nc(cs1)C#Cc1cc(F)cc(c1)C#N	InChI=1S/C12H4F2N2S/c13-10-4-8(3-9(5-10)6-15)1-2-11-7-17-12(14)16-11/h3-5,7H	LVXAMCKZCLWWTF-UHFFFAOYSA-N	50336843	3-((2-Fluorothiazol-4-yl)ethynyl)-5-fluorobenzonitrile::CHEMBL1672288	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1021/jm101430m	10.7270/Q26Q1Z7T	21207959			Simeon, FG; Wendahl, MT; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336843&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			51050257	125086945		CHEMBL1672288				ZINC66078097	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50933846	C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)C(=O)c1ccc(F)cc1	InChI=1S/C22H22FNO2/c1-15-3-2-11-24(15)12-10-20-14-18-13-17(6-9-21(18)26-20)22(25)16-4-7-19(23)8-5-16/h4-9,13-15H,2-3,10-12H2,1H3/t15-/m1/s1	VGSYEFOBFMUWGO-OAHLLOKOSA-N	50158610	(4-Fluoro-phenyl)-{2-[2-((R)-2-methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-methanone::CHEMBL555146	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1021/jm201690h	10.7270/Q2BR8T6Z	22313227			Bao, X; Lu, S; Liow, JS; Zoghbi, SS; Jenko, KJ; Clark, DT; Gladding, RL; Innis, RB; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158610	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158610&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9906447	104045289		CHEMBL555146				ZINC03818810	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50933847	C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)C(=O)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C22H22N2O4/c1-15-3-2-11-23(15)12-10-20-14-18-13-17(6-9-21(18)28-20)22(25)16-4-7-19(8-5-16)24(26)27/h4-9,13-15H,2-3,10-12H2,1H3/t15-/m1/s1	GPZMWOXSIRVXQW-OAHLLOKOSA-N	50383117	CHEMBL2031737	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1021/jm201690h	10.7270/Q2BR8T6Z	22313227			Bao, X; Lu, S; Liow, JS; Zoghbi, SS; Jenko, KJ; Clark, DT; Gladding, RL; Innis, RB; Pike, VW	National Institute of Mental Health	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383117&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			56963799	160862200		CHEMBL2031737				ZINC84759385	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50936219	C(C1CCCCC1)N1CCCC1	InChI=1S/C11H21N/c1-2-6-11(7-3-1)10-12-8-4-5-9-12/h11H,1-10H2	ADGIWWYGVBZYMC-UHFFFAOYSA-N	50384293	CHEMBL2030634	Alpha-2C adrenergic receptor		 862								ChEMBL	10.1016/j.bmcl.2012.04.077	10.7270/Q2CF9R4T	22607684			Banister, SD; Rendina, LM; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384293&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			199798	160863376		CHEMBL2030634				ZINC03641799	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50936222	C(N1C2CCC1CC2)C12C3C4C5C3C1C5C24	InChI=1S/C15H19N/c1-2-7-4-3-6(1)16(7)5-15-12-9-8-10(12)14(15)11(8)13(9)15/h6-14H,1-5H2	TWUZJTIHFYRNSV-UHFFFAOYSA-N	50384286	CHEMBL2030626	Alpha-2C adrenergic receptor		 4264								ChEMBL	10.1016/j.bmcl.2012.04.077	10.7270/Q2CF9R4T	22607684			Banister, SD; Rendina, LM; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384286&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			66561967	160863369		CHEMBL2030626				ZINC84669079	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50934785	C[C@@H]1[C@H]2CN(CCC3(CCCCC3)C(O)=O)CC[C@@H]2Cc2[nH]c3ccc(cc3c12)C(F)(F)F	InChI=1S/C26H33F3N2O2/c1-16-20-15-31(12-10-25(24(32)33)8-3-2-4-9-25)11-7-17(20)13-22-23(16)19-14-18(26(27,28)29)5-6-21(19)30-22/h5-6,14,16-17,20,30H,2-4,7-13,15H2,1H3,(H,32,33)/t16-,17-,20-/m1/s1	WAOZNBXSEVIAGX-MBOZVWFJSA-N	50383522	CHEMBL2032049	Alpha-2C adrenergic receptor		>2000								ChEMBL	10.1016/j.bmcl.2012.04.006	10.7270/Q2542PMN	22542010			Mihalic, JT; Fan, P; Chen, X; Chen, X; Fu, Y; Motani, A; Liang, L; Lindstrom, M; Tang, L; Chen, JL; Jaen, J; Dai, K; Li, L	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383522	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383522&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10004545	160862605		CHEMBL2032049				ZINC34074273	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50945460	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2C adrenergic receptor		 9.3								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50945461	CC1CNC(N1)=Nc1c(Cl)cccc1Cl	InChI=1S/C10H11Cl2N3/c1-6-5-13-10(14-6)15-9-7(11)3-2-4-8(9)12/h2-4,6H,5H2,1H3,(H2,13,14,15)	ITKQNORKNISIMB-UHFFFAOYSA-N	50387823	CHEMBL2058631	Alpha-2C adrenergic receptor		 5754								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387823&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			12699315	160866906		CHEMBL2058631				ZINC28240471	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50945462	C1CC1C(NC1=[NH+]CCO1)C1CC1	InChI=1S/C10H16N2O/c1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10/h7-9H,1-6H2,(H,11,12)/p+1	CQXADFVORZEARL-UHFFFAOYSA-O	50262235	rilmenidine	Alpha-2C adrenergic receptor		 13								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262235&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44577959	104110975					C11120	ZINC00009708	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50945469	CC1CCC(N1)=Nc1ccc(I)cc1Cl	InChI=1S/C11H12ClIN2/c1-7-2-5-11(14-7)15-10-4-3-8(13)6-9(10)12/h3-4,6-7H,2,5H2,1H3,(H,14,15)	KLIBTBNNCGHLPY-UHFFFAOYSA-N	50387827	CHEMBL2058635	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387827&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10042547	160866910		CHEMBL2058635				ZINC67980450	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50945470	Clc1ccccc1N=C1CCCN1	InChI=1S/C10H11ClN2/c11-8-4-1-2-5-9(8)13-10-6-3-7-12-10/h1-2,4-5H,3,6-7H2,(H,12,13)	DADXHMUZIXRGOH-UHFFFAOYSA-N	50387825	CHEMBL2058633	Alpha-2C adrenergic receptor		 5012								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387825&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			7059292	160866908		CHEMBL2058633				ZINC03866613	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50945471	CC1CCC(N1)=Nc1ccccc1Cl	InChI=1S/C11H13ClN2/c1-8-6-7-11(13-8)14-10-5-3-2-4-9(10)12/h2-5,8H,6-7H2,1H3,(H,13,14)	HPOVQRXZQJTUKW-UHFFFAOYSA-N	50387826	CHEMBL2058634	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387826&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70686398	160866909		CHEMBL2058634				ZINC84707280	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50945477	CC1COC(N1)=NC(C1CC1)C1CC1	InChI=1S/C11H18N2O/c1-7-6-14-11(12-7)13-10(8-2-3-8)9-4-5-9/h7-10H,2-6H2,1H3,(H,12,13)	PNHRXBTZWMJDSC-UHFFFAOYSA-N	50387824	CHEMBL2058632	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.06.008	10.7270/Q26Q1Z9Q	22750139			Schann, S; Greney, H; Gasparik, V; Dontenwill, M; Rascente, C; Lacroix, G; Monassier, L; Bruban, V; Feldman, J; Ehrhardt, JD; Bousquet, P	University of Strasburg	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387824&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70696790	160866907		CHEMBL2058632				ZINC84671926	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984730	C1CN=C(N1)C1COc2ccccc2O1	InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	HPMRFMKYPGXPEP-UHFFFAOYSA-N	50019848	2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan	Alpha-2C adrenergic receptor			 54							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54459	103930771	5862	CHEMBL10316			C10968	ZINC00900630	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984740	Cc1nc2ccccn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H21N3O2/c1-15-16(22(26)25-11-5-4-8-21(25)23-15)9-12-24-13-10-20-18(14-24)17-6-2-3-7-19(17)27-20/h2-8,11H,9-10,12-14H2,1H3	ZYXHQIPQIKTEDI-UHFFFAOYSA-N	50403744	LUSAPERIDONE	Alpha-2C adrenergic receptor			 1.7							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403744	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403744&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3045401	163352768						ZINC01903948	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984753	O=c1c(CCN2CCc3oc4ccccc4c3C2)c(Cc2ccccc2)nc2ccccn12	InChI=1S/C28H25N3O2/c32-28-22(13-16-30-17-14-26-23(19-30)21-10-4-5-11-25(21)33-26)24(18-20-8-2-1-3-9-20)29-27-12-6-7-15-31(27)28/h1-12,15H,13-14,16-19H2	WGLYZLZIIJTKAG-UHFFFAOYSA-N	50403751	CHEMBL162436	Alpha-2C adrenergic receptor			 2.7							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403751	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403751&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376975	163352775		CHEMBL162436				ZINC27856272	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984759	Cc1nc2ccc(I)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H20IN3O2/c1-14-16(22(27)26-12-15(23)6-7-21(26)24-14)8-10-25-11-9-20-18(13-25)17-4-2-3-5-19(17)28-20/h2-7,12H,8-11,13H2,1H3	RTXNZOCMRSFEID-UHFFFAOYSA-N	50403753	CHEMBL162682	Alpha-2C adrenergic receptor			 0.616595							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403753	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403753&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376984	163352777		CHEMBL162682				ZINC27850209	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984762	Cc1nc2ccccn2c(=O)c1CCN1CCc2oc3ccc(Cl)cc3c2C1	InChI=1S/C22H20ClN3O2/c1-14-16(22(27)26-9-3-2-4-21(26)24-14)7-10-25-11-8-20-18(13-25)17-12-15(23)5-6-19(17)28-20/h2-6,9,12H,7-8,10-11,13H2,1H3	RJGDAIXCXQIWEK-UHFFFAOYSA-N	50403741	CHEMBL165677	Alpha-2C adrenergic receptor			 28							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403741	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403741&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44377006	163352765		CHEMBL165677				ZINC27861658	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984764	Cc1nc2ccccn2c(=O)c1CCN1CCc2sc3ccccc3c2C1	InChI=1S/C22H21N3OS/c1-15-16(22(26)25-11-5-4-8-21(25)23-15)9-12-24-13-10-20-18(14-24)17-6-2-3-7-19(17)27-20/h2-8,11H,9-10,12-14H2,1H3	JMXRRARDLWHYJN-UHFFFAOYSA-N	50403749	CHEMBL165181	Alpha-2C adrenergic receptor			 14							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403749	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403749&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9951544	163352773		CHEMBL165181				ZINC00588307	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984765	Cc1nc2c(O)cccn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H21N3O3/c1-14-15(22(27)25-10-4-6-18(26)21(25)23-14)8-11-24-12-9-20-17(13-24)16-5-2-3-7-19(16)28-20/h2-7,10,26H,8-9,11-13H2,1H3	UDURNHDRCUMUOV-UHFFFAOYSA-N	50403747	CHEMBL162826	Alpha-2C adrenergic receptor			 1.6							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403747	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403747&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376900	163352771		CHEMBL162826				ZINC27848632	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984766	Cc1nc2ccc(Br)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H20BrN3O2/c1-14-16(22(27)26-12-15(23)6-7-21(26)24-14)8-10-25-11-9-20-18(13-25)17-4-2-3-5-19(17)28-20/h2-7,12H,8-11,13H2,1H3	BRKWIMBSEICBCU-UHFFFAOYSA-N	50403740	CHEMBL165350	Alpha-2C adrenergic receptor			 0.691831							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403740	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403740&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44377200	163352764		CHEMBL165350				ZINC27859028	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984769	Cc1cc(C)n2c(c1)nc(C)c(CCN1CCc3oc4ccccc4c3C1)c2=O	InChI=1S/C24H25N3O2/c1-15-12-16(2)27-23(13-15)25-17(3)18(24(27)28)8-10-26-11-9-22-20(14-26)19-6-4-5-7-21(19)29-22/h4-7,12-13H,8-11,14H2,1-3H3	GICQFAWDMCTLDM-UHFFFAOYSA-N	50403748	CHEMBL162232	Alpha-2C adrenergic receptor			 0.851138							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403748	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403748&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376954	163352772		CHEMBL162232				ZINC27858298	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984782	Cc1nc2c(Cl)cc(Cl)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H19Cl2N3O2/c1-13-15(22(28)27-11-14(23)10-18(24)21(27)25-13)6-8-26-9-7-20-17(12-26)16-4-2-3-5-19(16)29-20/h2-5,10-11H,6-9,12H2,1H3	AKZOIEBLVQLVTR-UHFFFAOYSA-N	50403739	CHEMBL163247	Alpha-2C adrenergic receptor			 1.3							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403739&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376993	163352763		CHEMBL163247				ZINC27856891	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984783	Cc1nc2ccccn2c(=O)c1CCN1CCc2oc3c(Cl)cccc3c2C1	InChI=1S/C22H20ClN3O2/c1-14-15(22(27)26-10-3-2-7-20(26)24-14)8-11-25-12-9-19-17(13-25)16-5-4-6-18(23)21(16)28-19/h2-7,10H,8-9,11-13H2,1H3	HNRZWHPQDGUUSO-UHFFFAOYSA-N	50403754	CHEMBL164612	Alpha-2C adrenergic receptor			 2.2							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403754&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44377007	163352778		CHEMBL164612				ZINC27862211	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984789	Cc1nc2ccc(Cl)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C22H20ClN3O2/c1-14-16(22(27)26-12-15(23)6-7-21(26)24-14)8-10-25-11-9-20-18(13-25)17-4-2-3-5-19(17)28-20/h2-7,12H,8-11,13H2,1H3	GZFYZEHGCPEJAC-UHFFFAOYSA-N	50403738	CHEMBL351483	Alpha-2C adrenergic receptor			 0.724436							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403738&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44377036	163352762		CHEMBL351483				ZINC27865233	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984792	Cc1nc2c(Cl)cc(cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1)C(F)(F)F	InChI=1S/C23H19ClF3N3O2/c1-13-15(22(31)30-11-14(23(25,26)27)10-18(24)21(30)28-13)6-8-29-9-7-20-17(12-29)16-4-2-3-5-19(16)32-20/h2-5,10-11H,6-9,12H2,1H3	JRMVEEDZCPVFFK-UHFFFAOYSA-N	50403746	CHEMBL162147	Alpha-2C adrenergic receptor			 3.6							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403746	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403746&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376927	163352770		CHEMBL162147				ZINC27855969	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984793	CN1CCN2C(C1)c1ccccc1Cc1cccnc21	InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3	RONZAEMNMFQXRA-UHFFFAOYSA-N	50115644	(+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::2-methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::CHEMBL654::MIRTAZAPINE::ORG 3770::REMERON	Alpha-2C adrenergic receptor			 200							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115644&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4205	104009532	6950	CHEMBL654	DB00370	7241	C07570	ZINC19702119	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984794	Cc1ccc2nc(C)c(CCN3CCc4oc5ccccc5c4C3)c(=O)n2c1	InChI=1S/C23H23N3O2/c1-15-7-8-22-24-16(2)17(23(27)26(22)13-15)9-11-25-12-10-21-19(14-25)18-5-3-4-6-20(18)28-21/h3-8,13H,9-12,14H2,1-2H3	FPQNWBCHCMEAKI-UHFFFAOYSA-N	50403752	CHEMBL162370	Alpha-2C adrenergic receptor			 1.3							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403752	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403752&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			22120322	163352776		CHEMBL162370				ZINC01903957	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984800	COc1cccn2c1nc(C)c(CCN1CCc3oc4ccccc4c3C1)c2=O	InChI=1S/C23H23N3O3/c1-15-16(23(27)26-11-5-8-21(28-2)22(26)24-15)9-12-25-13-10-20-18(14-25)17-6-3-4-7-19(17)29-20/h3-8,11H,9-10,12-14H2,1-2H3	HPNSJGWCFMHOJX-UHFFFAOYSA-N	50403745	CHEMBL162490	Alpha-2C adrenergic receptor			 0.707946							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403745&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			22120332	163352769		CHEMBL162490				ZINC27849549	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984801	Cc1ccn2c(c1)nc(C)c(CCN1CCc3oc4ccccc4c3C1)c2=O	InChI=1S/C23H23N3O2/c1-15-7-12-26-22(13-15)24-16(2)17(23(26)27)8-10-25-11-9-21-19(14-25)18-5-3-4-6-20(18)28-21/h3-7,12-13H,8-11,14H2,1-2H3	FGTWZUQEDNXLLZ-UHFFFAOYSA-N	50403742	CHEMBL165796	Alpha-2C adrenergic receptor			 1.2							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403742&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376958	163352766		CHEMBL165796				ZINC27862731	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984805	Cc1nc2ccccn2c(=O)c1CCCN1CCc2oc3ccccc3c2C1	InChI=1S/C23H23N3O2/c1-16-17(23(27)26-13-5-4-10-22(26)24-16)8-6-12-25-14-11-21-19(15-25)18-7-2-3-9-20(18)28-21/h2-5,7,9-10,13H,6,8,11-12,14-15H2,1H3	KKLYBLFGKSXYJZ-UHFFFAOYSA-N	50403737	CHEMBL165776	Alpha-2C adrenergic receptor			 6.6							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403737&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376936	163352761		CHEMBL165776				ZINC27869119	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984808	Cc1nc2c(C)cccn2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C23H23N3O2/c1-15-6-5-11-26-22(15)24-16(2)17(23(26)27)9-12-25-13-10-21-19(14-25)18-7-3-4-8-20(18)28-21/h3-8,11H,9-10,12-14H2,1-2H3	WLWNODXEXGTHDO-UHFFFAOYSA-N	50403750	CHEMBL351200	Alpha-2C adrenergic receptor			 1.3							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403750&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44377035	163352774		CHEMBL351200				ZINC27864607	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984809	COc1cc2nc(C)c(CCN3CCc4oc5ccccc5c4C3)c(=O)n2cc1OC	InChI=1S/C24H25N3O4/c1-15-16(24(28)27-14-22(30-3)21(29-2)12-23(27)25-15)8-10-26-11-9-20-18(13-26)17-6-4-5-7-19(17)31-20/h4-7,12,14H,8-11,13H2,1-3H3	MBPZQLMDDBIIGZ-UHFFFAOYSA-N	50403743	CHEMBL162058	Alpha-2C adrenergic receptor			 58							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403743	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403743&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376845	163352767		CHEMBL162058				ZINC27854972	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50984811	Cc1nc2cccc(C)n2c(=O)c1CCN1CCc2oc3ccccc3c2C1	InChI=1S/C23H23N3O2/c1-15-6-5-9-22-24-16(2)17(23(27)26(15)22)10-12-25-13-11-21-19(14-25)18-7-3-4-8-20(18)28-21/h3-9H,10-14H2,1-2H3	PUJAGVRPJZNJPF-UHFFFAOYSA-N	50403755	CHEMBL163190	Alpha-2C adrenergic receptor			 1.1							ChEMBL	10.1016/s0960-894x(99)00591-0	10.7270/Q2T72JMX	10636247			Kennis, LE; Bischoff, FP; Mertens, CJ; Love, CJ; Van den Keybus, FA; Pieters, S; Braeken, M; Megens, AA; Leysen, JE	Janssen Research Foundation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403755	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403755&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44376923	163352779		CHEMBL163190				ZINC27855924	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979964	COc1cc2oc(C(=O)N(CCCN3CCCCC3)c3ccccc3)c(C)c2cc1OC	InChI=1S/C26H32N2O4/c1-19-21-17-23(30-2)24(31-3)18-22(21)32-25(19)26(29)28(20-11-6-4-7-12-20)16-10-15-27-13-8-5-9-14-27/h4,6-7,11-12,17-18H,5,8-10,13-16H2,1-3H3	RQJPWNOKFLOHKI-UHFFFAOYSA-N	50401674	CHEMBL2205362	Alpha-2C adrenergic receptor		 1542								ChEMBL	10.1016/j.bmc.2012.09.044	10.7270/Q2833T6W	23084435			Marriott, KS; Morrison, AZ; Moore, M; Olubajo, O; Stewart, LE	Savannah State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401674&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71463022	163350698		CHEMBL2205362				ZINC95563125	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979969	Cc1c(oc2ccccc12)C(=O)N(CCCN1CCCCC1)c1ccccc1	InChI=1S/C24H28N2O2/c1-19-21-13-6-7-14-22(21)28-23(19)24(27)26(20-11-4-2-5-12-20)18-10-17-25-15-8-3-9-16-25/h2,4-7,11-14H,3,8-10,15-18H2,1H3	CTMDNCSJPPQMLF-UHFFFAOYSA-N	50401675	CHEMBL2205361	Alpha-2C adrenergic receptor		 249								ChEMBL	10.1016/j.bmc.2012.09.044	10.7270/Q2833T6W	23084435			Marriott, KS; Morrison, AZ; Moore, M; Olubajo, O; Stewart, LE	Savannah State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401675&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71452341	163350699		CHEMBL2205361				ZINC95558674	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979028	OC12C3C4C5C3C(C3C5CC4C13)N2CCc1ccccn1	InChI=1S/C18H20N2O/c21-18-15-10-7-9-11-12(10)16(18)14(11)17(13(9)15)20(18)6-4-8-3-1-2-5-19-8/h1-3,5,9-17,21H,4,6-7H2	ABONQAUMSMWLEK-UHFFFAOYSA-N	50401359	CHEMBL2205816	Alpha-2C adrenergic receptor		 1835								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401359&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71452384	163350383		CHEMBL2205816					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979036	OC12C3C4C5C3C(C3C5CC4C13)N2Cc1ccccc1	InChI=1S/C18H19NO/c20-18-15-10-6-9-11-12(10)16(18)14(11)17(13(9)15)19(18)7-8-4-2-1-3-5-8/h1-5,9-17,20H,6-7H2	YSEXVIPNIGQQMN-UHFFFAOYSA-N	50288954	11-benzyl-11-azahexacyclo[5.4.1.02,6.03,10.04,8.09,12]dodecan-1-ol; hydrochloride::CHEMBL1189234::CHEMBL538300	Alpha-2C adrenergic receptor		 682								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288954	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288954&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			36381	104130525		CHEMBL538300CHEMBL1189234					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979053	COc1ccc(CN2C3C4C5C6C4C2(O)C2C6CC5C32)cc1OC	InChI=1S/C20H23NO3/c1-23-11-4-3-8(5-12(11)24-2)7-21-19-15-9-6-10-14-13(9)16(19)18(14)20(21,22)17(10)15/h3-5,9-10,13-19,22H,6-7H2,1-2H3	MGYAQEPRQTVZOM-UHFFFAOYSA-N	50401363	CHEMBL2205827	Alpha-2C adrenergic receptor		 1145								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401363&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71455894	163350387		CHEMBL2205827					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979071	OC12C3C4C5C3C(C3C5CC4C13)N2Cc1ccc2OCOc2c1	InChI=1S/C19H19NO3/c21-19-16-9-4-8-12-13(9)17(19)15(12)18(14(8)16)20(19)5-7-1-2-10-11(3-7)23-6-22-10/h1-3,8-9,12-18,21H,4-6H2	AVNYJOIRGGOFFW-UHFFFAOYSA-N	50401367	CHEMBL2205829	Alpha-2C adrenergic receptor		 1783								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401367	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401367&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71452387	163350391		CHEMBL2205829					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979106	COc1ccc(CCN2C3C4C5C6C4C2(O)C2C6CC5C32)cc1OC	InChI=1S/C21H25NO3/c1-24-12-4-3-9(7-13(12)25-2)5-6-22-20-16-10-8-11-15-14(10)17(20)19(15)21(22,23)18(11)16/h3-4,7,10-11,14-20,23H,5-6,8H2,1-2H3	KULMFBVVFDTVNX-UHFFFAOYSA-N	50401375	CHEMBL2205814	Alpha-2C adrenergic receptor		 1874								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401375&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71452383	163350399		CHEMBL2205814					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979117	COc1cccc(CCN2C3C4C5C6C4C2(O)C2C6CC5C32)c1OC	InChI=1S/C21H25NO3/c1-24-12-5-3-4-9(20(12)25-2)6-7-22-19-15-10-8-11-14-13(10)16(19)18(14)21(22,23)17(11)15/h3-5,10-11,13-19,23H,6-8H2,1-2H3	FOTUXOOYRRRHFQ-UHFFFAOYSA-N	50401368	CHEMBL2205813	Alpha-2C adrenergic receptor		 4347								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401368	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401368&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71463061	163350392		CHEMBL2205813					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979129	COc1ccc(CCN2C3C4C5C6C4C2(O)C2C6CC5C32)cc1	InChI=1S/C20H23NO2/c1-23-10-4-2-9(3-5-10)6-7-21-19-15-11-8-12-14-13(11)16(19)18(14)20(21,22)17(12)15/h2-5,11-19,22H,6-8H2,1H3	TWMXGXSGGIIQDM-UHFFFAOYSA-N	50401376	CHEMBL2205812	Alpha-2C adrenergic receptor		 1704								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401376&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71452382	163350400		CHEMBL2205812					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979146	COc1cccc(CCN2C3C4C5C6C4C2(O)C2C6CC5C32)c1	InChI=1S/C20H23NO2/c1-23-10-4-2-3-9(7-10)5-6-21-19-15-11-8-12-14-13(11)16(19)18(14)20(21,22)17(12)15/h2-4,7,11-19,22H,5-6,8H2,1H3	ZKOQRCXMSDAJIR-UHFFFAOYSA-N	50401361	CHEMBL2205811	Alpha-2C adrenergic receptor		 557								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401361&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71459604	163350385		CHEMBL2205811					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979163	COc1ccccc1CCN1C2C3C4C5C3C1(O)C1C5CC4C21	InChI=1S/C20H23NO2/c1-23-12-5-3-2-4-9(12)6-7-21-19-15-10-8-11-14-13(10)16(19)18(14)20(21,22)17(11)15/h2-5,10-11,13-19,22H,6-8H2,1H3	PSBBAGWMKGXQRW-UHFFFAOYSA-N	50401362	CHEMBL2205836	Alpha-2C adrenergic receptor		 533								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401362&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71450550	163350386		CHEMBL2205836					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979174	COc1ccc(CN2C3C4C5C6C4C2(O)C2C6CC5C32)cc1	InChI=1S/C19H21NO2/c1-22-9-4-2-8(3-5-9)7-20-18-14-10-6-11-13-12(10)15(18)17(13)19(20,21)16(11)14/h2-5,10-18,21H,6-7H2,1H3	GYKFQDQFKGGVKD-UHFFFAOYSA-N	50401382	CHEMBL2205825	Alpha-2C adrenergic receptor		 1491								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401382&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71463063	163350406		CHEMBL2205825					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979177	COc1cccc(CN2C3C4C5C6C4C2(O)C2C6CC5C32)c1	InChI=1S/C19H21NO2/c1-22-9-4-2-3-8(5-9)7-20-18-14-10-6-11-13-12(10)15(18)17(13)19(20,21)16(11)14/h2-5,10-18,21H,6-7H2,1H3	LIKZWSUAMNZHAE-UHFFFAOYSA-N	50401383	CHEMBL2205824	Alpha-2C adrenergic receptor		 1369								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401383&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71450548	163350407		CHEMBL2205824					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50979187	COc1ccccc1CN1C2C3C4C5C3C1(O)C1C5CC4C21	InChI=1S/C19H21NO2/c1-22-11-5-3-2-4-8(11)7-20-18-14-9-6-10-13-12(9)15(18)17(13)19(20,21)16(10)14/h2-5,9-10,12-18,21H,6-7H2,1H3	WWXCWTRLUXMAHX-UHFFFAOYSA-N	50401384	CHEMBL2205823	Alpha-2C adrenergic receptor		 699								ChEMBL	10.1016/j.bmcl.2012.08.046	10.7270/Q2KH0PGM	22959245			Banister, SD; Manoli, M; Doddareddy, MR; Hibbs, DE; Kassiou, M	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401384&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			71457691	163350408		CHEMBL2205823					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50985696	CNCC1CC2N(O1)c1ccccc1Cc1ccccc21	InChI=1S/C18H20N2O/c1-19-12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)20(18)21-15/h2-9,15,18-19H,10-12H2,1H3	LCKBEOTXTNWYRG-UHFFFAOYSA-N	50403962	CHEMBL81485	Alpha-2C adrenergic receptor			<1000							ChEMBL	10.1016/s0960-894x(01)00721-1	10.7270/Q23J3F4C	11755364			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403962	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403962&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			19426635	163352986		CHEMBL81485				ZINC13436895	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50985700	CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21	InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3	SWGWJQBPCJEQJC-UHFFFAOYSA-N	50403957	CHEMBL313189	Alpha-2C adrenergic receptor			<1000							ChEMBL	10.1016/s0960-894x(01)00721-1	10.7270/Q23J3F4C	11755364			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403957&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44461606	163352981		CHEMBL313189				ZINC13436833	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50985761	CN(C)C[C@@H]1C[C@H]2N(O1)c1ccccc1Cc1ccccc21	InChI=1S/C19H22N2O/c1-20(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)21(19)22-16/h3-10,16,19H,11-13H2,1-2H3/t16-,19+/m0/s1	BTSCZNWXJQSJIE-QFBILLFUSA-N	50146360	CHEMBL328573::Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-yl)methyl]-amine	Alpha-2C adrenergic receptor			 1862							ChEMBL	10.1016/s0960-894x(01)00721-1	10.7270/Q23J3F4C	11755364			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146360&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9839081	104034979		CHEMBL328573				ZINC13436820	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50985765	CN(C)C[C@@H]1C[C@H]2N(O1)c1ccccc1Cc1ccccc21	InChI=1S/C19H22N2O/c1-20(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)21(19)22-16/h3-10,16,19H,11-13H2,1-2H3/t16-,19+/m0/s1	BTSCZNWXJQSJIE-QFBILLFUSA-N	50146360	CHEMBL328573::Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-yl)methyl]-amine	Alpha-2C adrenergic receptor			 1862							ChEMBL	10.1016/S0960-894X(01)00722-3	10.7270/Q2ZW1N3V	11755365			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146360&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9839081	104034979		CHEMBL328573				ZINC13436820	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50985775	CN(C)CC1CC2N(O1)c1cc(F)ccc1Cc1ccc(F)cc21	InChI=1S/C19H20F2N2O/c1-22(2)11-16-10-19-17-8-14(20)5-3-12(17)7-13-4-6-15(21)9-18(13)23(19)24-16/h3-6,8-9,16,19H,7,10-11H2,1-2H3	GEDGEGJCGBTAON-UHFFFAOYSA-N	50403976	CHEMBL314107	Alpha-2C adrenergic receptor			<1000							ChEMBL	10.1016/S0960-894X(01)00722-3	10.7270/Q2ZW1N3V	11755365			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403976	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403976&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10246054	163353000		CHEMBL314107				ZINC13437214	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50985776	CN(C)CC1CC2N(O1)c1cc(Cl)ccc1Cc1ccccc21	InChI=1S/C19H21ClN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3	JTLCTTWVUAIQHD-UHFFFAOYSA-N	50403975	CHEMBL315772	Alpha-2C adrenergic receptor			 871							ChEMBL	10.1016/S0960-894X(01)00722-3	10.7270/Q2ZW1N3V	11755365			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403975&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10381889	163352999		CHEMBL315772				ZINC13437085	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50985785	CN(C)CC1CC2N(O1)c1cc(F)ccc1Cc1ccccc21	InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3	MSQRTETUBFIHMP-UHFFFAOYSA-N	50403974	CHEMBL84931	Alpha-2C adrenergic receptor			 1175							ChEMBL	10.1016/S0960-894X(01)00722-3	10.7270/Q2ZW1N3V	11755365			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403974	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403974&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44318454	163352998		CHEMBL84931				ZINC13437207	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50985741	Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21	InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H	YNPFMWCWRVTGKJ-UHFFFAOYSA-N	31005	2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine::MIANSERIN HYDROCHLORIDE::MLS000069681::SMR000058472::cid_68551	Alpha-2C adrenergic receptor			 43							ChEMBL	10.1016/s0960-894x(01)00721-1	10.7270/Q23J3F4C	11755364			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31005&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68551	242052839						ZINC00000504	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50985809	CN(C)CC1CC2N(O1)c1cc(C)ccc1Cc1ccccc21	InChI=1S/C20H24N2O/c1-14-8-9-16-11-15-6-4-5-7-18(15)20-12-17(13-21(2)3)23-22(20)19(16)10-14/h4-10,17,20H,11-13H2,1-3H3	IEMJYQZKJFERDW-UHFFFAOYSA-N	50403978	CHEMBL85735	Alpha-2C adrenergic receptor			<1000							ChEMBL	10.1016/S0960-894X(01)00722-3	10.7270/Q2ZW1N3V	11755365			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403978	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403978&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44318842	163353002		CHEMBL85735				ZINC13437098	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50985828	Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21	InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H	YNPFMWCWRVTGKJ-UHFFFAOYSA-N	31005	2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine::MIANSERIN HYDROCHLORIDE::MLS000069681::SMR000058472::cid_68551	Alpha-2C adrenergic receptor			 43							ChEMBL	10.1016/S0960-894X(01)00722-3	10.7270/Q2ZW1N3V	11755365			Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK	Janssen-Cilag S.A.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31005&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68551	242052839						ZINC00000504	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51013559	CC(OC1=NCCN1)c1ccccc1	InChI=1S/C11H14N2O/c1-9(10-5-3-2-4-6-10)14-11-12-7-8-13-11/h2-6,9H,7-8H2,1H3,(H,12,13)	MPCNSEQVVHOHGO-UHFFFAOYSA-N	50415135	CHEMBL571314	Alpha-2C adrenergic receptor		 263								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415135	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415135&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487144	163364159		CHEMBL571314				ZINC45255751	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51013561	CC(OC1=NCCN1)c1ccccc1C	InChI=1S/C12H16N2O/c1-9-5-3-4-6-11(9)10(2)15-12-13-7-8-14-12/h3-6,10H,7-8H2,1-2H3,(H,13,14)	NGYGSYPEYBVPQK-UHFFFAOYSA-N	50415137	CHEMBL570863	Alpha-2C adrenergic receptor		 269								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415137&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487089	163364161		CHEMBL570863				ZINC45254599	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51013562	CCCc1ccccc1C(C)OC1=NCCN1	InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)	CKZOGIXOGHVXNW-UHFFFAOYSA-N	50415138	CHEMBL576078	Alpha-2C adrenergic receptor		 148								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415138&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487955	163364162		CHEMBL576078				ZINC45301117	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51013563	CC(OC1=NCCN1)c1ccccc1C1CC1	InChI=1S/C14H18N2O/c1-10(17-14-15-8-9-16-14)12-4-2-3-5-13(12)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	BGPHEWUAKSHOBD-UHFFFAOYSA-N	50415139	CHEMBL576623	Alpha-2C adrenergic receptor		 79								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415139&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487956	163364163		CHEMBL576623				ZINC45290491	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51013565	Cc1ccccc1COC1=NCCN1	InChI=1S/C11H14N2O/c1-9-4-2-3-5-10(9)8-14-11-12-6-7-13-11/h2-5H,6-8H2,1H3,(H,12,13)	LGTDYALRCIBCMI-UHFFFAOYSA-N	50415141	CHEMBL576819	Alpha-2C adrenergic receptor		 501								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415141&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487958	163364165		CHEMBL576819				ZINC45299429	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51013566	CCCc1ccccc1COC1=NCCN1	InChI=1S/C13H18N2O/c1-2-5-11-6-3-4-7-12(11)10-16-13-14-8-9-15-13/h3-4,6-7H,2,5,8-10H2,1H3,(H,14,15)	XBWFPEVESQMIBM-UHFFFAOYSA-N	50415140	CHEMBL569933	Alpha-2C adrenergic receptor		 490								ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415140&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487962	163364164		CHEMBL569933				ZINC45255608	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51013575	CC(OC1=NCCN1)c1ccccc1CC=C	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MCAGSCISRRGDGQ-UHFFFAOYSA-N	50415136	CHEMBL570973	Alpha-2C adrenergic receptor					 50					ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415136&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45487145	163364160		CHEMBL570973				ZINC45257642	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51013578	C(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15)	YAORIDZYZDUZCM-UHFFFAOYSA-N	50027060	2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole::2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole (cirazoline)::CHEMBL13852::CIRAZOLINE	Alpha-2C adrenergic receptor					 398					ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027060&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2765	103936642		CHEMBL13852	DB09202	515		ZINC00001160	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51013581	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2C adrenergic receptor					 794					ChEMBL	10.1021/jm901262f	10.7270/Q2J104DZ	19886609			Cardinaletti, C; Mattioli, L; Ghelfi, F; Del Bello, F; Giannella, M; Bruzzone, A; Paris, H; Perfumi, M; Piergentili, A; Quaglia, W; Pigini, M	Universita degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006783	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2C adrenergic receptor					 794					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006793	COC1(COc2cccc(-c3ccccc3)c2O1)C1=NCCN1	InChI=1S/C18H18N2O3/c1-21-18(17-19-10-11-20-17)12-22-15-9-5-8-14(16(15)23-18)13-6-3-2-4-7-13/h2-9H,10-12H2,1H3,(H,19,20)	TVDZYHOTHAFPBR-UHFFFAOYSA-N	50412252	CHEMBL492648	Alpha-2C adrenergic receptor		 245								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412252&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906243	163361276		CHEMBL492648				ZINC45506014	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006795	C1CN=C(N1)C1COc2ccc(cc2O1)-c1ccccc1	InChI=1S/C17H16N2O2/c1-2-4-12(5-3-1)13-6-7-14-15(10-13)21-16(11-20-14)17-18-8-9-19-17/h1-7,10,16H,8-9,11H2,(H,18,19)	CENDKGWAICPCEX-UHFFFAOYSA-N	50412254	CHEMBL492445	Alpha-2C adrenergic receptor		 1259								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412254&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906203	163361278		CHEMBL492445				ZINC40949721	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006796	C1CN=C(N1)C1COc2cc(ccc2O1)-c1ccccc1	InChI=1S/C17H16N2O2/c1-2-4-12(5-3-1)13-6-7-14-15(10-13)20-11-16(21-14)17-18-8-9-19-17/h1-7,10,16H,8-9,11H2,(H,18,19)	MOEPMTDKDUFBNH-UHFFFAOYSA-N	50412255	CHEMBL492444	Alpha-2C adrenergic receptor		 1585								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412255&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906202	163361279		CHEMBL492444				ZINC40949717	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006799	CC(Oc1ccccc1C1CCCCC1)C1=NCCN1	InChI=1S/C17H24N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h5-6,9-10,13-14H,2-4,7-8,11-12H2,1H3,(H,18,19)	RIMQFOFQYZBTDB-UHFFFAOYSA-N	50412258	CHEMBL451229	Alpha-2C adrenergic receptor		 78								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412258&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			23622576	163361282		CHEMBL451229				ZINC40836200	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006800	CC(Oc1ccccc1C1CCCC1)C1=NCCN1	InChI=1S/C16H22N2O/c1-12(16-17-10-11-18-16)19-15-9-5-4-8-14(15)13-6-2-3-7-13/h4-5,8-9,12-13H,2-3,6-7,10-11H2,1H3,(H,17,18)	WIQCERUTOBWUOL-UHFFFAOYSA-N	50412244	CHEMBL495096	Alpha-2C adrenergic receptor		 27								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412244&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906199	163361268		CHEMBL495096				ZINC40430700	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006801	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2C adrenergic receptor		 85								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006802	CC(Oc1ccccc1\C=N\OCc1ccccc1)C1=NCCN1	InChI=1S/C19H21N3O2/c1-15(19-20-11-12-21-19)24-18-10-6-5-9-17(18)13-22-23-14-16-7-3-2-4-8-16/h2-10,13,15H,11-12,14H2,1H3,(H,20,21)/b22-13+	KUWSYGHOSHDWCB-LPYMAVHISA-N	50412246	CHEMBL495097	Alpha-2C adrenergic receptor		 676								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412246&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906197	163361270		CHEMBL495097				ZINC40957611	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006803	CCO\N=C\c1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H19N3O2/c1-3-18-17-10-12-6-4-5-7-13(12)19-11(2)14-15-8-9-16-14/h4-7,10-11H,3,8-9H2,1-2H3,(H,15,16)/b17-10+	BVWLLEDYRCHASI-LICLKQGHSA-N	50412247	CHEMBL492639	Alpha-2C adrenergic receptor		 339								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412247&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906196	163361271		CHEMBL492639				ZINC45506721	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006804	CO\N=C\c1ccccc1OC(C)C1=NCCN1	InChI=1S/C13H17N3O2/c1-10(13-14-7-8-15-13)18-12-6-4-3-5-11(12)9-16-17-2/h3-6,9-10H,7-8H2,1-2H3,(H,14,15)/b16-9+	YTQHOBJMFUQZEK-CXUHLZMHSA-N	50412248	CHEMBL442815	Alpha-2C adrenergic receptor		 3090								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412248&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906160	163361272		CHEMBL442815				ZINC40822924	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006805	CC(Oc1ccccc1CN=O)C1=NCCN1	InChI=1S/C12H15N3O2/c1-9(12-13-6-7-14-12)17-11-5-3-2-4-10(11)8-15-16/h2-5,9H,6-8H2,1H3,(H,13,14)	FZLNIHYBYXMHEO-UHFFFAOYSA-N	50412249	CHEMBL493675	Alpha-2C adrenergic receptor		 912								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412249&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91900410	163361273		CHEMBL493675				ZINC40430963	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006806	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2C adrenergic receptor		 200								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006807	COC1(COc2ccccc2O1)C1=NCCN1	InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)	HQGWKNGAKBPTBX-UHFFFAOYSA-N	50019492	(+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::(-)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-(2-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole::2-ethoxy-idazoxan::CHEMBL10332::RX-821002::RX821002	Alpha-2C adrenergic receptor		 0.794328								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019492&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			108094	103930440	73287	CHEMBL10332		528		ZINC03995905	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006808	C1CN=C(N1)C1COc2ccccc2O1	InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	HPMRFMKYPGXPEP-UHFFFAOYSA-N	50019848	2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan	Alpha-2C adrenergic receptor		 18								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54459	103930771	5862	CHEMBL10316			C10968	ZINC00900630	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006809	C1CN=C(N1)C(Oc1ccccc1)c1ccccc1	InChI=1S/C16H16N2O/c1-3-7-13(8-4-1)15(16-17-11-12-18-16)19-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H,17,18)	OABROWXKGQFLDH-UHFFFAOYSA-N	50412251	CHEMBL494885	Alpha-2C adrenergic receptor		 65								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412251&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44568614	163361275		CHEMBL494885				ZINC40972334	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006824	C1CN=C(N1)C1COc2cccc(-c3ccccc3)c2O1	InChI=1S/C17H16N2O2/c1-2-5-12(6-3-1)13-7-4-8-14-16(13)21-15(11-20-14)17-18-9-10-19-17/h1-8,15H,9-11H2,(H,18,19)	LOGUSYSMQQMCJG-UHFFFAOYSA-N	50412253	CHEMBL522151	Alpha-2C adrenergic receptor					 3162					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412253&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906241	163361277		CHEMBL522151				ZINC40949724	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006825	C1CN=C(N1)C1COc2c(O1)cccc2-c1ccccc1	InChI=1S/C17H16N2O2/c1-2-5-12(6-3-1)13-7-4-8-14-16(13)20-11-15(21-14)17-18-9-10-19-17/h1-8,15H,9-11H2,(H,18,19)	MQSPJCMZCOHHPI-UHFFFAOYSA-N	50412256	CHEMBL493272	Alpha-2C adrenergic receptor					 794					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412256&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906201	163361280		CHEMBL493272				ZINC40431295	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006826	C1CN=C(N1)C(Oc1ccccc1-c1ccccc1)c1ccccc1	InChI=1S/C22H20N2O/c1-3-9-17(10-4-1)19-13-7-8-14-20(19)25-21(22-23-15-16-24-22)18-11-5-2-6-12-18/h1-14,21H,15-16H2,(H,23,24)	XXOSLSPHUHLICG-UHFFFAOYSA-N	50412257	CHEMBL523048	Alpha-2C adrenergic receptor					 776					ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412257&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906200	163361281		CHEMBL523048				ZINC40957110	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51006836	CC(Oc1ccccc1)C1=NCCN1	InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	MDFFTELFADBPIZ-UHFFFAOYSA-N	50412260	CHEMBL273485	Alpha-2C adrenergic receptor		 263								ChEMBL	10.1021/jm800250z	10.7270/Q2HQ4147	18578476			Gentili, F; Cardinaletti, C; Vesprini, C; Carrieri, A; Ghelfi, F; Farande, A; Giannella, M; Piergentili, A; Quaglia, W; Laurila, JM; Huhtinen, A; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412260&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269122	163361284		CHEMBL273485				ZINC13471581	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50519753	C=CCc1ccccc1NCC1=NCCN1	InChI=1S/C13H17N3/c1-2-5-11-6-3-4-7-12(11)16-10-13-14-8-9-15-13/h2-4,6-7,16H,1,5,8-10H2,(H,14,15)	IYFFDNHPGFKOCO-UHFFFAOYSA-N	50193035	CHEMBL3961335	Alpha-2C adrenergic receptor					 158					ChEMBL	10.1021/acsmedchemlett.6b00290	10.7270/Q2086784	27774136			Giusepponi, ME; Cifani, C; Micioni Di Bonaventura, MV; Mattioli, L; Hudson, A; Diamanti, E; Del Bello, F; Giannella, M; Mammoli, V; Paoletti, CD; Piergentili, A; Pigini, M; Quaglia, W	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193035	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193035&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			134156190	375076070		CHEMBL3961335					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50519754	C(Nc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C16H17N3/c1-2-6-13(7-3-1)14-8-4-5-9-15(14)19-12-16-17-10-11-18-16/h1-9,19H,10-12H2,(H,17,18)	RJDGUOVDCSODNG-UHFFFAOYSA-N	50000214	CHEMBL337862	Alpha-2C adrenergic receptor					 148					ChEMBL	10.1021/acsmedchemlett.6b00290	10.7270/Q2086784	27774136			Giusepponi, ME; Cifani, C; Micioni Di Bonaventura, MV; Mattioli, L; Hudson, A; Diamanti, E; Del Bello, F; Giannella, M; Mammoli, V; Paoletti, CD; Piergentili, A; Pigini, M; Quaglia, W	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000214&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352155	242055754		CHEMBL337862					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50519760	Cc1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3/c1-9-4-2-3-5-10(9)14-8-11-12-6-7-13-11/h2-5,14H,6-8H2,1H3,(H,12,13)	WOYZHFHQSIRZAK-UHFFFAOYSA-N	50193034	CHEMBL3904276	Alpha-2C adrenergic receptor					 22					ChEMBL	10.1021/acsmedchemlett.6b00290	10.7270/Q2086784	27774136			Giusepponi, ME; Cifani, C; Micioni Di Bonaventura, MV; Mattioli, L; Hudson, A; Diamanti, E; Del Bello, F; Giannella, M; Mammoli, V; Paoletti, CD; Piergentili, A; Pigini, M; Quaglia, W	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193034	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193034&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			129928082	375076069		CHEMBL3904276					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50519761	CCCc1ccccc1NCC1=NCCN1	InChI=1S/C13H19N3/c1-2-5-11-6-3-4-7-12(11)16-10-13-14-8-9-15-13/h3-4,6-7,16H,2,5,8-10H2,1H3,(H,14,15)	DHKRDPVIPVAAGO-UHFFFAOYSA-N	50193036	CHEMBL3892351	Alpha-2C adrenergic receptor					 115					ChEMBL	10.1021/acsmedchemlett.6b00290	10.7270/Q2086784	27774136			Giusepponi, ME; Cifani, C; Micioni Di Bonaventura, MV; Mattioli, L; Hudson, A; Diamanti, E; Del Bello, F; Giannella, M; Mammoli, V; Paoletti, CD; Piergentili, A; Pigini, M; Quaglia, W	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193036&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			134137108	375076071		CHEMBL3892351					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50519765	Clc1ccccc1NCC1=NCCN1	InChI=1S/C10H12ClN3/c11-8-3-1-2-4-9(8)14-7-10-12-5-6-13-10/h1-4,14H,5-7H2,(H,12,13)	DYFUNGBOKHWQAJ-UHFFFAOYSA-N	50027031	(2-Chloro-phenyl)-(4,5-dihydro-1H-imidazol-2-ylmethyl)-amine::CHEMBL51358	Alpha-2C adrenergic receptor					 224					ChEMBL	10.1021/acsmedchemlett.6b00290	10.7270/Q2086784	27774136			Giusepponi, ME; Cifani, C; Micioni Di Bonaventura, MV; Mattioli, L; Hudson, A; Diamanti, E; Del Bello, F; Giannella, M; Mammoli, V; Paoletti, CD; Piergentili, A; Pigini, M; Quaglia, W	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027031&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			13123534	103936613		CHEMBL51358				ZINC29470302	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51027247	C[C@@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m1/s1	MNMDMCKHXVHLAW-LLVKDONJSA-N	50417342	CHEMBL1276139	Alpha-2C adrenergic receptor		 178								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836302	163366366		CHEMBL1276139				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51027249	CC(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)	SEKAQUSPSDPIAN-UHFFFAOYSA-N	50419878	CHEMBL1956195	Alpha-2C adrenergic receptor					 2					ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419878&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345628	163368902		CHEMBL1956195				ZINC73294767	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51027251	C[C@@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m1/s1	SEKAQUSPSDPIAN-LLVKDONJSA-N	50420341	CHEMBL2089155	Alpha-2C adrenergic receptor					 316					ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420341&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70693375	163369365		CHEMBL2089155					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51027252	C[C@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m0/s1	SEKAQUSPSDPIAN-NSHDSACASA-N	50420342	CHEMBL2089156	Alpha-2C adrenergic receptor					 2					ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70695474	163369366		CHEMBL2089156					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018870	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2C adrenergic receptor		 85								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018871	C[C@@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m1/s1	MNMDMCKHXVHLAW-LLVKDONJSA-N	50417342	CHEMBL1276139	Alpha-2C adrenergic receptor		 178								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836302	163366366		CHEMBL1276139				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018873	CC(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	QYCJTZDZQXSXSC-UHFFFAOYSA-N	50417344	CHEMBL1276218	Alpha-2C adrenergic receptor		 79								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417344&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44549156	163366368		CHEMBL1276218				ZINC64393121	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018874	C[C@@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m1/s1	QYCJTZDZQXSXSC-SNVBAGLBSA-N	50417345	CHEMBL1276219	Alpha-2C adrenergic receptor		 126								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417345&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836304	163366369		CHEMBL1276219					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018876	CC(Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)	IAIZHDGEGFGNMO-UHFFFAOYSA-N	50417347	CHEMBL385310	Alpha-2C adrenergic receptor		 132								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417347&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11371902	163366371		CHEMBL385310				ZINC13585567	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018880	C[C@@H](Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	XGMNRALXOWECNG-GFCCVEGCSA-N	50417351	CHEMBL1278084	Alpha-2C adrenergic receptor		 32								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417351&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836308	163366375		CHEMBL1278084					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018881	C[C@H](Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)/t12-/m0/s1	XGMNRALXOWECNG-LBPRGKRZSA-N	50417352	CHEMBL1278085	Alpha-2C adrenergic receptor		 112								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417352&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836307	163366376		CHEMBL1278085					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018882	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2C adrenergic receptor					 58					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018883	C[C@@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m1/s1	OGOLMGZJNRNULQ-CYBMUJFWSA-N	50417353	CHEMBL242265	Alpha-2C adrenergic receptor					 112					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417353&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11043720	163366377		CHEMBL242265				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018884	C[C@H](Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)/t13-/m0/s1	OGOLMGZJNRNULQ-ZDUSSCGKSA-N	50417354	CHEMBL396013	Alpha-2C adrenergic receptor					 19					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417354&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10333157	163366378		CHEMBL396013				ZINC00009140	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018885	C[C@@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1	NMSAVNXFCXMJJY-GFCCVEGCSA-N	50218115	(R)-2-[1-(3'-nitrobiphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL242693	Alpha-2C adrenergic receptor					 100					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218115&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757089	104091931		CHEMBL242693				ZINC13585593	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018887	C[C@H](Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m0/s1	NMSAVNXFCXMJJY-LBPRGKRZSA-N	50417341	CHEMBL397753	Alpha-2C adrenergic receptor					 741					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417341&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16757182	163366365		CHEMBL397753				ZINC13585595	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018890	C[C@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m0/s1	MNMDMCKHXVHLAW-NSHDSACASA-N	50417343	CHEMBL1276140	Alpha-2C adrenergic receptor					 25					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417343&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836301	163366367		CHEMBL1276140				ZINC40957102	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018893	C[C@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m0/s1	QYCJTZDZQXSXSC-JTQLQIEISA-N	50417346	CHEMBL1276220	Alpha-2C adrenergic receptor					 35					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417346&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836303	163366370		CHEMBL1276220					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018895	C[C@@H](Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)/t11-/m1/s1	IAIZHDGEGFGNMO-LLVKDONJSA-N	50417348	CHEMBL1276247	Alpha-2C adrenergic receptor					 100					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417348&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836306	163366372		CHEMBL1276247					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018896	C[C@H](Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)/t11-/m0/s1	IAIZHDGEGFGNMO-NSHDSACASA-N	50417349	CHEMBL1276248	Alpha-2C adrenergic receptor					 6.3					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417349&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836305	163366373		CHEMBL1276248					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018897	CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)	XGMNRALXOWECNG-UHFFFAOYSA-N	50417350	CHEMBL374584	Alpha-2C adrenergic receptor					 47					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417350&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11346584	163366374		CHEMBL374584				ZINC13585584	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018900	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2C adrenergic receptor					 58					ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51018954	CC(Oc1ccccc1)C1=NCCN1	InChI=1S/C11H14N2O/c1-9(11-12-7-8-13-11)14-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3,(H,12,13)	MDFFTELFADBPIZ-UHFFFAOYSA-N	50412260	CHEMBL273485	Alpha-2C adrenergic receptor		 263								ChEMBL	10.1021/jm100977d	10.7270/Q24B32JF	20925410			Del Bello, F; Mattioli, L; Ghelfi, F; Giannella, M; Piergentili, A; Quaglia, W; Cardinaletti, C; Perfumi, M; Thomas, RJ; Zanelli, U; Marchioro, C; Dal Cin, M; Pigini, M	Universita` di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412260&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269122	163361284		CHEMBL273485				ZINC13471581	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025416	CC(Oc1ccccc1Br)C1=NCCN1	InChI=1S/C11H13BrN2O/c1-8(11-13-6-7-14-11)15-10-5-3-2-4-9(10)12/h2-5,8H,6-7H2,1H3,(H,13,14)	NFGYJBCMYUYKCI-UHFFFAOYSA-N	50419874	CHEMBL1956192	Alpha-2C adrenergic receptor		 282								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419874&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345626	163368898		CHEMBL1956192				ZINC73315479	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025417	CC(Oc1ccccc1C(F)(F)F)C1=NCCN1	InChI=1S/C12H13F3N2O/c1-8(11-16-6-7-17-11)18-10-5-3-2-4-9(10)12(13,14)15/h2-5,8H,6-7H2,1H3,(H,16,17)	BFKLSSIIDDEGQB-UHFFFAOYSA-N	50419875	CHEMBL1956193	Alpha-2C adrenergic receptor		 977								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419875	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419875&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57395663	163368899		CHEMBL1956193				ZINC73314893	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025419	CC(C)c1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H20N2O/c1-10(2)12-6-4-5-7-13(12)17-11(3)14-15-8-9-16-14/h4-7,10-11H,8-9H2,1-3H3,(H,15,16)	DAEHQHNTEAMXQC-UHFFFAOYSA-N	50419876	CHEMBL266613	Alpha-2C adrenergic receptor		 457								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419876&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269089	163368900		CHEMBL266613				ZINC13805985	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025420	CC(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)	SEKAQUSPSDPIAN-UHFFFAOYSA-N	50419878	CHEMBL1956195	Alpha-2C adrenergic receptor		 275								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419878&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345628	163368902		CHEMBL1956195				ZINC73294767	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025421	CCOc1ccccc1OC(C)C1=NCCN1	InChI=1S/C13H18N2O2/c1-3-16-11-6-4-5-7-12(11)17-10(2)13-14-8-9-15-13/h4-7,10H,3,8-9H2,1-2H3,(H,14,15)	DYQQPAOLMYPZKE-UHFFFAOYSA-N	50419879	CHEMBL1956196	Alpha-2C adrenergic receptor		 759								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419879	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419879&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57399145	163368903		CHEMBL1956196				ZINC73312418	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025423	CC(Oc1ccccc1OC1CC1)C1=NCCN1	InChI=1S/C14H18N2O2/c1-10(14-15-8-9-16-14)17-12-4-2-3-5-13(12)18-11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	OHLOMHGVALXPJP-UHFFFAOYSA-N	50419880	CHEMBL1956197	Alpha-2C adrenergic receptor		 676								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419880&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345629	163368904		CHEMBL1956197				ZINC73312422	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025424	CC(Oc1ccccc1S(C)(=O)=O)C1=NCCN1	InChI=1S/C12H16N2O3S/c1-9(12-13-7-8-14-12)17-10-5-3-4-6-11(10)18(2,15)16/h3-6,9H,7-8H2,1-2H3,(H,13,14)	BUVSDNNKXQXCRO-UHFFFAOYSA-N	50419882	CHEMBL1956200	Alpha-2C adrenergic receptor		 3802								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419882	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419882&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57400959	163368906		CHEMBL1956200				ZINC73312436	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025425	CC(Oc1ccccc1C=O)C1=NCCN1	InChI=1S/C12H14N2O2/c1-9(12-13-6-7-14-12)16-11-5-3-2-4-10(11)8-15/h2-5,8-9H,6-7H2,1H3,(H,13,14)	UQOROHPPKUMVNP-UHFFFAOYSA-N	50419883	CHEMBL1956201	Alpha-2C adrenergic receptor		 8710								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419883	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419883&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57402718	163368907		CHEMBL1956201				ZINC73312440	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025426	CC(Oc1ccccc1C(C)=O)C1=NCCN1	InChI=1S/C13H16N2O2/c1-9(16)11-5-3-4-6-12(11)17-10(2)13-14-7-8-15-13/h3-6,10H,7-8H2,1-2H3,(H,14,15)	LHYRGWVECGKEOM-UHFFFAOYSA-N	50419888	CHEMBL1956202	Alpha-2C adrenergic receptor		 7413								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419888&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57395731	163368912		CHEMBL1956202				ZINC73312444	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025427	CC(Oc1c(C)cccc1C)C1=NCCN1	InChI=1S/C13H18N2O/c1-9-5-4-6-10(2)12(9)16-11(3)13-14-7-8-15-13/h4-6,11H,7-8H2,1-3H3,(H,14,15)	JWAAXMLRAVOKBQ-UHFFFAOYSA-N	50419889	CHEMBL155866	Alpha-2C adrenergic receptor		 251								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419889&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371755	163368913		CHEMBL155866				ZINC27710505	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025429	CC(Oc1c(cccc1-c1ccccc1)-c1ccccc1)C1=NCCN1	InChI=1S/C23H22N2O/c1-17(23-24-15-16-25-23)26-22-20(18-9-4-2-5-10-18)13-8-14-21(22)19-11-6-3-7-12-19/h2-14,17H,15-16H2,1H3,(H,24,25)	YCFVUTASHGKCKL-UHFFFAOYSA-N	50419873	CHEMBL1956203	Alpha-2C adrenergic receptor		 631								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419873	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419873&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57395732	163368897		CHEMBL1956203				ZINC73311702	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025456	CCc1ccccc1OC(C)C1=NCCN1	InChI=1S/C13H18N2O/c1-3-11-6-4-5-7-12(11)16-10(2)13-14-8-9-15-13/h4-7,10H,3,8-9H2,1-2H3,(H,14,15)	RUFDXBQFEDFKDE-UHFFFAOYSA-N	50419886	CHEMBL156336	Alpha-2C adrenergic receptor					 100					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419886	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419886&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371745	163368910		CHEMBL156336				ZINC27712342	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025460	CC(C)Oc1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H20N2O2/c1-10(2)17-12-6-4-5-7-13(12)18-11(3)14-15-8-9-16-14/h4-7,10-11H,8-9H2,1-3H3,(H,15,16)	YQBKUZKHVPTFOO-UHFFFAOYSA-N	50419887	CHEMBL14208	Alpha-2C adrenergic receptor					 100					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419887	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419887&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269140	163368911		CHEMBL14208				ZINC13805996	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025462	CC(Oc1ccccc1OC=C)C1=NCCN1	InChI=1S/C13H16N2O2/c1-3-16-11-6-4-5-7-12(11)17-10(2)13-14-8-9-15-13/h3-7,10H,1,8-9H2,2H3,(H,14,15)	OKXLKFXGMFJJAL-UHFFFAOYSA-N	50419891	CHEMBL1956198	Alpha-2C adrenergic receptor					 631					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419891	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419891&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57393922	163368915		CHEMBL1956198				ZINC73312427	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025470	CC(Oc1c(CC=C)cccc1CC=C)C1=NCCN1	InChI=1S/C17H22N2O/c1-4-7-14-9-6-10-15(8-5-2)16(14)20-13(3)17-18-11-12-19-17/h4-6,9-10,13H,1-2,7-8,11-12H2,3H3,(H,18,19)	YAYASQTZIRSRFB-UHFFFAOYSA-N	50419885	CHEMBL157206	Alpha-2C adrenergic receptor					 56					ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419885&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371744	163368909		CHEMBL157206				ZINC27712333	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025488	CC(Oc1c(Cl)cccc1Cl)C1=NCCN1	InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)	KSMAGQUYOIHWFS-UHFFFAOYSA-N	50019646	2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline::2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole::CHEMBL17860::lofexidine	Alpha-2C adrenergic receptor		 69								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019646&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			30668	103930569	51368	CHEMBL17860	DB04948			ZINC00005626	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025500	CC(Oc1ccccc1Cl)C1=NCCN1	InChI=1S/C11H13ClN2O/c1-8(11-13-6-7-14-11)15-10-5-3-2-4-9(10)12/h2-5,8H,6-7H2,1H3,(H,13,14)	ARHDCTCZSSOSFG-UHFFFAOYSA-N	50419890	CHEMBL1956191	Alpha-2C adrenergic receptor		 490								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419890&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345625	163368914		CHEMBL1956191				ZINC73314283	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025501	CC(Oc1ccccc1C(C)=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(2)12-6-4-5-7-13(12)17-11(3)14-15-8-9-16-14/h4-7,11H,1,8-9H2,2-3H3,(H,15,16)	HVCWUSZDSFHZDW-UHFFFAOYSA-N	50419877	CHEMBL1956194	Alpha-2C adrenergic receptor		 603								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419877	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419877&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345627	163368901		CHEMBL1956194				ZINC73313031	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025502	COc1ccccc1OC(C)C1=NCCN1	InChI=1S/C12H16N2O2/c1-9(12-13-7-8-14-12)16-11-6-4-3-5-10(11)15-2/h3-6,9H,7-8H2,1-2H3,(H,13,14)	SQPFWLZXWYXMCI-UHFFFAOYSA-N	50419881	CHEMBL1956199	Alpha-2C adrenergic receptor		 832								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419881&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57402717	163368905		CHEMBL1956199				ZINC73312431	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025503	CCc1cccc(CC)c1OC(C)C1=NCCN1	InChI=1S/C15H22N2O/c1-4-12-7-6-8-13(5-2)14(12)18-11(3)15-16-9-10-17-15/h6-8,11H,4-5,9-10H2,1-3H3,(H,16,17)	OXGCVSXSSWZTMU-UHFFFAOYSA-N	50419884	CHEMBL157955	Alpha-2C adrenergic receptor		 275								ChEMBL	10.1016/j.bmc.2012.01.035	10.7270/Q2TD9ZKT	22341244			Diamanti, E; Del Bello, F; Carbonara, G; Carrieri, A; Fracchiolla, G; Giannella, M; Mammoli, V; Piergentili, A; Pohjanoksa, K; Quaglia, W; Scheinin, M; Pigini, M	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419884&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371864	163368908		CHEMBL157955				ZINC27705893	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025620	C1CN=C(N1)[C@@H]1CO[C@@H](CO1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-17-12(9-16-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12-/m0/s1	MPFNVJVLRBBPHX-RYUDHWBXSA-N	50419925	CHEMBL1956899	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419925	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419925&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57393066	163368949		CHEMBL1956899				ZINC73296457	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025622	C1CN=C(N1)[C@@H]1CO[C@H](CO1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-17-12(9-16-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12+/m1/s1	MPFNVJVLRBBPHX-NEPJUHHUSA-N	50419926	CHEMBL1956901	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419926	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419926&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57399991	163368950		CHEMBL1956901				ZINC73294104	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025623	C1CN=C(N1)[C@H]1CO[C@@H](CO1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-17-12(9-16-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12+/m0/s1	MPFNVJVLRBBPHX-NWDGAFQWSA-N	50419931	CHEMBL1956902	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419931&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57384051	163368955		CHEMBL1956902				ZINC73310317	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025624	C1CN=C(N1)[C@@H]1COC[C@@H](O1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-16-9-12(17-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12+/m1/s1	OQACXTOHBUWXII-NEPJUHHUSA-N	50419927	CHEMBL1956903	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419927	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419927&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57394788	163368951		CHEMBL1956903				ZINC73313925	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025625	C1CN=C(N1)[C@@H]1COC[C@H](O1)c1ccccc1	InChI=1S/C13H16N2O2/c1-2-4-10(5-3-1)11-8-16-9-12(17-11)13-14-6-7-15-13/h1-5,11-12H,6-9H2,(H,14,15)/t11-,12-/m0/s1	OQACXTOHBUWXII-RYUDHWBXSA-N	50419928	CHEMBL1956904	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419928	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419928&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57394789	163368952		CHEMBL1956904				ZINC73313928	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025626	C1CN=C(N1)C1COCC(O1)(c1ccccc1)c1ccccc1	InChI=1S/C19H20N2O2/c1-3-7-15(8-4-1)19(16-9-5-2-6-10-16)14-22-13-17(23-19)18-20-11-12-21-18/h1-10,17H,11-14H2,(H,20,21)	VMIZIRROPNWIIU-UHFFFAOYSA-N	50419930	CHEMBL1956906	Alpha-2C adrenergic receptor		 6166								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419930	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419930&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57401787	163368954		CHEMBL1956906				ZINC73313936	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025629	C1CN=C(N1)C1COc2ccccc2O1	InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)	HPMRFMKYPGXPEP-UHFFFAOYSA-N	50019848	2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan	Alpha-2C adrenergic receptor		 18								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54459	103930771	5862	CHEMBL10316			C10968	ZINC00900630	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51025633	C1CN=C(N1)C1COC(CO1)(c1ccccc1)c1ccccc1	InChI=1S/C19H20N2O2/c1-3-7-15(8-4-1)19(16-9-5-2-6-10-16)14-22-17(13-23-19)18-20-11-12-21-18/h1-10,17H,11-14H2,(H,20,21)	GTRWYVABSCIMJN-UHFFFAOYSA-N	50419929	CHEMBL1956905	Alpha-2C adrenergic receptor		 7413								ChEMBL	10.1016/j.bmc.2012.02.016	10.7270/Q2JW8G5M	22370341			Mammoli, V; Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mattioli, L; Perfumi, M; Piergentili, A; Quaglia, W; Titomanlio, F; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419929	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419929&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57403508	163368953		CHEMBL1956905				ZINC73297098	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020729	CN1CCN(CC1)c1ccc(Nc2cc(C)nc3ccccc23)cc1	InChI=1S/C21H24N4/c1-16-15-21(19-5-3-4-6-20(19)22-16)23-17-7-9-18(10-8-17)25-13-11-24(2)12-14-25/h3-10,15H,11-14H2,1-2H3,(H,22,23)	MKIZKMFJTXEUHC-UHFFFAOYSA-N	50196137	CHEMBL216399::[4-(4-methylpiperazin-1-yl)phenyl]-(2-methylquinolin-4-yl)-amine	Alpha-2C adrenergic receptor		 690.24								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196137&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9923679	104078013		CHEMBL216399				ZINC52961945	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020730	CCc1c(C)nc2CCCCc2c1Nc1ccc(cc1)N1CCN(C)C(C)C1	InChI=1S/C24H34N4/c1-5-21-18(3)25-23-9-7-6-8-22(23)24(21)26-19-10-12-20(13-11-19)28-15-14-27(4)17(2)16-28/h10-13,17H,5-9,14-16H2,1-4H3,(H,25,26)	AWRXNUNJSQSZSP-UHFFFAOYSA-N	50196143	4-(3,4-dimethylpiperazin-1-yl)phenyl]-(3-ethyl-2-methyl-5,6,7,8-tetrahydroquinolin-4-yl)amine::CHEMBL217768	Alpha-2C adrenergic receptor		 109.9								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196143	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196143&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090635	104078019		CHEMBL217768				ZINC52962006	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020731	CC1CN(CCN1C)c1ccc(Nc2c(c(C)nc3ccccc23)-c2ccccc2)cc1	InChI=1S/C28H30N4/c1-20-19-32(18-17-31(20)3)24-15-13-23(14-16-24)30-28-25-11-7-8-12-26(25)29-21(2)27(28)22-9-5-4-6-10-22/h4-16,20H,17-19H2,1-3H3,(H,29,30)	IJXRJXMYHWPNMW-UHFFFAOYSA-N	50196142	CHEMBL218457::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2-methyl-3-phenylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 5								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196142	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196142&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10070896	104078018		CHEMBL218457				ZINC13977224	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020732	CN1CCN(CC1(C)C)c1ccc(Nc2c(C)cnc3ccccc23)cc1	InChI=1S/C23H28N4/c1-17-15-24-21-8-6-5-7-20(21)22(17)25-18-9-11-19(12-10-18)27-14-13-26(4)23(2,3)16-27/h5-12,15H,13-14,16H2,1-4H3,(H,24,25)	RXEIREHXCVZQFP-UHFFFAOYSA-N	50196139	(3-methylquinolin-4-yl)-[4-(3,3,4-trimethylpiperazin-1-yl)phenyl]amine::CHEMBL218679	Alpha-2C adrenergic receptor		 5.4								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196139&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10473701	104078015		CHEMBL218679				ZINC34801110	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020733	CC1CN(CCN1C)c1ccc(Nc2c(C)cnc3ccccc23)cc1	InChI=1S/C22H26N4/c1-16-14-23-21-7-5-4-6-20(21)22(16)24-18-8-10-19(11-9-18)26-13-12-25(3)17(2)15-26/h4-11,14,17H,12-13,15H2,1-3H3,(H,23,24)	TVLLCWBBMXDYLI-UHFFFAOYSA-N	50196131	CHEMBL217202::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(3-methylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 8.49								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196131	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196131&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090622	104078007		CHEMBL217202				ZINC52962005	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020734	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)c(C)ccc23)cc1	InChI=1S/C25H32N4/c1-16-7-12-23-24(18(16)3)26-20(5)19(4)25(23)27-21-8-10-22(11-9-21)29-14-13-28(6)17(2)15-29/h7-12,17H,13-15H2,1-6H3,(H,26,27)/t17-/m1/s1	OFZVRVWUVPCFQQ-QGZVFWFLSA-N	50196145	(R)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine::CHEMBL217567	Alpha-2C adrenergic receptor		 7.69								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196145	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196145&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090623	104078021		CHEMBL217567					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020735	C[C@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)c(C)ccc23)cc1	InChI=1S/C25H32N4/c1-16-7-12-23-24(18(16)3)26-20(5)19(4)25(23)27-21-8-10-22(11-9-21)29-14-13-28(6)17(2)15-29/h7-12,17H,13-15H2,1-6H3,(H,26,27)/t17-/m0/s1	OFZVRVWUVPCFQQ-KRWDZBQOSA-N	50196124	(S)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine::CHEMBL216674	Alpha-2C adrenergic receptor		 83.95								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196124&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090594	104078000		CHEMBL216674				ZINC52961971	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020736	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)ccc23)cc1	InChI=1S/C24H30N4/c1-16-6-11-22-23(14-16)25-19(4)18(3)24(22)26-20-7-9-21(10-8-20)28-13-12-27(5)17(2)15-28/h6-11,14,17H,12-13,15H2,1-5H3,(H,25,26)/t17-/m1/s1	LKVQAMHRWJYSED-QGZVFWFLSA-N	50196125	(R)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7-trimethylquinolin-4-yl)amine::CHEMBL383978	Alpha-2C adrenergic receptor		 8.3								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196125&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090595	104078001		CHEMBL383978					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020737	C[C@H]1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)ccc23)cc1	InChI=1S/C24H30N4/c1-16-6-11-22-23(14-16)25-19(4)18(3)24(22)26-20-7-9-21(10-8-20)28-13-12-27(5)17(2)15-28/h6-11,14,17H,12-13,15H2,1-5H3,(H,25,26)/t17-/m0/s1	LKVQAMHRWJYSED-KRWDZBQOSA-N	50196140	(S)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7-trimethylquinolin-4-yl)amine::CHEMBL217278	Alpha-2C adrenergic receptor		 76.03								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196140&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090624	104078016		CHEMBL217278				ZINC52962028	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020738	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)cc(C)c23)cc1	InChI=1S/C25H32N4/c1-16-13-17(2)24-23(14-16)26-20(5)19(4)25(24)27-21-7-9-22(10-8-21)29-12-11-28(6)18(3)15-29/h7-10,13-14,18H,11-12,15H2,1-6H3,(H,26,27)	ISQPPFGYKGDIHL-UHFFFAOYSA-N	50196148	CHEMBL218730::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,5,7-tetramethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 132.13								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196148&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11741010	104078024		CHEMBL218730				ZINC52971517	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020739	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(Cl)ccc23)cc1	InChI=1S/C23H27ClN4/c1-15-14-28(12-11-27(15)4)20-8-6-19(7-9-20)26-23-16(2)17(3)25-22-13-18(24)5-10-21(22)23/h5-10,13,15H,11-12,14H2,1-4H3,(H,25,26)	QRWKSCTWTCHDII-UHFFFAOYSA-N	50418050	CHEMBL1689423	Alpha-2C adrenergic receptor		 8.3								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50418050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50418050&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10318507	163367074		CHEMBL1689423				ZINC66102877	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020740	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3ccc(F)cc23)cc1	InChI=1S/C23H27FN4/c1-15-14-28(12-11-27(15)4)20-8-6-19(7-9-20)26-23-16(2)17(3)25-22-10-5-18(24)13-21(22)23/h5-10,13,15H,11-12,14H2,1-4H3,(H,25,26)	OGGREUDUNWRXNK-UHFFFAOYSA-N	50196120	CHEMBL216727::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(6-fluoro-2,3-dimethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 16								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196120&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090626	104077996		CHEMBL216727				ZINC52961958	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020741	CN1CCN(CC1)c1ccc(Nc2c(C)cncc2C)cc1	InChI=1S/C18H24N4/c1-14-12-19-13-15(2)18(14)20-16-4-6-17(7-5-16)22-10-8-21(3)9-11-22/h4-7,12-13H,8-11H2,1-3H3,(H,19,20)	BDODJZYHQXXMMX-UHFFFAOYSA-N	50196133	(3,5-dimethyl-pyridin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl]amine::CHEMBL217180	Alpha-2C adrenergic receptor		 769.13								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196133	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196133&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090634	104078009		CHEMBL217180				ZINC52634508	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020742	Cc1nc2ccccc2c(Nc2ccc(NCCN3CCCC3)cc2)c1C	InChI=1S/C23H28N4/c1-17-18(2)25-22-8-4-3-7-21(22)23(17)26-20-11-9-19(10-12-20)24-13-16-27-14-5-6-15-27/h3-4,7-12,24H,5-6,13-16H2,1-2H3,(H,25,26)	QBONYGHVEVRMDD-UHFFFAOYSA-N	50196114	CHEMBL440594::N-(2,3-dimethylquinolin-4-yl)-N'-(2-pyrrolidin-1-ylethyl)benzene-1,4-diamine	Alpha-2C adrenergic receptor		 100								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196114&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090600	104077990		CHEMBL440594				ZINC34801093	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020743	CCc1c(C)nc2c(C)cccc2c1Nc1ccc(cc1)N1CCCN(C)CC1	InChI=1S/C25H32N4/c1-5-22-19(3)26-24-18(2)8-6-9-23(24)25(22)27-20-10-12-21(13-11-20)29-15-7-14-28(4)16-17-29/h6,8-13H,5,7,14-17H2,1-4H3,(H,26,27)	HWDFFRKTRBIVTK-UHFFFAOYSA-N	50196147	(3-ethyl-2,8-dimethylquinolin-4-yl)-[4-(4-methyl-[1,4]diazepan-1-yl)phenyl]amine::CHEMBL386169	Alpha-2C adrenergic receptor		 8.49								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196147&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090628	104078023		CHEMBL386169				ZINC34801087	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020744	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)c(C)nc3ccccc23)cc1	InChI=1S/C24H30N4O/c1-17-21(15-29)23(20-7-5-6-8-22(20)25-17)26-18-9-11-19(12-10-18)28-14-13-27(4)24(2,3)16-28/h5-12,29H,13-16H2,1-4H3,(H,25,26)	AANVRTGJCGRJSR-UHFFFAOYSA-N	50196123	CHEMBL218675::{2-methyl-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 3.8								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196123&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090630	104077999		CHEMBL218675				ZINC34801107	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020745	CC(O)c1c(C)nc2ccccc2c1Nc1ccc(cc1)N1CCN(C)C(C)C1	InChI=1S/C24H30N4O/c1-16-15-28(14-13-27(16)4)20-11-9-19(10-12-20)26-24-21-7-5-6-8-22(21)25-17(2)23(24)18(3)29/h5-12,16,18,29H,13-15H2,1-4H3,(H,25,26)	VIFJNFUXJIBEDW-UHFFFAOYSA-N	50196117	1-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-2-methylquinolin-3-yl}ethanol::CHEMBL217253	Alpha-2C adrenergic receptor		 4.9								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196117&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090631	104077993		CHEMBL217253				ZINC52962008	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020746	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)cnc3ccccc23)cc1	InChI=1S/C23H28N4O/c1-23(2)16-27(13-12-26(23)3)19-10-8-18(9-11-19)25-22-17(15-28)14-24-21-7-5-4-6-20(21)22/h4-11,14,28H,12-13,15-16H2,1-3H3,(H,24,25)	SASCGBIFSTWAKB-UHFFFAOYSA-N	50196118	CHEMBL268217::{4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 6.4								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196118&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10474679	104077994		CHEMBL268217				ZINC34801106	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020747	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(CO)cnc3ccccc23)cc1	InChI=1S/C22H26N4O/c1-16-14-26(12-11-25(16)2)19-9-7-18(8-10-19)24-22-17(15-27)13-23-21-6-4-3-5-20(21)22/h3-10,13,16,27H,11-12,14-15H2,1-2H3,(H,23,24)/t16-/m1/s1	FYGUXILZNQKUCD-MRXNPFEDSA-N	50196116	(R)-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol::CHEMBL217542	Alpha-2C adrenergic receptor		 9.2								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196116&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090602	104077992		CHEMBL217542				ZINC13977226	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020748	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)cnc3cc(Cl)ccc23)cc1	InChI=1S/C23H27ClN4O/c1-23(2)15-28(11-10-27(23)3)19-7-5-18(6-8-19)26-22-16(14-29)13-25-21-12-17(24)4-9-20(21)22/h4-9,12-13,29H,10-11,14-15H2,1-3H3,(H,25,26)	LCLUBKMUZSVUCV-UHFFFAOYSA-N	50196107	CHEMBL216464::{7-chloro-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 5.9								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196107&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10251036	104077983		CHEMBL216464				ZINC34801089	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020749	CC1CN(CCN1C)c1ccc(Nc2c(CO)cnc3ccc(F)cc23)cc1	InChI=1S/C22H25FN4O/c1-15-13-27(10-9-26(15)2)19-6-4-18(5-7-19)25-22-16(14-28)12-24-21-8-3-17(23)11-20(21)22/h3-8,11-12,15,28H,9-10,13-14H2,1-2H3,(H,24,25)	RLNXYUWOYNTOTQ-UHFFFAOYSA-N	50196115	CHEMBL276417::{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-6-fluoroquinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 42.95								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196115&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10317643	104077991		CHEMBL276417				ZINC53059380	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020750	CN1CCN(CC1(C)C)c1ccc(Nc2c(CO)cnc3ccc(F)cc23)cc1	InChI=1S/C23H27FN4O/c1-23(2)15-28(11-10-27(23)3)19-7-5-18(6-8-19)26-22-16(14-29)13-25-21-9-4-17(24)12-20(21)22/h4-9,12-13,29H,10-11,14-15H2,1-3H3,(H,25,26)	KJGIXOOWJYEMMO-UHFFFAOYSA-N	50196108	CHEMBL424917::{6-fluoro-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 50								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196108&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10475736	104077984		CHEMBL424917				ZINC34801088	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020751	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(CO)cnc3ccc(F)cc23)cc1	InChI=1S/C22H25FN4O/c1-15-13-27(10-9-26(15)2)19-6-4-18(5-7-19)25-22-16(14-28)12-24-21-8-3-17(23)11-20(21)22/h3-8,11-12,15,28H,9-10,13-14H2,1-2H3,(H,24,25)/t15-/m1/s1	RLNXYUWOYNTOTQ-OAHLLOKOSA-N	50196127	(R)-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-6-fluoroquinolin-3-yl}methanol::CHEMBL214661	Alpha-2C adrenergic receptor		 38.02								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196127	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196127&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090633	104078003		CHEMBL214661					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020752	CCN1CCN(CC1)c1ccc(Nc2c3ccccc3nc3ccccc23)cc1	InChI=1S/C25H26N4/c1-2-28-15-17-29(18-16-28)20-13-11-19(12-14-20)26-25-21-7-3-5-9-23(21)27-24-10-6-4-8-22(24)25/h3-14H,2,15-18H2,1H3,(H,26,27)	CUVBGWMAORETGV-UHFFFAOYSA-N	50196122	CHEMBL217366::GNF-PF-3878::N-(4-(4-ethylpiperazin-1-yl)phenyl)acridin-9-amine::TCMDC-124255	Alpha-2C adrenergic receptor		 36.98								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196122&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3072540	104077998		CHEMBL217366				ZINC52962012	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020724	CN1CCN(CC1)c1ccc(Nc2c3ccccc3nc3ccccc23)cc1	InChI=1S/C24H24N4/c1-27-14-16-28(17-15-27)19-12-10-18(11-13-19)25-24-20-6-2-4-8-22(20)26-23-9-5-3-7-21(23)24/h2-13H,14-17H2,1H3,(H,25,26)	QZKGUNQLVFEEBA-UHFFFAOYSA-N	50196135	Acridin-9-yl-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine::CHEMBL106525::GNF-Pf-3427::N-(4-(4-methylpiperazin-1-yl)phenyl)acridin-9-amine::TCMDC-123912	Alpha-2C adrenergic receptor		 27.99								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196135	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196135&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			540335	104078011		CHEMBL106525		3930		ZINC53151259	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020725	CN1CCN(CC1)c1ccc(Nc2ccnc3ccccc23)cc1	InChI=1S/C20H22N4/c1-23-12-14-24(15-13-23)17-8-6-16(7-9-17)22-20-10-11-21-19-5-3-2-4-18(19)20/h2-11H,12-15H2,1H3,(H,21,22)	RXXDJBWYJTWSKV-UHFFFAOYSA-N	50196110	CHEMBL217665::GNF-PF-2857::N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::[4-(4-methylpiperazin-1-yl)phenyl]quinolin-4-ylamine	Alpha-2C adrenergic receptor		 1698.24								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196110&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			4567175	104077986		CHEMBL217665				ZINC52962019	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020726	CN1CCN(CC1)c1ccc(Nc2c(C)c(C)nc3ccccc23)cc1	InChI=1S/C22H26N4/c1-16-17(2)23-21-7-5-4-6-20(21)22(16)24-18-8-10-19(11-9-18)26-14-12-25(3)13-15-26/h4-11H,12-15H2,1-3H3,(H,23,24)	YAPCYKZPQAMZQI-UHFFFAOYSA-N	50196141	(2,3-dimethylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl] amine::CHEMBL267464	Alpha-2C adrenergic receptor		 34.99								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196141&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10132386	104078017		CHEMBL267464				ZINC53050145	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020727	CC(C)c1c(C)nc2ccccc2c1Nc1ccc(cc1)N1CCN(C)CC1	InChI=1S/C24H30N4/c1-17(2)23-18(3)25-22-8-6-5-7-21(22)24(23)26-19-9-11-20(12-10-19)28-15-13-27(4)14-16-28/h5-12,17H,13-16H2,1-4H3,(H,25,26)	JLIOUCZCOQHOPO-UHFFFAOYSA-N	50196119	(3-isopropyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)phenyl]amine::CHEMBL425622	Alpha-2C adrenergic receptor		 52								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196119&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10177445	104077995		CHEMBL425622				ZINC53255565	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020728	CN1CCN(CC1)c1ccc(Nc2c(c(C)nc3ccccc23)-c2ccccc2)cc1	InChI=1S/C27H28N4/c1-20-26(21-8-4-3-5-9-21)27(24-10-6-7-11-25(24)28-20)29-22-12-14-23(15-13-22)31-18-16-30(2)17-19-31/h3-15H,16-19H2,1-2H3,(H,28,29)	YRMKSXYNMSJIBT-UHFFFAOYSA-N	50196130	(2-methyl-3-phenylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine::CHEMBL216290	Alpha-2C adrenergic receptor		 34.99								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196130&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10319299	104078006		CHEMBL216290				ZINC52961950	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020753	CCc1c(C)nc2ccccc2c1Nc1ccc(cc1)N1CCN(C)CC1	InChI=1S/C23H28N4/c1-4-20-17(2)24-22-8-6-5-7-21(22)23(20)25-18-9-11-19(12-10-18)27-15-13-26(3)14-16-27/h5-12H,4,13-16H2,1-3H3,(H,24,25)	YEGLCEJPSSYEQE-UHFFFAOYSA-N	50196136	(3-ethyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine::CHEMBL425803	Alpha-2C adrenergic receptor		 25								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196136&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10109188	104078012		CHEMBL425803				ZINC53228274	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020754	CN1CCN(CC1)c1ccc(Nc2c(Cc3ccccc3)c(C)nc3ccccc23)cc1	InChI=1S/C28H30N4/c1-21-26(20-22-8-4-3-5-9-22)28(25-10-6-7-11-27(25)29-21)30-23-12-14-24(15-13-23)32-18-16-31(2)17-19-32/h3-15H,16-20H2,1-2H3,(H,29,30)	CNOXIXMPZLKURQ-UHFFFAOYSA-N	50196128	(3-benzyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine::CHEMBL384925	Alpha-2C adrenergic receptor		 34.99								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196128&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090621	104078004		CHEMBL384925				ZINC53173678	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020755	CN1CCCN(C1)c1ccc(Nc2c(C)c(C)nc3c(C)cccc23)cc1	InChI=1S/C23H28N4/c1-16-7-5-8-21-22(16)24-18(3)17(2)23(21)25-19-9-11-20(12-10-19)27-14-6-13-26(4)15-27/h5,7-12H,6,13-15H2,1-4H3,(H,24,25)	KUMLVCNUFRRWHR-UHFFFAOYSA-N	50196111	4-(3-methyltetrahydropyrimidin-1(2H)-yl)phenyl]-(2,3,8-trimethylquinolin-4-yl)amine::CHEMBL216072	Alpha-2C adrenergic receptor		 5000								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196111&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090599	104077987		CHEMBL216072				ZINC34801117	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020756	Cc1nc2ccccc2c(Nc2ccc(cc2)N2CCN3CCCCC3C2)c1C	InChI=1S/C25H30N4/c1-18-19(2)26-24-9-4-3-8-23(24)25(18)27-20-10-12-21(13-11-20)29-16-15-28-14-6-5-7-22(28)17-29/h3-4,8-13,22H,5-7,14-17H2,1-2H3,(H,26,27)	MZAWJNSMQVUPQW-UHFFFAOYSA-N	50196109	(2,3-dimethylquinolin-4-yl)-[4-(octahydro-2H-pyrido[1,2-a]-pyrazin-2-yl)phenyl]amine::CHEMBL425983	Alpha-2C adrenergic receptor		 2.3								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196109&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10045713	104077985		CHEMBL425983				ZINC53255553	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020757	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)c(C)ccc23)cc1	InChI=1S/C25H32N4/c1-16-7-12-23-24(18(16)3)26-20(5)19(4)25(23)27-21-8-10-22(11-9-21)29-14-13-28(6)17(2)15-29/h7-12,17H,13-15H2,1-6H3,(H,26,27)	OFZVRVWUVPCFQQ-UHFFFAOYSA-N	50196132	CHEMBL217203::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7,8-tetramethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 5								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196132	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196132&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10362866	104078008		CHEMBL217203				ZINC52961985	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020758	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cc(C)ccc23)cc1	InChI=1S/C24H30N4/c1-16-6-11-22-23(14-16)25-19(4)18(3)24(22)26-20-7-9-21(10-8-20)28-13-12-27(5)17(2)15-28/h6-11,14,17H,12-13,15H2,1-5H3,(H,25,26)	LKVQAMHRWJYSED-UHFFFAOYSA-N	50196113	CHEMBL262901::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,7-trimethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 15								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196113&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10044968	104077989		CHEMBL262901				ZINC53033641	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020759	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)cccc23)cc1	InChI=1S/C24H30N4/c1-16-7-6-8-22-23(16)25-19(4)18(3)24(22)26-20-9-11-21(12-10-20)28-14-13-27(5)17(2)15-28/h6-12,17H,13-15H2,1-5H3,(H,25,26)	ONMSNZLMBSAGLW-UHFFFAOYSA-N	50196146	CHEMBL217177::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,8-trimethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 6.9								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196146&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090596	104078022		CHEMBL217177				ZINC52961981	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020760	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3c(C)ccc(C)c23)cc1	InChI=1S/C25H32N4/c1-16-7-8-17(2)24-23(16)25(19(4)20(5)26-24)27-21-9-11-22(12-10-21)29-14-13-28(6)18(3)15-29/h7-12,18H,13-15H2,1-6H3,(H,26,27)	KTKKHYOEEDBCLW-UHFFFAOYSA-N	50196112	CHEMBL384318::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,5,8-tetramethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 389.94								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196112&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090597	104077988		CHEMBL384318				ZINC53173617	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020761	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cccc(Cl)c23)cc1	InChI=1S/C23H27ClN4/c1-15-14-28(13-12-27(15)4)19-10-8-18(9-11-19)26-23-16(2)17(3)25-21-7-5-6-20(24)22(21)23/h5-11,15H,12-14H2,1-4H3,(H,25,26)	DZQRMYQZZBIVHO-UHFFFAOYSA-N	50196138	(5-chloro-2,3-dimethylquinolin-4-yl)-[4-(3,4-dimethylpiperazin-1-yl)phenyl]amine::CHEMBL217568	Alpha-2C adrenergic receptor		 134.9								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196138&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090598	104078014		CHEMBL217568				ZINC52961987	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020762	CCN(CC)CCNc1ccc(Nc2c(CC)c(C)nc3c(C)cccc23)cc1	InChI=1S/C25H34N4/c1-6-22-19(5)27-24-18(4)10-9-11-23(24)25(22)28-21-14-12-20(13-15-21)26-16-17-29(7-2)8-3/h9-15,26H,6-8,16-17H2,1-5H3,(H,27,28)	VWHNYSUZLOHFTG-UHFFFAOYSA-N	50196106	CHEMBL216197::N-(2-diethylaminoethyl)-N'-(3-ethyl-2,8-dimethylquinolin-4-yl)benzene-1,4-diamine	Alpha-2C adrenergic receptor		 82.04								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196106&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090627	104077982		CHEMBL216197				ZINC34801115	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020763	CC1CN(CCN1C)c1ccc(Nc2c(CO)c(C)nc3ccccc23)cc1	InChI=1S/C23H28N4O/c1-16-14-27(13-12-26(16)3)19-10-8-18(9-11-19)25-23-20-6-4-5-7-22(20)24-17(2)21(23)15-28/h4-11,16,28H,12-15H2,1-3H3,(H,24,25)	BSEZBDDBKUJHQP-UHFFFAOYSA-N	50196129	CHEMBL214996::{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-2-methylquinolin-3-yl}methanol	Alpha-2C adrenergic receptor		 7.5								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196129&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10045088	104078005		CHEMBL214996				ZINC52961856	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020764	C[C@@H]1CN(CCN1C)c1ccc(Nc2c(C)c(CO)nc3ccccc23)cc1	InChI=1S/C23H28N4O/c1-16-14-27(13-12-26(16)3)19-10-8-18(9-11-19)24-23-17(2)22(15-28)25-21-7-5-4-6-20(21)23/h4-11,16,28H,12-15H2,1-3H3,(H,24,25)/t16-/m1/s1	CWSVSBNTQJZFGE-MRXNPFEDSA-N	50196126	(R)-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-3-methylquinolin-2-yl}methanol::CHEMBL217254	Alpha-2C adrenergic receptor		 9								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196126&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090601	104078002		CHEMBL217254				ZINC52962010	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020765	C[C@@H]1CN(CCN1)c1ccc(Nc2c(CO)cnc3ccccc23)cc1	InChI=1S/C21H24N4O/c1-15-13-25(11-10-22-15)18-8-6-17(7-9-18)24-21-16(14-26)12-23-20-5-3-2-4-19(20)21/h2-9,12,15,22,26H,10-11,13-14H2,1H3,(H,23,24)/t15-/m1/s1	MDMIXTNJRVJFQM-OAHLLOKOSA-N	50196134	(R)-{4-[4-(3-methylpiperazin-1-yl)phenylamino]quinolin-3-yl}methanol::CHEMBL385722	Alpha-2C adrenergic receptor		 205.12								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196134	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196134&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090632	104078010		CHEMBL385722				ZINC53173570	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51020766	CC1CN(CCN1C)c1ccc(Nc2c(C)c(C)nc3cccc(C)c23)cc1	InChI=1S/C24H30N4/c1-16-7-6-8-22-23(16)24(18(3)19(4)25-22)26-20-9-11-21(12-10-20)28-14-13-27(5)17(2)15-28/h6-12,17H,13-15H2,1-5H3,(H,25,26)	JLEBPSNYUGYMNN-UHFFFAOYSA-N	50196121	CHEMBL217452::[4-(3,4-dimethylpiperazin-1-yl)phenyl]-(2,3,5-trimethylquinolin-4-yl)amine	Alpha-2C adrenergic receptor		 87.1								ChEMBL	10.1016/j.ejmech.2010.12.026	10.7270/Q2474C44	21277656			Borota, A; Mracec, M; Gruia, A; Rad-Curpan, R; Ostopovici-Halip, L; Mracec, M	Timisoara of the Romanian Academy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196121&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			16090625	104077997		CHEMBL217452				ZINC52962030	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51027232	C[C@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m0/s1	MNMDMCKHXVHLAW-NSHDSACASA-N	50417343	CHEMBL1276140	Alpha-2C adrenergic receptor		 71								ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417343&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836301	163366367		CHEMBL1276140				ZINC40957102	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51027245	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2C adrenergic receptor					 50					ChEMBL	10.1021/ml300064v	10.7270/Q28W3FK6	24900506			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Benedetti, G; Varrone, M; Pigini, M	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50594499	C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1	InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1	CFUHKRLMDNFZED-SFTDATJTSA-N	50370569	A-349,821::A-349821	Alpha-2C adrenergic receptor		 1622								ChEMBL	10.1016/s0960-894x(03)00118-5	10.7270/Q2HM59NM	12657274			Faghih, R; Dwight, W; Pan, JB; Fox, GB; Krueger, KM; Esbenshade, TA; McVey, JM; Marsh, K; Bennani, YL; Hancock, AA	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370569	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370569&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44275807	160849671						ZINC28761941	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564055	Cc1c(ccc2nccnc12)N=C1NCCN1	InChI=1S/C12H13N5/c1-8-9(17-12-15-6-7-16-12)2-3-10-11(8)14-5-4-13-10/h2-5H,6-7H2,1H3,(H2,15,16,17)	QZUXRMOPAGPTIY-UHFFFAOYSA-N	50052880	CHEMBL49137::Imidazolidin-2-ylidene-(5-methyl-quinoxalin-6-yl)-amine	Alpha-2C adrenergic receptor		 28								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052880&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			185076	103949620		CHEMBL49137				ZINC05159693	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564071	Brc1c(NC2=NCCO2)ccc2nccnc12	InChI=1S/C11H9BrN4O/c12-9-7(16-11-15-5-6-17-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H,15,16)	HBHGSUXQIQVLPX-UHFFFAOYSA-N	50213346	CHEMBL73164	Alpha-2C adrenergic receptor		 48978								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213346&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44312198	376070926		CHEMBL73164					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564074	C1CN=C(Nc2ccc3nccnc3c2)N1	InChI=1S/C11H11N5/c1-2-9-10(13-4-3-12-9)7-8(1)16-11-14-5-6-15-11/h1-4,7H,5-6H2,(H2,14,15,16)	PVKUNRLEOHFACD-UHFFFAOYSA-N	50213029	CHEMBL49395	Alpha-2C adrenergic receptor		 1413								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213029	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213029&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10198248	376070774		CHEMBL49395					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564249	Cc1cnc2c(Br)c(NC3=NCCN3)ccc2n1	InChI=1S/C12H12BrN5/c1-7-6-16-11-9(17-7)3-2-8(10(11)13)18-12-14-4-5-15-12/h2-3,6H,4-5H2,1H3,(H2,14,15,18)	ICROYPJYNVAMQF-UHFFFAOYSA-N	50213351	CHEMBL72147	Alpha-2C adrenergic receptor		 646								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213351&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			15675860	376070931		CHEMBL72147					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564257	Brc1c(NC2=NCCN2)ccc2NCCNc12	InChI=1S/C11H14BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-2,13-14H,3-6H2,(H2,15,16,17)	CETMNKCDAHCKRC-UHFFFAOYSA-N	50213028	CHEMBL74283	Alpha-2C adrenergic receptor					 105					ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213028	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213028&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			131829	376070773		CHEMBL74283					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50564260	Brc1c(NC2=N[C@@H]3CCCC[C@@H]3N2)ccc2nccnc12	InChI=1S/C15H16BrN5/c16-13-11(5-6-12-14(13)18-8-7-17-12)21-15-19-9-3-1-2-4-10(9)20-15/h5-10H,1-4H2,(H2,19,20,21)/t9-,10+	MIYQUCZRQJRHHG-AOOOYVTPSA-N	50213349	CHEMBL74342	Alpha-2C adrenergic receptor		 11482								ChEMBL		10.7270/Q2DV1N3J				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213349&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311789	376070929		CHEMBL74342					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561153	C1CN=C(O1)N1CCOCC1	InChI=1S/C7H12N2O2/c1-4-11-7(8-1)9-2-5-10-6-3-9/h1-6H2	ICFHSWCDTICIIC-UHFFFAOYSA-N	50212994	CHEMBL75201	Alpha-2C adrenergic receptor		 16596								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212994&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			21392988	376070739		CHEMBL75201					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561155	C1CC1C(NC1=NCCO1)C1CC1	InChI=1S/C10H16N2O/c1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10/h7-9H,1-6H2,(H,11,12)	CQXADFVORZEARL-UHFFFAOYSA-N	50070328	CHEBI:8862::Rilmenidine	Alpha-2C adrenergic receptor		 288								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070328&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68712	313072381					C11120		1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561181	CCC[C@H]1CCCCC1NC1=NCCO1	InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11?/m0/s1	WDSZUSABLKNHCZ-VUWPPUDQSA-N	50212997	CHEMBL310335	Alpha-2C adrenergic receptor		 25								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212997	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212997&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314198	376070742		CHEMBL310335					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561185	C1COC(NC2CCCc3ccccc23)=NC1	InChI=1S/C14H18N2O/c1-2-7-12-11(5-1)6-3-8-13(12)16-14-15-9-4-10-17-14/h1-2,5,7,13H,3-4,6,8-10H2,(H,15,16)	LAMFPOWZDAOQTK-UHFFFAOYSA-N	50212996	CHEMBL306377	Alpha-2C adrenergic receptor		 85								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212996&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314200	376070741		CHEMBL306377					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561197	C1CN=C(NC2CCCCCC2)O1	InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)	DAIRUBYTBODIKT-UHFFFAOYSA-N	50212993	CHEMBL305928	Alpha-2C adrenergic receptor		 33								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212993&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			294234	376070738		CHEMBL305928					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561202	C1CN=C(NC2CCCc3ccccc23)O1	InChI=1S/C13H16N2O/c1-2-6-11-10(4-1)5-3-7-12(11)15-13-14-8-9-16-13/h1-2,4,6,12H,3,5,7-9H2,(H,14,15)	FXNNPMSELIMMHU-UHFFFAOYSA-N	50212995	CHEMBL75030	Alpha-2C adrenergic receptor		 12								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212995&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			218362	376070740		CHEMBL75030					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561210	C1CN=C(NC2CCCCCC2)O1	InChI=1S/C10H18N2O/c1-2-4-6-9(5-3-1)12-10-11-7-8-13-10/h9H,1-8H2,(H,11,12)	DAIRUBYTBODIKT-UHFFFAOYSA-N	50212993	CHEMBL305928	Alpha-2C adrenergic receptor					 78					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212993&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			294234	376070738		CHEMBL305928					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561212	C1CC1C(NC1=NCCO1)C1CC1	InChI=1S/C10H16N2O/c1-2-7(1)9(8-3-4-8)12-10-11-5-6-13-10/h7-9H,1-6H2,(H,11,12)	CQXADFVORZEARL-UHFFFAOYSA-N	50070328	CHEBI:8862::Rilmenidine	Alpha-2C adrenergic receptor					 191					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070328&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			68712	313072381					C11120		1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561213	CCC[C@H]1CCCCC1NC1=NCCO1	InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11?/m0/s1	WDSZUSABLKNHCZ-VUWPPUDQSA-N	50212997	CHEMBL310335	Alpha-2C adrenergic receptor					 4.1					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212997	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212997&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314198	376070742		CHEMBL310335					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561221	C1COC(NC2CCCc3ccccc23)=NC1	InChI=1S/C14H18N2O/c1-2-7-12-11(5-1)6-3-8-13(12)16-14-15-9-4-10-17-14/h1-2,5,7,13H,3-4,6,8-10H2,(H,15,16)	LAMFPOWZDAOQTK-UHFFFAOYSA-N	50212996	CHEMBL306377	Alpha-2C adrenergic receptor					 25					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212996&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314200	376070741		CHEMBL306377					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561224	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2C adrenergic receptor		 56								ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561225	Clc1cccc(Cl)c1N=C1NCCN1	InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	GJSURZIOUXUGAL-UHFFFAOYSA-N	50016897	2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)	Alpha-2C adrenergic receptor					 55					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	CLU	2PNC,7AWW	2803	103928231	46632			516		ZINC00896484	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50561233	C1CN=C(NC2CCCc3ccccc23)O1	InChI=1S/C13H16N2O/c1-2-6-11-10(4-1)5-3-7-12(11)15-13-14-8-9-16-13/h1-2,4,6,12H,3,5,7-9H2,(H,14,15)	FXNNPMSELIMMHU-UHFFFAOYSA-N	50212995	CHEMBL75030	Alpha-2C adrenergic receptor					 2.2					ChEMBL		10.7270/Q2GQ70ZD				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212995&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			218362	376070740		CHEMBL75030					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50533203	CN1CC[C@H]2CC(=O)[C@H](Cc3ccccc3)[C@H]3CCC[C@@H]1[C@H]23	InChI=1S/C20H27NO/c1-21-11-10-15-13-19(22)17(12-14-6-3-2-4-7-14)16-8-5-9-18(21)20(15)16/h2-4,6-7,15-18,20H,5,8-13H2,1H3/t15-,16+,17+,18+,20+/m0/s1	HWGSTWOVRDYFSO-VAVNGKDRSA-N	50204312	CHEMBL3936289	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1016/j.bmcl.2016.10.065	10.7270/Q25H7J7R	27839919			McLeod, MC; Aubé, J; Frankowski, KJ	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204312&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			134149168	375980472		CHEMBL3936289					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50533380	CCCN1CC[C@@H]2[C@@H]3[C@H](CCC[C@@H]13)[C@@H](CC)c1nc3cc(ccc3cc21)C(F)(F)F	InChI=1S/C25H31F3N2/c1-3-11-30-12-10-19-20-13-15-8-9-16(25(26,27)28)14-21(15)29-24(20)17(4-2)18-6-5-7-22(30)23(18)19/h8-9,13-14,17-19,22-23H,3-7,10-12H2,1-2H3/t17-,18-,19+,22-,23+/m1/s1	LILDBTJYRFAMFE-VCSLONGPSA-N	50204306	CHEMBL3897499	Alpha-2C adrenergic receptor		 1036								ChEMBL	10.1016/j.bmcl.2016.10.065	10.7270/Q25H7J7R	27839919			McLeod, MC; Aubé, J; Frankowski, KJ	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204306&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132584404	375980466		CHEMBL3897499					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50740195	CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC)nc(nc12)C#Cc1ccc(Cl)s1	InChI=1S/C18H17ClN6O4S/c1-20-15-11-16(24-10(23-15)6-4-8-3-5-9(19)30-8)25(7-22-11)18-13(27)12(26)14(29-18)17(28)21-2/h3,5,7,12-14,18,26-27H,1-2H3,(H,21,28)(H,20,23,24)/t12-,13+,14-,18+/m0/s1	MTSSGMWKEDEGAV-MOROJQBDSA-N	50236785	CHEMBL4090355	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1021/acs.jmedchem.7b00141	10.7270/Q2Z60RBZ	28319392			Tosh, DK; Janowsky, A; Eshleman, AJ; Warnick, E; Gao, ZG; Chen, Z; Gizewski, E; Auchampach, JA; Salvemini, D; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236785	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236785&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			137643541	385453339		CHEMBL4090355					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50740200	CNc1nc(nc2n(cnc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)C(=O)OC)C#Cc1ccc(Cl)s1	InChI=1S/C18H16ClN5O5S/c1-20-15-11-16(23-10(22-15)6-4-8-3-5-9(19)30-8)24(7-21-11)17-13(26)12(25)14(29-17)18(27)28-2/h3,5,7,12-14,17,25-26H,1-2H3,(H,20,22,23)/t12-,13+,14-,17+/m0/s1	QHRWVXZCSCFZGP-QDEZUTFSSA-N	50236726	CHEMBL4092411	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1021/acs.jmedchem.7b00141	10.7270/Q2Z60RBZ	28319392			Tosh, DK; Janowsky, A; Eshleman, AJ; Warnick, E; Gao, ZG; Chen, Z; Gizewski, E; Auchampach, JA; Salvemini, D; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236726&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			137653203	385453330		CHEMBL4092411					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50740629	CCCNc1nc(nc2n(cnc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NC)C#Cc1ccc(Cl)s1	InChI=1S/C20H21ClN6O4S/c1-3-8-23-17-13-18(26-12(25-17)7-5-10-4-6-11(21)32-10)27(9-24-13)20-15(29)14(28)16(31-20)19(30)22-2/h4,6,9,14-16,20,28-29H,3,8H2,1-2H3,(H,22,30)(H,23,25,26)/t14-,15+,16-,20+/m0/s1	VVAIUXGEZUTKDN-KSVNGYGVSA-N	50236779	CHEMBL4086593	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1021/acs.jmedchem.7b00141	10.7270/Q2Z60RBZ	28319392			Tosh, DK; Janowsky, A; Eshleman, AJ; Warnick, E; Gao, ZG; Chen, Z; Gizewski, E; Auchampach, JA; Salvemini, D; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236779&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			137641762	385453337		CHEMBL4086593					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50731942	C1Oc2cc3CCNCc3cc2O1	InChI=1S/C10H11NO2/c1-2-11-5-8-4-10-9(3-7(1)8)12-6-13-10/h3-4,11H,1-2,5-6H2	JHLDJOBIUVJSTG-UHFFFAOYSA-N	50236732	CHEMBL4091137	Alpha-2C adrenergic receptor		<100								ChEMBL	10.1021/acs.jmedchem.7b00085	10.7270/Q2DJ5HWM	28244748			Glennon, RA	Virginia Commonwealth University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236732&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			27013	385213408		CHEMBL4091137					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50732374	O.CS(O)(=O)=O.COc1ccc2n(cc(CN3CCN(C)CC3)c2c1)S(=O)(=O)c1ccccc1Br	InChI=1S/C21H24BrN3O3S/c1-23-9-11-24(12-10-23)14-16-15-25(20-8-7-17(28-2)13-18(16)20)29(26,27)21-6-4-3-5-19(21)22/h3-8,13,15H,9-12,14H2,1-2H3	GWCYPEHWIZXYFZ-UHFFFAOYSA-N	50236754	CHEMBL4082473	Alpha-2C adrenergic receptor		 619								ChEMBL	10.1021/acs.jmedchem.6b01662	10.7270/Q27S7R1X	28212021			Nirogi, R; Shinde, A; Kambhampati, RS; Mohammed, AR; Saraf, SK; Badange, RK; Bandyala, TR; Bhatta, V; Bojja, K; Reballi, V; Subramanian, R; Benade, V; Palacharla, RC; Bhyrapuneni, G; Jayarajan, P; Goyal, V; Jasti, V	Suven Life Sciences Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236754&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			137647199	385213428		CHEMBL4082473					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50808913	Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1	InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21)	OGJGQVFWEPNYSB-UHFFFAOYSA-N	85093	CAS_3853::CHEMBL267014::CHEMBL555670::L 745,870::NSC_3853	Alpha-2C adrenergic receptor		 230								ChEMBL	10.1021/acs.jmedchem.7b00151	10.7270/Q2P84FBZ	28489950			Lindsley, CW; Hopkins, CR	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85093	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85093&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	L74	6IQL	5311200	136351193		CHEMBL555670CHEMBL267014		3303		ZINC25760037	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50808915	Cc1ccc(cc1C)N1CCN(Cc2nc3ccccc3[nH]2)CC1	InChI=1S/C20H24N4/c1-15-7-8-17(13-16(15)2)24-11-9-23(10-12-24)14-20-21-18-5-3-4-6-19(18)22-20/h3-8,13H,9-12,14H2,1-2H3,(H,21,22)	SAQMCVDGOIRQTC-UHFFFAOYSA-N	50150141	2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1H-benzoimidazole::CHEMBL127257	Alpha-2C adrenergic receptor		 1912								ChEMBL	10.1021/acs.jmedchem.7b00151	10.7270/Q2P84FBZ	28489950			Lindsley, CW; Hopkins, CR	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150141&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11301655	104038647		CHEMBL127257				ZINC13581153	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50808976	C(C1Cc2ccccc2C1)N1CCN(CC1)c1ccc2OCCOc2c1	InChI=1S/C22H26N2O2/c1-2-4-19-14-17(13-18(19)3-1)16-23-7-9-24(10-8-23)20-5-6-21-22(15-20)26-12-11-25-21/h1-6,15,17H,7-14,16H2	CYPJMEGEBKHODC-UHFFFAOYSA-N	50257038	CHEMBL146556::S-18126	Alpha-2C adrenergic receptor		 336								ChEMBL	10.1021/acs.jmedchem.7b00151	10.7270/Q2P84FBZ	28489950			Lindsley, CW; Hopkins, CR	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257038	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257038&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9884781	402360945							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50809232	C[C@H]1C[C@@H](C)CN(CCCNC(=O)C2CCN(Cc3nc(oc3C)-c3c(C)cccc3Cl)CC2)C1	InChI=1S/C28H41ClN4O2/c1-19-15-20(2)17-33(16-19)12-6-11-30-27(34)23-9-13-32(14-10-23)18-25-22(4)35-28(31-25)26-21(3)7-5-8-24(26)29/h5,7-8,19-20,23H,6,9-18H2,1-4H3,(H,30,34)/t19-,20+	SHKOYYABTMCHBH-BGYRXZFFSA-N	50257088	CHEMBL4066784	Alpha-2C adrenergic receptor		 575								ChEMBL	10.1021/acs.jmedchem.7b00561	10.7270/Q2DR2XXZ	28636348			He, S; Li, K; Lin, B; Hu, Z; Xiao, J; Hu, X; Wang, AQ; Xu, X; Ferrer, M; Southall, N; Zheng, W; Aubé, J; Schoenen, FJ; Marugan, JJ; Liang, TJ; Frankowski, KJ	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257088	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257088&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70789640	402360968							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796244	COCCNc1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccccc2C1	InChI=1S/C22H29N5O2/c1-29-13-9-23-22-24-14-19(15-25-22)21(28)26-11-7-20(8-12-26)27-10-6-17-4-2-3-5-18(17)16-27/h2-5,14-15,20H,6-13,16H2,1H3,(H,23,24,25)	SEVDIPRRSBFFJZ-UHFFFAOYSA-N	398507	US10323020, Example 1::[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl]{2-[(2-methoxyethyl)amino]pyrimidin-5-yl}methanone	Alpha-2C adrenergic receptor			 82.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398507&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191043	405258559							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796245	CCC(COC)Nc1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccc(F)cc2C1	InChI=1S/C24H32FN5O2/c1-3-21(16-32-2)28-24-26-13-19(14-27-24)23(31)29-10-7-22(8-11-29)30-9-6-17-4-5-20(25)12-18(17)15-30/h4-5,12-14,21-22H,3,6-11,15-16H2,1-2H3,(H,26,27,28)	IPQNIVVBRMLNAV-UHFFFAOYSA-N	398508	(rac)-[4-(7-Fluoro-3,4-dihydroisoquinolin-2(1H)-yl)piperidin-1-yl]{2-[(1-methoxybutan-2-yl)amino]pyrimidin-5-yl}methanone::US10323020, Example 2::US10323020, Example 3	Alpha-2C adrenergic receptor			 26.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398508&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191102	405258560							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796246	CCC(COC)Nc1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccc(F)cc2C1	InChI=1S/C24H32FN5O2/c1-3-21(16-32-2)28-24-26-13-19(14-27-24)23(31)29-10-7-22(8-11-29)30-9-6-17-4-5-20(25)12-18(17)15-30/h4-5,12-14,21-22H,3,6-11,15-16H2,1-2H3,(H,26,27,28)	IPQNIVVBRMLNAV-UHFFFAOYSA-N	398508	(rac)-[4-(7-Fluoro-3,4-dihydroisoquinolin-2(1H)-yl)piperidin-1-yl]{2-[(1-methoxybutan-2-yl)amino]pyrimidin-5-yl}methanone::US10323020, Example 2::US10323020, Example 3	Alpha-2C adrenergic receptor			 24.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398508&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191102	405258560							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796247	CCC(COC)Nc1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccc(OC)cc2C1	InChI=1S/C25H35N5O3/c1-4-21(17-32-2)28-25-26-14-20(15-27-25)24(31)29-11-8-22(9-12-29)30-10-7-18-5-6-23(33-3)13-19(18)16-30/h5-6,13-15,21-22H,4,7-12,16-17H2,1-3H3,(H,26,27,28)	ABXSKFQJDIZFGU-UHFFFAOYSA-N	398510	(rac)-{2-[(1-Methoxybutan-2-yl)amino]pyrimidin-5-yl}[4-(7-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)piperidin-1-yl]methanone::US10323020, Example 4	Alpha-2C adrenergic receptor			 5.00							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398510	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398510&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191147	405258561							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796248	CCC(COC)Nc1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2cc(OC)ccc2C1	InChI=1S/C25H35N5O3/c1-4-21(17-32-2)28-25-26-14-20(15-27-25)24(31)29-11-8-22(9-12-29)30-10-7-18-13-23(33-3)6-5-19(18)16-30/h5-6,13-15,21-22H,4,7-12,16-17H2,1-3H3,(H,26,27,28)	SYKNVCISZXJFCY-UHFFFAOYSA-N	398511	(rac)-{2-[(1-Methoxybutan-2-yl)amino]pyrimidin-5-yl}[4-(6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)piperidin-1-yl]methanone::US10323020, Example 5	Alpha-2C adrenergic receptor			 20.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398511	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398511&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			122652620	405258562							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796249	CCC(COC)Nc1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccccc2C1	InChI=1S/C24H33N5O2/c1-3-21(17-31-2)27-24-25-14-20(15-26-24)23(30)28-12-9-22(10-13-28)29-11-8-18-6-4-5-7-19(18)16-29/h4-7,14-15,21-22H,3,8-13,16-17H2,1-2H3,(H,25,26,27)	GQFYQZJGTFHHLG-UHFFFAOYSA-N	398512	(rac)-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl]{2-[(1-methoxybutan-2-yl)amino]pyrimidin-5-yl}methanone::US10323020, Example 6	Alpha-2C adrenergic receptor			 31.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398512	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398512&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191195	405258563							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796250	CCC(CO)Nc1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccccc2C1	InChI=1S/C23H31N5O2/c1-2-20(16-29)26-23-24-13-19(14-25-23)22(30)27-11-8-21(9-12-27)28-10-7-17-5-3-4-6-18(17)15-28/h3-6,13-14,20-21,29H,2,7-12,15-16H2,1H3,(H,24,25,26)	JUDQBCCVUKHJJW-UHFFFAOYSA-N	398513	(rac)-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl]{2-[(1-hydroxybutan-2-yl)amino]pyrimidin-5-yl}methanone::US10323020, Example 7	Alpha-2C adrenergic receptor			 68.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398513&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191148	405258564							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796251	O=C(N1CCC(CC1)N1CCc2ccccc2C1)c1cnc(nc1)N1CC2(COC2)C1	InChI=1S/C24H29N5O2/c30-22(20-11-25-23(26-12-20)29-14-24(15-29)16-31-17-24)27-9-6-21(7-10-27)28-8-5-18-3-1-2-4-19(18)13-28/h1-4,11-12,21H,5-10,13-17H2	QFUYPQVPOWDETM-UHFFFAOYSA-N	398514	US10323020, Example 8::[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl][2-(2-oxa-6-azaspiro[3.3]hept-6-yl)pyrimidin-5-yl]methanone	Alpha-2C adrenergic receptor			 23.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398514	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398514&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			91810363	405258565							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796252	Fc1ccc2CCN(Cc2c1)C1CCN(CC1)C(=O)c1cnc(nc1)N1CC2(COC2)C1	InChI=1S/C24H28FN5O2/c25-20-2-1-17-3-6-29(12-18(17)9-20)21-4-7-28(8-5-21)22(31)19-10-26-23(27-11-19)30-13-24(14-30)15-32-16-24/h1-2,9-11,21H,3-8,12-16H2	JOKPSSXSXFRNNT-UHFFFAOYSA-N	398515	US10323020, Example 9::[4-(7-Fluoro-3,4-dihydroisoquinolin-2(1H)-yl)piperidin-1-yl][2-(2-oxa-6-azaspiro[3.3]hept-6-yl)pyrimidin-5-yl]methanone	Alpha-2C adrenergic receptor			 16.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191176	405258566							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796253	COc1ccc2CN(CCc2c1)C1CCN(CC1)C(=O)c1cnc(nc1)N1CC2(COC2)C1	InChI=1S/C25H31N5O3/c1-32-22-3-2-19-13-29(7-4-18(19)10-22)21-5-8-28(9-6-21)23(31)20-11-26-24(27-12-20)30-14-25(15-30)16-33-17-25/h2-3,10-12,21H,4-9,13-17H2,1H3	OZTRCMSMHPRTRL-UHFFFAOYSA-N	398516	US10323020, Example 10::[4-(6-Methoxy-3,4-dihydroisoquinolin-2(1H)-yl)piperidin-1-yl][2-(2-oxa-6-azaspiro[3.3]hept-6-yl)pyrimidin-5-yl]methanone	Alpha-2C adrenergic receptor			 30.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398516	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398516&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191177	405258567							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796254	OC(=O)[C@H]1CCCN1c1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccccc2C1	InChI=1S/C24H29N5O3/c30-22(19-14-25-24(26-15-19)29-10-3-6-21(29)23(31)32)27-12-8-20(9-13-27)28-11-7-17-4-1-2-5-18(17)16-28/h1-2,4-5,14-15,20-21H,3,6-13,16H2,(H,31,32)/t21-/m1/s1	QDNVKECOFRDQRW-OAQYLSRUSA-N	398517	1-(5-{[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl]carbonyl}pyrimidin-2-yl)-D-proline Hydrochloride::US10323020, Example 11	Alpha-2C adrenergic receptor			 96.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398517&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118164155	405258568							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796255	O=C(N1CCC(CC1)N1CCc2ccccc2C1)c1cnc(nc1)N1CCS(=O)(=O)CC1	InChI=1S/C23H29N5O3S/c29-22(20-15-24-23(25-16-20)27-11-13-32(30,31)14-12-27)26-9-6-21(7-10-26)28-8-5-18-3-1-2-4-19(18)17-28/h1-4,15-16,21H,5-14,17H2	DOQLTUNASFTORE-UHFFFAOYSA-N	398518	US10323020, Example 12::[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl][2-(1,1-dioxidothiomorpholin-4-yl)pyrimidin-5-yl]methanone	Alpha-2C adrenergic receptor			 26.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398518&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191006	405258569							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796256	CC1CN(CC(C)O1)c1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccccc2C1	InChI=1S/C25H33N5O2/c1-18-15-30(16-19(2)32-18)25-26-13-22(14-27-25)24(31)28-11-8-23(9-12-28)29-10-7-20-5-3-4-6-21(20)17-29/h3-6,13-14,18-19,23H,7-12,15-17H2,1-2H3	BMYFKCKNBYKSDB-UHFFFAOYSA-N	398519	US10323020, Example 13::US10323020, Example 14::[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl][2-(2,6-dimethylmorpholin-4-yl)pyrimidin-5-yl]methanone (Cis Isomer)	Alpha-2C adrenergic receptor			 47.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398519&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191005	405258570							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796257	CC1CN(CC(C)O1)c1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccccc2C1	InChI=1S/C25H33N5O2/c1-18-15-30(16-19(2)32-18)25-26-13-22(14-27-25)24(31)28-11-8-23(9-12-28)29-10-7-20-5-3-4-6-21(20)17-29/h3-6,13-14,18-19,23H,7-12,15-17H2,1-2H3	BMYFKCKNBYKSDB-UHFFFAOYSA-N	398519	US10323020, Example 13::US10323020, Example 14::[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl][2-(2,6-dimethylmorpholin-4-yl)pyrimidin-5-yl]methanone (Cis Isomer)	Alpha-2C adrenergic receptor			 24.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398519&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191005	405258570							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
796258	CC1(C)CN(CCO1)c1ncc(cn1)C(=O)N1CCC(CC1)N1CCc2ccccc2C1	InChI=1S/C25H33N5O2/c1-25(2)18-30(13-14-32-25)24-26-15-21(16-27-24)23(31)28-11-8-22(9-12-28)29-10-7-19-5-3-4-6-20(19)17-29/h3-6,15-16,22H,7-14,17-18H2,1-2H3	IBSICRNAULLOEM-UHFFFAOYSA-N	398521	US10323020, Example 15::[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidin-1-yl][2-(2,2-dimethylmorpholin-4-yl)pyrimidin-5-yl]methanone	Alpha-2C adrenergic receptor			 68.0							US Patent		10.7270/Q2PN9803		aid1799206	US10323020	Becker-Pelster, EM; Buchgraber, P; Buchmuller, A; Engel, K; Geiss, V; Goller, A; Himmel, H; Kast, R; Knorr, A; Lang, D; Redlich, G; Schmeck, C; Tinel, H; Wunder, F	Bayer Pharma Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398521	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398521&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118191008	405258571							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51100198	O=C(OCc1ccccc1)N1Cc2ccc(cc2C1)N1CCN(CC1)C1CCCC1	InChI=1S/C25H31N3O2/c29-25(30-19-20-6-2-1-3-7-20)28-17-21-10-11-24(16-22(21)18-28)27-14-12-26(13-15-27)23-8-4-5-9-23/h1-3,6-7,10-11,16,23H,4-5,8-9,12-15,17-19H2	FUWNTUBEOVLTGS-UHFFFAOYSA-N	50370518	CHEMBL4176474::US10954217, Example 00229	Alpha-2C adrenergic receptor		 1640								ChEMBL	10.1016/j.ejmech.2018.02.024	10.7270/Q28918FQ	29656199			Linkens, K; Schmidt, HR; Sahn, JJ; Kruse, AC; Martin, SF	University of Texas at Austin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370518&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132060746	160849620						ZINC13584016	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51100221	COc1cccc(c1)-c1ccc2CN(Cc3ccccc3)Cc2c1	InChI=1S/C22H21NO/c1-24-22-9-5-8-18(13-22)19-10-11-20-15-23(16-21(20)12-19)14-17-6-3-2-4-7-17/h2-13H,14-16H2,1H3	LGSGJWDXMWVXEB-UHFFFAOYSA-N	50370603	CHEMBL4167315::US10954217, Example 00225	Alpha-2C adrenergic receptor		 2879								ChEMBL	10.1016/j.ejmech.2018.02.024	10.7270/Q28918FQ	29656199			Linkens, K; Schmidt, HR; Sahn, JJ; Kruse, AC; Martin, SF	University of Texas at Austin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370603&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132060720	160849705						ZINC64539249	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51100288	C(N1Cc2ccc(cc2C1)N1CCOCC1)c1ccccc1	InChI=1S/C19H22N2O/c1-2-4-16(5-3-1)13-20-14-17-6-7-19(12-18(17)15-20)21-8-10-22-11-9-21/h1-7,12H,8-11,13-15H2	LWZFMJZOOLLWCB-UHFFFAOYSA-N	50370662	CHEMBL4161503::US10954217, Example 00224	Alpha-2C adrenergic receptor		 2466								ChEMBL	10.1016/j.ejmech.2018.02.024	10.7270/Q28918FQ	29656199			Linkens, K; Schmidt, HR; Sahn, JJ; Kruse, AC; Martin, SF	University of Texas at Austin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370662&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132060733	160849764	65324					ZINC73138787	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51100289	CN1CCN(CC1)c1ccc2CN(Cc2c1)C(=O)OCc1ccccc1	InChI=1S/C21H25N3O2/c1-22-9-11-23(12-10-22)20-8-7-18-14-24(15-19(18)13-20)21(25)26-16-17-5-3-2-4-6-17/h2-8,13H,9-12,14-16H2,1H3	UETLZTFBKJSNHG-UHFFFAOYSA-N	50370517	CHEMBL4163428::US10954217, Example 00227	Alpha-2C adrenergic receptor		 254								ChEMBL	10.1016/j.ejmech.2018.02.024	10.7270/Q28918FQ	29656199			Linkens, K; Schmidt, HR; Sahn, JJ; Kruse, AC; Martin, SF	University of Texas at Austin	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370517&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132060743	160849619						ZINC13584019	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51136001	OC1(CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1ccc(Cl)c(c1)C(F)(F)F	InChI=1S/C28H27ClF5NO/c29-26-12-7-21(18-25(26)28(32,33)34)27(36)13-16-35(17-14-27)15-1-2-24(19-3-8-22(30)9-4-19)20-5-10-23(31)11-6-20/h3-12,18,24,36H,1-2,13-17H2	MDLAAYDRRZXJIF-UHFFFAOYSA-N	50026066	1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol::1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-4-(4-chloro-3-trifluoromethyl-phenyl)-piperidin-4-ol::CHEMBL47050::PENFLURIDOL1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-4-(4-chloro-3-trifluoromethyl-phenyl)-piperidin-4-ol::Penfluridol	Alpha-2C adrenergic receptor		 445								ChEMBL	10.1016/j.bmcl.2018.10.036	10.7270/Q280558N	30389290			Ashraf-Uz-Zaman, M; Sajib, MS; Cucullo, L; Mikelis, CM; German, NA	Texas Tech University Health Sciences Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026066	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026066&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			33630	103935800		CHEMBL47050				ZINC04217252	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162422	CC(Oc1ccccc1-c1cccnc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	AFWQDDUMQAQVSC-UHFFFAOYSA-N	50002905	CHEMBL373535	Alpha-2C adrenergic receptor					 50					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002905&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11265631	242056301		CHEMBL373535					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162425	CC(Oc1ccccc1-c1cccc(F)c1)C1=NCCN1	InChI=1S/C17H17FN2O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10H2,1H3,(H,19,20)	OOYTZYZXCMCMSZ-UHFFFAOYSA-N	50002903	CHEMBL223836	Alpha-2C adrenergic receptor					 60					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002903&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11211035	242056299		CHEMBL223836					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162427	CC(Oc1ccccc1-c1cccc(C)c1)C1=NCCN1	InChI=1S/C18H20N2O/c1-13-6-5-7-15(12-13)16-8-3-4-9-17(16)21-14(2)18-19-10-11-20-18/h3-9,12,14H,10-11H2,1-2H3,(H,19,20)	OITKDPXYSUWTOJ-UHFFFAOYSA-N	50476173	CHEMBL222973	Alpha-2C adrenergic receptor					 1585					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476173&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11277479	433943438							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162433	CC(Oc1ccccc1-c1ccc(C)cc1)C1=NCCN1	InChI=1S/C18H20N2O/c1-13-7-9-15(10-8-13)16-5-3-4-6-17(16)21-14(2)18-19-11-12-20-18/h3-10,14H,11-12H2,1-2H3,(H,19,20)	FVORBSYXXHDBGZ-UHFFFAOYSA-N	50476175	CHEMBL426900	Alpha-2C adrenergic receptor		 251								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476175&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11173544	433943440							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162434	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2C adrenergic receptor		 200								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162436	CC(Oc1ccccc1-c1ccccc1)C1=NCCS1	InChI=1S/C17H17NOS/c1-13(17-18-11-12-20-17)19-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3	LTDPDISPKAJTKJ-UHFFFAOYSA-N	50476176	CHEMBL222592	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476176&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11278634	433943441							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162437	CC(Oc1ccccc1-c1ccc(O)cc1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-10-11-19-17)21-16-5-3-2-4-15(16)13-6-8-14(20)9-7-13/h2-9,12,20H,10-11H2,1H3,(H,18,19)	LFMHROBTZOFVNB-UHFFFAOYSA-N	50476174	CHEMBL222798	Alpha-2C adrenergic receptor		 331								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476174	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476174&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11186227	433943439							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162438	CC(Oc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2O/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	OGOLMGZJNRNULQ-UHFFFAOYSA-N	50412250	CHEMBL128168	Alpha-2C adrenergic receptor					 58					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412250&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44352207	163361274		CHEMBL128168				ZINC13471587	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162444	CC(Oc1ccccc1-c1cccs1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-8-9-17-15)18-13-6-3-2-5-12(13)14-7-4-10-19-14/h2-7,10-11H,8-9H2,1H3,(H,16,17)	LJLYHROZJUTILK-UHFFFAOYSA-N	50476178	CHEMBL223829	Alpha-2C adrenergic receptor					 59					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476178&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11360447	433943443							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162449	CC(Oc1ccccc1-c1ccccn1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-10-11-19-16)20-15-8-3-2-6-13(15)14-7-4-5-9-17-14/h2-9,12H,10-11H2,1H3,(H,18,19)	WRRWKIRSGSSXLV-UHFFFAOYSA-N	50476179	CHEMBL221989	Alpha-2C adrenergic receptor		 1259								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476179&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11380132	433943444							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162454	CC(Oc1ccccc1-c1cccs1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-8-9-17-15)18-13-6-3-2-5-12(13)14-7-4-10-19-14/h2-7,10-11H,8-9H2,1H3,(H,16,17)	LJLYHROZJUTILK-UHFFFAOYSA-N	50476178	CHEMBL223829	Alpha-2C adrenergic receptor		 72								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476178&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11360447	433943443							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162455	CC(Oc1ccccc1-c1cccnc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	AFWQDDUMQAQVSC-UHFFFAOYSA-N	50002905	CHEMBL373535	Alpha-2C adrenergic receptor					 40					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002905&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11265631	242056301		CHEMBL373535					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162461	CC(Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)	IAIZHDGEGFGNMO-UHFFFAOYSA-N	50417347	CHEMBL385310	Alpha-2C adrenergic receptor					 93					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417347&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11371902	163366371		CHEMBL385310				ZINC13585567	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162462	CC(Oc1ccccc1-c1cccc(C)c1)C1=NCCN1	InChI=1S/C18H20N2O/c1-13-6-5-7-15(12-13)16-8-3-4-9-17(16)21-14(2)18-19-10-11-20-18/h3-9,12,14H,10-11H2,1-2H3,(H,19,20)	OITKDPXYSUWTOJ-UHFFFAOYSA-N	50476173	CHEMBL222973	Alpha-2C adrenergic receptor		 245								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476173&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11277479	433943438							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162464	CC(Oc1ccccc1-c1ccccc1[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-10-11-19-17)23-16-9-5-3-7-14(16)13-6-2-4-8-15(13)20(21)22/h2-9,12H,10-11H2,1H3,(H,18,19)	JACPZVPJACONPS-UHFFFAOYSA-N	50476177	CHEMBL222138	Alpha-2C adrenergic receptor		 1230								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476177	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476177&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11221758	433943442							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162465	CC(Oc1ccccc1-c1ccccc1O)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-10-11-19-17)21-16-9-5-3-7-14(16)13-6-2-4-8-15(13)20/h2-9,12,20H,10-11H2,1H3,(H,18,19)	ACFBDYFNLOKRTR-UHFFFAOYSA-N	50476180	CHEMBL373830	Alpha-2C adrenergic receptor		 1622								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476180	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476180&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11199581	433943445							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162471	CC(Oc1ccccc1-c1ccsc1)C1=NCCN1	InChI=1S/C15H16N2OS/c1-11(15-16-7-8-17-15)18-14-5-3-2-4-13(14)12-6-9-19-10-12/h2-6,9-11H,7-8H2,1H3,(H,16,17)	IAIZHDGEGFGNMO-UHFFFAOYSA-N	50417347	CHEMBL385310	Alpha-2C adrenergic receptor		 132								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417347&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11371902	163366371		CHEMBL385310				ZINC13585567	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162473	C1CN=C(N1)C1OC1c1ccccc1-c1ccccc1	InChI=1S/C17H16N2O/c1-2-6-12(7-3-1)13-8-4-5-9-14(13)15-16(20-15)17-18-10-11-19-17/h1-9,15-16H,10-11H2,(H,18,19)	BTPMSDTWDTXFNP-UHFFFAOYSA-N	50476186	CHEMBL222933	Alpha-2C adrenergic receptor					 2692					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476186&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44421258	433943451					C00722		1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162475	CC(Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)	NMSAVNXFCXMJJY-UHFFFAOYSA-N	50002904	CHEMBL222928	Alpha-2C adrenergic receptor					 158					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002904	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002904&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11361608	242056300		CHEMBL222928					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162476	CC(Oc1ccccc1-c1cccc(N)c1)C1=NCCN1	InChI=1S/C17H19N3O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10,18H2,1H3,(H,19,20)	YVSAGYHRJDVYHG-UHFFFAOYSA-N	50476185	CHEMBL222371	Alpha-2C adrenergic receptor					 501					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476185&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11173568	433943450							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162479	CC(Nc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H19N3/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13,20H,11-12H2,1H3,(H,18,19)	QPAIAAWBFFTOPZ-UHFFFAOYSA-N	50473619	CHEMBL130884	Alpha-2C adrenergic receptor					 93					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473619&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140033	433940884							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162480	CC(Oc1ccccc1-c1ccc(C)cc1)C1=NCCN1	InChI=1S/C18H20N2O/c1-13-7-9-15(10-8-13)16-5-3-4-6-17(16)21-14(2)18-19-11-12-20-18/h3-10,14H,11-12H2,1-2H3,(H,19,20)	FVORBSYXXHDBGZ-UHFFFAOYSA-N	50476175	CHEMBL426900	Alpha-2C adrenergic receptor					 832					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476175&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11173544	433943440							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162486	NC[C@H](O)c1ccc(O)c(O)c1	InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1	SFLSHLFXELFNJZ-QMMMGPOBSA-N	50029051	(-)-arterenol::(-)-noradrenaline::(-)-norepinephrine::(R)-(-)-norepinephrine::(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol::(R)-noradrenaline::(R)-norepinephrine::4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol::CHEMBL1437::NOREPINEPHRINE	Alpha-2C adrenergic receptor					 794					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029051&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	LNR	3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH	439260	103938165	18357	CHEMBL1437	DB00368	505	C00547	ZINC00057624	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162488	CC(Oc1ccccc1-c1ccccc1C)C1=NCCN1	InChI=1S/C18H20N2O/c1-13-7-3-4-8-15(13)16-9-5-6-10-17(16)21-14(2)18-19-11-12-20-18/h3-10,14H,11-12H2,1-2H3,(H,19,20)	PJHALOKEQHBBKK-UHFFFAOYSA-N	50476188	CHEMBL223830	Alpha-2C adrenergic receptor					 363					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476188&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11300487	433943453							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162491	CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)	XGMNRALXOWECNG-UHFFFAOYSA-N	50417350	CHEMBL374584	Alpha-2C adrenergic receptor		 18								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417350&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11346584	163366374		CHEMBL374584				ZINC13585584	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162492	CC(Oc1ccccc1-c1cccnc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-9-10-19-16)20-15-7-3-2-6-14(15)13-5-4-8-17-11-13/h2-8,11-12H,9-10H2,1H3,(H,18,19)	AFWQDDUMQAQVSC-UHFFFAOYSA-N	50002905	CHEMBL373535	Alpha-2C adrenergic receptor		 65								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002905&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11265631	242056301		CHEMBL373535					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162493	CC(Oc1ccccc1-c1ccccc1)C1=NCCC1	InChI=1S/C18H19NO/c1-14(17-11-7-13-19-17)20-18-12-6-5-10-16(18)15-8-3-2-4-9-15/h2-6,8-10,12,14H,7,11,13H2,1H3	XTQYZOCQEJTIQI-UHFFFAOYSA-N	50476184	CHEMBL222593	Alpha-2C adrenergic receptor		 5888								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476184&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11473729	433943449							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162495	CC(Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)	NMSAVNXFCXMJJY-UHFFFAOYSA-N	50002904	CHEMBL222928	Alpha-2C adrenergic receptor					 100					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002904	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002904&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11361608	242056300		CHEMBL222928					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162501	CC(Oc1ccccc1-c1ccccc1)C1=NCCO1	InChI=1S/C17H17NO2/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3	LMLZJQGDSZOQMG-UHFFFAOYSA-N	50476172	CHEMBL222591	Alpha-2C adrenergic receptor		 5888								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476172&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11448533	433943437							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162503	CC(Nc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H19N3/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13,20H,11-12H2,1H3,(H,18,19)	QPAIAAWBFFTOPZ-UHFFFAOYSA-N	50473619	CHEMBL130884	Alpha-2C adrenergic receptor		 708								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473619&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140033	433940884							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162504	CC(Oc1ccccc1-c1ccncc1)C1=NCCN1	InChI=1S/C16H17N3O/c1-12(16-18-10-11-19-16)20-15-5-3-2-4-14(15)13-6-8-17-9-7-13/h2-9,12H,10-11H2,1H3,(H,18,19)	DPCJPADNVXIGHH-UHFFFAOYSA-N	50476181	CHEMBL442045	Alpha-2C adrenergic receptor		 1445								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476181&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11380133	433943446							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162506	CC(Oc1ccccc1-c1cccc(c1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)	NMSAVNXFCXMJJY-UHFFFAOYSA-N	50002904	CHEMBL222928	Alpha-2C adrenergic receptor		 234								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002904	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002904&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11361608	242056300		CHEMBL222928					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162510	Cl.C1CN=C(N1)C1OC1c1ccccc1-c1ccccc1	InChI=1S/C17H16N2O.ClH/c1-2-6-12(7-3-1)13-8-4-5-9-14(13)15-16(20-15)17-18-10-11-19-17;/h1-9,15-16H,10-11H2,(H,18,19);1H	KSQSIGJRCSNCDY-UHFFFAOYSA-N	50476183	CHEMBL1204386	Alpha-2C adrenergic receptor		 4266								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476183&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			52942940	433943448							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162513	CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1	InChI=1S/C17H18N2O2/c1-12(17-18-9-10-19-17)21-16-8-3-2-7-15(16)13-5-4-6-14(20)11-13/h2-8,11-12,20H,9-10H2,1H3,(H,18,19)	XGMNRALXOWECNG-UHFFFAOYSA-N	50417350	CHEMBL374584	Alpha-2C adrenergic receptor					 47					ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417350&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11346584	163366374		CHEMBL374584				ZINC13585584	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162514	CC(Oc1ccccc1-c1ccc(cc1)[N+]([O-])=O)C1=NCCN1	InChI=1S/C17H17N3O3/c1-12(17-18-10-11-19-17)23-16-5-3-2-4-15(16)13-6-8-14(9-7-13)20(21)22/h2-9,12H,10-11H2,1H3,(H,18,19)	ZMDCNVSZNFXVKI-UHFFFAOYSA-N	50476187	CHEMBL221523	Alpha-2C adrenergic receptor		 302								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476187&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11246610	433943452							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162515	C1CN=C(N1)C1OC1c1ccccc1-c1ccccc1	InChI=1S/C17H16N2O/c1-2-6-12(7-3-1)13-8-4-5-9-14(13)15-16(20-15)17-18-10-11-19-17/h1-9,15-16H,10-11H2,(H,18,19)	BTPMSDTWDTXFNP-UHFFFAOYSA-N	50476186	CHEMBL222933	Alpha-2C adrenergic receptor		 6457								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476186&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44421258	433943451					C00722		1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162519	CC(Oc1ccccc1-c1cccc(F)c1)C1=NCCN1	InChI=1S/C17H17FN2O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10H2,1H3,(H,19,20)	OOYTZYZXCMCMSZ-UHFFFAOYSA-N	50002903	CHEMBL223836	Alpha-2C adrenergic receptor		 17								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002903&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11211035	242056299		CHEMBL223836					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162521	CC(Sc1ccccc1-c1ccccc1)C1=NCCN1	InChI=1S/C17H18N2S/c1-13(17-18-11-12-19-17)20-16-10-6-5-9-15(16)14-7-3-2-4-8-14/h2-10,13H,11-12H2,1H3,(H,18,19)	FYBWLLAUJOWVGO-UHFFFAOYSA-N	50476182	CHEMBL374954	Alpha-2C adrenergic receptor		 708								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476182&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11199593	433943447							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162522	CC(Oc1ccccc1-c1cccc(N)c1)C1=NCCN1	InChI=1S/C17H19N3O/c1-12(17-19-9-10-20-17)21-16-8-3-2-7-15(16)13-5-4-6-14(18)11-13/h2-8,11-12H,9-10,18H2,1H3,(H,19,20)	YVSAGYHRJDVYHG-UHFFFAOYSA-N	50476185	CHEMBL222371	Alpha-2C adrenergic receptor		 309								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476185&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11173568	433943450							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51162523	CC(Oc1ccccc1-c1ccccc1C)C1=NCCN1	InChI=1S/C18H20N2O/c1-13-7-3-4-8-15(13)16-9-5-6-10-17(16)21-14(2)18-19-11-12-20-18/h3-10,14H,11-12H2,1-2H3,(H,19,20)	PJHALOKEQHBBKK-UHFFFAOYSA-N	50476188	CHEMBL223830	Alpha-2C adrenergic receptor		 234								ChEMBL	10.1021/jm0408215	10.7270/Q2B27Z13	15566287			Gentili, F; Ghelfi, F; Giannella, M; Piergentili, A; Pigini, M; Quaglia, W; Vesprini, C; Crassous, PA; Paris, H; Carrieri, A	Universit&#163; degli Studi di Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476188&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11300487	433943453							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154660	CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1	InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	IPQYPIRIGUBUAF-MMVSWEMESA-N	50473224	CHEMBL296660	Alpha-2C adrenergic receptor					 21					ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473224	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473224&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292232	433940489							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154661	C1CN=C(N[C@H]2CCCC[C@@H]2c2ccccc2)O1	InChI=1S/C15H20N2O/c1-2-6-12(7-3-1)13-8-4-5-9-14(13)17-15-16-10-11-18-15/h1-3,6-7,13-14H,4-5,8-11H2,(H,16,17)/t13-,14+/m1/s1	NATLAODAVOGBDD-KGLIPLIRSA-N	50473225	CHEMBL297228	Alpha-2C adrenergic receptor		 52								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473225	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473225&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292381	433940490							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154663	C(C[C@H]1CCCC[C@@H]1NC1=NCCO1)Cc1ccccc1	InChI=1S/C18H26N2O/c1-2-7-15(8-3-1)9-6-11-16-10-4-5-12-17(16)20-18-19-13-14-21-18/h1-3,7-8,16-17H,4-6,9-14H2,(H,19,20)/t16-,17+/m1/s1	UDQDKOIZHDPWGR-SJORKVTESA-N	50473227	CHEMBL50720	Alpha-2C adrenergic receptor		 32								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473227	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473227&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10266032	433940492							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154664	CCC[C@H]1CCCC[C@@H]1NC1=NCCO1	InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11-/m0/s1	WDSZUSABLKNHCZ-QWRGUYRKSA-N	50473228	AGN-190837::CHEMBL297752	Alpha-2C adrenergic receptor		 25								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473228	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473228&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9815707	433940493							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154666	C([C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)c1ccccc1	InChI=1S/C17H22N2O/c1-2-4-12(5-3-1)10-15-13-6-7-14(11-13)16(15)19-17-18-8-9-20-17/h1-5,13-16H,6-11H2,(H,18,19)/t13?,14?,15-,16+/m0/s1	NUMRIDYCRYHYHT-SSHXOBKSSA-N	50473229	CHEMBL295186	Alpha-2C adrenergic receptor					 14					ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473229&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292385	433940494							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154668	CCC[C@H]1CCCC[C@@H]1NC1=NCCO1	InChI=1S/C12H22N2O/c1-2-5-10-6-3-4-7-11(10)14-12-13-8-9-15-12/h10-11H,2-9H2,1H3,(H,13,14)/t10-,11-/m0/s1	WDSZUSABLKNHCZ-QWRGUYRKSA-N	50473228	AGN-190837::CHEMBL297752	Alpha-2C adrenergic receptor					 4.1					ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473228	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473228&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9815707	433940493							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154677	C([C@H]1CCCC[C@@H]1NC1=NCCO1)c1ccccc1	InChI=1S/C16H22N2O/c1-2-6-13(7-3-1)12-14-8-4-5-9-15(14)18-16-17-10-11-19-16/h1-3,6-7,14-15H,4-5,8-12H2,(H,17,18)/t14-,15+/m1/s1	YEPGXJIOCYXZAI-CABCVRRESA-N	50473232	CHEMBL50719	Alpha-2C adrenergic receptor		 66								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473232&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10848826	433940497							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154678	CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1	InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	IPQYPIRIGUBUAF-MMVSWEMESA-N	50473224	CHEMBL296660	Alpha-2C adrenergic receptor		 123								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473224	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473224&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292232	433940489							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154680	C(C[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)Cc1ccccc1	InChI=1S/C19H26N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-3,5-6,15-18H,4,7-13H2,(H,20,21)/t15?,16?,17-,18+/m0/s1	PIAONGWBRPZERV-ZGUYJTEBSA-N	50473231	CHEMBL48341	Alpha-2C adrenergic receptor		 123								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473231	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473231&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9971924	433940496							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154681	C(\C=C\c1ccccc1)[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1	InChI=1S/C19H24N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-7,15-18H,8-13H2,(H,20,21)/b7-4+/t15?,16?,17-,18+/m0/s1	RCLSMBSYDRCUSB-CEBMEMTBSA-N	50473226	CHEMBL297827	Alpha-2C adrenergic receptor		 85								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473226	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473226&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292386	433940491							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154688	C([C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)c1ccccc1	InChI=1S/C17H22N2O/c1-2-4-12(5-3-1)10-15-13-6-7-14(11-13)16(15)19-17-18-8-9-20-17/h1-5,13-16H,6-11H2,(H,18,19)/t13?,14?,15-,16+/m0/s1	NUMRIDYCRYHYHT-SSHXOBKSSA-N	50473229	CHEMBL295186	Alpha-2C adrenergic receptor		 79								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473229&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292385	433940494							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154690	C(C[C@H]1CCCC[C@@H]1NC1=NCCO1)Cc1ccccc1	InChI=1S/C18H26N2O/c1-2-7-15(8-3-1)9-6-11-16-10-4-5-12-17(16)20-18-19-13-14-21-18/h1-3,7-8,16-17H,4-6,9-14H2,(H,19,20)/t16-,17+/m1/s1	UDQDKOIZHDPWGR-SJORKVTESA-N	50473227	CHEMBL50720	Alpha-2C adrenergic receptor					 27					ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473227	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473227&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10266032	433940492							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154691	C(\C=C\c1ccccc1)[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1	InChI=1S/C19H24N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-7,15-18H,8-13H2,(H,20,21)/b7-4+/t15?,16?,17-,18+/m0/s1	RCLSMBSYDRCUSB-CEBMEMTBSA-N	50473226	CHEMBL297827	Alpha-2C adrenergic receptor					 2.0					ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473226	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473226&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44292386	433940491							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154692	C(Cc1ccccc1)[C@H]1CCCC[C@@H]1NC1=NCCO1	InChI=1S/C17H24N2O/c1-2-6-14(7-3-1)10-11-15-8-4-5-9-16(15)19-17-18-12-13-20-17/h1-3,6-7,15-16H,4-5,8-13H2,(H,18,19)/t15-,16+/m1/s1	MGQIWQQQIZXANT-CVEARBPZSA-N	50473230	CHEMBL47313	Alpha-2C adrenergic receptor		 11								ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473230	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473230&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10707358	433940495							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51154698	C(C[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1)Cc1ccccc1	InChI=1S/C19H26N2O/c1-2-5-14(6-3-1)7-4-8-17-15-9-10-16(13-15)18(17)21-19-20-11-12-22-19/h1-3,5-6,15-18H,4,7-13H2,(H,20,21)/t15?,16?,17-,18+/m0/s1	PIAONGWBRPZERV-ZGUYJTEBSA-N	50473231	CHEMBL48341	Alpha-2C adrenergic receptor					 60					ChEMBL	10.1021/jm9905256	10.7270/Q2D221C4	10794687			Wong, WC; Sun, W; Cui, W; Chen, Y; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C	Lundbeck Research USA, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473231	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473231&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9971924	433940496							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155831	Cl.CC(C)Sc1ccccc1NCC1=NCCN1	InChI=1S/C13H19N3S/c1-10(2)17-12-6-4-3-5-11(12)16-9-13-14-7-8-15-13/h3-6,10,16H,7-9H2,1-2H3,(H,14,15)	RREJZKOLYMUBNO-UHFFFAOYSA-N	50473663	CHEMBL553276	Alpha-2C adrenergic receptor		 166								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473663&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45260704	433940928							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155836	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C	InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)	WYWIFABBXFUGLM-UHFFFAOYSA-N	30712	6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259	Alpha-2C adrenergic receptor		 59								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	J5C	7EJK	4636	252614969			DB00935		C07363	ZINC00057435	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155849	CS(=O)(=O)c1cccc(F)c1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)9-4-2-3-8(12)11(9)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	FAINGUBYHMRNKU-UHFFFAOYSA-N	50473675	CHEMBL74114	Alpha-2C adrenergic receptor					 447					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473675&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11058166	433940940							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155854	CS(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3O2S/c1-17(15,16)10-5-3-2-4-9(10)14-8-11-12-6-7-13-11/h2-5,14H,6-8H2,1H3,(H,12,13)	MCTRZCCYVQDHLM-UHFFFAOYSA-N	50218593	CHEMBL117094	Alpha-2C adrenergic receptor					 3162					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218593&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9816461	377007553		CHEMBL117094					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155855	CSc1c(F)cccc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-11-8(12)3-2-4-9(11)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	QJUBRJKAGWBYDR-UHFFFAOYSA-N	50473669	CHEMBL70692	Alpha-2C adrenergic receptor					 16					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473669&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140345	433940934							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155862	CS(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3O2S/c1-17(15,16)10-5-3-2-4-9(10)14-8-11-12-6-7-13-11/h2-5,14H,6-8H2,1H3,(H,12,13)	MCTRZCCYVQDHLM-UHFFFAOYSA-N	50218593	CHEMBL117094	Alpha-2C adrenergic receptor		<5012								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218593&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9816461	377007553		CHEMBL117094					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155866	CCS(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C12H17N3O2S/c1-2-18(16,17)11-6-4-3-5-10(11)15-9-12-13-7-8-14-12/h3-6,15H,2,7-9H2,1H3,(H,13,14)	ZZCOHDYKTIEHEF-UHFFFAOYSA-N	50473668	CHEMBL70973	Alpha-2C adrenergic receptor					 5012					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473668&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10221004	433940933							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155878	CSc1cc(F)ccc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	XBBHVMXFPPVGMX-UHFFFAOYSA-N	50473678	CHEMBL306792	Alpha-2C adrenergic receptor		 219								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473678&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11097789	433940943							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155884	CS(=O)(=O)c1c(F)cccc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)11-8(12)3-2-4-9(11)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	FFVMPJRYEFKURT-UHFFFAOYSA-N	50473667	CHEMBL419448	Alpha-2C adrenergic receptor		 257								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473667&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11090351	433940932							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155888	CSc1ccc(F)cc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	BCCMUPQZPVRDCD-UHFFFAOYSA-N	50473672	CHEMBL72768	Alpha-2C adrenergic receptor					 5.6					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473672&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140347	433940937							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155892	CS(=O)(=O)c1cc(Cl)ccc1NCC1=NCCN1	InChI=1S/C11H14ClN3O2S/c1-18(16,17)10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	RNPCNKHTEISXAL-UHFFFAOYSA-N	50473676	CHEMBL70563	Alpha-2C adrenergic receptor		 3981								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473676&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10916464	433940941							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155896	Cl.CCCS(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C13H19N3O2S/c1-2-9-19(17,18)12-6-4-3-5-11(12)16-10-13-14-7-8-15-13/h3-6,16H,2,7-10H2,1H3,(H,14,15)	DURATMICCIEKQS-UHFFFAOYSA-N	50473679	CHEMBL554416	Alpha-2C adrenergic receptor		 2630								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473679&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			22493245	433940944							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155900	CSc1ccc(cc1NCC1=NCCN1)C(F)(F)F	InChI=1S/C12H14F3N3S/c1-19-10-3-2-8(12(13,14)15)6-9(10)18-7-11-16-4-5-17-11/h2-3,6,18H,4-5,7H2,1H3,(H,16,17)	GBSLCSDIFSTSOZ-UHFFFAOYSA-N	50473683	CHEMBL72724	Alpha-2C adrenergic receptor					 7.9					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473683&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11034737	433940948							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155902	CSc1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3S/c1-15-10-5-3-2-4-9(10)14-8-11-12-6-7-13-11/h2-5,14H,6-8H2,1H3,(H,12,13)	YGIWTZGEYHABOR-UHFFFAOYSA-N	50421580	CHEMBL117248	Alpha-2C adrenergic receptor		 145								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421580&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11108001	164150455		CHEMBL117248				ZINC13473754	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155903	Cl.C[S+]([O-])c1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3OS.ClH/c1-16(15)10-5-3-2-4-9(10)14-8-11-12-6-7-13-11;/h2-5,14H,6-8H2,1H3,(H,12,13);1H	CLJWUQUYJYUFLN-UHFFFAOYSA-N	50473666	CHEMBL542402	Alpha-2C adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473666&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45260703	433940931							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155904	CSc1ccc(C)cc1NCC1=NCCN1	InChI=1S/C12H17N3S/c1-9-3-4-11(16-2)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	ZVVQFUFKMNLNCB-UHFFFAOYSA-N	50473677	CHEMBL72441	Alpha-2C adrenergic receptor		 200								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473677&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10934575	433940942							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155907	CS(=O)(=O)c1cc(F)ccc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	DLSVKFMVCHCZLY-UHFFFAOYSA-N	50473664	CHEMBL70326	Alpha-2C adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473664&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11079593	433940929							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155933	CS(=O)(=O)c1ccc(cc1NCC1=NCCN1)C(F)(F)F	InChI=1S/C12H14F3N3O2S/c1-21(19,20)10-3-2-8(12(13,14)15)6-9(10)18-7-11-16-4-5-17-11/h2-3,6,18H,4-5,7H2,1H3,(H,16,17)	NEAKCLFZBLSGMR-UHFFFAOYSA-N	50473680	CHEMBL302698	Alpha-2C adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473680&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11059195	433940945							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155936	CS(=O)(=O)Nc1ccc(F)c(c1)[C@@H](O)CN	InChI=1S/C9H13FN2O3S/c1-16(14,15)12-6-2-3-8(10)7(4-6)9(13)5-11/h2-4,9,12-13H,5,11H2,1H3/t9-/m0/s1	XYLJNMCMDOOJRW-VIFPVBQESA-N	50000215	NS-49	Alpha-2C adrenergic receptor					 1995					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000215	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000215&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9838763	242055755							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155940	Cl.CCSc1ccccc1NCC1=NCCN1	InChI=1S/C12H17N3S/c1-2-16-11-6-4-3-5-10(11)15-9-12-13-7-8-14-12/h3-6,15H,2,7-9H2,1H3,(H,13,14)	MZDQVKPPFWIZIL-UHFFFAOYSA-N	50473681	CHEMBL540035	Alpha-2C adrenergic receptor					 28					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473681&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45264638	433940946							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155950	COc1ccc(SC)c(NCC2=NCCN2)c1	InChI=1S/C12H17N3OS/c1-16-9-3-4-11(17-2)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	NMTCRDZBJDXVCH-UHFFFAOYSA-N	50473682	CHEMBL70691	Alpha-2C adrenergic receptor		 603								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473682&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11098175	433940947							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155961	CSc1ccc(Cl)cc1NCC1=NCCN1	InChI=1S/C11H14ClN3S/c1-16-10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	ZHDIISZEXUGDAJ-UHFFFAOYSA-N	50473665	CHEMBL70751	Alpha-2C adrenergic receptor		 170								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473665&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11109088	433940930							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155965	CSc1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3S/c1-15-10-5-3-2-4-9(10)14-8-11-12-6-7-13-11/h2-5,14H,6-8H2,1H3,(H,12,13)	YGIWTZGEYHABOR-UHFFFAOYSA-N	50421580	CHEMBL117248	Alpha-2C adrenergic receptor					 5.6					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421580&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11108001	164150455		CHEMBL117248				ZINC13473754	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155967	CS(=O)(=O)c1cc(F)ccc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	DLSVKFMVCHCZLY-UHFFFAOYSA-N	50473664	CHEMBL70326	Alpha-2C adrenergic receptor		<5012								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473664&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11079593	433940929							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155974	O=S1(=O)CCCc2cccc(NCC3=NCCN3)c12	InChI=1S/C13H17N3O2S/c17-19(18)8-2-4-10-3-1-5-11(13(10)19)16-9-12-14-6-7-15-12/h1,3,5,16H,2,4,6-9H2,(H,14,15)	WAXAHQBOIDNYSY-UHFFFAOYSA-N	50473670	CHEMBL70740	Alpha-2C adrenergic receptor		 2692								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473670&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10923927	433940935							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155975	CS(=O)(=O)c1cc(Cl)ccc1NCC1=NCCN1	InChI=1S/C11H14ClN3O2S/c1-18(16,17)10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	RNPCNKHTEISXAL-UHFFFAOYSA-N	50473676	CHEMBL70563	Alpha-2C adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473676&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10916464	433940941							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155982	Cl.CC(C)Sc1ccccc1NCC1=NCCN1	InChI=1S/C13H19N3S/c1-10(2)17-12-6-4-3-5-11(12)16-9-13-14-7-8-15-13/h3-6,10,16H,7-9H2,1-2H3,(H,14,15)	RREJZKOLYMUBNO-UHFFFAOYSA-N	50473663	CHEMBL553276	Alpha-2C adrenergic receptor					 28					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473663&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45260704	433940928							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155986	CS(=O)(=O)c1ccc(Cl)cc1NCC1=NCCN1	InChI=1S/C11H14ClN3O2S/c1-18(16,17)10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	VFLQPKLTPYIDEK-UHFFFAOYSA-N	50473674	CHEMBL70634	Alpha-2C adrenergic receptor		 4786								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473674&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9947861	433940939							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155990	CC(C)S(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C13H19N3O2S/c1-10(2)19(17,18)12-6-4-3-5-11(12)16-9-13-14-7-8-15-13/h3-6,10,16H,7-9H2,1-2H3,(H,14,15)	XDUYFOWMTMCCEI-UHFFFAOYSA-N	50473673	CHEMBL74071	Alpha-2C adrenergic receptor					<10000					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473673&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11811395	433940938							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51155997	CS(=O)(=O)c1cccc(F)c1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)9-4-2-3-8(12)11(9)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	FAINGUBYHMRNKU-UHFFFAOYSA-N	50473675	CHEMBL74114	Alpha-2C adrenergic receptor		 692								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473675&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11058166	433940940							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156001	Cc1ccc(c(NCC2=NCCN2)c1)S(C)(=O)=O	InChI=1S/C12H17N3O2S/c1-9-3-4-11(18(2,16)17)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	NIILDWZATWLEEZ-UHFFFAOYSA-N	50473671	CHEMBL71479	Alpha-2C adrenergic receptor		<5012								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473671&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10221005	433940936							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156005	CSc1ccc(F)cc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	BCCMUPQZPVRDCD-UHFFFAOYSA-N	50473672	CHEMBL72768	Alpha-2C adrenergic receptor		 115								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473672&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140347	433940937							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156009	CCS(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C12H17N3O2S/c1-2-18(16,17)11-6-4-3-5-10(11)15-9-12-13-7-8-14-12/h3-6,15H,2,7-9H2,1H3,(H,13,14)	ZZCOHDYKTIEHEF-UHFFFAOYSA-N	50473668	CHEMBL70973	Alpha-2C adrenergic receptor		 2512								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473668&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10221004	433940933							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156020	COc1ccc(c(NCC2=NCCN2)c1)S(C)(=O)=O	InChI=1S/C12H17N3O3S/c1-18-9-3-4-11(19(2,16)17)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	WURKOHONKFWQNR-UHFFFAOYSA-N	50218568	CHEMBL71001	Alpha-2C adrenergic receptor		<5012								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218568&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9817256	377007550		CHEMBL71001					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156028	CSc1ccc(Cl)cc1NCC1=NCCN1	InChI=1S/C11H14ClN3S/c1-16-10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	ZHDIISZEXUGDAJ-UHFFFAOYSA-N	50473665	CHEMBL70751	Alpha-2C adrenergic receptor					 2.8					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473665&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11109088	433940930							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156036	CC(C)S(=O)(=O)c1ccccc1NCC1=NCCN1	InChI=1S/C13H19N3O2S/c1-10(2)19(17,18)12-6-4-3-5-11(12)16-9-13-14-7-8-15-13/h3-6,10,16H,7-9H2,1-2H3,(H,14,15)	XDUYFOWMTMCCEI-UHFFFAOYSA-N	50473673	CHEMBL74071	Alpha-2C adrenergic receptor		<5012								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473673&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11811395	433940938							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156046	CSc1c(F)cccc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-11-8(12)3-2-4-9(11)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	QJUBRJKAGWBYDR-UHFFFAOYSA-N	50473669	CHEMBL70692	Alpha-2C adrenergic receptor		 219								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473669&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11140345	433940934							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156055	CSc1ccc(C)cc1NCC1=NCCN1	InChI=1S/C12H17N3S/c1-9-3-4-11(16-2)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	ZVVQFUFKMNLNCB-UHFFFAOYSA-N	50473677	CHEMBL72441	Alpha-2C adrenergic receptor					 8.9					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473677&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10934575	433940942							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156060	CS(=O)(=O)c1ccc(F)cc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	YYHDOUOUAFMQDK-UHFFFAOYSA-N	50473684	CHEMBL74467	Alpha-2C adrenergic receptor		<5012								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473684&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10199335	433940949							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156061	O=S1(=O)CCCc2cccc(NCC3=NCCN3)c12	InChI=1S/C13H17N3O2S/c17-19(18)8-2-4-10-3-1-5-11(13(10)19)16-9-12-14-6-7-15-12/h1,3,5,16H,2,4,6-9H2,(H,14,15)	WAXAHQBOIDNYSY-UHFFFAOYSA-N	50473670	CHEMBL70740	Alpha-2C adrenergic receptor					 6310					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473670&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10923927	433940935							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156068	Cl.CCSc1ccccc1NCC1=NCCN1	InChI=1S/C12H17N3S/c1-2-16-11-6-4-3-5-10(11)15-9-12-13-7-8-14-12/h3-6,15H,2,7-9H2,1H3,(H,13,14)	MZDQVKPPFWIZIL-UHFFFAOYSA-N	50473681	CHEMBL540035	Alpha-2C adrenergic receptor		 269								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473681&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45264638	433940946							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156071	CS(=O)(=O)c1c(F)cccc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)11-8(12)3-2-4-9(11)15-7-10-13-5-6-14-10/h2-4,15H,5-7H2,1H3,(H,13,14)	FFVMPJRYEFKURT-UHFFFAOYSA-N	50473667	CHEMBL419448	Alpha-2C adrenergic receptor					 501					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473667&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11090351	433940932							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156072	CS(=O)(=O)c1ccc(Cl)cc1NCC1=NCCN1	InChI=1S/C11H14ClN3O2S/c1-18(16,17)10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	VFLQPKLTPYIDEK-UHFFFAOYSA-N	50473674	CHEMBL70634	Alpha-2C adrenergic receptor					 794					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473674&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9947861	433940939							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156073	CSc1ccc(cc1NCC1=NCCN1)C(F)(F)F	InChI=1S/C12H14F3N3S/c1-19-10-3-2-8(12(13,14)15)6-9(10)18-7-11-16-4-5-17-11/h2-3,6,18H,4-5,7H2,1H3,(H,16,17)	GBSLCSDIFSTSOZ-UHFFFAOYSA-N	50473683	CHEMBL72724	Alpha-2C adrenergic receptor		 603								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473683&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11034737	433940948							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156085	Cc1ccc(c(NCC2=NCCN2)c1)S(C)(=O)=O	InChI=1S/C12H17N3O2S/c1-9-3-4-11(18(2,16)17)10(7-9)15-8-12-13-5-6-14-12/h3-4,7,15H,5-6,8H2,1-2H3,(H,13,14)	NIILDWZATWLEEZ-UHFFFAOYSA-N	50473671	CHEMBL71479	Alpha-2C adrenergic receptor					 1122					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473671&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10221005	433940936							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156095	CS(=O)(=O)c1ccc(cc1NCC1=NCCN1)C(F)(F)F	InChI=1S/C12H14F3N3O2S/c1-21(19,20)10-3-2-8(12(13,14)15)6-9(10)18-7-11-16-4-5-17-11/h2-3,6,18H,4-5,7H2,1H3,(H,16,17)	NEAKCLFZBLSGMR-UHFFFAOYSA-N	50473680	CHEMBL302698	Alpha-2C adrenergic receptor		<5012								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473680&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11059195	433940945							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156099	Cl.C[S+]([O-])c1ccccc1NCC1=NCCN1	InChI=1S/C11H15N3OS.ClH/c1-16(15)10-5-3-2-4-9(10)14-8-11-12-6-7-13-11;/h2-5,14H,6-8H2,1H3,(H,12,13);1H	CLJWUQUYJYUFLN-UHFFFAOYSA-N	50473666	CHEMBL542402	Alpha-2C adrenergic receptor		<5012								ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473666&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			45260703	433940931							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156102	CSc1cc(F)ccc1NCC1=NCCN1	InChI=1S/C11H14FN3S/c1-16-10-6-8(12)2-3-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	XBBHVMXFPPVGMX-UHFFFAOYSA-N	50473678	CHEMBL306792	Alpha-2C adrenergic receptor					 100					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473678&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11097789	433940943							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51156112	CS(=O)(=O)c1ccc(F)cc1NCC1=NCCN1	InChI=1S/C11H14FN3O2S/c1-18(16,17)10-3-2-8(12)6-9(10)15-7-11-13-4-5-14-11/h2-3,6,15H,4-5,7H2,1H3,(H,13,14)	YYHDOUOUAFMQDK-UHFFFAOYSA-N	50473684	CHEMBL74467	Alpha-2C adrenergic receptor					 1995					ChEMBL	10.1021/jm000542r	10.7270/Q2NG4TCQ	12014961			Hodson, SJ; Bishop, MJ; Speake, JD; Navas, F; Garrison, DT; Bigham, EC; Saussy, DL; Liacos, JA; Irving, PE; Gobel, MJ; Sherman, BW	GlaxoSmithKline Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473684&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10199335	433940949							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51150938	CC1=C(C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C36H39N3O5/c1-24-31(33(32(35(41)42)25(2)38-24)26-14-15-29-30(22-26)44-23-43-29)34(40)37-18-9-19-39-20-16-36(17-21-39,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-15,22,33,38H,9,16-21,23H2,1-2H3,(H,37,40)(H,41,42)	GUTLHNWEBBMLCC-UHFFFAOYSA-N	50471688	CHEMBL313251	Alpha-2C adrenergic receptor		 776								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471688&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10579368	433938953							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51150949	CO\C(O)=C1\C(C(C(=O)NCCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C37H42N4O5/c1-26-32(34(33(27(2)39-26)36(43)46-3)28-16-18-31(19-17-28)41(44)45)35(42)38-22-10-11-23-40-24-20-37(21-25-40,29-12-6-4-7-13-29)30-14-8-5-9-15-30/h4-9,12-19,34,43H,10-11,20-25H2,1-3H3,(H,38,42)/b36-33+	SZTNZABXFFPBMM-PKUSAGTQSA-N	50471686	CHEMBL284470	Alpha-2C adrenergic receptor		 282								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471686&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10793963	433938951							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51150962	COC(=O)C1C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C36H40N4O5/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-15-17-30(18-16-27)40(43)44)34(41)37-21-10-22-39-23-19-36(20-24-39,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,32-33H,10,19-24H2,1-3H3,(H,37,41)	PQRXHDGVJRPPSF-UHFFFAOYSA-N	50366618	CHEMBL448620::SNAP-5089	Alpha-2C adrenergic receptor		 372								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366618&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			54203251	160845720		CHEMBL448620				ZINC28759802	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51150979	CC1=C(C#N)C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N1)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C35H37N5O3/c1-25-31(24-36)33(27-14-16-30(17-15-27)40(42)43)32(26(2)38-25)34(41)37-20-9-21-39-22-18-35(19-23-39,28-10-5-3-6-11-28)29-12-7-4-8-13-29/h3-8,10-17,33,38H,9,18-23H2,1-2H3,(H,37,41)	JAXIKFIDJJLTAT-UHFFFAOYSA-N	50471699	CHEMBL327775	Alpha-2C adrenergic receptor		 479								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471699&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10626982	433938964							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151003	CC1=C(C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N1)c1ccc2OCOc2c1)C(N)=O	InChI=1S/C36H40N4O4/c1-24-31(34(37)41)33(26-14-15-29-30(22-26)44-23-43-29)32(25(2)39-24)35(42)38-18-9-19-40-20-16-36(17-21-40,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-15,22,33,39H,9,16-21,23H2,1-2H3,(H2,37,41)(H,38,42)	MWOOWQMUFWOYRV-UHFFFAOYSA-N	50471691	CHEMBL312871	Alpha-2C adrenergic receptor		 724								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471691&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10651080	433938956							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151012	CNC(=O)C1=C(C)NC(C)=C(C1c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H41N5O4/c1-25-31(34(42)37-3)33(27-15-17-30(18-16-27)41(44)45)32(26(2)39-25)35(43)38-21-10-22-40-23-19-36(20-24-40,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,33,39H,10,19-24H2,1-3H3,(H,37,42)(H,38,43)	YMSCVVXGMWMEMM-UHFFFAOYSA-N	50471703	CHEMBL284103	Alpha-2C adrenergic receptor		 324								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471703&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10841387	433938968							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151013	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(OC)cc1	InChI=1S/C37H43N3O4/c1-26-32(34(28-16-18-31(43-3)19-17-28)33(27(2)39-26)36(42)44-4)35(41)38-22-11-23-40-24-20-37(21-25-40,29-12-7-5-8-13-29)30-14-9-6-10-15-30/h5-10,12-19,34,42H,11,20-25H2,1-4H3,(H,38,41)/b36-33+	VHYJQKUBUIGDCY-PKUSAGTQSA-N	50471701	CHEMBL315538	Alpha-2C adrenergic receptor		 1148								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471701&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10841190	433938966							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151015	COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1	InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)	VCKUSRYTPJJLNI-UHFFFAOYSA-N	50033111	1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine::6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine::CHEMBL611::TERAZOSIN::Terazosine	Alpha-2C adrenergic receptor		 224								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033111&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	TZN	4O3F,4O33	5401	103941452	9445	CHEMBL611	DB01162	7302	C07127	ZINC01271441	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151016	CO\C(O)=C1\C(C(C(=O)N(C)CCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C37H42N4O5/c1-26-32(34(33(27(2)38-26)36(43)46-4)28-16-18-31(19-17-28)41(44)45)35(42)39(3)22-11-23-40-24-20-37(21-25-40,29-12-7-5-8-13-29)30-14-9-6-10-15-30/h5-10,12-19,34,43H,11,20-25H2,1-4H3/b36-33+	AHCOOGMIZVMEKD-PKUSAGTQSA-N	50471702	CHEMBL88448	Alpha-2C adrenergic receptor		 245								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471702&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10603951	433938967							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151026	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)C#N	InChI=1S/C37H40N4O3/c1-26-32(34(29-17-15-28(25-38)16-18-29)33(27(2)40-26)36(43)44-3)35(42)39-21-10-22-41-23-19-37(20-24-41,30-11-6-4-7-12-30)31-13-8-5-9-14-31/h4-9,11-18,34,43H,10,19-24H2,1-3H3,(H,39,42)/b36-33+	OUDWCNZTASZGHL-PKUSAGTQSA-N	50471692	CHEMBL89243	Alpha-2C adrenergic receptor		 871								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471692&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10674896	433938957							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151030	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(Cl)c(Cl)c1	InChI=1S/C36H39Cl2N3O3/c1-24-31(33(26-15-16-29(37)30(38)23-26)32(25(2)40-24)35(43)44-3)34(42)39-19-10-20-41-21-17-36(18-22-41,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23,33,43H,10,17-22H2,1-3H3,(H,39,42)/b35-32+	JZHXLYHEWUWHQL-LVYIWIAJSA-N	50471687	CHEMBL327712	Alpha-2C adrenergic receptor		 158								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471687&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10651654	433938952							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151031	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(C)cc1	InChI=1S/C37H43N3O3/c1-26-16-18-29(19-17-26)34-32(27(2)39-28(3)33(34)36(42)43-4)35(41)38-22-11-23-40-24-20-37(21-25-40,30-12-7-5-8-13-30)31-14-9-6-10-15-31/h5-10,12-19,34,42H,11,20-25H2,1-4H3,(H,38,41)/b36-33+	CACGBSVXIXSELL-PKUSAGTQSA-N	50471696	CHEMBL315914	Alpha-2C adrenergic receptor		 417								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471696&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10627021	433938961							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151032	CC(=O)C1=C(C)NC(C)=C(C1c1ccc2OCOc2c1)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C37H41N3O4/c1-25-33(27(3)41)35(28-15-16-31-32(23-28)44-24-43-31)34(26(2)39-25)36(42)38-19-10-20-40-21-17-37(18-22-40,29-11-6-4-7-12-29)30-13-8-5-9-14-30/h4-9,11-16,23,35,39H,10,17-22,24H2,1-3H3,(H,38,42)	FOGMNVRCPAJQDZ-UHFFFAOYSA-N	50471690	CHEMBL88388	Alpha-2C adrenergic receptor		 407								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471690&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10507651	433938955							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151036	CN(C)C(=O)C1=C(C)NC(C)=C(C1c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C37H43N5O4/c1-26-32(34(28-16-18-31(19-17-28)42(45)46)33(27(2)39-26)36(44)40(3)4)35(43)38-22-11-23-41-24-20-37(21-25-41,29-12-7-5-8-13-29)30-14-9-6-10-15-30/h5-10,12-19,34,39H,11,20-25H2,1-4H3,(H,38,43)	SNLNBLRAKFOCGE-UHFFFAOYSA-N	50471704	CHEMBL315392	Alpha-2C adrenergic receptor		 813								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471704&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10508132	433938969							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151043	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C30H36N4O5/c1-20-26(28(27(21(2)32-20)30(36)39-3)24-10-12-25(13-11-24)34(37)38)29(35)31-16-7-17-33-18-14-23(15-19-33)22-8-5-4-6-9-22/h4-6,8-13,23,28,36H,7,14-19H2,1-3H3,(H,31,35)/b30-27+	KADUIVAIJUZKJS-KDJFERLWSA-N	50471700	CHEMBL91022	Alpha-2C adrenergic receptor		 81								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471700&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9828476	433938965							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151046	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc2ccccc2c1	InChI=1S/C40H43N3O3/c1-28-35(37(36(29(2)42-28)39(45)46-3)32-20-19-30-13-10-11-14-31(30)27-32)38(44)41-23-12-24-43-25-21-40(22-26-43,33-15-6-4-7-16-33)34-17-8-5-9-18-34/h4-11,13-20,27,37,45H,12,21-26H2,1-3H3,(H,41,44)/b39-36+	OBVUZKZJWYCTTA-WQBMDMGNSA-N	50471693	CHEMBL92322	Alpha-2C adrenergic receptor		 631								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471693&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10508016	433938958							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151053	CO\C(O)=C1\C(C(C(=O)NCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(cc1)[N+]([O-])=O	InChI=1S/C35H38N4O5/c1-24-30(32(31(25(2)37-24)34(41)44-3)26-14-16-29(17-15-26)39(42)43)33(40)36-20-23-38-21-18-35(19-22-38,27-10-6-4-7-11-27)28-12-8-5-9-13-28/h4-17,32,41H,18-23H2,1-3H3,(H,36,40)/b34-31+	YQTAOHSPORUWMC-WUVHBKSUSA-N	50471706	CHEMBL91956	Alpha-2C adrenergic receptor		 245								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471706	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471706&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10531532	433938971							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151055	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)c2ccccc2)=C(C)N=C1C)c1ccc(Cl)c(c1)[N+]([O-])=O	InChI=1S/C30H35ClN4O5/c1-19-26(29(36)32-14-7-15-34-16-12-22(13-17-34)21-8-5-4-6-9-21)28(27(20(2)33-19)30(37)40-3)23-10-11-24(31)25(18-23)35(38)39/h4-6,8-11,18,22,28,37H,7,12-17H2,1-3H3,(H,32,36)/b30-27+	XETGFITVYCWVGB-KDJFERLWSA-N	50471684	CHEMBL327931	Alpha-2C adrenergic receptor		 48								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471684&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10769331	433938949							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151063	CC(C)C1=C(C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(N1)C(C)C)c1ccc(cc1)[N+]([O-])=O)C(N)=O	InChI=1S/C39H47N5O4/c1-26(2)35-33(37(40)45)32(28-16-18-31(19-17-28)44(47)48)34(36(42-35)27(3)4)38(46)41-22-11-23-43-24-20-39(21-25-43,29-12-7-5-8-13-29)30-14-9-6-10-15-30/h5-10,12-19,26-27,32,42H,11,20-25H2,1-4H3,(H2,40,45)(H,41,46)	OXDMFICMRHFYME-UHFFFAOYSA-N	50471705	CHEMBL313953	Alpha-2C adrenergic receptor		 427								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471705&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10818003	433938970							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151064	CNC(=O)C1=C(C)NC(C)=C(C1c1ccc2OCOc2c1)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C37H42N4O4/c1-25-32(35(42)38-3)34(27-15-16-30-31(23-27)45-24-44-30)33(26(2)40-25)36(43)39-19-10-20-41-21-17-37(18-22-41,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-16,23,34,40H,10,17-22,24H2,1-3H3,(H,38,42)(H,39,43)	GJSIQLZDGMIVKC-UHFFFAOYSA-N	50471689	CHEMBL88628	Alpha-2C adrenergic receptor		 1023								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471689&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11801828	433938954							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151073	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc2OCOc2c1	InChI=1S/C37H41N3O5/c1-25-32(34(33(26(2)39-25)36(42)43-3)27-15-16-30-31(23-27)45-24-44-30)35(41)38-19-10-20-40-21-17-37(18-22-40,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-16,23,34,42H,10,17-22,24H2,1-3H3,(H,38,41)/b36-33+	WJRKWJSQVYFSFK-PKUSAGTQSA-N	50471697	CHEMBL91415	Alpha-2C adrenergic receptor		 575								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471697&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10531766	433938962							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151076	CC1=NC(C)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C35H39N5O4/c1-24-30(33(36)41)32(26-14-16-29(17-15-26)40(43)44)31(25(2)38-24)34(42)37-20-9-21-39-22-18-35(19-23-39,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-17,30,32H,9,18-23H2,1-2H3,(H2,36,41)(H,37,42)	JWIXQLYEPDLLJM-UHFFFAOYSA-N	50068828	2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL279436	Alpha-2C adrenergic receptor		 165								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068828&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53978088	103963006		CHEMBL279436				ZINC28759508	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151087	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(Cl)cc1	InChI=1S/C36H40ClN3O3/c1-25-31(33(27-15-17-30(37)18-16-27)32(26(2)39-25)35(42)43-3)34(41)38-21-10-22-40-23-19-36(20-24-40,28-11-6-4-7-12-28)29-13-8-5-9-14-29/h4-9,11-18,33,42H,10,19-24H2,1-3H3,(H,38,41)/b35-32+	WFSGQIXIGIQILN-LVYIWIAJSA-N	50471695	CHEMBL314960	Alpha-2C adrenergic receptor		 1000								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471695&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10793665	433938960							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151092	CC(=O)C1=C(C)NC(C)=C(C1c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C36H40N4O4/c1-25-32(27(3)41)34(28-15-17-31(18-16-28)40(43)44)33(26(2)38-25)35(42)37-21-10-22-39-23-19-36(20-24-39,29-11-6-4-7-12-29)30-13-8-5-9-14-30/h4-9,11-18,34,38H,10,19-24H2,1-3H3,(H,37,42)	SCZDZQFTMOOIDO-UHFFFAOYSA-N	50471698	CHEMBL89685	Alpha-2C adrenergic receptor		 372								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471698&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9851486	433938963							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151093	CC1=NC(C)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C35H39N5O4/c1-24-30(33(36)41)32(26-14-16-29(17-15-26)40(43)44)31(25(2)38-24)34(42)37-20-9-21-39-22-18-35(19-23-39,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-17,30,32H,9,18-23H2,1-2H3,(H2,36,41)(H,37,42)	JWIXQLYEPDLLJM-UHFFFAOYSA-N	50068828	2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL279436	Alpha-2C adrenergic receptor		 165								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068828&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53978088	103963006		CHEMBL279436				ZINC28759508	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151094	CC1=NC(C)=C(C(C1C(N)=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NCCCN1CCC(CC1)(c1ccccc1)c1ccccc1	InChI=1S/C35H39N5O4/c1-24-30(33(36)41)32(26-14-16-29(17-15-26)40(43)44)31(25(2)38-24)34(42)37-20-9-21-39-22-18-35(19-23-39,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-17,30,32H,9,18-23H2,1-2H3,(H2,36,41)(H,37,42)	JWIXQLYEPDLLJM-UHFFFAOYSA-N	50068828	2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-amide 5-{[3-(4,4-diphenyl-piperidin-1-yl)-propyl]-amide}::CHEMBL279436	Alpha-2C adrenergic receptor		 166								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068828&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			53978088	103963006		CHEMBL279436				ZINC28759508	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151099	CCC1=C(C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(CC)N1)c1ccc(cc1)[N+]([O-])=O)C(N)=O	InChI=1S/C37H43N5O4/c1-3-30-33(35(38)43)32(26-16-18-29(19-17-26)42(45)46)34(31(4-2)40-30)36(44)39-22-11-23-41-24-20-37(21-25-41,27-12-7-5-8-13-27)28-14-9-6-10-15-28/h5-10,12-19,32,40H,3-4,11,20-25H2,1-2H3,(H2,38,43)(H,39,44)	JEZMYAZTGNMODX-UHFFFAOYSA-N	50471694	CHEMBL91550	Alpha-2C adrenergic receptor		 191								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471694&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			9895326	433938959							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51151106	CO\C(O)=C1\C(C(C(=O)NCCCN2CCC(CC2)(c2ccccc2)c2ccccc2)=C(C)N=C1C)c1ccc(c(OC)c1)[N+]([O-])=O	InChI=1S/C37H42N4O6/c1-25-32(34(33(26(2)39-25)36(43)47-4)27-16-17-30(41(44)45)31(24-27)46-3)35(42)38-20-11-21-40-22-18-37(19-23-40,28-12-7-5-8-13-28)29-14-9-6-10-15-29/h5-10,12-17,24,34,43H,11,18-23H2,1-4H3,(H,38,42)/b36-33+	BTYBILKFYYEYRM-PKUSAGTQSA-N	50471685	CHEMBL313160	Alpha-2C adrenergic receptor		 398								ChEMBL	10.1021/jm980077m	10.7270/Q24170TM	9651170			Wong, WC; Chiu, G; Wetzel, JM; Marzabadi, MR; Nagarathnam, D; Wang, D; Fang, J; Miao, SW; Hong, X; Forray, C; Vaysse, PJ; Branchek, TA; Gluchowski, C; Tang, R; Lepor, H	New York University Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471685&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			10508332	433938950							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51175877	OC(=O)CCCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1	InChI=1S/C24H33N3O4/c28-21(29)9-2-1-5-12-26-14-10-18(11-15-26)17-25-23(30)22-19-7-3-4-8-20(19)27-13-6-16-31-24(22)27/h3-4,7-8,18H,1-2,5-6,9-17H2,(H,25,30)(H,28,29)	ODMLUIATXKBXOW-UHFFFAOYSA-N	50483176	CHEMBL1632174	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2010.10.011	10.7270/Q2FR00GH	21075638			Brudeli, B; Moltzau, LR; Andressen, KW; Krobert, KA; Klaveness, J; Levy, FO	Drug Discovery Laboratory AS	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50483176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50483176&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			50898778	433950441							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51175907	COC(=O)CCCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1	InChI=1S/C25H35N3O4/c1-31-22(29)10-3-2-6-13-27-15-11-19(12-16-27)18-26-24(30)23-20-8-4-5-9-21(20)28-14-7-17-32-25(23)28/h4-5,8-9,19H,2-3,6-7,10-18H2,1H3,(H,26,30)	RNXYMZNGMNWKMC-UHFFFAOYSA-N	50483172	CHEMBL1632158	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1016/j.bmc.2010.10.011	10.7270/Q2FR00GH	21075638			Brudeli, B; Moltzau, LR; Andressen, KW; Krobert, KA; Klaveness, J; Levy, FO	Drug Discovery Laboratory AS	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50483172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50483172&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			50898777	433950437							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199401	C[C@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m0/s1	QYCJTZDZQXSXSC-JTQLQIEISA-N	50417346	CHEMBL1276220	Alpha-2C adrenergic receptor		 63								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417346&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836303	163366370		CHEMBL1276220					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199404	C(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-2-4-13(12(3-1)9-11-5-6-11)17-10-14-15-7-8-16-14/h1-4,11H,5-10H2,(H,15,16)	OTXMFMMMNBKXQC-UHFFFAOYSA-N	50493430	CHEMBL2431281	Alpha-2C adrenergic receptor		 631								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493430	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493430&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			72947314	433960695							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199409	C(Oc1ccccc1OC1CC1)C1=NCCN1	InChI=1S/C13H16N2O2/c1-2-4-12(17-10-5-6-10)11(3-1)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15)	JFZSEYPHJYDMAZ-UHFFFAOYSA-N	50493431	CHEMBL2431280	Alpha-2C adrenergic receptor		 794								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493431	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493431&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			72947315	433960696							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199410	CC(Oc1ccccc1OC1CC1)C1=NCCN1	InChI=1S/C14H18N2O2/c1-10(14-15-8-9-16-14)17-12-4-2-3-5-13(12)18-11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	OHLOMHGVALXPJP-UHFFFAOYSA-N	50419880	CHEMBL1956197	Alpha-2C adrenergic receptor					 48					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419880&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345629	163368904		CHEMBL1956197				ZINC73312422	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199420	Brc1ccccc1OCC1=NCCN1	InChI=1S/C10H11BrN2O/c11-8-3-1-2-4-9(8)14-7-10-12-5-6-13-10/h1-4H,5-7H2,(H,12,13)	KSQOPRCDYFOHET-UHFFFAOYSA-N	50493432	CHEMBL2431279	Alpha-2C adrenergic receptor		 398								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493432&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			28918670	433960697							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199423	CC(Oc1ccccc1OC1CC1)C1=NCCN1	InChI=1S/C14H18N2O2/c1-10(14-15-8-9-16-14)17-12-4-2-3-5-13(12)18-11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	OHLOMHGVALXPJP-UHFFFAOYSA-N	50419880	CHEMBL1956197	Alpha-2C adrenergic receptor		 676								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419880&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345629	163368904		CHEMBL1956197				ZINC73312422	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199424	CCCc1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)	NFKNRFTZWQGNTI-UHFFFAOYSA-N	50493433	CHEMBL2431282	Alpha-2C adrenergic receptor		 148								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493433&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			73291731	433960698							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199425	C[C@@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m1/s1	QYCJTZDZQXSXSC-SNVBAGLBSA-N	50417345	CHEMBL1276219	Alpha-2C adrenergic receptor		 126								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417345&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836304	163366369		CHEMBL1276219					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199426	C[C@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m0/s1	SEKAQUSPSDPIAN-NSHDSACASA-N	50420342	CHEMBL2089156	Alpha-2C adrenergic receptor		 275								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70695474	163369366		CHEMBL2089156					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199427	C[C@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m0/s1	MNMDMCKHXVHLAW-NSHDSACASA-N	50417343	CHEMBL1276140	Alpha-2C adrenergic receptor		 71								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417343&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836301	163366367		CHEMBL1276140				ZINC40957102	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199428	C[C@@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m1/s1	MNMDMCKHXVHLAW-LLVKDONJSA-N	50417342	CHEMBL1276139	Alpha-2C adrenergic receptor		 178								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836302	163366366		CHEMBL1276139				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199441	CCCc1ccccc1OCC1=NCCN1	InChI=1S/C13H18N2O/c1-2-5-11-6-3-4-7-12(11)16-10-13-14-8-9-15-13/h3-4,6-7H,2,5,8-10H2,1H3,(H,14,15)	KJTFLBJQHBFQAF-UHFFFAOYSA-N	50473179	CHEMBL13917	Alpha-2C adrenergic receptor					 155					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473179&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269013	433940444							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199442	C(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15)	YAORIDZYZDUZCM-UHFFFAOYSA-N	50027060	2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole::2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole (cirazoline)::CHEMBL13852::CIRAZOLINE	Alpha-2C adrenergic receptor					 398					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027060&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2765	103936642		CHEMBL13852	DB09202	515		ZINC00001160	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199443	CC(Oc1ccccc1Br)C1=NCCN1	InChI=1S/C11H13BrN2O/c1-8(11-13-6-7-14-11)15-10-5-3-2-4-9(10)12/h2-5,8H,6-7H2,1H3,(H,13,14)	NFGYJBCMYUYKCI-UHFFFAOYSA-N	50419874	CHEMBL1956192	Alpha-2C adrenergic receptor					 10.0					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419874&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345626	163368898		CHEMBL1956192				ZINC73315479	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199444	CCCc1ccccc1OC(C)C1=NCCN1	InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)	NFKNRFTZWQGNTI-UHFFFAOYSA-N	50493433	CHEMBL2431282	Alpha-2C adrenergic receptor					 25					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493433&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			73291731	433960698							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199445	CC(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	QYCJTZDZQXSXSC-UHFFFAOYSA-N	50417344	CHEMBL1276218	Alpha-2C adrenergic receptor					 40					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417344&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44549156	163366368		CHEMBL1276218				ZINC64393121	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199446	C[C@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m0/s1	MNMDMCKHXVHLAW-NSHDSACASA-N	50417343	CHEMBL1276140	Alpha-2C adrenergic receptor					 25					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417343&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836301	163366367		CHEMBL1276140				ZINC40957102	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199447	C[C@@H](Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)/t11-/m1/s1	MNMDMCKHXVHLAW-LLVKDONJSA-N	50417342	CHEMBL1276139	Alpha-2C adrenergic receptor					 186					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836302	163366366		CHEMBL1276139				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199455	CC(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)	SEKAQUSPSDPIAN-UHFFFAOYSA-N	50419878	CHEMBL1956195	Alpha-2C adrenergic receptor					 2.0					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419878&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345628	163368902		CHEMBL1956195				ZINC73294767	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199458	CC(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)	QYCJTZDZQXSXSC-UHFFFAOYSA-N	50417344	CHEMBL1276218	Alpha-2C adrenergic receptor		 79								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417344&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44549156	163366368		CHEMBL1276218				ZINC64393121	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199461	C=CCc1ccccc1OCC1=NCCN1	InChI=1S/C13H16N2O/c1-2-5-11-6-3-4-7-12(11)16-10-13-14-8-9-15-13/h2-4,6-7H,1,5,8-10H2,(H,14,15)	YFPXOLILPOTYIP-UHFFFAOYSA-N	50473154	CHEMBL14107	Alpha-2C adrenergic receptor					 62					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473154	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473154&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269006	433940419							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199463	CC(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)	SEKAQUSPSDPIAN-UHFFFAOYSA-N	50419878	CHEMBL1956195	Alpha-2C adrenergic receptor		 275								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419878&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345628	163368902		CHEMBL1956195				ZINC73294767	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199464	C1CN=C(N1)c1cc2ccccc2o1	InChI=1S/C11H10N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-4,7H,5-6H2,(H,12,13)	YTJOHEUHUVBKSB-UHFFFAOYSA-N	50086502	2-BFi::2-Benzofuran-2-yl-4,5-dihydro-1H-imidazole::CHEMBL404505	Alpha-2C adrenergic receptor		 26915								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086502&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3080926	103985710		CHEMBL404505				ZINC02567727	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199465	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2C adrenergic receptor					 50					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199467	CCCc1ccccc1OCC1=NCCN1	InChI=1S/C13H18N2O/c1-2-5-11-6-3-4-7-12(11)16-10-13-14-8-9-15-13/h3-4,6-7H,2,5,8-10H2,1H3,(H,14,15)	KJTFLBJQHBFQAF-UHFFFAOYSA-N	50473179	CHEMBL13917	Alpha-2C adrenergic receptor		 490								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473179&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269013	433940444							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199468	C=CCc1ccccc1OCC1=NCCN1	InChI=1S/C13H16N2O/c1-2-5-11-6-3-4-7-12(11)16-10-13-14-8-9-15-13/h2-4,6-7H,1,5,8-10H2,(H,14,15)	YFPXOLILPOTYIP-UHFFFAOYSA-N	50473154	CHEMBL14107	Alpha-2C adrenergic receptor		 71								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473154	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473154&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44269006	433940419							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199472	C[C@@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m1/s1	SEKAQUSPSDPIAN-LLVKDONJSA-N	50420341	CHEMBL2089155	Alpha-2C adrenergic receptor					 316					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420341&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70693375	163369365		CHEMBL2089155					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199476	C[C@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m0/s1	SEKAQUSPSDPIAN-NSHDSACASA-N	50420342	CHEMBL2089156	Alpha-2C adrenergic receptor					 2.0					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420342&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70695474	163369366		CHEMBL2089156					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199479	Brc1ccccc1OCC1=NCCN1	InChI=1S/C10H11BrN2O/c11-8-3-1-2-4-9(8)14-7-10-12-5-6-13-10/h1-4H,5-7H2,(H,12,13)	KSQOPRCDYFOHET-UHFFFAOYSA-N	50493432	CHEMBL2431279	Alpha-2C adrenergic receptor					 98					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493432&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			28918670	433960697							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199484	CC(Oc1ccccc1Br)C1=NCCN1	InChI=1S/C11H13BrN2O/c1-8(11-13-6-7-14-11)15-10-5-3-2-4-9(10)12/h2-5,8H,6-7H2,1H3,(H,13,14)	NFGYJBCMYUYKCI-UHFFFAOYSA-N	50419874	CHEMBL1956192	Alpha-2C adrenergic receptor		 282								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50419874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50419874&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345626	163368898		CHEMBL1956192				ZINC73315479	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199485	C[C@@H](Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C15H20N2O/c1-11(15-16-8-9-17-15)18-14-5-3-2-4-13(14)10-12-6-7-12/h2-5,11-12H,6-10H2,1H3,(H,16,17)/t11-/m1/s1	SEKAQUSPSDPIAN-LLVKDONJSA-N	50420341	CHEMBL2089155	Alpha-2C adrenergic receptor		 234								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420341&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			70693375	163369365		CHEMBL2089155					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199491	C(Oc1ccccc1OC1CC1)C1=NCCN1	InChI=1S/C13H16N2O2/c1-2-4-12(17-10-5-6-10)11(3-1)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15)	JFZSEYPHJYDMAZ-UHFFFAOYSA-N	50493431	CHEMBL2431280	Alpha-2C adrenergic receptor					 1000					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493431	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493431&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			72947315	433960696							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199492	C[C@@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m1/s1	QYCJTZDZQXSXSC-SNVBAGLBSA-N	50417345	CHEMBL1276219	Alpha-2C adrenergic receptor					 126					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417345&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836304	163366369		CHEMBL1276219					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199499	C(Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15)	YAORIDZYZDUZCM-UHFFFAOYSA-N	50027060	2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole::2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole (cirazoline)::CHEMBL13852::CIRAZOLINE	Alpha-2C adrenergic receptor		 550								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027060&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			2765	103936642		CHEMBL13852	DB09202	515		ZINC00001160	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199500	CC(Oc1ccccc1CC=C)C1=NCCN1	InChI=1S/C14H18N2O/c1-3-6-12-7-4-5-8-13(12)17-11(2)14-15-9-10-16-14/h3-5,7-8,11H,1,6,9-10H2,2H3,(H,15,16)	MNMDMCKHXVHLAW-UHFFFAOYSA-N	50412245	CHEMBL495095	Alpha-2C adrenergic receptor		 85								ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50412245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50412245&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24906198	163361269		CHEMBL495095				ZINC40957105	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199502	C[C@H](Oc1ccccc1C1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-10(14-15-8-9-16-14)17-13-5-3-2-4-12(13)11-6-7-11/h2-5,10-11H,6-9H2,1H3,(H,15,16)/t10-/m0/s1	QYCJTZDZQXSXSC-JTQLQIEISA-N	50417346	CHEMBL1276220	Alpha-2C adrenergic receptor					 35					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50417346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50417346&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			49836303	163366370		CHEMBL1276220					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51199504	C(Oc1ccccc1CC1CC1)C1=NCCN1	InChI=1S/C14H18N2O/c1-2-4-13(12(3-1)9-11-5-6-11)17-10-14-15-7-8-16-14/h1-4,11H,5-10H2,(H,15,16)	OTXMFMMMNBKXQC-UHFFFAOYSA-N	50493430	CHEMBL2431281	Alpha-2C adrenergic receptor					 234					ChEMBL	10.1021/ml400232p	10.7270/Q2H134ZZ	24900763			Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M	University of Camerino	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493430	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493430&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			72947314	433960695							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51210375	C1CNC(N1)=Nn1ncc2ccccc12	InChI=1S/C10H11N5/c1-2-4-9-8(3-1)7-13-15(9)14-10-11-5-6-12-10/h1-4,7H,5-6H2,(H2,11,12,14)	PFTFJTOQCWYCNM-UHFFFAOYSA-N	50271255	1-[(Imidazolidin-2-yl)imino]indazole hydrochloride::CHEMBL1186220::CHEMBL454712	Alpha-2C adrenergic receptor		 640								ChEMBL	10.1016/j.ejmech.2014.09.083	10.7270/Q2MW2M45	25282262			Wasilewska, A; Sączewski, F; Hudson, AL; Ferdousi, M; Scheinin, M; Laurila, JM; Rybczyńska, A; Boblewski, K; Lehmann, A	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271255&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			24882007	104116144		CHEMBL454712CHEMBL1186220				ZINC40846960	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51210395	Fc1ccc2cnn(N=C3NCCN3)c2c1	InChI=1S/C10H10FN5/c11-8-2-1-7-6-14-16(9(7)5-8)15-10-12-3-4-13-10/h1-2,5-6H,3-4H2,(H2,12,13,15)	IYLGKCYRBQLWIN-UHFFFAOYSA-N	50497435	CHEMBL3343699	Alpha-2C adrenergic receptor		 600								ChEMBL	10.1016/j.ejmech.2014.09.083	10.7270/Q2MW2M45	25282262			Wasilewska, A; Sączewski, F; Hudson, AL; Ferdousi, M; Scheinin, M; Laurila, JM; Rybczyńska, A; Boblewski, K; Lehmann, A	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50497435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50497435&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118717248	433964700							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51210396	Fc1cccc2cnn(N=C3NCCN3)c12	InChI=1S/C10H10FN5/c11-8-3-1-2-7-6-14-16(9(7)8)15-10-12-4-5-13-10/h1-3,6H,4-5H2,(H2,12,13,15)	NGEQXHFDGLOZSS-UHFFFAOYSA-N	50497439	CHEMBL3343700	Alpha-2C adrenergic receptor		 1200								ChEMBL	10.1016/j.ejmech.2014.09.083	10.7270/Q2MW2M45	25282262			Wasilewska, A; Sączewski, F; Hudson, AL; Ferdousi, M; Scheinin, M; Laurila, JM; Rybczyńska, A; Boblewski, K; Lehmann, A	Medical University of Gdansk	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50497439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50497439&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			118717249	433964704							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51214961	CB1Nc2cccc(OCC(O)CN(C)C)c2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-12-13(16-15)5-4-6-14(12)19-10-11(18)9-17(2)3/h4-8,11,16,18H,9-10H2,1-3H3	KVVLFJLSBAOKPZ-UHFFFAOYSA-N	50499311	CHEMBL3736156	Alpha-2C adrenergic receptor					<5012					ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499311&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034967	433911212							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51215023	CC(C)NCC(O)COc1cccc2ccccc12	InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3	AQHHHDLHHXJYJD-UHFFFAOYSA-N	25761	Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine	Alpha-2C adrenergic receptor			<5012							ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	SNP	1DY4,6EKZ,6PS5,5FUK	4946	56413049	8499	CHEMBL27	DB00571	564	C07407	ZINC00056556	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51215024	CB1Nc2c(OCC(O)CN(C)C)cccc2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-11-5-4-6-13(14(11)16-15)19-10-12(18)9-17(2)3/h4-8,12,16,18H,9-10H2,1-3H3	CCSPGLLRANVKRG-UHFFFAOYSA-N	50499310	CHEMBL3736433	Alpha-2C adrenergic receptor			<5012							ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499310&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034966	433911211							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51215025	CB1Nc2cccc(OCC(O)CN(C)C)c2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-12-13(16-15)5-4-6-14(12)19-10-11(18)9-17(2)3/h4-8,11,16,18H,9-10H2,1-3H3	KVVLFJLSBAOKPZ-UHFFFAOYSA-N	50499311	CHEMBL3736156	Alpha-2C adrenergic receptor			<5012							ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499311&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034967	433911212							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51215050	CC(C)NCC(O)COc1cccc2ccccc12	InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3	AQHHHDLHHXJYJD-UHFFFAOYSA-N	25761	Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine	Alpha-2C adrenergic receptor					<5012					ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	SNP	1DY4,6EKZ,6PS5,5FUK	4946	56413049	8499	CHEMBL27	DB00571	564	C07407	ZINC00056556	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51215093	CB1Nc2c(OCC(O)CN(C)C)cccc2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-11-5-4-6-13(14(11)16-15)19-10-12(18)9-17(2)3/h4-8,12,16,18H,9-10H2,1-3H3	CCSPGLLRANVKRG-UHFFFAOYSA-N	50499310	CHEMBL3736433	Alpha-2C adrenergic receptor					<5012					ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499310&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034966	433911211							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51214228	CNCc1cc(OCc2ccc3ccc(N)nc3c2)ccc1Cl	InChI=1S/C18H18ClN3O/c1-21-10-14-9-15(5-6-16(14)19)23-11-12-2-3-13-4-7-18(20)22-17(13)8-12/h2-9,21H,10-11H2,1H3,(H2,20,22)	SVDORCPNIHFYFA-UHFFFAOYSA-N	344422	US9783500, Compound 17	Alpha-2C adrenergic receptor		<100								ChEMBL	10.1021/acs.jmedchem.5b01330	10.7270/Q2R214C3	26469213			Cinelli, MA; Li, H; Pensa, AV; Kang, S; Roman, LJ; Martásek, P; Poulos, TL; Silverman, RB	Northwestern University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=344422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=344422&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	XEB	5G6L,5FJ3,5FJ2,5ADG,5ADE,5ADB	91971388	385450508							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51224187	C[C@@]12CN(c3ccccc3)c3ccccc3[C@@H]1CCN2	InChI=1S/C18H20N2/c1-18-13-20(14-7-3-2-4-8-14)17-10-6-5-9-15(17)16(18)11-12-19-18/h2-10,16,19H,11-13H2,1H3/t16-,18+/m0/s1	OHCPINQLTJGNRS-FUHWJXTLSA-N	50503048	CHEMBL4457754	Alpha-2C adrenergic receptor		 1000								ChEMBL	10.1021/acsmedchemlett.9b00225	10.7270/Q2DF6VGQ	31620230			Porter, MR; Xiao, H; Wang, J; Smith, SB; Topczewski, JJ	University of Minnesota Twin Cities	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503048	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503048&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			153287553	440711633							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51224230	CC[C@H]1c2ccccc2N(C[C@@]1(C)N)c1ccccc1	InChI=1S/C18H22N2/c1-3-16-15-11-7-8-12-17(15)20(13-18(16,2)19)14-9-5-4-6-10-14/h4-12,16H,3,13,19H2,1-2H3/t16-,18+/m0/s1	WJDLKMWEXVEBMK-FUHWJXTLSA-N	50503044	CHEMBL4572167	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1021/acsmedchemlett.9b00225	10.7270/Q2DF6VGQ	31620230			Porter, MR; Xiao, H; Wang, J; Smith, SB; Topczewski, JJ	University of Minnesota Twin Cities	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503044	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503044&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			153287574	440711629							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51224320	CC[C@H]1c2cc(OC)ccc2CC[C@@]1(C)N	InChI=1S/C14H21NO/c1-4-13-12-9-11(16-3)6-5-10(12)7-8-14(13,2)15/h5-6,9,13H,4,7-8,15H2,1-3H3/t13-,14+/m0/s1	OTQHFPJXKACHHP-UONOGXRCSA-N	50503047	CHEMBL4472703	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1021/acsmedchemlett.9b00225	10.7270/Q2DF6VGQ	31620230			Porter, MR; Xiao, H; Wang, J; Smith, SB; Topczewski, JJ	University of Minnesota Twin Cities	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503047&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155536080	440711632							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51273905	CC[C@@H]1CN2CCc3c([nH]c4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC	InChI=1S/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1	LELBFTMXCIIKKX-QVRQZEMUSA-N	50474152	CHEBI:6956::CHEMBL299031	Alpha-2C adrenergic receptor		 2320								ChEMBL	10.1021/acs.jmedchem.9b01465	10.7270/Q2P55RW6	31834797			Obeng, S; Kamble, SH; Reeves, ME; Restrepo, LF; Patel, A; Behnke, M; Chear, NJ; Ramanathan, S; Sharma, A; León, F; Hiranita, T; Avery, BA; McMahon, LR; McCurdy, CR	University of Florida	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474152&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3034396	433941417					C09226		1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51273922	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12	InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1	BLGXFZZNTVWLAY-SCYLSFHTSA-N	50013515	(+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester	Alpha-2C adrenergic receptor		 0.800000								ChEMBL	10.1021/acs.jmedchem.9b01465	10.7270/Q2P55RW6	31834797			Obeng, S; Kamble, SH; Reeves, ME; Restrepo, LF; Patel, A; Behnke, M; Chear, NJ; Ramanathan, S; Sharma, A; León, F; Hiranita, T; Avery, BA; McMahon, LR; McCurdy, CR	University of Florida	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			8969	103925641	48565	CHEMBL15245	DB01392	102	C09256	ZINC03860825	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51224380	CC[C@H]1c2cc(C)ccc2OC[C@@]1(C)N	InChI=1S/C13H19NO/c1-4-11-10-7-9(2)5-6-12(10)15-8-13(11,3)14/h5-7,11H,4,8,14H2,1-3H3/t11-,13+/m0/s1	DUGAXFUVLZBESY-WCQYABFASA-N	50503043	CHEMBL4528651	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1021/acsmedchemlett.9b00225	10.7270/Q2DF6VGQ	31620230			Porter, MR; Xiao, H; Wang, J; Smith, SB; Topczewski, JJ	University of Minnesota Twin Cities	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503043&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			153287572	440711628							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51221304	COc1cccc2C(CCCN3CCN(CC3)C3CCCCC3)CCCc12	InChI=1S/C24H38N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3	PHRCDWVPTULQMT-UHFFFAOYSA-N	50048866	1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperazine::1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)propyl]piperazine::1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine::CHEMBL53325::PB-28	Alpha-2C adrenergic receptor		 479								ChEMBL	10.1038/s41586-020-2286-9	10.7270/Q29Z984K	32353859			Gordon, DE; Jang, GM; Bouhaddou, M; Xu, J; Obernier, K; White, KM; O'Meara, MJ; Rezelj, VV; Guo, JZ; Swaney, DL; Tummino, TA; Hüttenhain, R; Kaake, RM; Richards, AL; Tutuncuoglu, B; Foussard, H; Batra, J; Haas, K; Modak, M; Kim, M; Haas, P; Polacco, BJ; Braberg, H; Fabius, JM; Eckhardt, M; Soucheray, M; Bennett, MJ; Cakir, M; McGregor, MJ; Li, Q; Meyer, B; Roesch, F; Vallet, T; Mac Kain, A; Miorin, L; Moreno, E; Naing, ZZC; Zhou, Y; Peng, S; Shi, Y; Zhang, Z; Shen, W; Kirby, IT; Melnyk, JE; Chorba, JS; Lou, K; Dai, SA; Barrio-Hernandez, I; Memon, D; Hernandez-Armenta, C; Lyu, J; Mathy, CJP; Perica, T; Pilla, KB; Ganesan, SJ; Saltzberg, DJ; Rakesh, R; Liu, X; Rosenthal, SB; Calviello, L; Venkataramanan, S; Liboy-Lugo, J; Lin, Y; Huang, XP; Liu, Y; Wankowicz, SA; Bohn, M; Safari, M; Ugur, FS; Koh, C; Savar, NS; Tran, QD; Shengjuler, D; Fletcher, SJ; O'Neal, MC; Cai, Y; Chang, JCJ; Broadhurst, DJ; Klippsten, S; Sharp, PP; Wenzell, NA; Kuzuoglu-Ozturk, D; Wang, HY; Trenker, R; Young, JM; Cavero, DA; Hiatt, J; Roth, TL; Rathore, U; Subramanian, A; Noack, J; Hubert, M; Stroud, RM; Frankel, AD; Rosenberg, OS; Verba, KA; Agard, DA; Ott, M; Emerman, M; Jura, N; von Zastrow, M; Verdin, E; Ashworth, A; Schwartz, O; d'Enfert, C; Mukherjee, S; Jacobson, M; Malik, HS; Fujimori, DG; Ideker, T; Craik, CS; Floor, SN; Fraser, JS; Gross, JD; Sali, A; Roth, BL; Ruggero, D; Taunton, J; Kortemme, T; Beltrao, P; Vignuzzi, M; García-Sastre, A; Shokat, KM; Shoichet, BK; Krogan, NJ	QBI COVID-19 Research Group (QCRG)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048866	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048866&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	YT1	7M93	10474335	103979247		CHEMBL53325		6681		ZINC22931097	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51221305	CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12	InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)	XXSMGPRMXLTPCZ-UHFFFAOYSA-N	50467780	CHEBI:5801::Hydroxychloroquine::acs.jmedchem.1c00409_ST.817::med.21724, Compound 9	Alpha-2C adrenergic receptor		 15849								ChEMBL	10.1038/s41586-020-2286-9	10.7270/Q29Z984K	32353859			Gordon, DE; Jang, GM; Bouhaddou, M; Xu, J; Obernier, K; White, KM; O'Meara, MJ; Rezelj, VV; Guo, JZ; Swaney, DL; Tummino, TA; Hüttenhain, R; Kaake, RM; Richards, AL; Tutuncuoglu, B; Foussard, H; Batra, J; Haas, K; Modak, M; Kim, M; Haas, P; Polacco, BJ; Braberg, H; Fabius, JM; Eckhardt, M; Soucheray, M; Bennett, MJ; Cakir, M; McGregor, MJ; Li, Q; Meyer, B; Roesch, F; Vallet, T; Mac Kain, A; Miorin, L; Moreno, E; Naing, ZZC; Zhou, Y; Peng, S; Shi, Y; Zhang, Z; Shen, W; Kirby, IT; Melnyk, JE; Chorba, JS; Lou, K; Dai, SA; Barrio-Hernandez, I; Memon, D; Hernandez-Armenta, C; Lyu, J; Mathy, CJP; Perica, T; Pilla, KB; Ganesan, SJ; Saltzberg, DJ; Rakesh, R; Liu, X; Rosenthal, SB; Calviello, L; Venkataramanan, S; Liboy-Lugo, J; Lin, Y; Huang, XP; Liu, Y; Wankowicz, SA; Bohn, M; Safari, M; Ugur, FS; Koh, C; Savar, NS; Tran, QD; Shengjuler, D; Fletcher, SJ; O'Neal, MC; Cai, Y; Chang, JCJ; Broadhurst, DJ; Klippsten, S; Sharp, PP; Wenzell, NA; Kuzuoglu-Ozturk, D; Wang, HY; Trenker, R; Young, JM; Cavero, DA; Hiatt, J; Roth, TL; Rathore, U; Subramanian, A; Noack, J; Hubert, M; Stroud, RM; Frankel, AD; Rosenberg, OS; Verba, KA; Agard, DA; Ott, M; Emerman, M; Jura, N; von Zastrow, M; Verdin, E; Ashworth, A; Schwartz, O; d'Enfert, C; Mukherjee, S; Jacobson, M; Malik, HS; Fujimori, DG; Ideker, T; Craik, CS; Floor, SN; Fraser, JS; Gross, JD; Sali, A; Roth, BL; Ruggero, D; Taunton, J; Kortemme, T; Beltrao, P; Vignuzzi, M; García-Sastre, A; Shokat, KM; Shoichet, BK; Krogan, NJ	QBI COVID-19 Research Group (QCRG)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467780&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			3652	433935045					C07043		1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51221313	CCCN1CCC=C(C1)c1cc(no1)-c1ccc(C)cc1	InChI=1S/C18H22N2O/c1-3-10-20-11-4-5-16(13-20)18-12-17(19-21-18)15-8-6-14(2)7-9-15/h5-9,12H,3-4,10-11,13H2,1-2H3	FOQRKFCLRMMKAT-UHFFFAOYSA-N	50251208	CHEMBL4088272	Alpha-2C adrenergic receptor		 10000								ChEMBL	10.1038/s41586-020-2286-9	10.7270/Q29Z984K	32353859			Gordon, DE; Jang, GM; Bouhaddou, M; Xu, J; Obernier, K; White, KM; O'Meara, MJ; Rezelj, VV; Guo, JZ; Swaney, DL; Tummino, TA; Hüttenhain, R; Kaake, RM; Richards, AL; Tutuncuoglu, B; Foussard, H; Batra, J; Haas, K; Modak, M; Kim, M; Haas, P; Polacco, BJ; Braberg, H; Fabius, JM; Eckhardt, M; Soucheray, M; Bennett, MJ; Cakir, M; McGregor, MJ; Li, Q; Meyer, B; Roesch, F; Vallet, T; Mac Kain, A; Miorin, L; Moreno, E; Naing, ZZC; Zhou, Y; Peng, S; Shi, Y; Zhang, Z; Shen, W; Kirby, IT; Melnyk, JE; Chorba, JS; Lou, K; Dai, SA; Barrio-Hernandez, I; Memon, D; Hernandez-Armenta, C; Lyu, J; Mathy, CJP; Perica, T; Pilla, KB; Ganesan, SJ; Saltzberg, DJ; Rakesh, R; Liu, X; Rosenthal, SB; Calviello, L; Venkataramanan, S; Liboy-Lugo, J; Lin, Y; Huang, XP; Liu, Y; Wankowicz, SA; Bohn, M; Safari, M; Ugur, FS; Koh, C; Savar, NS; Tran, QD; Shengjuler, D; Fletcher, SJ; O'Neal, MC; Cai, Y; Chang, JCJ; Broadhurst, DJ; Klippsten, S; Sharp, PP; Wenzell, NA; Kuzuoglu-Ozturk, D; Wang, HY; Trenker, R; Young, JM; Cavero, DA; Hiatt, J; Roth, TL; Rathore, U; Subramanian, A; Noack, J; Hubert, M; Stroud, RM; Frankel, AD; Rosenberg, OS; Verba, KA; Agard, DA; Ott, M; Emerman, M; Jura, N; von Zastrow, M; Verdin, E; Ashworth, A; Schwartz, O; d'Enfert, C; Mukherjee, S; Jacobson, M; Malik, HS; Fujimori, DG; Ideker, T; Craik, CS; Floor, SN; Fraser, JS; Gross, JD; Sali, A; Roth, BL; Ruggero, D; Taunton, J; Kortemme, T; Beltrao, P; Vignuzzi, M; García-Sastre, A; Shokat, KM; Shoichet, BK; Krogan, NJ	QBI COVID-19 Research Group (QCRG)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251208&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	61W	5HK1	9817231	401962647							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51221332	CN1CCC[C@@H]1CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1	InChI=1S/C21H26ClNO/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3/t20-,21-/m1/s1	YNNUSGIPVFPVBX-NHCUHLMSSA-N	50253157	(+)-(2R)-2-(2-(((R)-p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine::(+)-(2R)-2-[2-[[(R)-p-chloro-alpha-methyl-alpha-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine::(2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine::CHEMBL1626::CLEMASTINE	Alpha-2C adrenergic receptor		 224								ChEMBL	10.1038/s41586-020-2286-9	10.7270/Q29Z984K	32353859			Gordon, DE; Jang, GM; Bouhaddou, M; Xu, J; Obernier, K; White, KM; O'Meara, MJ; Rezelj, VV; Guo, JZ; Swaney, DL; Tummino, TA; Hüttenhain, R; Kaake, RM; Richards, AL; Tutuncuoglu, B; Foussard, H; Batra, J; Haas, K; Modak, M; Kim, M; Haas, P; Polacco, BJ; Braberg, H; Fabius, JM; Eckhardt, M; Soucheray, M; Bennett, MJ; Cakir, M; McGregor, MJ; Li, Q; Meyer, B; Roesch, F; Vallet, T; Mac Kain, A; Miorin, L; Moreno, E; Naing, ZZC; Zhou, Y; Peng, S; Shi, Y; Zhang, Z; Shen, W; Kirby, IT; Melnyk, JE; Chorba, JS; Lou, K; Dai, SA; Barrio-Hernandez, I; Memon, D; Hernandez-Armenta, C; Lyu, J; Mathy, CJP; Perica, T; Pilla, KB; Ganesan, SJ; Saltzberg, DJ; Rakesh, R; Liu, X; Rosenthal, SB; Calviello, L; Venkataramanan, S; Liboy-Lugo, J; Lin, Y; Huang, XP; Liu, Y; Wankowicz, SA; Bohn, M; Safari, M; Ugur, FS; Koh, C; Savar, NS; Tran, QD; Shengjuler, D; Fletcher, SJ; O'Neal, MC; Cai, Y; Chang, JCJ; Broadhurst, DJ; Klippsten, S; Sharp, PP; Wenzell, NA; Kuzuoglu-Ozturk, D; Wang, HY; Trenker, R; Young, JM; Cavero, DA; Hiatt, J; Roth, TL; Rathore, U; Subramanian, A; Noack, J; Hubert, M; Stroud, RM; Frankel, AD; Rosenberg, OS; Verba, KA; Agard, DA; Ott, M; Emerman, M; Jura, N; von Zastrow, M; Verdin, E; Ashworth, A; Schwartz, O; d'Enfert, C; Mukherjee, S; Jacobson, M; Malik, HS; Fujimori, DG; Ideker, T; Craik, CS; Floor, SN; Fraser, JS; Gross, JD; Sali, A; Roth, BL; Ruggero, D; Taunton, J; Kortemme, T; Beltrao, P; Vignuzzi, M; García-Sastre, A; Shokat, KM; Shoichet, BK; Krogan, NJ	QBI COVID-19 Research Group (QCRG)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253157	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253157&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			26987	104105756	3738	CHEMBL1626	DB00283	6063	C06913	ZINC00402830	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51224446	COc1cc(OC)c2[C@@H]3CCN[C@]3(C)COc2c1	InChI=1S/C14H19NO3/c1-14-8-18-12-7-9(16-2)6-11(17-3)13(12)10(14)4-5-15-14/h6-7,10,15H,4-5,8H2,1-3H3/t10-,14+/m0/s1	NYBQQHJGLBCUBL-IINYFYTJSA-N	50503049	CHEMBL4447975	Alpha-2C adrenergic receptor		<10000								ChEMBL	10.1021/acsmedchemlett.9b00225	10.7270/Q2DF6VGQ	31620230			Porter, MR; Xiao, H; Wang, J; Smith, SB; Topczewski, JJ	University of Minnesota Twin Cities	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503049	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503049&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155519891	440711634							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51314462	OC(=O)c1cc(cc(c1)-n1cc(nn1)-c1ccc(Cl)s1)-c1ccc(cc1)C1CCNCC1	InChI=1S/C24H21ClN4O2S/c25-23-6-5-22(32-23)21-14-29(28-27-21)20-12-18(11-19(13-20)24(30)31)16-3-1-15(2-4-16)17-7-9-26-10-8-17/h1-6,11-14,17,26H,7-10H2,(H,30,31)	ULWSPLJNOBISBK-UHFFFAOYSA-N	50532693	CHEMBL4544251	Alpha-2C adrenergic receptor		 1320								ChEMBL	10.1021/acs.jmedchem.6b00044	10.7270/Q2DJ5K34	27331270			Junker, A; Balasubramanian, R; Ciancetta, A; Uliassi, E; Kiselev, E; Martiriggiano, C; Trujillo, K; Mtchedlidze, G; Birdwell, L; Brown, KA; Harden, TK; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532693&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			135356876	440741275							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51314491	OC(=O)c1cc(cc(c1)-n1cc(nn1)-c1ccc(Cl)s1)-c1ccc(cc1)C1CCNCC1	InChI=1S/C24H21ClN4O2S/c25-23-6-5-22(32-23)21-14-29(28-27-21)20-12-18(11-19(13-20)24(30)31)16-3-1-15(2-4-16)17-7-9-26-10-8-17/h1-6,11-14,17,26H,7-10H2,(H,30,31)	ULWSPLJNOBISBK-UHFFFAOYSA-N	50532693	CHEMBL4544251	Alpha-2C adrenergic receptor		 1320								ChEMBL	10.1021/acs.jmedchem.6b00044	10.7270/Q2DJ5K34	27331270			Junker, A; Balasubramanian, R; Ciancetta, A; Uliassi, E; Kiselev, E; Martiriggiano, C; Trujillo, K; Mtchedlidze, G; Birdwell, L; Brown, KA; Harden, TK; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532693&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			135356876	440741275							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51287513	COc1ccccc1N1CCC2(CCN(CCCSc3nnc(-c4ccccc4)n3C)CC2)CC1	InChI=1S/C28H37N5OS/c1-31-26(23-9-4-3-5-10-23)29-30-27(31)35-22-8-17-32-18-13-28(14-19-32)15-20-33(21-16-28)24-11-6-7-12-25(24)34-2/h3-7,9-12H,8,13-22H2,1-2H3	KVHHUZUNLIGTBY-UHFFFAOYSA-N	50250795	CHEMBL4084262	Alpha-2C adrenergic receptor		 1557								ChEMBL	10.1021/acs.jmedchem.9b00412	10.7270/Q2Z03CM2	31021617			Reilly, SW; Riad, AA; Hsieh, CJ; Sahlholm, K; Jacome, DA; Griffin, S; Taylor, M; Weng, CC; Xu, K; Kirschner, N; Luedtke, RR; Parry, C; Malhotra, S; Karanicolas, J; Mach, RH	University of Pennsylvania	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50250795	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50250795&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			137645406	401962410							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51287584	COc1ccccc1N1CCN(CCCSc2nnc(-c3ccccc3)n2C)CC1	InChI=1S/C23H29N5OS/c1-26-22(19-9-4-3-5-10-19)24-25-23(26)30-18-8-13-27-14-16-28(17-15-27)20-11-6-7-12-21(20)29-2/h3-7,9-12H,8,13-18H2,1-2H3	RRTCFJGKAMKAIY-UHFFFAOYSA-N	50250803	CHEMBL4083252	Alpha-2C adrenergic receptor		 433								ChEMBL	10.1021/acs.jmedchem.9b00412	10.7270/Q2Z03CM2	31021617			Reilly, SW; Riad, AA; Hsieh, CJ; Sahlholm, K; Jacome, DA; Griffin, S; Taylor, M; Weng, CC; Xu, K; Kirschner, N; Luedtke, RR; Parry, C; Malhotra, S; Karanicolas, J; Mach, RH	University of Pennsylvania	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50250803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50250803&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			137646281	401962417							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51295497	COc1ccc(OCCN2CCN(CC2)C(=O)c2cc3ccccc3[nH]2)cc1	InChI=1S/C22H25N3O3/c1-27-18-6-8-19(9-7-18)28-15-14-24-10-12-25(13-11-24)22(26)21-16-17-4-2-3-5-20(17)23-21/h2-9,16,23H,10-15H2,1H3	HAZPAMUWUHDPDA-UHFFFAOYSA-N	50527972	CHEMBL4476784::US11634404, Compound 1	Alpha-2C adrenergic receptor		 2841								ChEMBL	10.1021/acs.jmedchem.0c00424	10.7270/Q28D00QN	32342685			Moritz, AE; Free, RB; Weiner, WS; Akano, EO; Gandhi, D; Abramyan, A; Keck, TM; Ferrer, M; Hu, X; Southall, N; Steiner, J; Aubé, J; Shi, L; Frankowski, KJ; Sibley, DR	National Institute of Neurological Disorders and Stroke	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50527972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50527972&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			27842480	440736554							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51295587	CCCN[C@H]1CCc2nc(N)sc2C1	InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1	FASDKYOPVNHBLU-ZETCQYMHSA-N	50116766	(-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570	Alpha-2C adrenergic receptor		 52								ChEMBL	10.1021/acs.jmedchem.0c00424	10.7270/Q28D00QN	32342685			Moritz, AE; Free, RB; Weiner, WS; Akano, EO; Gandhi, D; Abramyan, A; Keck, TM; Ferrer, M; Hu, X; Southall, N; Steiner, J; Aubé, J; Shi, L; Frankowski, KJ; Sibley, DR	National Institute of Neurological Disorders and Stroke	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	G6L	7CMU	119570	104010405	8356	CHEMBL301265	DB00413			ZINC03781664	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51333232	Cc1nccc2-c3ccc(Br)cc3NC(C)(C)c12	InChI=1S/C15H15BrN2/c1-9-14-12(6-7-17-9)11-5-4-10(16)8-13(11)18-15(14,2)3/h4-8,18H,1-3H3	YBGLIPYAJPOYAD-UHFFFAOYSA-N	50539742	CHEMBL4642292	Alpha-2C adrenergic receptor		>10000								ChEMBL	10.1021/acs.jnatprod.9b01107	10.7270/Q2KS6W2R	32227883			Kochanowska-Karamyan, AJ; Araujo, HC; Zhang, X; El-Alfy, A; Carvalho, P; Avery, MA; Holmbo, SD; Magolan, J; Hamann, MT	University of Mississippi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539742&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			25235287	442141305							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51334859	Cc1cc(Br)c(NC2=NCCN2)c2ccccc12	InChI=1S/C14H14BrN3/c1-9-8-12(15)13(18-14-16-6-7-17-14)11-5-3-2-4-10(9)11/h2-5,8H,6-7H2,1H3,(H2,16,17,18)	UYAOIRISFNRFCT-UHFFFAOYSA-N	50540286	CHEMBL4636550	Alpha-2C adrenergic receptor			 180							ChEMBL	10.1021/acs.jmedchem.9b01870	10.7270/Q21N84P4	32073845			Mainolfi, N; Ehara, T; Karki, RG; Anderson, K; Mac Sweeney, A; Liao, SM; Argikar, UA; Jendza, K; Zhang, C; Powers, J; Klosowski, DW; Crowley, M; Kawanami, T; Ding, J; April, M; Forster, C; Serrano-Wu, M; Capparelli, M; Ramqaj, R; Solovay, C; Cumin, F; Smith, TM; Ferrara, L; Lee, W; Long, D; Prentiss, M; De Erkenez, A; Yang, L; Liu, F; Sellner, H; Sirockin, F; Valeur, E; Erbel, P; Ostermeier, D; Ramage, P; Gerhartz, B; Schubart, A; Flohr, S; Gradoux, N; Feifel, R; Vogg, B; Wiesmann, C; Maibaum, J; Eder, J; Sedrani, R; Harrison, RA; Mogi, M; Jaffee, BD; Adams, CM	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540286&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	JGT	6QSW	138753277	442141849							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51334890	Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(cc1)C(O)=O			160473	US10093663, Example 25b::US9682968, Example-25a (+)	Alpha-2C adrenergic receptor			>30000							ChEMBL	10.1021/acs.jmedchem.9b01870	10.7270/Q21N84P4	32073845			Mainolfi, N; Ehara, T; Karki, RG; Anderson, K; Mac Sweeney, A; Liao, SM; Argikar, UA; Jendza, K; Zhang, C; Powers, J; Klosowski, DW; Crowley, M; Kawanami, T; Ding, J; April, M; Forster, C; Serrano-Wu, M; Capparelli, M; Ramqaj, R; Solovay, C; Cumin, F; Smith, TM; Ferrara, L; Lee, W; Long, D; Prentiss, M; De Erkenez, A; Yang, L; Liu, F; Sellner, H; Sirockin, F; Valeur, E; Erbel, P; Ostermeier, D; Ramage, P; Gerhartz, B; Schubart, A; Flohr, S; Gradoux, N; Feifel, R; Vogg, B; Wiesmann, C; Maibaum, J; Eder, J; Sedrani, R; Harrison, RA; Mogi, M; Jaffee, BD; Adams, CM	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=160473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=160473&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	VK 	6T8V	90466447	355041951							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51334891	CO[C@H]1CCN(Cc2c(C)cc(C)c3[nH]ccc23)[C@H](CO)C1			50540307	CHEMBL4634827	Alpha-2C adrenergic receptor			 16000							ChEMBL	10.1021/acs.jmedchem.9b01870	10.7270/Q21N84P4	32073845			Mainolfi, N; Ehara, T; Karki, RG; Anderson, K; Mac Sweeney, A; Liao, SM; Argikar, UA; Jendza, K; Zhang, C; Powers, J; Klosowski, DW; Crowley, M; Kawanami, T; Ding, J; April, M; Forster, C; Serrano-Wu, M; Capparelli, M; Ramqaj, R; Solovay, C; Cumin, F; Smith, TM; Ferrara, L; Lee, W; Long, D; Prentiss, M; De Erkenez, A; Yang, L; Liu, F; Sellner, H; Sirockin, F; Valeur, E; Erbel, P; Ostermeier, D; Ramage, P; Gerhartz, B; Schubart, A; Flohr, S; Gradoux, N; Feifel, R; Vogg, B; Wiesmann, C; Maibaum, J; Eder, J; Sedrani, R; Harrison, RA; Mogi, M; Jaffee, BD; Adams, CM	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540307&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	JGN	6QSX	138753276	442141870							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51342138	OC(=O)c1cc(cc(c1)-c1ccc(cc1)C1CCNCC1)-c1cn(nn1)-c1ccc(cc1)C(F)(F)F	InChI=1S/C27H23F3N4O2/c28-27(29,30)23-5-7-24(8-6-23)34-16-25(32-33-34)21-13-20(14-22(15-21)26(35)36)18-3-1-17(2-4-18)19-9-11-31-12-10-19/h1-8,13-16,19,31H,9-12H2,(H,35,36)	WYKMWZDXNRNMFC-UHFFFAOYSA-N	50541996	CHEMBL4633982	Alpha-2C adrenergic receptor		 2710								ChEMBL	10.1021/acs.jmedchem.0c00745	10.7270/Q20R9SZP	32787142			Jung, YH; Yu, J; Wen, Z; Salmaso, V; Karcz, TP; Phung, NB; Chen, Z; Duca, S; Bennett, JM; Dudas, S; Salvemini, D; Gao, ZG; Cook, DN; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50541996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50541996&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			139406787	442143559							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51365957	CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1	InChI=1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1	QHMBSVQNZZTUGM-ZWKOTPCHSA-N	50318484	2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)-5-pentyl-benzene-1,3-diol::CANNABIDIOL::CHEMBL190461	Alpha-2C adrenergic receptor		 3700								ChEMBL	10.1021/acs.jmedchem.0c00724	10.7270/Q2697778	32804502			Nelson, KM; Bisson, J; Singh, G; Graham, JG; Chen, SN; Friesen, JB; Dahlin, JL; Niemitz, M; Walters, MA; Pauli, GF	University of Minnesota	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50318484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50318484&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	P0T	8FX8,7TE8,8FXG,6U88,6U8A,7T37	644019	104152845	69478	CHEMBL190461		4150	C07578	ZINC04097406	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51410038	OC(=O)c1ccc(cc1)C#Cc1ccc2OC(C(=Cc2c1)[N+]([O-])=O)C(F)(F)F	InChI=1S/C19H10F3NO5/c20-19(21,22)17-15(23(26)27)10-14-9-12(5-8-16(14)28-17)2-1-11-3-6-13(7-4-11)18(24)25/h3-10,17H,(H,24,25)	YHEJLDMRDBHXIJ-UHFFFAOYSA-N	50569559	CHEMBL4857492	Alpha-2C adrenergic receptor		 2600								ChEMBL	10.1016/j.bmcl.2021.128008	10.7270/Q2C2516Q	33831560			Jung, YH; Jain, S; Gopinatth, V; Phung, NB; Gao, ZG; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50569559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50569559&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			164615845	471059704							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51402065	CC(=O)N1CCC(CC1)c1ccc(cc1)-c1cc(cc2cc(ccc12)-c1ccc(cc1)C(F)(F)F)C(O)=O	InChI=1S/C31H26F3NO3/c1-19(36)35-14-12-22(13-15-35)20-2-4-23(5-3-20)29-18-26(30(37)38)17-25-16-24(8-11-28(25)29)21-6-9-27(10-7-21)31(32,33)34/h2-11,16-18,22H,12-15H2,1H3,(H,37,38)	AFRXCTUPOJKNDG-UHFFFAOYSA-N	50541998	CHEMBL4642592	Alpha-2C adrenergic receptor		 4310								ChEMBL	10.1021/acs.jmedchem.1c00164	10.7270/Q2BZ69SP	33787273			Jung, YH; Salmaso, V; Wen, Z; Bennett, JM; Phung, NB; Lieberman, DI; Gopinatth, V; Randle, JCR; Chen, Z; Salvemini, D; Karcz, TP; Cook, DN; Jacobson, KA	National Institute of Diabetes and Digestive and Kidney Diseases	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50541998	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50541998&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155770281	442143561							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51420267	CC(C)C[C@@H](N)C(=O)Nc1ccc(-c2cnco2)c(OC(F)F)c1	InChI=1S/C16H19F2N3O3/c1-9(2)5-12(19)15(22)21-10-3-4-11(14-7-20-8-23-14)13(6-10)24-16(17)18/h3-4,6-9,12,16H,5,19H2,1-2H3,(H,21,22)/t12-/m1/s1	GCTFTMWXZFLTRR-GFCCVEGCSA-N	50573682	CHEMBL4872886	Alpha-2C adrenergic receptor			>30000							ChEMBL	10.1021/acs.jmedchem.1c00472	10.7270/Q2WQ07KF	34270254			Hartz, RA; Ahuja, VT; Nara, SJ; Kumar, CMV; Brown, JM; Bristow, LJ; Rajamani, R; Muckelbauer, JK; Camac, D; Kiefer, SE; Hunihan, L; Gulianello, M; Lewis, M; Easton, A; Lippy, JS; Surti, N; Pattipati, SN; Dokania, M; Elavazhagan, S; Dandapani, K; Hamman, BD; Allen, J; Kostich, W; Bronson, JJ; Macor, JE; Dzierba, CD	Bristol Myers Squibb Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50573682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50573682&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	5QI	7RJ8	86582964	471063827							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51421469	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COC3CCC3)C2)c(F)c1	InChI=1S/C25H33F2N5O2S/c26-18-11-21(27)22(28-12-18)13-29-24(33)23-14-30-25(35-23)31-9-6-19(7-10-31)32-8-2-3-17(15-32)16-34-20-4-1-5-20/h11-12,14,17,19-20H,1-10,13,15-16H2,(H,29,33)	KMNWWCLNNWZFIT-UHFFFAOYSA-N	50574215	CHEMBL4878875	Alpha-2C adrenergic receptor			 0.085000							ChEMBL	10.1021/acsmedchemlett.1c00423	10.7270/Q2183BBF	34531943			Sabnis, RW	Smith, Gambrell & Russell LLP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574215	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574215&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735109	471064360							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51421470	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CC2(F)F)c(F)c1	InChI=1S/C24H29F4N5O2S/c25-16-8-19(26)20(29-10-16)11-30-22(34)21-12-31-23(36-21)32-6-3-17(4-7-32)33-5-1-2-18(13-33)35-14-15-9-24(15,27)28/h8,10,12,15,17-18H,1-7,9,11,13-14H2,(H,30,34)	YAJMPZFDYPOFQB-UHFFFAOYSA-N	50574216	CHEMBL4876214	Alpha-2C adrenergic receptor			 0.370000							ChEMBL	10.1021/acsmedchemlett.1c00423	10.7270/Q2183BBF	34531943			Sabnis, RW	Smith, Gambrell & Russell LLP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574216&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735115	471064361							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51421471	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CCC2)c(F)c1	InChI=1S/C25H33F2N5O2S/c26-18-11-21(27)22(28-12-18)13-29-24(33)23-14-30-25(35-23)31-9-6-19(7-10-31)32-8-2-5-20(15-32)34-16-17-3-1-4-17/h11-12,14,17,19-20H,1-10,13,15-16H2,(H,29,33)	JLGCDTMMQVNEKF-UHFFFAOYSA-N	50574217	CHEMBL4866383	Alpha-2C adrenergic receptor			 0.490000							ChEMBL	10.1021/acsmedchemlett.1c00423	10.7270/Q2183BBF	34531943			Sabnis, RW	Smith, Gambrell & Russell LLP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574217&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735188	471064362							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51421472	FC1CN(CCC1N1CCCC2(CC2)C1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H26F3N5OS/c23-14-8-15(24)17(26-9-14)10-27-20(31)19-11-28-21(32-19)29-7-2-18(16(25)12-29)30-6-1-3-22(13-30)4-5-22/h8-9,11,16,18H,1-7,10,12-13H2,(H,27,31)	LKPAKMYDZQMMOO-UHFFFAOYSA-N	50574218	CHEMBL4875484	Alpha-2C adrenergic receptor			 0.260000							ChEMBL	10.1021/acsmedchemlett.1c00423	10.7270/Q2183BBF	34531943			Sabnis, RW	Smith, Gambrell & Russell LLP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574218&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735161	471064363							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51421473	COc1cccc2CCN(Cc12)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C25H27F2N5O2S/c1-34-22-4-2-3-16-5-8-32(15-19(16)22)18-6-9-31(10-7-18)25-30-14-23(35-25)24(33)29-13-21-20(27)11-17(26)12-28-21/h2-4,11-12,14,18H,5-10,13,15H2,1H3,(H,29,33)	YBUVVPDQNUYGOE-UHFFFAOYSA-N	50574219	CHEMBL4852159	Alpha-2C adrenergic receptor			 0.320000							ChEMBL	10.1021/acsmedchemlett.1c00423	10.7270/Q2183BBF	34531943			Sabnis, RW	Smith, Gambrell & Russell LLP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574219	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574219&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			164617361	471064364							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51421474	Cc1ccc2CCN(Cc2c1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C25H27F2N5OS/c1-16-2-3-17-4-7-32(15-18(17)10-16)20-5-8-31(9-6-20)25-30-14-23(34-25)24(33)29-13-22-21(27)11-19(26)12-28-22/h2-3,10-12,14,20H,4-9,13,15H2,1H3,(H,29,33)	KYGWRYJIKUTQPQ-UHFFFAOYSA-N	50574220	CHEMBL4868807	Alpha-2C adrenergic receptor			 0.420000							ChEMBL	10.1021/acsmedchemlett.1c00423	10.7270/Q2183BBF	34531943			Sabnis, RW	Smith, Gambrell & Russell LLP	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574220	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574220&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735204	471064365							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51450979	NCCCCN(C[C@H]1Cc2ccccc2CN1)[C@H]1CCCc2cccnc12	InChI=1S/C23H32N4/c24-12-3-4-14-27(22-11-5-9-18-10-6-13-25-23(18)22)17-21-15-19-7-1-2-8-20(19)16-26-21/h1-2,6-8,10,13,21-22,26H,3-5,9,11-12,14-17,24H2/t21-,22+/m1/s1	MYCKNKHATQGHEV-YADHBBJMSA-N	50443541	CHEMBL3091687	Alpha-2C adrenergic receptor			 23000							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50443541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50443541&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			57345320	194941437		CHEMBL3091687					1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51450980	NCCCCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12	InChI=1S/C22H31N5/c23-10-1-2-13-27(21-9-3-6-17-7-4-12-25-22(17)21)16-19-14-20-18(15-26-19)8-5-11-24-20/h4-5,7-8,11-12,19,21,26H,1-3,6,9-10,13-16,23H2/t19-,21+/m1/s1	AJBIIZLEMNVANQ-CTNGQTDRSA-N	50585788	CHEMBL5070958	Alpha-2C adrenergic receptor			 13000							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585788	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585788&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			163196369	476021875							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51450981	NCCCCN(C[C@H]1Cc2cccnc2CN1)[C@H]1CCCc2cccnc12	InChI=1S/C22H31N5/c23-10-1-2-13-27(21-9-3-6-17-7-4-12-25-22(17)21)16-19-14-18-8-5-11-24-20(18)15-26-19/h4-5,7-8,11-12,19,21,26H,1-3,6,9-10,13-16,23H2/t19-,21+/m1/s1	SASWWPISKHTFAO-CTNGQTDRSA-N	50585790	CHEMBL5076569	Alpha-2C adrenergic receptor			 30000							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585790	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585790&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166626034	476021877							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51450982	CN(CCCCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12)C1CCC(F)(F)CC1	InChI=1S/C29H41F2N5/c1-35(25-11-13-29(30,31)14-12-25)17-2-3-18-36(27-10-4-7-22-8-5-16-33-28(22)27)21-24-19-26-23(20-34-24)9-6-15-32-26/h5-6,8-9,15-16,24-25,27,34H,2-4,7,10-14,17-21H2,1H3/t24-,27+/m1/s1	OSKSLFQSLKWAIH-SQHAQQRYSA-N	50585805	CHEMBL5093818	Alpha-2C adrenergic receptor			>30000							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585805&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155807735	476021892							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51450983	C(CCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12)CNC1CCOCC1	InChI=1S/C27H39N5O/c1(12-28-23-10-16-33-17-11-23)2-15-32(26-9-3-6-21-7-4-14-30-27(21)26)20-24-18-25-22(19-31-24)8-5-13-29-25/h4-5,7-8,13-14,23-24,26,28,31H,1-3,6,9-12,15-20H2/t24-,26+/m1/s1	POWOJVYGOJPOQL-RSXGOPAZSA-N	50585806	CHEMBL5085511	Alpha-2C adrenergic receptor			>30000							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585806	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585806&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166631293	476021893							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51450984	CN(CCCCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12)C1CCOCC1	InChI=1S/C28H41N5O/c1-32(25-11-17-34-18-12-25)15-2-3-16-33(27-10-4-7-22-8-5-14-30-28(22)27)21-24-19-26-23(20-31-24)9-6-13-29-26/h5-6,8-9,13-14,24-25,27,31H,2-4,7,10-12,15-21H2,1H3/t24-,27+/m1/s1	IEQLWCFKWYLMAM-SQHAQQRYSA-N	50585807	CHEMBL5077132	Alpha-2C adrenergic receptor			 8400							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585807&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166626056	476021894							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51450985	C(CCN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12)CNC1COC1	InChI=1S/C25H35N5O/c1(10-26-22-17-31-18-22)2-13-30(24-9-3-6-19-7-4-12-28-25(19)24)16-21-14-23-20(15-29-21)8-5-11-27-23/h4-5,7-8,11-12,21-22,24,26,29H,1-3,6,9-10,13-18H2/t21-,24+/m1/s1	HCFZOYBEELAHRR-QPPBQGQZSA-N	50585808	CHEMBL5083458	Alpha-2C adrenergic receptor			 8800							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585808	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585808&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166627357	476021895							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51450986	C(CC1CCNCC1)CN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12	InChI=1S/C26H37N5/c1-6-21-7-2-13-29-26(21)25(9-1)31(16-4-5-20-10-14-27-15-11-20)19-23-17-24-22(18-30-23)8-3-12-28-24/h2-3,7-8,12-13,20,23,25,27,30H,1,4-6,9-11,14-19H2/t23-,25+/m1/s1	WOELGNYRXZQOPS-NOZRDPDXSA-N	50585810	CHEMBL5081505	Alpha-2C adrenergic receptor			 2200							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585810&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			155808034	476021897							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51450987	C(CCN1CCOCC1)CN(C[C@H]1Cc2ncccc2CN1)[C@H]1CCCc2cccnc12	InChI=1S/C26H37N5O/c1(12-30-14-16-32-17-15-30)2-13-31(25-9-3-6-21-7-4-11-28-26(21)25)20-23-18-24-22(19-29-23)8-5-10-27-24/h4-5,7-8,10-11,23,25,29H,1-3,6,9,12-20H2/t23-,25+/m1/s1	STAHMXIYSLAGBJ-NOZRDPDXSA-N	50585811	CHEMBL5082142	Alpha-2C adrenergic receptor			 20000							ChEMBL	10.1021/acs.jmedchem.1c01564	10.7270/Q23X8BKN	35179893			Jecs, E; Tahirovic, YA; Wilson, RJ; Miller, EJ; Kim, M; Truax, V; Nguyen, HH; Akins, NS; Saindane, M; Wang, T; Sum, CS; Cvijic, ME; Schroeder, GM; Burton, SL; Derdeyn, CA; Xu, L; Jiang, Y; Wilson, LJ; Liotta, DC	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585811&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166629813	476021898							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51468663	CN1CCN(CC1(C)C)[C@@H]1C[C@H](c2ccc(Cl)cc12)c1ccccc1	InChI=1S/C22H27ClN2/c1-22(2)15-25(12-11-24(22)3)21-14-19(16-7-5-4-6-8-16)18-10-9-17(23)13-20(18)21/h4-10,13,19,21H,11-12,14-15H2,1-3H3/t19-,21+/m0/s1	BYPMJBXPNZMNQD-PZJWPPBQSA-N	50547397	LU-31-130::Lu 31-130::Zicronapine	Alpha-2C adrenergic receptor		 9.7								ChEMBL		10.7270/Q2P27346	35809818			Gjervig Jensen, K; Tornby Christoffersen, C; Graulund Hvenegaard, M; Didriksen, M; Jørgensen, M	H. Lundbeck A/S	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50547397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50547397&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			11465618	461691160							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51468664	[2H]c1c([2H])c([2H])c([C@@H]2C[C@@H](N3CCNC(C)(C)C3)c3cc(Cl)ccc23)c([2H])c1[2H]	InChI=1S/C21H25ClN2/c1-21(2)14-24(11-10-23-21)20-13-18(15-6-4-3-5-7-15)17-9-8-16(22)12-19(17)20/h3-9,12,18,20,23H,10-11,13-14H2,1-2H3/t18-,20+/m0/s1/i3D,4D,5D,6D,7D	FBCSWIXKXHSYBN-LSQWYULJSA-N	50592735	CHEMBL5201983	Alpha-2C adrenergic receptor		 160								ChEMBL		10.7270/Q2P27346	35809818			Gjervig Jensen, K; Tornby Christoffersen, C; Graulund Hvenegaard, M; Didriksen, M; Jørgensen, M	H. Lundbeck A/S	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50592735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50592735&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			89287174	482603587							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51470950	Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl	InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	CEUORZQYGODEFX-UHFFFAOYSA-N	50130293	7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole	Alpha-2C adrenergic receptor		 38								ChEMBL		10.7270/Q2PR810V	34710746			Kułaga, D; Drabczyk, AK; Satała, G; Latacz, G; Rózga, K; Plażuk, D; Jaśkowska, J	Cracow University of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	9SC	7VR9,7E2Z,6A7P,7VOE,7WKZ	60795	104021727	31236	CHEMBL1112	DB01238	34	C12564	ZINC01851149	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51481383	Cl.COc1cc(OC)c(cc1OC)C1NCCc2c1[nH]c1ccc(F)cc21			50596946	CHEMBL5182943	Alpha-2C adrenergic receptor		 964								ChEMBL		10.7270/Q2ZP4B4N	35450369			Orr, MJ; Cao, AB; Wang, CT; Gaisin, A; Csakai, A; Friswold, AP; Meltzer, HY; McCorvy, JD; Scheidt, KA	Northwestern University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50596946	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50596946&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			168280485	482607798							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51505676	O=C1C2C3CCC(C3)C2C(=O)N1CC1CCCCC1CN1CCN(CC1)c1nsc2ccccc12	InChI=1S/C28H36N4O2S/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2	PQXKDMSYBGKCJA-UHFFFAOYSA-N	50606655	CHEMBL5219924	Alpha-2C adrenergic receptor		 11								ChEMBL		10.7270/Q2VQ36SJ	34311086			Kucwaj-Brysz, K; Baltrukevich, H; Czarnota, K; Handzlik, J	Jagiellonian University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50606655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50606655&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			44210114	482617506							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51504676	O[C@H]1CC[C@@H](CC1)n1cnc2n(Cc3ccccc3)c(c(-c3ccccc3)c2c1=N)-c1ccccc1	InChI=1S/C31H30N4O/c32-30-28-27(23-12-6-2-7-13-23)29(24-14-8-3-9-15-24)34(20-22-10-4-1-5-11-22)31(28)33-21-35(30)25-16-18-26(36)19-17-25/h1-15,21,25-26,32,36H,16-20H2/t25-,26-	WSMXAUJFLWRPNT-DIVCQZSQSA-N	50606398	ML-246::Metarrestin::Ml-246	Alpha-2C adrenergic receptor		 1215								ChEMBL		10.7270/Q2FN1B9R	35696646			Frankowski, KJ; Patnaik, S; Wang, C; Southall, N; Dutta, D; De, S; Li, D; Dextras, C; Lin, YH; Bryant-Connah, M; Davis, D; Wang, F; Wachsmuth, LM; Shah, P; Williams, J; Kabir, M; Zhu, E; Baljinnyam, B; Wang, A; Xu, X; Norton, J; Ferrer, M; Titus, S; Simeonov, A; Zheng, W; Mathews Griner, LA; Jadhav, A; Aubé, J; Henderson, MJ; Rudloff, U; Schoenen, FJ; Huang, S; Marugan, JJ	University of Kansas	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50606398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50606398&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			50985821	482617249							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51500738	C(Nc1ncc(-c2cccnc2)c2nncn12)c1cccc2OCCc12	InChI=1S/C19H16N6O/c1-3-14(15-6-8-26-17(15)5-1)10-21-19-22-11-16(13-4-2-7-20-9-13)18-24-23-12-25(18)19/h1-5,7,9,11-12H,6,8,10H2,(H,21,22)	VFLXVDWCZHLLLM-UHFFFAOYSA-N	291701	N-((2,3-dihydrobenzofuran-4-yl)methyl)-8-(pyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine::US11207325, Example 16::US9580437, Example 16	Alpha-2C adrenergic receptor			 3900							ChEMBL		10.7270/Q2Z323QR	35352560			Huang, Y; Sendzik, M; Zhang, J; Gao, Z; Sun, Y; Wang, L; Gu, J; Zhao, K; Yu, Z; Zhang, L; Zhang, Q; Blanz, J; Chen, Z; Dubost, V; Fang, D; Feng, L; Fu, X; Kiffe, M; Li, L; Luo, F; Luo, X; Mi, Y; Mistry, P; Pearson, D; Piaia, A; Scheufler, C; Terranova, R; Weiss, A; Zeng, J; Zhang, H; Zhang, J; Zhao, M; Dillon, MP; Jeay, S; Qi, W; Moggs, J; Pissot-Soldermann, C; Li, E; Atadja, P; Lingel, A; Oyang, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291701&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			121432827	381612002							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51500739	CS(=O)(=O)c1ccc(cc1)-c1cnc(NCc2ccco2)n2cnnc12	InChI=1S/C17H15N5O3S/c1-26(23,24)14-6-4-12(5-7-14)15-10-19-17(22-11-20-21-16(15)22)18-9-13-3-2-8-25-13/h2-8,10-11H,9H2,1H3,(H,18,19)	DYIRSNMPIZZNBK-UHFFFAOYSA-N	225230	EED226::US11013745, Compound EED226	Alpha-2C adrenergic receptor			 14000							ChEMBL		10.7270/Q2Z323QR	35352560			Huang, Y; Sendzik, M; Zhang, J; Gao, Z; Sun, Y; Wang, L; Gu, J; Zhao, K; Yu, Z; Zhang, L; Zhang, Q; Blanz, J; Chen, Z; Dubost, V; Fang, D; Feng, L; Fu, X; Kiffe, M; Li, L; Luo, F; Luo, X; Mi, Y; Mistry, P; Pearson, D; Piaia, A; Scheufler, C; Terranova, R; Weiss, A; Zeng, J; Zhang, H; Zhang, J; Zhao, M; Dillon, MP; Jeay, S; Qi, W; Moggs, J; Pissot-Soldermann, C; Li, E; Atadja, P; Lingel, A; Oyang, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=225230	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=225230&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	73K	5WUK,5GSA	123132228	336292426							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51500740	COc1cccc(F)c1CNc1ccc(-c2cnc(C)nc2C)c2nncn12	InChI=1S/C20H19FN6O/c1-12-15(9-22-13(2)25-12)14-7-8-19(27-11-24-26-20(14)27)23-10-16-17(21)5-4-6-18(16)28-3/h4-9,11,23H,10H2,1-3H3	OHVGZODROPSVRZ-UHFFFAOYSA-N	50604672	CHEMBL5178464	Alpha-2C adrenergic receptor			 8700							ChEMBL		10.7270/Q2Z323QR	35352560			Huang, Y; Sendzik, M; Zhang, J; Gao, Z; Sun, Y; Wang, L; Gu, J; Zhao, K; Yu, Z; Zhang, L; Zhang, Q; Blanz, J; Chen, Z; Dubost, V; Fang, D; Feng, L; Fu, X; Kiffe, M; Li, L; Luo, F; Luo, X; Mi, Y; Mistry, P; Pearson, D; Piaia, A; Scheufler, C; Terranova, R; Weiss, A; Zeng, J; Zhang, H; Zhang, J; Zhao, M; Dillon, MP; Jeay, S; Qi, W; Moggs, J; Pissot-Soldermann, C; Li, E; Atadja, P; Lingel, A; Oyang, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50604672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50604672&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			132256889	482615523							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51500741	C(Nc1ncc(-c2ccncc2)c2nncn12)c1cccc2OCCc12	InChI=1S/C19H16N6O/c1-2-14(15-6-9-26-17(15)3-1)10-21-19-22-11-16(13-4-7-20-8-5-13)18-24-23-12-25(18)19/h1-5,7-8,11-12H,6,9-10H2,(H,21,22)	ADDFHWGEAOKELS-UHFFFAOYSA-N	291702	N-((2,3-dihydrobenzofuran-4-yl)methyl)-8-(pyridin-4-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine::US11207325, Example 17::US9580437, Example 17	Alpha-2C adrenergic receptor			>30000							ChEMBL		10.7270/Q2Z323QR	35352560			Huang, Y; Sendzik, M; Zhang, J; Gao, Z; Sun, Y; Wang, L; Gu, J; Zhao, K; Yu, Z; Zhang, L; Zhang, Q; Blanz, J; Chen, Z; Dubost, V; Fang, D; Feng, L; Fu, X; Kiffe, M; Li, L; Luo, F; Luo, X; Mi, Y; Mistry, P; Pearson, D; Piaia, A; Scheufler, C; Terranova, R; Weiss, A; Zeng, J; Zhang, H; Zhang, J; Zhao, M; Dillon, MP; Jeay, S; Qi, W; Moggs, J; Pissot-Soldermann, C; Li, E; Atadja, P; Lingel, A; Oyang, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=291702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=291702&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			121432828	381612003							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362519	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H27F2N5OS/c1-14-3-2-6-28(13-14)16-4-7-27(8-5-16)21-26-12-19(30-21)20(29)25-11-18-17(23)9-15(22)10-24-18/h9-10,12,14,16H,2-8,11,13H2,1H3,(H,25,29)/t14-/m1/s1	MUEUIRFXUWDRNF-CQSZACIVSA-N	642917	N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 1::US20240000767, Example 152	Alpha-2C adrenergic receptor			 54.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642917	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642917&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735054	490945348							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362520	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H27F2N5OS/c1-14-3-2-6-28(13-14)16-4-7-27(8-5-16)21-26-12-19(30-21)20(29)25-11-18-17(23)9-15(22)10-24-18/h9-10,12,14,16H,2-8,11,13H2,1H3,(H,25,29)/t14-/m1/s1	MUEUIRFXUWDRNF-CQSZACIVSA-N	642917	N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 1::US20240000767, Example 152	Alpha-2C adrenergic receptor		 24.0								US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642917	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642917&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735054	490945348							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362521	COCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5O2S/c1-31-14-15-3-2-6-29(13-15)17-4-7-28(8-5-17)22-27-12-20(32-22)21(30)26-11-19-18(24)9-16(23)10-25-19/h9-10,12,15,17H,2-8,11,13-14H2,1H3,(H,26,30)	ZGHRVPCMUPGYQM-UHFFFAOYSA-N	642921	US20240000767, Example 100::US20240000767, Example 48::US20240000767, Example 99::ent-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-(methoxymethyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide (enantiomer 2)	Alpha-2C adrenergic receptor			 5.00							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642921	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642921&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735052	490945349							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362522	COCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5O2S/c1-31-14-15-3-2-6-29(13-15)17-4-7-28(8-5-17)22-27-12-20(32-22)21(30)26-11-19-18(24)9-16(23)10-25-19/h9-10,12,15,17H,2-8,11,13-14H2,1H3,(H,26,30)	ZGHRVPCMUPGYQM-UHFFFAOYSA-N	642921	US20240000767, Example 100::US20240000767, Example 48::US20240000767, Example 99::ent-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-(methoxymethyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide (enantiomer 2)	Alpha-2C adrenergic receptor		 2.00								US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642921	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642921&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735052	490945349							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362523	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H27F2N5OS/c1-14-3-2-6-28(13-14)16-4-7-27(8-5-16)21-26-12-19(30-21)20(29)25-11-18-17(23)9-15(22)10-24-18/h9-10,12,14,16H,2-8,11,13H2,1H3,(H,25,29)/t14-/m1/s1	MUEUIRFXUWDRNF-CQSZACIVSA-N	642917	N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 1::US20240000767, Example 152	Alpha-2C adrenergic receptor			 121							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642917	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642917&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735054	490945348							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362524	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCc3ccccc3C2)c(F)c1	InChI=1S/C24H25F2N5OS/c25-18-11-20(26)21(27-12-18)13-28-23(32)22-14-29-24(33-22)30-9-6-19(7-10-30)31-8-5-16-3-1-2-4-17(16)15-31/h1-4,11-12,14,19H,5-10,13,15H2,(H,28,32)	JLUACQZQDHMKGC-UHFFFAOYSA-N	642924	N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[4-(3,4-dihydroisoquinolin-2(1H)-yl)piperidin-1-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 2	Alpha-2C adrenergic receptor			 5.20							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642924	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642924&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735205	490945350							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362525	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(CC3CC3)C2)c(F)c1	InChI=1S/C24H31F2N5OS/c25-18-11-20(26)21(27-12-18)13-28-23(32)22-14-29-24(33-22)30-8-5-19(6-9-30)31-7-1-2-17(15-31)10-16-3-4-16/h11-12,14,16-17,19H,1-10,13,15H2,(H,28,32)	SJYFHRUFDMNIGL-UHFFFAOYSA-N	642929	2-[3-(Cyclopropylmethyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide (racemate)::US20240000767, Example 3	Alpha-2C adrenergic receptor			 2.90							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642929	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642929&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735081	490945351							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362526	FC(F)C1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H25F4N5OS/c22-14-8-16(23)17(26-9-14)10-27-20(31)18-11-28-21(32-18)29-6-3-15(4-7-29)30-5-1-2-13(12-30)19(24)25/h8-9,11,13,15,19H,1-7,10,12H2,(H,27,31)	VPWHKINYNYPEHV-UHFFFAOYSA-N	642930	US20240000767, Example 4	Alpha-2C adrenergic receptor			 169							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642930	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642930&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735100	490945352							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362527	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)C(F)(F)F)c(F)c1	InChI=1S/C21H24F5N5OS/c22-14-8-16(23)17(27-9-14)10-28-19(32)18-11-29-20(33-18)30-6-3-15(4-7-30)31-5-1-2-13(12-31)21(24,25)26/h8-9,11,13,15H,1-7,10,12H2,(H,28,32)	HQKVTLUZNWDMMA-UHFFFAOYSA-N	642931	US20240000767, Example 5	Alpha-2C adrenergic receptor			 335							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642931&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735192	490945353							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362528	FCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H26F3N5OS/c22-9-14-2-1-5-29(13-14)16-3-6-28(7-4-16)21-27-12-19(31-21)20(30)26-11-18-17(24)8-15(23)10-25-18/h8,10,12,14,16H,1-7,9,11,13H2,(H,26,30)	LJBFXAUXXNXJDB-UHFFFAOYSA-N	642932	US20240000767, Example 6	Alpha-2C adrenergic receptor			 335							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642932	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642932&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735098	490945354							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362529	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CC(F)(F)C2)c(F)c1	InChI=1S/C25H31F4N5O2S/c26-17-8-20(27)21(30-11-17)12-31-23(35)22-13-32-24(37-22)33-6-3-18(4-7-33)34-5-1-2-19(14-34)36-15-16-9-25(28,29)10-16/h8,11,13,16,18-19H,1-7,9-10,12,14-15H2,(H,31,35)	CWQBAECTXGXCCG-UHFFFAOYSA-N	642933	US20240000767, Example 44::US20240000767, Example 7	Alpha-2C adrenergic receptor			 49.6							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642933	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642933&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156734992	490945355							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362530	C[C@@H]1CCCN(C1)C1CCN(CC1)c1nc(C)c(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5OS/c1-14-4-3-7-29(13-14)17-5-8-28(9-6-17)22-27-15(2)20(31-22)21(30)26-12-19-18(24)10-16(23)11-25-19/h10-11,14,17H,3-9,12-13H2,1-2H3,(H,26,30)/t14-/m1/s1	DMRJFGWSEDSVGP-CQSZACIVSA-N	642934	US20240000767, Example 8	Alpha-2C adrenergic receptor			 591							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642934	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642934&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435045	490945356							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362531	C[C@@H]1CCCN(C1)C1CCN(CC1)c1nc(C(=O)NCc2ncc(F)cc2F)c(C)s1	InChI=1S/C22H29F2N5OS/c1-14-4-3-7-29(13-14)17-5-8-28(9-6-17)22-27-20(15(2)31-22)21(30)26-12-19-18(24)10-16(23)11-25-19/h10-11,14,17H,3-9,12-13H2,1-2H3,(H,26,30)/t14-/m1/s1	BCECKXJRRDBNOR-CQSZACIVSA-N	642935	US20240000767, Example 9	Alpha-2C adrenergic receptor			 170							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642935	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642935&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166933434	490945357							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362532	C[C@@H]1CCCN(C1)C1CCN(CC1)c1nc(cs1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H27F2N5OS/c1-14-3-2-6-28(12-14)16-4-7-27(8-5-16)21-26-19(13-30-21)20(29)25-11-18-17(23)9-15(22)10-24-18/h9-10,13-14,16H,2-8,11-12H2,1H3,(H,25,29)/t14-/m1/s1	FDEUCGVWKMJJFT-CQSZACIVSA-N	642936	US20240000767, Example 10	Alpha-2C adrenergic receptor			 21.4							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642936	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642936&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166933455	490945358							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362533	C[C@@H]1CCCN(C1)C1CCN(CC1)c1nc(c(s1)C(=O)NCc1ncc(F)cc1F)C(F)(F)F	InChI=1S/C22H26F5N5OS/c1-13-3-2-6-32(12-13)15-4-7-31(8-5-15)21-30-19(22(25,26)27)18(34-21)20(33)29-11-17-16(24)9-14(23)10-28-17/h9-10,13,15H,2-8,11-12H2,1H3,(H,29,33)/t13-/m1/s1	CAPQJLICKWEIEH-CYBMUJFWSA-N	642937	US20240000767, Example 11	Alpha-2C adrenergic receptor			 140							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642937	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642937&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435000	490945359							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362534	CCc1sc(nc1C(=O)NCc1ncc(F)cc1F)N1CCC(CC1)N1CCC[C@@H](C)C1	InChI=1S/C23H31F2N5OS/c1-3-20-21(22(31)27-13-19-18(25)11-16(24)12-26-19)28-23(32-20)29-9-6-17(7-10-29)30-8-4-5-15(2)14-30/h11-12,15,17H,3-10,13-14H2,1-2H3,(H,27,31)/t15-/m1/s1	LBYMOALJPIOZEP-OAHLLOKOSA-N	642938	US20240000767, Example 12	Alpha-2C adrenergic receptor			 107							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642938	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642938&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435010	490945360							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362535	C[C@@H]1CCCN(C1)C1CCN(CC1)c1nc(co1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H27F2N5O2/c1-14-3-2-6-28(12-14)16-4-7-27(8-5-16)21-26-19(13-30-21)20(29)25-11-18-17(23)9-15(22)10-24-18/h9-10,13-14,16H,2-8,11-12H2,1H3,(H,25,29)/t14-/m1/s1	HGMHACPFMGZVJO-CQSZACIVSA-N	642939	US20240000767, Example 13	Alpha-2C adrenergic receptor			 209							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642939	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642939&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162434986	490945361							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362536	C[C@@H]1CCCN(C1)C1CCN(CC1)c1nc(C(=O)NCc2ncc(F)cc2F)c(C)o1	InChI=1S/C22H29F2N5O2/c1-14-4-3-7-29(13-14)17-5-8-28(9-6-17)22-27-20(15(2)31-22)21(30)26-12-19-18(24)10-16(23)11-25-19/h10-11,14,17H,3-9,12-13H2,1-2H3,(H,26,30)/t14-/m1/s1	GMSHNYLBYUALQW-CQSZACIVSA-N	642940	US20240000767, Example 14	Alpha-2C adrenergic receptor			 211							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642940	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642940&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435020	490945362							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362537	CO[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H27F2N5O2S/c1-30-16-3-2-6-28(13-16)15-4-7-27(8-5-15)21-26-12-19(31-21)20(29)25-11-18-17(23)9-14(22)10-24-18/h9-10,12,15-16H,2-8,11,13H2,1H3,(H,25,29)/t16-/m1/s1	ACYWORCQNDVLGO-MRXNPFEDSA-N	642941	N-[(3,5-difluoropyridin-2-yl)methyl]-2-[(3R)-3-methoxy[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 15	Alpha-2C adrenergic receptor			 1850							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642941	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642941&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735142	490945363							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362538	FC(F)OC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H25F4N5O2S/c22-13-8-16(23)17(26-9-13)10-27-19(31)18-11-28-21(33-18)29-6-3-14(4-7-29)30-5-1-2-15(12-30)32-20(24)25/h8-9,11,14-15,20H,1-7,10,12H2,(H,27,31)	DUGIRRRXICEDDA-UHFFFAOYSA-N	642942	2-[3-(Difluoromethoxy)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide (racemate)::US20240000767, Example 16	Alpha-2C adrenergic receptor			 2000							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642942	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642942&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735012	490945364							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362539	CCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5OS/c1-2-15-4-3-7-29(14-15)17-5-8-28(9-6-17)22-27-13-20(31-22)21(30)26-12-19-18(24)10-16(23)11-25-19/h10-11,13,15,17H,2-9,12,14H2,1H3,(H,26,30)	LGIJTNSTRXQVAY-UHFFFAOYSA-N	642943	N-[(3,5-Difluoropyridin-2-yl)methyl]-2-(3-ethyl[1,4&#8242;-bipiperidin]-1&#8242;-yl)-1,3-thiazole-5-carboxamide (racemate)::US20240000767, Example 17	Alpha-2C adrenergic receptor			 26.5							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642943	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642943&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735136	490945365							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362540	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cc(ccn1)C(F)(F)F	InChI=1S/C22H28F3N5OS/c1-15-3-2-8-30(14-15)18-5-9-29(10-6-18)21-28-13-19(32-21)20(31)27-12-17-11-16(4-7-26-17)22(23,24)25/h4,7,11,13,15,18H,2-3,5-6,8-10,12,14H2,1H3,(H,27,31)/t15-/m1/s1	TZYQMXYEERLMFR-OAHLLOKOSA-N	642944	2-[(3R)-3-Methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-{[4-(trifluoromethyl)pyridin-2-yl]methyl}-1,3-thiazole-5-carboxamide::US20240000767, Example 18	Alpha-2C adrenergic receptor			 6800							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642944	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642944&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735111	490945366							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362541	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cccc(c1)C(F)(F)F	InChI=1S/C23H29F3N4OS/c1-16-4-3-9-30(15-16)19-7-10-29(11-8-19)22-28-14-20(32-22)21(31)27-13-17-5-2-6-18(12-17)23(24,25)26/h2,5-6,12,14,16,19H,3-4,7-11,13,15H2,1H3,(H,27,31)/t16-/m1/s1	HSHITHPDUBUXHN-MRXNPFEDSA-N	642945	2-[(3R)-3-Methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[3-(trifluoromethyl)benzyl]-1,3-thiazole-5-carboxamide::US20240000767, Example 19	Alpha-2C adrenergic receptor			 690							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642945	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642945&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735013	490945367							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362542	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncccc1F	InChI=1S/C21H28FN5OS/c1-15-4-3-9-27(14-15)16-6-10-26(11-7-16)21-25-13-19(29-21)20(28)24-12-18-17(22)5-2-8-23-18/h2,5,8,13,15-16H,3-4,6-7,9-12,14H2,1H3,(H,24,28)/t15-/m1/s1	ZURZCBXWPLILEE-OAHLLOKOSA-N	642946	N-[(3-Fluoropyridin-2-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 20	Alpha-2C adrenergic receptor			 110							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642946	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642946&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735110	490945368							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362543	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cc(Cl)ccc1F	InChI=1S/C22H28ClFN4OS/c1-15-3-2-8-28(14-15)18-6-9-27(10-7-18)22-26-13-20(30-22)21(29)25-12-16-11-17(23)4-5-19(16)24/h4-5,11,13,15,18H,2-3,6-10,12,14H2,1H3,(H,25,29)/t15-/m1/s1	HIDWMBYGJAWHPJ-OAHLLOKOSA-N	642947	N-(5-Chloro-2-fluorobenzyl)-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 21	Alpha-2C adrenergic receptor			 7.20							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642947	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642947&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735028	490945369							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362544	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccc(cc1)C(F)(F)F	InChI=1S/C23H29F3N4OS/c1-16-3-2-10-30(15-16)19-8-11-29(12-9-19)22-28-14-20(32-22)21(31)27-13-17-4-6-18(7-5-17)23(24,25)26/h4-7,14,16,19H,2-3,8-13,15H2,1H3,(H,27,31)/t16-/m1/s1	NVWNLAWPUXHHSF-MRXNPFEDSA-N	642948	2-[(3R)-3-Methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[4-(trifluoromethyl)benzyl]-1,3-thiazole-5-carboxamide::US20240000767, Example 22	Alpha-2C adrenergic receptor			 640							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642948	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642948&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735036	490945370							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362545	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(Cl)cc1F	InChI=1S/C21H27ClFN5OS/c1-14-3-2-6-28(13-14)16-4-7-27(8-5-16)21-26-12-19(30-21)20(29)25-11-18-17(23)9-15(22)10-24-18/h9-10,12,14,16H,2-8,11,13H2,1H3,(H,25,29)/t14-/m1/s1	JXHPUNZMLGSEOI-CQSZACIVSA-N	642949	US20240000767, Example 23	Alpha-2C adrenergic receptor			 17.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642949	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642949&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435040	490945371							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362546	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncccc1C	InChI=1S/C22H31N5OS/c1-16-5-4-10-27(15-16)18-7-11-26(12-8-18)22-25-14-20(29-22)21(28)24-13-19-17(2)6-3-9-23-19/h3,6,9,14,16,18H,4-5,7-8,10-13,15H2,1-2H3,(H,24,28)/t16-/m1/s1	ISTGZUIALMAMEN-MRXNPFEDSA-N	642950	US20240000767, Example 24	Alpha-2C adrenergic receptor			 1060							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642950	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642950&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435049	490945372							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362547	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cc(C)ccn1	InChI=1S/C22H31N5OS/c1-16-5-8-23-18(12-16)13-24-21(28)20-14-25-22(29-20)26-10-6-19(7-11-26)27-9-3-4-17(2)15-27/h5,8,12,14,17,19H,3-4,6-7,9-11,13,15H2,1-2H3,(H,24,28)/t17-/m1/s1	IBJNTURIRJPQNJ-QGZVFWFLSA-N	642951	US20240000767, Example 25	Alpha-2C adrenergic receptor			 2400							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642951	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642951&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162434987	490945373							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362548	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncccc1Cl	InChI=1S/C21H28ClN5OS/c1-15-4-3-9-27(14-15)16-6-10-26(11-7-16)21-25-13-19(29-21)20(28)24-12-18-17(22)5-2-8-23-18/h2,5,8,13,15-16H,3-4,6-7,9-12,14H2,1H3,(H,24,28)/t15-/m1/s1	AOAFEUDHGYMTNZ-OAHLLOKOSA-N	642952	US20240000767, Example 26	Alpha-2C adrenergic receptor			 280							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642952	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642952&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435027	490945374							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362549	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)N(C)Cc1ncccc1F	InChI=1S/C22H30FN5OS/c1-16-5-4-10-28(14-16)17-7-11-27(12-8-17)22-25-13-20(30-22)21(29)26(2)15-19-18(23)6-3-9-24-19/h3,6,9,13,16-17H,4-5,7-8,10-12,14-15H2,1-2H3/t16-/m1/s1	SBXDDPLHZCLGKE-MRXNPFEDSA-N	642953	US20240000767, Example 27	Alpha-2C adrenergic receptor			 310							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642953	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642953&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435034	490945375							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362550	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cccc(n1)C(F)(F)F	InChI=1S/C22H28F3N5OS/c1-15-4-3-9-30(14-15)17-7-10-29(11-8-17)21-27-13-18(32-21)20(31)26-12-16-5-2-6-19(28-16)22(23,24)25/h2,5-6,13,15,17H,3-4,7-12,14H2,1H3,(H,26,31)/t15-/m1/s1	XDNRSPSDBMQREB-OAHLLOKOSA-N	642954	2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-{[6- (trifluoromethyl)pyridin-2-yl]methyl}-1,3-thiazole-5-carboxamide::US20240000767, Example 28	Alpha-2C adrenergic receptor			 890							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642954	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642954&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435005	490945376							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362551	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccc(Cl)cn1	InChI=1S/C21H28ClN5OS/c1-15-3-2-8-27(14-15)18-6-9-26(10-7-18)21-25-13-19(29-21)20(28)24-12-17-5-4-16(22)11-23-17/h4-5,11,13,15,18H,2-3,6-10,12,14H2,1H3,(H,24,28)/t15-/m1/s1	URPVBKRLWXQZOY-OAHLLOKOSA-N	642955	2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[(5-chloropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide::US20240000767, Example 29	Alpha-2C adrenergic receptor			 96.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642955	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642955&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435030	490945377							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362552	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1Cl	InChI=1S/C21H27ClFN5OS/c1-14-3-2-6-28(13-14)16-4-7-27(8-5-16)21-26-12-19(30-21)20(29)25-11-18-17(22)9-15(23)10-24-18/h9-10,12,14,16H,2-8,11,13H2,1H3,(H,25,29)/t14-/m1/s1	GZISKYDRVKZMMR-CQSZACIVSA-N	642956	2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[(3-chloro-5-fluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide::US20240000767, Example 31	Alpha-2C adrenergic receptor			 89.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642956	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642956&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162434993	490945378							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362553	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cccc(OC(F)(F)F)n1	InChI=1S/C22H28F3N5O2S/c1-15-4-3-9-30(14-15)17-7-10-29(11-8-17)21-27-13-18(33-21)20(31)26-12-16-5-2-6-19(28-16)32-22(23,24)25/h2,5-6,13,15,17H,3-4,7-12,14H2,1H3,(H,26,31)/t15-/m1/s1	ZLYXFPUJTQIMFP-OAHLLOKOSA-N	642957	US20240000767, Example 32	Alpha-2C adrenergic receptor			 640							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642957&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435022	490945379							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362554	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccc(Cl)cc1	InChI=1S/C22H29ClN4OS/c1-16-3-2-10-27(15-16)19-8-11-26(12-9-19)22-25-14-20(29-22)21(28)24-13-17-4-6-18(23)7-5-17/h4-7,14,16,19H,2-3,8-13,15H2,1H3,(H,24,28)/t16-/m1/s1	AOUQACQILRMDBX-MRXNPFEDSA-N	642958	US20240000767, Example 33	Alpha-2C adrenergic receptor			 15.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642958	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642958&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435007	490945380							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362555	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cc(F)ccc1Cl	InChI=1S/C22H28ClFN4OS/c1-15-3-2-8-28(14-15)18-6-9-27(10-7-18)22-26-13-20(30-22)21(29)25-12-16-11-17(24)4-5-19(16)23/h4-5,11,13,15,18H,2-3,6-10,12,14H2,1H3,(H,25,29)/t15-/m1/s1	TVAPZDPIMJKMSH-OAHLLOKOSA-N	642959	US20240000767, Example 34	Alpha-2C adrenergic receptor			 640							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642959	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642959&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162434997	490945381							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362556	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccc(C)cc1	InChI=1S/C23H32N4OS/c1-17-5-7-19(8-6-17)14-24-22(28)21-15-25-23(29-21)26-12-9-20(10-13-26)27-11-3-4-18(2)16-27/h5-8,15,18,20H,3-4,9-14,16H2,1-2H3,(H,24,28)/t18-/m1/s1	WNISPQITENBJQS-GOSISDBHSA-N	642960	US20240000767, Example 35	Alpha-2C adrenergic receptor			 1000							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642960	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642960&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162434990	490945382							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362557	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cccc(C)c1	InChI=1S/C23H32N4OS/c1-17-5-3-7-19(13-17)14-24-22(28)21-15-25-23(29-21)26-11-8-20(9-12-26)27-10-4-6-18(2)16-27/h3,5,7,13,15,18,20H,4,6,8-12,14,16H2,1-2H3,(H,24,28)/t18-/m1/s1	YCDYQJXWVJUZKL-GOSISDBHSA-N	642961	US20240000767, Example 36	Alpha-2C adrenergic receptor			 190							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642961	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642961&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435023	490945383							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362558	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccccc1C	InChI=1S/C23H32N4OS/c1-17-6-5-11-27(16-17)20-9-12-26(13-10-20)23-25-15-21(29-23)22(28)24-14-19-8-4-3-7-18(19)2/h3-4,7-8,15,17,20H,5-6,9-14,16H2,1-2H3,(H,24,28)/t17-/m1/s1	HQAOAAJOEAMTMU-QGZVFWFLSA-N	642962	US20240000767, Example 37	Alpha-2C adrenergic receptor			 200							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642962	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642962&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435028	490945384							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362559	FC(F)[C@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H25F4N5OS/c22-14-8-16(23)17(26-9-14)10-27-20(31)18-11-28-21(32-18)29-6-3-15(4-7-29)30-5-1-2-13(12-30)19(24)25/h8-9,11,13,15,19H,1-7,10,12H2,(H,27,31)/t13-/m0/s1	VPWHKINYNYPEHV-ZDUSSCGKSA-N	642963	2-[3-(Difluoromethyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide (enantiomers 1 and 2)::US20240000767, Example 38	Alpha-2C adrenergic receptor			 2340							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642963	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642963&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735101	490945385							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362560	FC(F)[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H25F4N5OS/c22-14-8-16(23)17(26-9-14)10-27-20(31)18-11-28-21(32-18)29-6-3-15(4-7-29)30-5-1-2-13(12-30)19(24)25/h8-9,11,13,15,19H,1-7,10,12H2,(H,27,31)/t13-/m1/s1	VPWHKINYNYPEHV-CYBMUJFWSA-N	642964	US20240000767, Example 39	Alpha-2C adrenergic receptor			 135							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642964&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735023	490945386							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362561	FC[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H26F3N5OS/c22-9-14-2-1-5-29(13-14)16-3-6-28(7-4-16)21-27-12-19(31-21)20(30)26-11-18-17(24)8-15(23)10-25-18/h8,10,12,14,16H,1-7,9,11,13H2,(H,26,30)/t14-/m0/s1	LJBFXAUXXNXJDB-AWEZNQCLSA-N	642965	US20240000767, Example 41	Alpha-2C adrenergic receptor			 243							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642965	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642965&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735080	490945387							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362562	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCC[C@H](C2)C(F)(F)F)c(F)c1	InChI=1S/C21H24F5N5OS/c22-14-8-16(23)17(27-9-14)10-28-19(32)18-11-29-20(33-18)30-6-3-15(4-7-30)31-5-1-2-13(12-31)21(24,25)26/h8-9,11,13,15H,1-7,10,12H2,(H,28,32)/t13-/m1/s1	HQKVTLUZNWDMMA-CYBMUJFWSA-N	642966	US20240000767, Example 43	Alpha-2C adrenergic receptor			 26.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642966	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642966&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735035	490945388							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362563	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CC(F)(F)C2)c(F)c1	InChI=1S/C25H31F4N5O2S/c26-17-8-20(27)21(30-11-17)12-31-23(35)22-13-32-24(37-22)33-6-3-18(4-7-33)34-5-1-2-19(14-34)36-15-16-9-25(28,29)10-16/h8,11,13,16,18-19H,1-7,9-10,12,14-15H2,(H,31,35)	CWQBAECTXGXCCG-UHFFFAOYSA-N	642933	US20240000767, Example 44::US20240000767, Example 7	Alpha-2C adrenergic receptor			 41.2							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642933	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642933&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156734992	490945355							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362564	CC(NC(=O)c1cnc(s1)N1CCC(CC1)N1CCC[C@H](C)C1)c1cc(F)ccc1F	InChI=1S/C23H30F2N4OS/c1-15-4-3-9-29(14-15)18-7-10-28(11-8-18)23-26-13-21(31-23)22(30)27-16(2)19-12-17(24)5-6-20(19)25/h5-6,12-13,15-16,18H,3-4,7-11,14H2,1-2H3,(H,27,30)/t15-,16?/m0/s1	BZWXSCOJOIAPOU-VYRBHSGPSA-N	642968	N-[1-(2,5-Difluorophenyl)ethyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide (diastereomers 1 and 2)::US20240000767, Example 46	Alpha-2C adrenergic receptor			 8.30							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642968	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642968&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			171034127	490945389							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362565	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cc(F)ccc1F	InChI=1S/C22H28F2N4OS/c1-15-3-2-8-28(14-15)18-6-9-27(10-7-18)22-26-13-20(30-22)21(29)25-12-16-11-17(23)4-5-19(16)24/h4-5,11,13,15,18H,2-3,6-10,12,14H2,1H3,(H,25,29)/t15-/m1/s1	YBYQOZCFIZVCBY-OAHLLOKOSA-N	642969	US20240000767, Example 47::US20240000767, Example 81	Alpha-2C adrenergic receptor			 25.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642969	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642969&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735213	490945390							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362566	COCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5O2S/c1-31-14-15-3-2-6-29(13-15)17-4-7-28(8-5-17)22-27-12-20(32-22)21(30)26-11-19-18(24)9-16(23)10-25-19/h9-10,12,15,17H,2-8,11,13-14H2,1H3,(H,26,30)	ZGHRVPCMUPGYQM-UHFFFAOYSA-N	642921	US20240000767, Example 100::US20240000767, Example 48::US20240000767, Example 99::ent-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-(methoxymethyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide (enantiomer 2)	Alpha-2C adrenergic receptor			 17.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642921	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642921&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735052	490945349							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362567	C[C@@H]1CCCN(C1)C1CCN(CC1)c1noc(n1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C20H26F2N6O2/c1-13-3-2-6-28(12-13)15-4-7-27(8-5-15)20-25-19(30-26-20)18(29)24-11-17-16(22)9-14(21)10-23-17/h9-10,13,15H,2-8,11-12H2,1H3,(H,24,29)/t13-/m1/s1	VMFHHJCIVLAPFA-CYBMUJFWSA-N	642971	N-[(3,5-Difluoropyridin-2-yl)methyl]-3-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,2,4-oxadiazole-5-carboxamide::US20240000767, Example 49	Alpha-2C adrenergic receptor			 56.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642971	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642971&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735225	490945391							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362568	C[C@@H]1CCCN(C1)C1CCN(CC1F)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H26F3N5OS/c1-13-3-2-5-28(11-13)18-4-6-29(12-16(18)24)21-27-10-19(31-21)20(30)26-9-17-15(23)7-14(22)8-25-17/h7-8,10,13,16,18H,2-6,9,11-12H2,1H3,(H,26,30)/t13-,16?,18?/m1/s1	KTHHJXFIHKRDIP-IMUUDWKMSA-N	642972	US20240000767, Example 50::US20240000767, Example 51::US20240000767, Example 52::diamix-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3&#8242;-fluoro-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 73.5							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642972&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735008	490945392							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362569	C[C@@H]1CCCN(C1)C1CCN(CC1F)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H26F3N5OS/c1-13-3-2-5-28(11-13)18-4-6-29(12-16(18)24)21-27-10-19(31-21)20(30)26-9-17-15(23)7-14(22)8-25-17/h7-8,10,13,16,18H,2-6,9,11-12H2,1H3,(H,26,30)/t13-,16?,18?/m1/s1	KTHHJXFIHKRDIP-IMUUDWKMSA-N	642972	US20240000767, Example 50::US20240000767, Example 51::US20240000767, Example 52::diamix-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3&#8242;-fluoro-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 150							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642972&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735008	490945392							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362570	C[C@@H]1CCCN(C1)C1CCN(CC1F)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H26F3N5OS/c1-13-3-2-5-28(11-13)18-4-6-29(12-16(18)24)21-27-10-19(31-21)20(30)26-9-17-15(23)7-14(22)8-25-17/h7-8,10,13,16,18H,2-6,9,11-12H2,1H3,(H,26,30)/t13-,16?,18?/m1/s1	KTHHJXFIHKRDIP-IMUUDWKMSA-N	642972	US20240000767, Example 50::US20240000767, Example 51::US20240000767, Example 52::diamix-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3&#8242;-fluoro-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 6.70							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642972&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735008	490945392							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362571	CC1CCCN(CC1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5OS/c1-15-3-2-7-28(8-4-15)17-5-9-29(10-6-17)22-27-14-20(31-22)21(30)26-13-19-18(24)11-16(23)12-25-19/h11-12,14-15,17H,2-10,13H2,1H3,(H,26,30)	WIZHCLUYDUKIJF-UHFFFAOYSA-N	642975	US20240000767, Example 104::US20240000767, Example 105::US20240000767, Example 53::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[4-(4-methylazepan-1-yl)piperidin-1-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 110							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642975&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735026	490945393							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362572	CC1CCCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5OS/c1-15-4-2-3-7-29(14-15)17-5-8-28(9-6-17)22-27-13-20(31-22)21(30)26-12-19-18(24)10-16(23)11-25-19/h10-11,13,15,17H,2-9,12,14H2,1H3,(H,26,30)	ZATNZCSUYFGJIF-UHFFFAOYSA-N	642976	US20240000767, Example 54::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[4-(3-methylazepan-1-yl)piperidin-1-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 230							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642976	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642976&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735117	490945394							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362573	CC(NC(=O)c1cnc(s1)N1CCC(CC1)N1CCC[C@@H](C)C1)c1ncc(F)cc1F	InChI=1S/C22H29F2N5OS/c1-14-4-3-7-29(13-14)17-5-8-28(9-6-17)22-26-12-19(31-22)21(30)27-15(2)20-18(24)10-16(23)11-25-20/h10-12,14-15,17H,3-9,13H2,1-2H3,(H,27,30)/t14-,15?/m1/s1	RNXTVMVVEWBMQV-GICMACPYSA-N	642977	US20240000767, Example 55::diamix-N-[1-(3,5-Difluoropyridin-2-yl)ethyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 150							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642977	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642977&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735082	490945395							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362574	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(Cl)s1	InChI=1S/C19H26ClN5OS2/c1-13-3-2-6-25(12-13)14-4-7-24(8-5-14)19-23-9-15(27-19)18(26)22-11-17-21-10-16(20)28-17/h9-10,13-14H,2-8,11-12H2,1H3,(H,22,26)/t13-/m1/s1	BBDOJERGYJRGHL-CYBMUJFWSA-N	642978	N-[(5-Chloro-1,3-thiazol-2-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 56	Alpha-2C adrenergic receptor			 240							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642978	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642978&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735227	490945396							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362575	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccc(F)s1	InChI=1S/C20H27FN4OS2/c1-14-3-2-8-25(13-14)15-6-9-24(10-7-15)20-23-12-17(28-20)19(26)22-11-16-4-5-18(21)27-16/h4-5,12,14-15H,2-3,6-11,13H2,1H3,(H,22,26)/t14-/m1/s1	YSVTUGUVDPKHGU-CQSZACIVSA-N	642979	N-[(5-Fluoro-2-thienyl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 57	Alpha-2C adrenergic receptor			 830							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642979&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735011	490945397							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362576	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccncc1	InChI=1S/C21H29N5OS/c1-16-3-2-10-26(15-16)18-6-11-25(12-7-18)21-24-14-19(28-21)20(27)23-13-17-4-8-22-9-5-17/h4-5,8-9,14,16,18H,2-3,6-7,10-13,15H2,1H3,(H,23,27)/t16-/m1/s1	GTILCGJSYNYTQF-MRXNPFEDSA-N	642980	2-[(3R)-3-Methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-(pyridin-4-ylmethyl)-1,3-thiazole-5-carboxamide::US20240000767, Example 58	Alpha-2C adrenergic receptor			 870							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642980	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642980&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735079	490945398							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362577	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COCC(F)(F)F)C2)c(F)c1	InChI=1S/C23H28F5N5O2S/c24-16-8-18(25)19(29-9-16)10-30-21(34)20-11-31-22(36-20)32-6-3-17(4-7-32)33-5-1-2-15(12-33)13-35-14-23(26,27)28/h8-9,11,15,17H,1-7,10,12-14H2,(H,30,34)	MGVMZZPBXYYHDX-UHFFFAOYSA-N	642981	US20240000767, Example 106::US20240000767, Example 107::US20240000767, Example 59::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-{3-[(2,2,2-trifluoroethoxy)methyl][1,4&#8242;-bipiperidin]-1&#8242;-yl}-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 11.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642981	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642981&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735224	490945399							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362578	FCC1(COCC2CCCN(C2)C2CCN(CC2)c2ncc(s2)C(=O)NCc2ncc(F)cc2F)CC1	InChI=1S/C26H34F3N5O2S/c27-16-26(5-6-26)17-36-15-18-2-1-7-34(14-18)20-3-8-33(9-4-20)25-32-13-23(37-25)24(35)31-12-22-21(29)10-19(28)11-30-22/h10-11,13,18,20H,1-9,12,14-17H2,(H,31,35)	OQEMITLRNBOFFA-UHFFFAOYSA-N	642982	US20240000767, Example 60::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-({[1-(fluoromethyl)cyclopropyl]methoxy}methyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 74.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642982	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642982&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735056	490945400							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362579	FC(F)C1(COCC2CCCN(C2)C2CCN(CC2)c2ncc(s2)C(=O)NCc2ncc(F)cc2F)CC1	InChI=1S/C26H33F4N5O2S/c27-18-10-20(28)21(31-11-18)12-32-23(36)22-13-33-25(38-22)34-8-3-19(4-9-34)35-7-1-2-17(14-35)15-37-16-26(5-6-26)24(29)30/h10-11,13,17,19,24H,1-9,12,14-16H2,(H,32,36)	CEZIHEKGUUCKPT-UHFFFAOYSA-N	642983	US20240000767, Example 61::rac-2-[3-({[1-(Difluoromethyl)cyclopropyl]methoxy}methyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 87.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642983	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642983&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735093	490945401							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362580	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COCC3(CC3)C(F)(F)F)C2)c(F)c1	InChI=1S/C26H32F5N5O2S/c27-18-10-20(28)21(32-11-18)12-33-23(37)22-13-34-24(39-22)35-8-3-19(4-9-35)36-7-1-2-17(14-36)15-38-16-25(5-6-25)26(29,30)31/h10-11,13,17,19H,1-9,12,14-16H2,(H,33,37)	YWRZKCUPSMDAKX-UHFFFAOYSA-N	642984	US20240000767, Example 62::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-({[1-(trifluoromethyl)cyclopropyl]methoxy}methyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 130							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642984	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642984&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735160	490945402							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362581	CC1(C)CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5OS/c1-22(2)6-3-7-29(14-22)16-4-8-28(9-5-16)21-27-13-19(31-21)20(30)26-12-18-17(24)10-15(23)11-25-18/h10-11,13,16H,3-9,12,14H2,1-2H3,(H,26,30)	GNJCQBOCMNCCGU-UHFFFAOYSA-N	642985	N-[(3,5-Difluoropyridin-2-yl)methyl]-2-(3,3-dimethyl[1,4&#8242;-bipiperidin]-1&#8242;-yl)-1,3-thiazole-5-carboxamide::US20240000767, Example 63	Alpha-2C adrenergic receptor			 570							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642985	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642985&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735208	490945403							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362582	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC3(CC3)C2)c(F)c1	InChI=1S/C22H27F2N5OS/c23-15-10-17(24)18(25-11-15)12-26-20(30)19-13-27-21(31-19)28-8-2-16(3-9-28)29-7-1-4-22(14-29)5-6-22/h10-11,13,16H,1-9,12,14H2,(H,26,30)	WMSFMRUUAJDNIZ-UHFFFAOYSA-N	642986	2-[4-(5-Azaspiro[2.5]octan-5-yl)piperidin-1-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide::US20240000767, Example 64	Alpha-2C adrenergic receptor			 1.40							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642986	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642986&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735059	490945404							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362583	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC3(CC3(F)F)C2)c(F)c1	InChI=1S/C22H25F4N5OS/c23-14-8-16(24)17(27-9-14)10-28-19(32)18-11-29-20(33-18)30-6-2-15(3-7-30)31-5-1-4-21(13-31)12-22(21,25)26/h8-9,11,15H,1-7,10,12-13H2,(H,28,32)	GEIIJNRSUPZTGW-UHFFFAOYSA-N	642987	US20240000767, Example 131::US20240000767, Example 132::US20240000767, Example 65::rac-2-[4-(1,1-Difluoro-5-azaspiro[2.5]octan-5-yl)piperidin-1-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 4.50							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642987	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642987&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735073	490945405							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362584	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CCC2)c(F)c1	InChI=1S/C25H33F2N5O2S/c26-18-11-21(27)22(28-12-18)13-29-24(33)23-14-30-25(35-23)31-9-6-19(7-10-31)32-8-2-5-20(15-32)34-16-17-3-1-4-17/h11-12,14,17,19-20H,1-10,13,15-16H2,(H,29,33)	JLGCDTMMQVNEKF-UHFFFAOYSA-N	50574217	CHEMBL4866383::US20240000767, Example 126	Alpha-2C adrenergic receptor			 1.50							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574217&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735188	471064362							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362585	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CC2)c(F)c1	InChI=1S/C24H31F2N5O2S/c25-17-10-20(26)21(27-11-17)12-28-23(32)22-13-29-24(34-22)30-8-5-18(6-9-30)31-7-1-2-19(14-31)33-15-16-3-4-16/h10-11,13,16,18-19H,1-9,12,14-15H2,(H,28,32)	MUVLKMBCLRRGJM-UHFFFAOYSA-N	642989	US20240000767, Example 67::rac-2-[3-(Cyclopropylmethoxy)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 2.20							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642989	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642989&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735050	490945407							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362586	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COC3CCC3)C2)c(F)c1	InChI=1S/C25H33F2N5O2S/c26-18-11-21(27)22(28-12-18)13-29-24(33)23-14-30-25(35-23)31-9-6-19(7-10-31)32-8-2-3-17(15-32)16-34-20-4-1-5-20/h11-12,14,17,19-20H,1-10,13,15-16H2,(H,29,33)	KMNWWCLNNWZFIT-UHFFFAOYSA-N	50574215	CHEMBL4878875::US20240000767, Example 102	Alpha-2C adrenergic receptor			 4.30							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574215	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574215&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735109	471064360							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362587	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COCC3CC3)C2)c(F)c1	InChI=1S/C25H33F2N5O2S/c26-19-10-21(27)22(28-11-19)12-29-24(33)23-13-30-25(35-23)31-8-5-20(6-9-31)32-7-1-2-18(14-32)16-34-15-17-3-4-17/h10-11,13,17-18,20H,1-9,12,14-16H2,(H,29,33)	MBJKGPICTNTEBH-UHFFFAOYSA-N	642991	US20240000767, Example 115::US20240000767, Example 116::US20240000767, Example 69::rac-2-{3-[(Cyclopropylmethoxy)methyl][1,4&#8242;-bipiperidin]-1&#8242;-yl}-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 5.50							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642991&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735067	490945409							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362588	CCOC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5O2S/c1-2-31-17-4-3-7-29(14-17)16-5-8-28(9-6-16)22-27-13-20(32-22)21(30)26-12-19-18(24)10-15(23)11-25-19/h10-11,13,16-17H,2-9,12,14H2,1H3,(H,26,30)	OLYSADJEDIZFAA-UHFFFAOYSA-N	642992	US20240000767, Example 123::US20240000767, Example 124::US20240000767, Example 70::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-ethoxy[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 22.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642992	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642992&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735215	490945410							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362589	C[C@@H]1CCCN(C1)C1CCCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5OS/c1-15-4-2-8-29(14-15)17-5-3-7-28(9-6-17)22-27-13-20(31-22)21(30)26-12-19-18(24)10-16(23)11-25-19/h10-11,13,15,17H,2-9,12,14H2,1H3,(H,26,30)/t15-,17?/m1/s1	GTHWOCNZGDQEGI-LDCVWXEPSA-N	642993	N-[(3,5-Difluoropyridin-2-yl)methyl]-2-{4-[(3R)-3-methylpiperidin-1-yl]azepan-1-yl}-1,3-thiazole-5-carboxamide::US20240000767, Example 71	Alpha-2C adrenergic receptor			 100.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642993&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735029	490945411							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362590	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccc(C)nc1	InChI=1S/C22H31N5OS/c1-16-4-3-9-27(15-16)19-7-10-26(11-8-19)22-25-14-20(29-22)21(28)24-13-18-6-5-17(2)23-12-18/h5-6,12,14,16,19H,3-4,7-11,13,15H2,1-2H3,(H,24,28)/t16-/m1/s1	AJLKCJZUORVRKL-MRXNPFEDSA-N	642994	2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[(6-methylpyridin-3-yl)methyl]-1,3-thiazole-5-carboxamide::US20240000767, Example 72	Alpha-2C adrenergic receptor			 180							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642994&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735195	490945412							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362591	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccccc1	InChI=1S/C22H30N4OS/c1-17-6-5-11-26(16-17)19-9-12-25(13-10-19)22-24-15-20(28-22)21(27)23-14-18-7-3-2-4-8-18/h2-4,7-8,15,17,19H,5-6,9-14,16H2,1H3,(H,23,27)/t17-/m1/s1	DJHYQUQQPYFYIV-QGZVFWFLSA-N	642995	N-Benzyl-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 73	Alpha-2C adrenergic receptor			 219							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642995&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735128	490945413							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362592	CC(F)CCOCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C25H34F3N5O2S/c1-17(26)6-10-35-16-18-3-2-7-33(15-18)20-4-8-32(9-5-20)25-31-14-23(36-25)24(34)30-13-22-21(28)11-19(27)12-29-22/h11-12,14,17-18,20H,2-10,13,15-16H2,1H3,(H,30,34)	GCFWNWURVCANBF-UHFFFAOYSA-N	642996	US20240000767, Example 74::diamix-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-({[3-fluorobutyl]oxy}methyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 285							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642996&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735157	490945414							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362593	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COCC3CC(F)(F)C3)C2)c(F)c1	InChI=1S/C26H33F4N5O2S/c27-19-8-21(28)22(31-11-19)12-32-24(36)23-13-33-25(38-23)34-6-3-20(4-7-34)35-5-1-2-17(14-35)15-37-16-18-9-26(29,30)10-18/h8,11,13,17-18,20H,1-7,9-10,12,14-16H2,(H,32,36)	ZLUCGDNPVAGOFA-UHFFFAOYSA-N	642997	US20240000767, Example 75::rac-2-(3-{[(3,3-Difluorocyclobutyl)methoxy]methyl}[1,4&#8242;-bipiperidin]-1&#8242;-yl)-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 345							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642997	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642997&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735201	490945415							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362594	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccncc1F	InChI=1S/C21H28FN5OS/c1-15-3-2-8-27(14-15)17-5-9-26(10-6-17)21-25-13-19(29-21)20(28)24-11-16-4-7-23-12-18(16)22/h4,7,12-13,15,17H,2-3,5-6,8-11,14H2,1H3,(H,24,28)/t15-/m1/s1	SNHFCNFUGHCTCV-OAHLLOKOSA-N	642998	N-[(3-Fluoropyridin-4-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 76	Alpha-2C adrenergic receptor			 400							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642998	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642998&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735077	490945416							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362595	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC(F)(F)F)c(F)c1	InChI=1S/C22H26F5N5O2S/c23-14-8-17(24)18(28-9-14)10-29-20(33)19-11-30-21(35-19)31-6-3-15(4-7-31)32-5-1-2-16(12-32)34-13-22(25,26)27/h8-9,11,15-16H,1-7,10,12-13H2,(H,29,33)	OUQZWJCRNAPWAV-UHFFFAOYSA-N	642999	US20240000767, Example 77::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-(2,2,2-trifluoroethoxy)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 640							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642999	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642999&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735137	490945417							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362596	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cnc(C)cc1C	InChI=1S/C23H33N5OS/c1-16-5-4-8-28(15-16)20-6-9-27(10-7-20)23-26-14-21(30-23)22(29)25-13-19-12-24-18(3)11-17(19)2/h11-12,14,16,20H,4-10,13,15H2,1-3H3,(H,25,29)/t16-/m1/s1	MCQINDLAKRQFEZ-MRXNPFEDSA-N	643000	N-[(4,6-Dimethylpyridin-3-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 78	Alpha-2C adrenergic receptor			 755							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643000&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735145	490945418							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362597	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1c(Cl)cnn1C	InChI=1S/C20H29ClN6OS/c1-14-4-3-7-27(13-14)15-5-8-26(9-6-15)20-23-12-18(29-20)19(28)22-11-17-16(21)10-24-25(17)2/h10,12,14-15H,3-9,11,13H2,1-2H3,(H,22,28)/t14-/m1/s1	QYKPNLCXIDUXSW-CQSZACIVSA-N	643001	N-[(4-Chloro-1-methyl-1H-pyrazol-5-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 79	Alpha-2C adrenergic receptor			 50.3							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643001	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643001&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156734997	490945419							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362598	COc1cccc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCC[C@@H](C)C2)c1	InChI=1S/C23H32N4O2S/c1-17-5-4-10-27(16-17)19-8-11-26(12-9-19)23-25-15-21(30-23)22(28)24-14-18-6-3-7-20(13-18)29-2/h3,6-7,13,15,17,19H,4-5,8-12,14,16H2,1-2H3,(H,24,28)/t17-/m1/s1	FSNUCFVFZONFJE-QGZVFWFLSA-N	643002	US20240000767, Example 80	Alpha-2C adrenergic receptor			 90.5							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643002	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643002&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435050	490945420							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362599	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cc(F)ccc1F	InChI=1S/C22H28F2N4OS/c1-15-3-2-8-28(14-15)18-6-9-27(10-7-18)22-26-13-20(30-22)21(29)25-12-16-11-17(23)4-5-19(16)24/h4-5,11,13,15,18H,2-3,6-10,12,14H2,1H3,(H,25,29)/t15-/m1/s1	YBYQOZCFIZVCBY-OAHLLOKOSA-N	642969	US20240000767, Example 47::US20240000767, Example 81	Alpha-2C adrenergic receptor			 22.2							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642969	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642969&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735213	490945390							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362600	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cccc(O)c1	InChI=1S/C22H30N4O2S/c1-16-4-3-9-26(15-16)18-7-10-25(11-8-18)22-24-14-20(29-22)21(28)23-13-17-5-2-6-19(27)12-17/h2,5-6,12,14,16,18,27H,3-4,7-11,13,15H2,1H3,(H,23,28)/t16-/m1/s1	QILVETLUJQJGNV-MRXNPFEDSA-N	643004	US20240000767, Example 82	Alpha-2C adrenergic receptor			 102							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643004	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643004&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735005	490945421							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362601	CC(CNC(=O)c1cnc(s1)N1CCC(CC1)N1CCC[C@@H](C)C1)c1ccccc1	InChI=1S/C24H34N4OS/c1-18-7-6-12-28(17-18)21-10-13-27(14-11-21)24-26-16-22(30-24)23(29)25-15-19(2)20-8-4-3-5-9-20/h3-5,8-9,16,18-19,21H,6-7,10-15,17H2,1-2H3,(H,25,29)/t18-,19?/m1/s1	KRBKPHYWWYGGES-MRTLOADZSA-N	643005	US20240000767, Example 83	Alpha-2C adrenergic receptor			 98.1							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643005&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735154	490945422							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362602	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccc(F)cc1	InChI=1S/C22H29FN4OS/c1-16-3-2-10-27(15-16)19-8-11-26(12-9-19)22-25-14-20(29-22)21(28)24-13-17-4-6-18(23)7-5-17/h4-7,14,16,19H,2-3,8-13,15H2,1H3,(H,24,28)/t16-/m1/s1	YKTWDZYVZCZLJZ-MRXNPFEDSA-N	643006	US20240000767, Example 84	Alpha-2C adrenergic receptor			 65.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643006	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643006&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735209	490945423							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362603	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cccnc1	InChI=1S/C21H29N5OS/c1-16-4-3-9-26(15-16)18-6-10-25(11-7-18)21-24-14-19(28-21)20(27)23-13-17-5-2-8-22-12-17/h2,5,8,12,14,16,18H,3-4,6-7,9-11,13,15H2,1H3,(H,23,27)/t16-/m1/s1	FJRIFWQZIHYDMT-MRXNPFEDSA-N	643007	US20240000767, Example 85	Alpha-2C adrenergic receptor			 600							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643007&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735217	490945424							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362604	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cccc(F)c1	InChI=1S/C22H29FN4OS/c1-16-4-3-9-27(15-16)19-7-10-26(11-8-19)22-25-14-20(29-22)21(28)24-13-17-5-2-6-18(23)12-17/h2,5-6,12,14,16,19H,3-4,7-11,13,15H2,1H3,(H,24,28)/t16-/m1/s1	YOJNYVYHIYHFHP-MRXNPFEDSA-N	643008	US20240000767, Example 86	Alpha-2C adrenergic receptor			 28.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643008&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735047	490945425							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362605	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccccc1F	InChI=1S/C22H29FN4OS/c1-16-5-4-10-27(15-16)18-8-11-26(12-9-18)22-25-14-20(29-22)21(28)24-13-17-6-2-3-7-19(17)23/h2-3,6-7,14,16,18H,4-5,8-13,15H2,1H3,(H,24,28)/t16-/m1/s1	FKJPWJGWBOAONO-MRXNPFEDSA-N	643009	US20240000767, Example 87	Alpha-2C adrenergic receptor			 25.5							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643009	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643009&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435009	490945426							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362606	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cc(F)cc(Cl)c1	InChI=1S/C22H28ClFN4OS/c1-15-3-2-6-28(14-15)19-4-7-27(8-5-19)22-26-13-20(30-22)21(29)25-12-16-9-17(23)11-18(24)10-16/h9-11,13,15,19H,2-8,12,14H2,1H3,(H,25,29)/t15-/m1/s1	ADEDFZVLSPVHAM-OAHLLOKOSA-N	643010	US20240000767, Example 88	Alpha-2C adrenergic receptor			 489							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643010	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643010&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			170652329	490945427							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362607	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)Nc1ccc(F)c(c1)C#N	InChI=1S/C22H26FN5OS/c1-15-3-2-8-28(14-15)18-6-9-27(10-7-18)22-25-13-20(30-22)21(29)26-17-4-5-19(23)16(11-17)12-24/h4-5,11,13,15,18H,2-3,6-10,14H2,1H3,(H,26,29)/t15-/m1/s1	PLBKVYLOIRMHCK-OAHLLOKOSA-N	643011	US20240000767, Example 89	Alpha-2C adrenergic receptor			 230							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643011	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643011&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735165	490945428							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362608	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)N(C)Cc1cccnc1	InChI=1S/C22H31N5OS/c1-17-5-4-10-27(15-17)19-7-11-26(12-8-19)22-24-14-20(29-22)21(28)25(2)16-18-6-3-9-23-13-18/h3,6,9,13-14,17,19H,4-5,7-8,10-12,15-16H2,1-2H3/t17-/m1/s1	ORFZQIGUARGWRV-QGZVFWFLSA-N	643012	US20240000767, Example 90	Alpha-2C adrenergic receptor			 97.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643012	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643012&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162434983	490945429							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362609	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)N(C)Cc1ccncc1	InChI=1S/C22H31N5OS/c1-17-4-3-11-27(15-17)19-7-12-26(13-8-19)22-24-14-20(29-22)21(28)25(2)16-18-5-9-23-10-6-18/h5-6,9-10,14,17,19H,3-4,7-8,11-13,15-16H2,1-2H3/t17-/m1/s1	ITFQFYDPIGMOQJ-QGZVFWFLSA-N	643013	US20240000767, Example 91	Alpha-2C adrenergic receptor			 284							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643013	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643013&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735172	490945430							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362610	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)N(C)Cc1ccccc1	InChI=1S/C23H32N4OS/c1-18-7-6-12-27(16-18)20-10-13-26(14-11-20)23-24-15-21(29-23)22(28)25(2)17-19-8-4-3-5-9-19/h3-5,8-9,15,18,20H,6-7,10-14,16-17H2,1-2H3/t18-/m1/s1	BKCGWYZIBKIXIK-GOSISDBHSA-N	643014	US20240000767, Example 92	Alpha-2C adrenergic receptor			 85.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643014	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643014&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735004	490945431							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362611	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)Nc1ccccc1C1CC1	InChI=1S/C24H32N4OS/c1-17-5-4-12-28(16-17)19-10-13-27(14-11-19)24-25-15-22(30-24)23(29)26-21-7-3-2-6-20(21)18-8-9-18/h2-3,6-7,15,17-19H,4-5,8-14,16H2,1H3,(H,26,29)/t17-/m1/s1	NIYXOFSGXBPMRD-QGZVFWFLSA-N	643015	US20240000767, Example 93	Alpha-2C adrenergic receptor			 630							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643015	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643015&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735037	490945432							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362612	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1cccc(Cl)c1	InChI=1S/C22H29ClN4OS/c1-16-4-3-9-27(15-16)19-7-10-26(11-8-19)22-25-14-20(29-22)21(28)24-13-17-5-2-6-18(23)12-17/h2,5-6,12,14,16,19H,3-4,7-11,13,15H2,1H3,(H,24,28)/t16-/m1/s1	YEVQBXSCEUISLP-MRXNPFEDSA-N	643016	US20240000767, Example 94	Alpha-2C adrenergic receptor			 150							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643016	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643016&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435016	490945433							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362613	CC(NC(=O)c1cnc(s1)N1CCC(CC1)N1CCC[C@@H](C)C1)c1ccc(C)cc1	InChI=1S/C24H34N4OS/c1-17-6-8-20(9-7-17)19(3)26-23(29)22-15-25-24(30-22)27-13-10-21(11-14-27)28-12-4-5-18(2)16-28/h6-9,15,18-19,21H,4-5,10-14,16H2,1-3H3,(H,26,29)/t18-,19?/m1/s1	GNGRNDMCBCKQPA-MRTLOADZSA-N	643017	US20240000767, Example 95	Alpha-2C adrenergic receptor			 800							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643017&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166933435	490945434							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362614	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)Nc1cc(Cl)ccc1O	InChI=1S/C21H27ClN4O2S/c1-14-3-2-8-26(13-14)16-6-9-25(10-7-16)21-23-12-19(29-21)20(28)24-17-11-15(22)4-5-18(17)27/h4-5,11-12,14,16,27H,2-3,6-10,13H2,1H3,(H,24,28)/t14-/m1/s1	STTXTBWAQJHCME-CQSZACIVSA-N	643018	US20240000767, Example 96	Alpha-2C adrenergic receptor			 1000							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643018&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735216	490945435							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362615	COc1ccc(F)cc1NC(=O)c1cnc(s1)N1CCC(CC1)N1CCC[C@@H](C)C1	InChI=1S/C22H29FN4O2S/c1-15-4-3-9-27(14-15)17-7-10-26(11-8-17)22-24-13-20(30-22)21(28)25-18-12-16(23)5-6-19(18)29-2/h5-6,12-13,15,17H,3-4,7-11,14H2,1-2H3,(H,25,28)/t15-/m1/s1	QPMZNVADBWYUEK-OAHLLOKOSA-N	643019	US20240000767, Example 97	Alpha-2C adrenergic receptor			 1300							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643019&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735120	490945436							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362616	CCc1cc(NC(=O)c2cnc(s2)N2CCC(CC2)N2CCC[C@@H](C)C2)ccn1	InChI=1S/C22H31N5OS/c1-3-17-13-18(6-9-23-17)25-21(28)20-14-24-22(29-20)26-11-7-19(8-12-26)27-10-4-5-16(2)15-27/h6,9,13-14,16,19H,3-5,7-8,10-12,15H2,1-2H3,(H,23,25,28)/t16-/m1/s1	IFHHKKAHCKJOEC-MRXNPFEDSA-N	643020	US20240000767, Example 98	Alpha-2C adrenergic receptor			 1600							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643020	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643020&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735140	490945437							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362617	COCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5O2S/c1-31-14-15-3-2-6-29(13-15)17-4-7-28(8-5-17)22-27-12-20(32-22)21(30)26-11-19-18(24)9-16(23)10-25-19/h9-10,12,15,17H,2-8,11,13-14H2,1H3,(H,26,30)	ZGHRVPCMUPGYQM-UHFFFAOYSA-N	642921	US20240000767, Example 100::US20240000767, Example 48::US20240000767, Example 99::ent-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-(methoxymethyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide (enantiomer 2)	Alpha-2C adrenergic receptor			 590							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642921	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642921&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735052	490945349							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362618	COCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5O2S/c1-31-14-15-3-2-6-29(13-15)17-4-7-28(8-5-17)22-27-12-20(32-22)21(30)26-11-19-18(24)9-16(23)10-25-19/h9-10,12,15,17H,2-8,11,13-14H2,1H3,(H,26,30)	ZGHRVPCMUPGYQM-UHFFFAOYSA-N	642921	US20240000767, Example 100::US20240000767, Example 48::US20240000767, Example 99::ent-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-(methoxymethyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide (enantiomer 2)	Alpha-2C adrenergic receptor			 2.90							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642921	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642921&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735052	490945349							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362619	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COC3CCC3)C2)c(F)c1	InChI=1S/C25H33F2N5O2S/c26-18-11-21(27)22(28-12-18)13-29-24(33)23-14-30-25(35-23)31-9-6-19(7-10-31)32-8-2-3-17(15-32)16-34-20-4-1-5-20/h11-12,14,17,19-20H,1-10,13,15-16H2,(H,29,33)	KMNWWCLNNWZFIT-UHFFFAOYSA-N	50574215	CHEMBL4878875::US20240000767, Example 102	Alpha-2C adrenergic receptor			 2.30							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574215	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574215&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735109	471064360							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362620	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COC3CCC3)C2)c(F)c1	InChI=1S/C25H33F2N5O2S/c26-18-11-21(27)22(28-12-18)13-29-24(33)23-14-30-25(35-23)31-9-6-19(7-10-31)32-8-2-3-17(15-32)16-34-20-4-1-5-20/h11-12,14,17,19-20H,1-10,13,15-16H2,(H,29,33)	KMNWWCLNNWZFIT-UHFFFAOYSA-N	50574215	CHEMBL4878875::US20240000767, Example 102	Alpha-2C adrenergic receptor			 0.085							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574215	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574215&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735109	471064360							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362621	CC(C)C1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C23H31F2N5OS/c1-15(2)16-4-3-7-30(14-16)18-5-8-29(9-6-18)23-28-13-21(32-23)22(31)27-12-20-19(25)10-17(24)11-26-20/h10-11,13,15-16,18H,3-9,12,14H2,1-2H3,(H,27,31)	QRSWMDSTVFUENC-UHFFFAOYSA-N	643024	US20240000767, Example 103::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-(3-isopropyl[1,4&#8242;-bipiperidin]-1&#8242;-yl)-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 0.830							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643024	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643024&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735053	490945440							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362622	CC1CCCN(CC1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5OS/c1-15-3-2-7-28(8-4-15)17-5-9-29(10-6-17)22-27-14-20(31-22)21(30)26-13-19-18(24)11-16(23)12-25-19/h11-12,14-15,17H,2-10,13H2,1H3,(H,26,30)	WIZHCLUYDUKIJF-UHFFFAOYSA-N	642975	US20240000767, Example 104::US20240000767, Example 105::US20240000767, Example 53::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[4-(4-methylazepan-1-yl)piperidin-1-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 10.00							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642975&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735026	490945393							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362623	CC1CCCN(CC1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5OS/c1-15-3-2-7-28(8-4-15)17-5-9-29(10-6-17)22-27-14-20(31-22)21(30)26-13-19-18(24)11-16(23)12-25-19/h11-12,14-15,17H,2-10,13H2,1H3,(H,26,30)	WIZHCLUYDUKIJF-UHFFFAOYSA-N	642975	US20240000767, Example 104::US20240000767, Example 105::US20240000767, Example 53::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[4-(4-methylazepan-1-yl)piperidin-1-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 4.30							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642975&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735026	490945393							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362624	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COCC(F)(F)F)C2)c(F)c1	InChI=1S/C23H28F5N5O2S/c24-16-8-18(25)19(29-9-16)10-30-21(34)20-11-31-22(36-20)32-6-3-17(4-7-32)33-5-1-2-15(12-33)13-35-14-23(26,27)28/h8-9,11,15,17H,1-7,10,12-14H2,(H,30,34)	MGVMZZPBXYYHDX-UHFFFAOYSA-N	642981	US20240000767, Example 106::US20240000767, Example 107::US20240000767, Example 59::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-{3-[(2,2,2-trifluoroethoxy)methyl][1,4&#8242;-bipiperidin]-1&#8242;-yl}-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 0.500							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642981	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642981&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735224	490945399							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362625	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COCC(F)(F)F)C2)c(F)c1	InChI=1S/C23H28F5N5O2S/c24-16-8-18(25)19(29-9-16)10-30-21(34)20-11-31-22(36-20)32-6-3-17(4-7-32)33-5-1-2-15(12-33)13-35-14-23(26,27)28/h8-9,11,15,17H,1-7,10,12-14H2,(H,30,34)	MGVMZZPBXYYHDX-UHFFFAOYSA-N	642981	US20240000767, Example 106::US20240000767, Example 107::US20240000767, Example 59::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-{3-[(2,2,2-trifluoroethoxy)methyl][1,4&#8242;-bipiperidin]-1&#8242;-yl}-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 37.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642981	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642981&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735224	490945399							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362626	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CC2(F)F)c(F)c1	InChI=1S/C24H29F4N5O2S/c25-16-8-19(26)20(29-10-16)11-30-22(34)21-12-31-23(36-21)32-6-3-17(4-7-32)33-5-1-2-18(13-33)35-14-15-9-24(15,27)28/h8,10,12,15,17-18H,1-7,9,11,13-14H2,(H,30,34)	YAJMPZFDYPOFQB-UHFFFAOYSA-N	50574216	CHEMBL4876214::US20240000767, Example 108	Alpha-2C adrenergic receptor			 0.370							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574216&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735115	471064361							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362627	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OC2CCC2)c(F)c1	InChI=1S/C24H31F2N5O2S/c25-16-11-20(26)21(27-12-16)13-28-23(32)22-14-29-24(34-22)30-9-6-17(7-10-30)31-8-2-5-19(15-31)33-18-3-1-4-18/h11-12,14,17-19H,1-10,13,15H2,(H,28,32)	PQSFSDBBIGAKMY-UHFFFAOYSA-N	643030	US20240000767, Example 109::rac-2-[3-(Cyclobutyloxy)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 0.850							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643030	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643030&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735183	490945442							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362628	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OC2CC(F)(F)C2)c(F)c1	InChI=1S/C24H29F4N5O2S/c25-15-8-19(26)20(29-11-15)12-30-22(34)21-13-31-23(36-21)32-6-3-16(4-7-32)33-5-1-2-17(14-33)35-18-9-24(27,28)10-18/h8,11,13,16-18H,1-7,9-10,12,14H2,(H,30,34)	TXNAGJKGFLZIGC-UHFFFAOYSA-N	643031	US20240000767, Example 110::rac-2-{3-[(3,3-Difluorocyclobutyl)oxy][1,4&#8242;-bipiperidin]-1&#8242;-yl}-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 1.50							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643031&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735127	490945443							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362629	C[C@@H]1CCCN(C1)C1CCN(CC1F)c1nc(cs1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H26F3N5OS/c1-13-3-2-5-28(10-13)19-4-6-29(11-16(19)24)21-27-18(12-31-21)20(30)26-9-17-15(23)7-14(22)8-25-17/h7-8,12-13,16,19H,2-6,9-11H2,1H3,(H,26,30)/t13-,16?,19?/m1/s1	XAKCPRDPHQCQFB-DAIYRKSASA-N	643032	US20240000767, Example 111::diamix-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3&#8242;-fluoro-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-4-carboxamide	Alpha-2C adrenergic receptor			 0.490							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643032	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643032&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735155	490945444							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362630	C[C@@H]1CCCN(C1)C1CCN(CC1F)c1nc(co1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H26F3N5O2/c1-13-3-2-5-28(10-13)19-4-6-29(11-16(19)24)21-27-18(12-31-21)20(30)26-9-17-15(23)7-14(22)8-25-17/h7-8,12-13,16,19H,2-6,9-11H2,1H3,(H,26,30)/t13-,16?,19?/m1/s1	IOJRZQDGTDXSAE-DAIYRKSASA-N	643033	US20240000767, Example 112::diamix-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3&#8242;-fluoro-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-oxazole-4-carboxamide	Alpha-2C adrenergic receptor			 1.20							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643033	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643033&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735087	490945445							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362631	C[C@@H]1CCCN(C1)C1CCN(CC1F)c1ncc(s1)C(=O)NCc1cc(Cl)ccc1F	InChI=1S/C22H27ClF2N4OS/c1-14-3-2-7-28(12-14)19-6-8-29(13-18(19)25)22-27-11-20(31-22)21(30)26-10-15-9-16(23)4-5-17(15)24/h4-5,9,11,14,18-19H,2-3,6-8,10,12-13H2,1H3,(H,26,30)/t14-,18?,19?/m1/s1	XIZWKZVVTMJKFY-FTXHTYHOSA-N	643034	US20240000767, Example 113::diamix-N-(5-Chloro-2-fluorobenzyl)-2-[(3R)-3&#8242;-fluoro-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 0.610							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643034	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643034&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735009	490945446							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362632	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCC[C@H](C2)OCC2CC2)c(F)c1	InChI=1S/C24H31F2N5O2S/c25-17-10-20(26)21(27-11-17)12-28-23(32)22-13-29-24(34-22)30-8-5-18(6-9-30)31-7-1-2-19(14-31)33-15-16-3-4-16/h10-11,13,16,18-19H,1-9,12,14-15H2,(H,28,32)/t19-/m1/s1	MUVLKMBCLRRGJM-LJQANCHMSA-N	643035	2-[(3R)-3-(Cyclopropylmethoxy)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide::US20240000767, Example 114	Alpha-2C adrenergic receptor			 1.30							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643035	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643035&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735107	490945447							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362633	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COCC3CC3)C2)c(F)c1	InChI=1S/C25H33F2N5O2S/c26-19-10-21(27)22(28-11-19)12-29-24(33)23-13-30-25(35-23)31-8-5-20(6-9-31)32-7-1-2-18(14-32)16-34-15-17-3-4-17/h10-11,13,17-18,20H,1-9,12,14-16H2,(H,29,33)	MBJKGPICTNTEBH-UHFFFAOYSA-N	642991	US20240000767, Example 115::US20240000767, Example 116::US20240000767, Example 69::rac-2-{3-[(Cyclopropylmethoxy)methyl][1,4&#8242;-bipiperidin]-1&#8242;-yl}-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 0.610							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642991&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735067	490945409							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362634	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COCC3CC3)C2)c(F)c1	InChI=1S/C25H33F2N5O2S/c26-19-10-21(27)22(28-11-19)12-29-24(33)23-13-30-25(35-23)31-8-5-20(6-9-31)32-7-1-2-18(14-32)16-34-15-17-3-4-17/h10-11,13,17-18,20H,1-9,12,14-16H2,(H,29,33)	MBJKGPICTNTEBH-UHFFFAOYSA-N	642991	US20240000767, Example 115::US20240000767, Example 116::US20240000767, Example 69::rac-2-{3-[(Cyclopropylmethoxy)methyl][1,4&#8242;-bipiperidin]-1&#8242;-yl}-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 11.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642991&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735067	490945409							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362635	CC(NC(=O)c1cnc(s1)N1CCC(C(F)C1)N1CCC[C@@H](C)C1)c1cc(F)ccc1F	InChI=1S/C23H29F3N4OS/c1-14-4-3-8-29(12-14)20-7-9-30(13-19(20)26)23-27-11-21(32-23)22(31)28-15(2)17-10-16(24)5-6-18(17)25/h5-6,10-11,14-15,19-20H,3-4,7-9,12-13H2,1-2H3,(H,28,31)/t14-,15?,19?,20?/m1/s1	PTRXQRSHVTXSJT-FGBLYHGVSA-N	643038	US20240000767, Example 117::diamix-N-[1-(2,5-Difluorophenyl)ethyl]-2-[(3R)-3&#8242;-fluoro-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 0.650							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643038	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643038&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162434999	490945448							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362636	C[C@@H]1CCCN(C1)C1CCN(CC1)c1nc(c(s1)C(=O)NCc1ncc(F)cc1F)-c1ccccc1Cl	InChI=1S/C27H30ClF2N5OS/c1-17-5-4-10-35(16-17)19-8-11-34(12-9-19)27-33-24(20-6-2-3-7-21(20)28)25(37-27)26(36)32-15-23-22(30)13-18(29)14-31-23/h2-3,6-7,13-14,17,19H,4-5,8-12,15-16H2,1H3,(H,32,36)/t17-/m1/s1	BPBMGUATNUDFQS-QGZVFWFLSA-N	643039	4-(2-Chlorophenyl)-N-[(3,5-difluoropyridin-2-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 118	Alpha-2C adrenergic receptor			 7.70							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643039	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643039&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735198	490945449							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362637	C[C@@H]1CCCN(C1)C1CCN(CC1)c1nc(Br)c(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H26BrF2N5OS/c1-13-3-2-6-29(12-13)15-4-7-28(8-5-15)21-27-19(22)18(31-21)20(30)26-11-17-16(24)9-14(23)10-25-17/h9-10,13,15H,2-8,11-12H2,1H3,(H,26,30)/t13-/m1/s1	XYQVSBLNBAVPHL-CYBMUJFWSA-N	643040	4-Bromo-N-[(3,5-difluoropyridin-2-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 119	Alpha-2C adrenergic receptor			 30.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643040	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643040&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735132	490945450							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362638	C[C@@H]1CCCN(C1)C1CCN(CC1)c1nc(Cl)c(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H26ClF2N5OS/c1-13-3-2-6-29(12-13)15-4-7-28(8-5-15)21-27-19(22)18(31-21)20(30)26-11-17-16(24)9-14(23)10-25-17/h9-10,13,15H,2-8,11-12H2,1H3,(H,26,30)/t13-/m1/s1	IOMRPTUJPIQXAG-CYBMUJFWSA-N	643041	4-Chloro-N-[(3,5-difluoropyridin-2-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 120	Alpha-2C adrenergic receptor			 41.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643041	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643041&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156734998	490945451							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362639	CCCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C23H31F2N5OS/c1-2-4-16-5-3-8-30(15-16)18-6-9-29(10-7-18)23-28-14-21(32-23)22(31)27-13-20-19(25)11-17(24)12-26-20/h11-12,14,16,18H,2-10,13,15H2,1H3,(H,27,31)	GAAAAVSJTFUHMO-UHFFFAOYSA-N	643042	US20240000767, Example 121::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-(3-propyl[1,4&#8242;-bipiperidin]-1&#8242;-yl)-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 0.650							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643042&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735214	490945452							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362640	C[C@@H]1CCCN(C1)C1CCN(CC1)c1nc(C2CC2)c(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C24H31F2N5OS/c1-15-3-2-8-31(14-15)18-6-9-30(10-7-18)24-29-21(16-4-5-16)22(33-24)23(32)28-13-20-19(26)11-17(25)12-27-20/h11-12,15-16,18H,2-10,13-14H2,1H3,(H,28,32)/t15-/m1/s1	ZBXMQCZZIAFPAW-OAHLLOKOSA-N	643043	4-Cyclopropyl-N-[(3,5-difluoropyridin-2-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 122	Alpha-2C adrenergic receptor			 13.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643043&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735000	490945453							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362641	CCOC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5O2S/c1-2-31-17-4-3-7-29(14-17)16-5-8-28(9-6-16)22-27-13-20(32-22)21(30)26-12-19-18(24)10-15(23)11-25-19/h10-11,13,16-17H,2-9,12,14H2,1H3,(H,26,30)	OLYSADJEDIZFAA-UHFFFAOYSA-N	642992	US20240000767, Example 123::US20240000767, Example 124::US20240000767, Example 70::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-ethoxy[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 260							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642992	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642992&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735215	490945410							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362642	CCOC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H29F2N5O2S/c1-2-31-17-4-3-7-29(14-17)16-5-8-28(9-6-16)22-27-13-20(32-22)21(30)26-12-19-18(24)10-15(23)11-25-19/h10-11,13,16-17H,2-9,12,14H2,1H3,(H,26,30)	OLYSADJEDIZFAA-UHFFFAOYSA-N	642992	US20240000767, Example 123::US20240000767, Example 124::US20240000767, Example 70::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[3-ethoxy[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 2.90							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642992	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642992&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735215	490945410							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362643	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CCC2)c(F)c1	InChI=1S/C25H33F2N5O2S/c26-18-11-21(27)22(28-12-18)13-29-24(33)23-14-30-25(35-23)31-9-6-19(7-10-31)32-8-2-5-20(15-32)34-16-17-3-1-4-17/h11-12,14,17,19-20H,1-10,13,15-16H2,(H,29,33)	JLGCDTMMQVNEKF-UHFFFAOYSA-N	50574217	CHEMBL4866383::US20240000767, Example 126	Alpha-2C adrenergic receptor			 0.490							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574217&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735188	471064362							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362644	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CCC2)c(F)c1	InChI=1S/C25H33F2N5O2S/c26-18-11-21(27)22(28-12-18)13-29-24(33)23-14-30-25(35-23)31-9-6-19(7-10-31)32-8-2-5-20(15-32)34-16-17-3-1-4-17/h11-12,14,17,19-20H,1-10,13,15-16H2,(H,29,33)	JLGCDTMMQVNEKF-UHFFFAOYSA-N	50574217	CHEMBL4866383::US20240000767, Example 126	Alpha-2C adrenergic receptor			 2.30							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574217&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735188	471064362							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362645	FCCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H28F3N5OS/c23-6-3-15-2-1-7-30(14-15)17-4-8-29(9-5-17)22-28-13-20(32-22)21(31)27-12-19-18(25)10-16(24)11-26-19/h10-11,13,15,17H,1-9,12,14H2,(H,27,31)	BOUCTEFFKNSSDL-UHFFFAOYSA-N	643048	US20240000767, Example 127::rac-Formic acid N-[(3,5-difluoropyridin-2-yl)methyl]-2-[3-(2-fluoroethyl)[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 8.40							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643048	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643048&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735106	490945456							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362646	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCCC2)c(F)c1	InChI=1S/C20H25F2N5OS/c21-14-10-16(22)17(23-11-14)12-24-19(28)18-13-25-20(29-18)27-8-4-15(5-9-27)26-6-2-1-3-7-26/h10-11,13,15H,1-9,12H2,(H,24,28)	JZNDZDOVIMYXED-UHFFFAOYSA-N	643049	2-([1,4&#8242;-Bipiperidin]-1&#8242;-yl)-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide::US20240000767, Example 128	Alpha-2C adrenergic receptor			 550							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643049	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643049&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735189	490945457							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362647	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NC1(CC1)c1ncc(F)cc1F	InChI=1S/C23H29F2N5OS/c1-15-3-2-8-30(14-15)17-4-9-29(10-5-17)22-27-13-19(32-22)21(31)28-23(6-7-23)20-18(25)11-16(24)12-26-20/h11-13,15,17H,2-10,14H2,1H3,(H,28,31)/t15-/m1/s1	RPWCRNRZERJCAD-OAHLLOKOSA-N	643050	N-[1-(3,5-Difluoropyridin-2-yl)cyclopropyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 129	Alpha-2C adrenergic receptor			 10.00							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643050&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735220	490945458							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362648	CCc1nc(sc1C(=O)NCc1ncc(F)cc1F)N1CCC(CC1)N1CCC[C@@H](C)C1	InChI=1S/C23H31F2N5OS/c1-3-19-21(22(31)27-13-20-18(25)11-16(24)12-26-20)32-23(28-19)29-9-6-17(7-10-29)30-8-4-5-15(2)14-30/h11-12,15,17H,3-10,13-14H2,1-2H3,(H,27,31)/t15-/m1/s1	QONUDKILKDMADU-OAHLLOKOSA-N	643051	N-[(3,5-Difluoropyridin-2-yl)methyl]-4-ethyl-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 130	Alpha-2C adrenergic receptor			 0.540							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643051&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735061	490945459							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362649	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC3(CC3(F)F)C2)c(F)c1	InChI=1S/C22H25F4N5OS/c23-14-8-16(24)17(27-9-14)10-28-19(32)18-11-29-20(33-18)30-6-2-15(3-7-30)31-5-1-4-21(13-31)12-22(21,25)26/h8-9,11,15H,1-7,10,12-13H2,(H,28,32)	GEIIJNRSUPZTGW-UHFFFAOYSA-N	642987	US20240000767, Example 131::US20240000767, Example 132::US20240000767, Example 65::rac-2-[4-(1,1-Difluoro-5-azaspiro[2.5]octan-5-yl)piperidin-1-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 1.90							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642987	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642987&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735073	490945405							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362650	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC3(CC3(F)F)C2)c(F)c1	InChI=1S/C22H25F4N5OS/c23-14-8-16(24)17(27-9-14)10-28-19(32)18-11-29-20(33-18)30-6-2-15(3-7-30)31-5-1-4-21(13-31)12-22(21,25)26/h8-9,11,15H,1-7,10,12-13H2,(H,28,32)	GEIIJNRSUPZTGW-UHFFFAOYSA-N	642987	US20240000767, Example 131::US20240000767, Example 132::US20240000767, Example 65::rac-2-[4-(1,1-Difluoro-5-azaspiro[2.5]octan-5-yl)piperidin-1-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 0.710							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642987	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642987&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735073	490945405							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362651	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)c2ccccc2)c(F)c1	InChI=1S/C26H29F2N5OS/c27-20-13-22(28)23(29-14-20)15-30-25(34)24-16-31-26(35-24)32-11-8-21(9-12-32)33-10-4-7-19(17-33)18-5-2-1-3-6-18/h1-3,5-6,13-14,16,19,21H,4,7-12,15,17H2,(H,30,34)	VJPHJUDXYLAVDA-UHFFFAOYSA-N	643054	US20240000767, Example 133::rac-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-(3-phenyl[1,4&#8242;-bipiperidin]-1&#8242;-yl)-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 0.950							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643054&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735066	490945460							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362652	FC1CN(CCC1N1CCCC2(CC2(F)F)C1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H24F5N5OS/c23-13-6-14(24)16(28-7-13)8-29-19(33)18-9-30-20(34-18)31-5-2-17(15(25)10-31)32-4-1-3-21(12-32)11-22(21,26)27/h6-7,9,15,17H,1-5,8,10-12H2,(H,29,33)	WJPCAIFTUMAFAE-UHFFFAOYSA-N	643055	US20240000767, Example 134::diamix-2-[4-(1,1-Difluoro-5-azaspiro[2.5]octan-5-yl)-3-fluoropiperidin-1-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide	Alpha-2C adrenergic receptor			 0.740							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643055&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735003	490945461							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362653	FC1CN(CCC1N1CCCC2(CC2)C1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C22H26F3N5OS/c23-14-8-15(24)17(26-9-14)10-27-20(31)19-11-28-21(32-19)29-7-2-18(16(25)12-29)30-6-1-3-22(13-30)4-5-22/h8-9,11,16,18H,1-7,10,12-13H2,(H,27,31)	LKPAKMYDZQMMOO-UHFFFAOYSA-N	50574218	CHEMBL4875484::US20240000767, Example 135	Alpha-2C adrenergic receptor			 0.260							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574218&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735161	471064363							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362654	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC3(COC3)C2)c(F)c1	InChI=1S/C22H27F2N5O2S/c23-15-8-17(24)18(25-9-15)10-26-20(30)19-11-27-21(32-19)28-6-2-16(3-7-28)29-5-1-4-22(12-29)13-31-14-22/h8-9,11,16H,1-7,10,12-14H2,(H,26,30)	IFTYOSKCKPNDFA-UHFFFAOYSA-N	643057	US20240000767, Example 136	Alpha-2C adrenergic receptor			 320							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643057	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643057&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166933442	490945463							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362655	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)C2CC2)c(F)c1	InChI=1S/C23H29F2N5OS/c24-17-10-19(25)20(26-11-17)12-27-22(31)21-13-28-23(32-21)29-8-5-18(6-9-29)30-7-1-2-16(14-30)15-3-4-15/h10-11,13,15-16,18H,1-9,12,14H2,(H,27,31)	GBJCFYGBBFYMFQ-UHFFFAOYSA-N	643058	US20240000767, Example 137	Alpha-2C adrenergic receptor			 19.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643058&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735075	490945464							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362656	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)C2CCC2)c(F)c1	InChI=1S/C24H31F2N5OS/c25-18-11-20(26)21(27-12-18)13-28-23(32)22-14-29-24(33-22)30-9-6-19(7-10-30)31-8-2-5-17(15-31)16-3-1-4-16/h11-12,14,16-17,19H,1-10,13,15H2,(H,28,32)	AUYDTGXOFMOOEG-UHFFFAOYSA-N	643059	US20240000767, Example 138	Alpha-2C adrenergic receptor			 6.50							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643059	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643059&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735190	490945465							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362657	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCc3ccc(Cl)cc3C2)c(F)c1	InChI=1S/C24H24ClF2N5OS/c25-17-2-1-15-3-6-32(14-16(15)9-17)19-4-7-31(8-5-19)24-30-13-22(34-24)23(33)29-12-21-20(27)10-18(26)11-28-21/h1-2,9-11,13,19H,3-8,12,14H2,(H,29,33)	ZNYMEQBOVDIGIZ-UHFFFAOYSA-N	643060	US20240000767, Example 139	Alpha-2C adrenergic receptor			 0.650							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643060&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166933409	490945466							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362658	COc1cccc2CCN(Cc12)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C25H27F2N5O2S/c1-34-22-4-2-3-16-5-8-32(15-19(16)22)18-6-9-31(10-7-18)25-30-14-23(35-25)24(33)29-13-21-20(27)11-17(26)12-28-21/h2-4,11-12,14,18H,5-10,13,15H2,1H3,(H,29,33)	YBUVVPDQNUYGOE-UHFFFAOYSA-N	50574219	CHEMBL4852159::US20240000767, Example 140	Alpha-2C adrenergic receptor			 0.320							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574219	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574219&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			164617361	471064364							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362659	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCc3cccc(Cl)c3C2)c(F)c1	InChI=1S/C24H24ClF2N5OS/c25-19-3-1-2-15-4-7-32(14-18(15)19)17-5-8-31(9-6-17)24-30-13-22(34-24)23(33)29-12-21-20(27)10-16(26)11-28-21/h1-3,10-11,13,17H,4-9,12,14H2,(H,29,33)	YSVFEYPKWRELJY-UHFFFAOYSA-N	643062	US20240000767, Example 141	Alpha-2C adrenergic receptor			 8.70							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643062	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643062&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			168099545	490945468							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362660	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCc3c(Cl)cccc3C2)c(F)c1	InChI=1S/C24H24ClF2N5OS/c25-19-3-1-2-15-14-32(9-6-18(15)19)17-4-7-31(8-5-17)24-30-13-22(34-24)23(33)29-12-21-20(27)10-16(26)11-28-21/h1-3,10-11,13,17H,4-9,12,14H2,(H,29,33)	KTNFMERRLPTIGH-UHFFFAOYSA-N	643063	US20240000767, Example 142	Alpha-2C adrenergic receptor			 6.70							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643063	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643063&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			168099567	490945469							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362661	Cc1ccc2CCN(Cc2c1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C25H27F2N5OS/c1-16-2-3-17-4-7-32(15-18(17)10-16)20-5-8-31(9-6-20)25-30-14-23(34-25)24(33)29-13-22-21(27)11-19(26)12-28-22/h2-3,10-12,14,20H,4-9,13,15H2,1H3,(H,29,33)	KYGWRYJIKUTQPQ-UHFFFAOYSA-N	50574220	CHEMBL4868807::US20240000767, Example 143	Alpha-2C adrenergic receptor			 0.420							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50574220	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50574220&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735204	471064365							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362662	Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCc3cccc(F)c3C2)c(F)c1	InChI=1S/C24H24F3N5OS/c25-16-10-20(27)21(28-11-16)12-29-23(33)22-13-30-24(34-22)31-8-5-17(6-9-31)32-7-4-15-2-1-3-19(26)18(15)14-32/h1-3,10-11,13,17H,4-9,12,14H2,(H,29,33)	HJGRRONNDXXLSC-UHFFFAOYSA-N	643065	US20240000767, Example 144	Alpha-2C adrenergic receptor			 1.80							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643065	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643065&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735018	490945471							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362663	COc1ccc2CN(CCc2c1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C25H27F2N5O2S/c1-34-20-3-2-17-15-32(7-4-16(17)10-20)19-5-8-31(9-6-19)25-30-14-23(35-25)24(33)29-13-22-21(27)11-18(26)12-28-22/h2-3,10-12,14,19H,4-9,13,15H2,1H3,(H,29,33)	UFKZQBUPZWTVBU-UHFFFAOYSA-N	643066	US20240000767, Example 145	Alpha-2C adrenergic receptor			 1.000							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643066	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643066&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735090	490945472							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362664	Cc1ccc2CN(CCc2c1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C25H27F2N5OS/c1-16-2-3-18-15-32(7-4-17(18)10-16)20-5-8-31(9-6-20)25-30-14-23(34-25)24(33)29-13-22-21(27)11-19(26)12-28-22/h2-3,10-12,14,20H,4-9,13,15H2,1H3,(H,29,33)	BMVVPAUGLUJCHV-UHFFFAOYSA-N	643067	US20240000767, Example 146	Alpha-2C adrenergic receptor			 1.72							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643067	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643067&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735046	490945473							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362665	COCCC1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C23H31F2N5O2S/c1-32-10-6-16-3-2-7-30(15-16)18-4-8-29(9-5-18)23-28-14-21(33-23)22(31)27-13-20-19(25)11-17(24)12-26-20/h11-12,14,16,18H,2-10,13,15H2,1H3,(H,27,31)	QFBGZWGHWSKYJM-UHFFFAOYSA-N	643068	US20240000767, Example 148	Alpha-2C adrenergic receptor			 1.30							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643068	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643068&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735223	490945474							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362666	CC(C)(C)C1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C24H33F2N5OS/c1-24(2,3)16-5-4-8-31(15-16)18-6-9-30(10-7-18)23-29-14-21(33-23)22(32)28-13-20-19(26)11-17(25)12-27-20/h11-12,14,16,18H,4-10,13,15H2,1-3H3,(H,28,32)	ZDMBUJWEAQBQGH-UHFFFAOYSA-N	643069	US20240000767, Example 149	Alpha-2C adrenergic receptor			 35.0							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643069	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643069&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			162435019	490945475							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362667	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)N(C)Cc1ncc(F)cc1F	InChI=1S/C22H29F2N5OS/c1-15-4-3-7-29(13-15)17-5-8-28(9-6-17)22-26-12-20(31-22)21(30)27(2)14-19-18(24)10-16(23)11-25-19/h10-12,15,17H,3-9,13-14H2,1-2H3/t15-/m1/s1	CHCLXTQAVVIKQC-OAHLLOKOSA-N	643070	US20240000767, Example 150	Alpha-2C adrenergic receptor			 200							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643070	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643070&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166933432	490945476							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362668	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ccccc1Cl	InChI=1S/C22H29ClN4OS/c1-16-5-4-10-27(15-16)18-8-11-26(12-9-18)22-25-14-20(29-22)21(28)24-13-17-6-2-3-7-19(17)23/h2-3,6-7,14,16,18H,4-5,8-13,15H2,1H3,(H,24,28)/t16-/m1/s1	IGVWDVMNZZPWQZ-MRXNPFEDSA-N	643071	US20240000767, Example 151	Alpha-2C adrenergic receptor			 170							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=643071	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=643071&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			166933433	490945477							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
1362669	C[C@@H]1CCCN(C1)C1CCN(CC1)c1ncc(s1)C(=O)NCc1ncc(F)cc1F	InChI=1S/C21H27F2N5OS/c1-14-3-2-6-28(13-14)16-4-7-27(8-5-16)21-26-12-19(30-21)20(29)25-11-18-17(23)9-15(22)10-24-18/h9-10,12,14,16H,2-8,11,13H2,1H3,(H,25,29)/t14-/m1/s1	MUEUIRFXUWDRNF-CQSZACIVSA-N	642917	N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3-methyl[1,4&#8242;-bipiperidin]-1&#8242;-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 1::US20240000767, Example 152	Alpha-2C adrenergic receptor			 660							US Patent		10.7270/Q23B649Z			US20240000767	DELBECK, M; HAHN, M	Bayer Aktiengesellschaft	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=642917	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=642917&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			156735054	490945348							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51522484	OC(=O)c1ccccc1Nc1cc(cc(c1)C(F)(F)F)C#C	InChI=1S/C16H10F3NO2/c1-2-10-7-11(16(17,18)19)9-12(8-10)20-14-6-4-3-5-13(14)15(21)22/h1,3-9,20H,(H,21,22)	ADYZEYUMYXAEPW-UHFFFAOYSA-N	50613023	CHEMBL5273955	Alpha-2C adrenergic receptor		 17000								ChEMBL		10.7270/Q25Q519R	36847646			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50613023	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50613023&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			171352812	494502771							1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
50986080	COc1ccc(CCNCC(O)COc2ccc(cc2)-c2ncc(Cl)[nH]2)cc1OC	InChI=1S/C22H26ClN3O4/c1-28-19-8-3-15(11-20(19)29-2)9-10-24-12-17(27)14-30-18-6-4-16(5-7-18)22-25-13-21(23)26-22/h3-8,11,13,17,24,27H,9-10,12,14H2,1-2H3,(H,25,26)	XEXJIIOIDAVATL-UHFFFAOYSA-N	50405434	CHEMBL5274312	Alpha-2C adrenergic receptor		 1100								ChEMBL		10.7270/Q29Z9923	36089113			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405434&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			13621680	163354458		CHEMBL416150				ZINC26018049	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51545176	CCCN1CCN(CC1)c1ccc2CCCC(N(C)C(=O)OCc3ccccc3)c2c1	InChI=1S/C26H35N3O2/c1-3-14-28-15-17-29(18-16-28)23-13-12-22-10-7-11-25(24(22)19-23)27(2)26(30)31-20-21-8-5-4-6-9-21/h4-6,8-9,12-13,19,25H,3,7,10-11,14-18,20H2,1-2H3	PBFDUYRSNDQIDN-UHFFFAOYSA-N	50621475	CHEMBL5403404	Alpha-2C adrenergic receptor	Homo sapiens	>10000								ChEMBL	10.1016/j.ejmech.2022.114696	10.7270/Q2F76HXN	36088757			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50621475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50621475&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51546456	[11CH3]OCc1cccnc1N1CCN(C[C@H]2COc3ccccc3O2)CC1	InChI=1S/C20H25N3O3/c1-24-14-16-5-4-8-21-20(16)23-11-9-22(10-12-23)13-17-15-25-18-6-2-3-7-19(18)26-17/h2-8,17H,9-15H2,1H3/t17-/m0/s1/i1-1	VGIYMYGMVXPMKV-GWDMYEQXSA-N	50621980	(11C)ORM-13070::11C-ORM-13070::11c-orm-13070::ORM-13070 C-11::Orm-13070 c-11	Alpha-2C adrenergic receptor	Homo sapiens			 3.8						ChEMBL	10.1021/acs.jmedchem.2c01965	10.7270/Q29C72TF	37145921			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50621980	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50621980&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51566590	CN(C)CCc1c[nH]c2ccccc12	InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3	DMULVCHRPCFFGV-UHFFFAOYSA-N	50026868	2-(1H-indol-3-yl)-N,N-dimethylethanamine::2-(3-indolyl)ethyldimethylamine::3-(2-dimethylaminoethyl)indole::3-[2-(dimethylamino)ethyl]indole::CHEMBL12420::DMT::N,N-dimethyl-1H-indole-3-ethylamine::N,N-dimethyltryptamine::US20240166618, Compound DMT::US20240246911, Compound DMT::WO2023019367, Compound DMT	Alpha-2C adrenergic receptor	Homo sapiens		 6100							ChEMBL	10.1021/acsmedchemlett.3c00143	10.7270/Q26Q22P8	37736183			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026868&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6089	103936452	28969	CHEMBL12420	DB01488	141	C08302	ZINC00897457	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51566591	CN(C)CCc1c[nH]c2ccccc12	InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3	DMULVCHRPCFFGV-UHFFFAOYSA-N	50026868	2-(1H-indol-3-yl)-N,N-dimethylethanamine::2-(3-indolyl)ethyldimethylamine::3-(2-dimethylaminoethyl)indole::3-[2-(dimethylamino)ethyl]indole::CHEMBL12420::DMT::N,N-dimethyl-1H-indole-3-ethylamine::N,N-dimethyltryptamine::US20240166618, Compound DMT::US20240246911, Compound DMT::WO2023019367, Compound DMT	Alpha-2C adrenergic receptor	Homo sapiens		 9470							ChEMBL	10.1021/acsmedchemlett.3c00143	10.7270/Q26Q22P8	37736183			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026868&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6089	103936452	28969	CHEMBL12420	DB01488	141	C08302	ZINC00897457	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51566624	CN(C)CCc1c[nH]c2ccccc12	InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3	DMULVCHRPCFFGV-UHFFFAOYSA-N	50026868	2-(1H-indol-3-yl)-N,N-dimethylethanamine::2-(3-indolyl)ethyldimethylamine::3-(2-dimethylaminoethyl)indole::3-[2-(dimethylamino)ethyl]indole::CHEMBL12420::DMT::N,N-dimethyl-1H-indole-3-ethylamine::N,N-dimethyltryptamine::US20240166618, Compound DMT::US20240246911, Compound DMT::WO2023019367, Compound DMT	Alpha-2C adrenergic receptor	Homo sapiens	 2710								ChEMBL	10.1021/acsmedchemlett.3c00143	10.7270/Q26Q22P8	37736183			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026868&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6089	103936452	28969	CHEMBL12420	DB01488	141	C08302	ZINC00897457	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51566625	CN(C)CCc1c[nH]c2ccccc12	InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3	DMULVCHRPCFFGV-UHFFFAOYSA-N	50026868	2-(1H-indol-3-yl)-N,N-dimethylethanamine::2-(3-indolyl)ethyldimethylamine::3-(2-dimethylaminoethyl)indole::3-[2-(dimethylamino)ethyl]indole::CHEMBL12420::DMT::N,N-dimethyl-1H-indole-3-ethylamine::N,N-dimethyltryptamine::US20240166618, Compound DMT::US20240246911, Compound DMT::WO2023019367, Compound DMT	Alpha-2C adrenergic receptor	Homo sapiens	 4210								ChEMBL	10.1021/acsmedchemlett.3c00143	10.7270/Q26Q22P8	37736183			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026868&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search			6089	103936452	28969	CHEMBL12420	DB01488	141	C08302	ZINC00897457	1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51555622	OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(c2c(NCc3ccccc3)ncnc12)C(F)(F)F	InChI=1S/C19H19F3N4O4/c20-19(21,22)11-7-26(18-15(29)14(28)12(8-27)30-18)17-13(11)16(24-9-25-17)23-6-10-4-2-1-3-5-10/h1-5,7,9,12,14-15,18,27-29H,6,8H2,(H,23,24,25)/t12-,14-,15-,18-/m1/s1	HKPIERLZGGUUMI-SCFUHWHPSA-N	50625921	CHEMBL5409958	Alpha-2C adrenergic receptor	Homo sapiens	 2500								ChEMBL	10.1021/acsmedchemlett.3c00427	10.7270/Q2M90F2K	38229744			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50625921	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50625921&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51533618	CCN(CC)CCCC(C)Nc1cnc(cn1)C(=O)Nc1cc(F)cc2cccnc12	InChI=1S/C23H29FN6O/c1-4-30(5-2)11-7-8-16(3)28-21-15-26-20(14-27-21)23(31)29-19-13-18(24)12-17-9-6-10-25-22(17)19/h6,9-10,12-16H,4-5,7-8,11H2,1-3H3,(H,27,28)(H,29,31)	DATRLTNBZWRBPI-UHFFFAOYSA-N	50616870	CHEMBL5431371	Alpha-2C adrenergic receptor	Homo sapiens	>10000								ChEMBL	10.1021/acs.jmedchem.2c01769	10.7270/Q28D01MQ	36692906			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50616870	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50616870&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49						
51536494	C(CN1CCN(CC1)c1ccccn1)Cc1nc2ccccc2s1	InChI=1S/C19H22N4S/c1-2-7-17-16(6-1)21-19(24-17)9-5-11-22-12-14-23(15-13-22)18-8-3-4-10-20-18/h1-4,6-8,10H,5,9,11-15H2	KZVXSSLUUGFVFR-UHFFFAOYSA-N	50618106	CHEMBL5400876	Alpha-2C adrenergic receptor	Homo sapiens	 72								ChEMBL	10.1021/acs.jmedchem.3c00734	10.7270/Q2XP7999	37646374			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50618106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9126&target=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50618106&enzyme=Alpha-2C+adrenergic+receptor&column=ki&startPg=0&Increment=50&submit=Search											1	MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ		Alpha-2C adrenergic receptor	ADA2C_HUMAN	P18825	P35369 Q9HB49