BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50447732 FC(F)(F)c1ccc(cc1)C(=O)n1ccc2ccccc12 InChI=1S/C16H10F3NO/c17-16(18,19)13-7-5-12(6-8-13)15(21)20-10-9-11-3-1-2-4-14(11)20/h1-10H NLBWJIRVAGJMJY-UHFFFAOYSA-N 50266599 (1H-indol-1-yl)(4-(trifluoromethyl)phenyl)methanone::CHEMBL502966 Fructose-1,6-bisphosphatase 1 Mus musculus 3090 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266599&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 44156953 104113890 CHEMBL502966 ZINC40834891 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447733 CCOC(=O)CC(O)(c1[nH]c(C)cc1C)C(F)(F)F InChI=1S/C12H16F3NO3/c1-4-19-9(17)6-11(18,12(13,14)15)10-7(2)5-8(3)16-10/h5,16,18H,4,6H2,1-3H3 JXCZTWRGVDJILF-UHFFFAOYSA-N 50266600 CHEMBL476823::ethyl 3-(3,5-dimethyl-1H-pyrrol-2-yl)-4,4,4-trifluoro-3-hydroxybutanoate Fructose-1,6-bisphosphatase 1 Mus musculus 4810 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266600&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 23237343 104113891 CHEMBL476823 ZINC40916326 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447734 FC(F)(F)c1cccc(c1)-n1nc(cc1-c1ccccc1)-c1ccccc1 InChI=1S/C22H15F3N2/c23-22(24,25)18-12-7-13-19(14-18)27-21(17-10-5-2-6-11-17)15-20(26-27)16-8-3-1-4-9-16/h1-15H AUYTYBXOQNJIFH-UHFFFAOYSA-N 50266610 3,5-diphenyl-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole::CHEMBL477856 Fructose-1,6-bisphosphatase 1 Mus musculus 6040 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266610&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 44582009 104113893 CHEMBL477856 ZINC40918050 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447735 CCOC(=O)C(O)(c1cn(C)c2ccccc12)C(F)(F)F InChI=1S/C14H14F3NO3/c1-3-21-12(19)13(20,14(15,16)17)10-8-18(2)11-7-5-4-6-9(10)11/h4-8,20H,3H2,1-2H3 DEJAANIXKYEQND-UHFFFAOYSA-N 50266611 CHEMBL505293::ethyl 3,3,3-trifluoro-2-hydroxy-2-(1-methyl-1H-indol-3-yl)propanoate Fructose-1,6-bisphosphatase 1 Mus musculus 11860 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266611&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 3243569 104113894 CHEMBL505293 ZINC03653153 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447736 CCOC(=O)C(O)(c1c[nH]c2ccc(I)cc12)C(F)(F)F InChI=1S/C13H11F3INO3/c1-2-21-11(19)12(20,13(14,15)16)9-6-18-10-4-3-7(17)5-8(9)10/h3-6,18,20H,2H2,1H3 BEDWMXUFZPWAOL-UHFFFAOYSA-N 50266612 CHEMBL446872::ethyl 3,3,3-trifluoro-2-hydroxy-2-(5-iodo-1H-indol-3-yl)propanoate Fructose-1,6-bisphosphatase 1 Mus musculus 13330 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266612&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 23237326 104113895 CHEMBL446872 ZINC40980828 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447737 CCOC(=O)CC(O)(c1ccc[nH]1)C(F)(F)F InChI=1S/C10H12F3NO3/c1-2-17-8(15)6-9(16,10(11,12)13)7-4-3-5-14-7/h3-5,14,16H,2,6H2,1H3 MLWNIZLFGXOZEU-UHFFFAOYSA-N 50266613 CHEMBL517208::ethyl 4,4,4-trifluoro-3-hydroxy-3-(1H-pyrrol-2-yl)butanoate Fructose-1,6-bisphosphatase 1 Mus musculus 25740 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266613&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 23237341 104113896 CHEMBL517208 ZINC40405437 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447738 CCOC(=O)C(O)(c1ccc[nH]1)C(F)(F)F InChI=1S/C9H10F3NO3/c1-2-16-7(14)8(15,9(10,11)12)6-4-3-5-13-6/h3-5,13,15H,2H2,1H3 ZOQFCCWJBVOJKD-UHFFFAOYSA-N 50266614 CHEMBL503725::ethyl 3,3,3-trifluoro-2-hydroxy-2-(1H-pyrrol-2-yl)propanoate Fructose-1,6-bisphosphatase 1 Mus musculus 25740 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266614&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 11651605 104113897 CHEMBL503725 ZINC40828768 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447739 CCOC(=O)C(O)(c1c[nH]c2ccc(C)cc12)C(F)(F)F InChI=1S/C14H14F3NO3/c1-3-21-12(19)13(20,14(15,16)17)10-7-18-11-5-4-8(2)6-9(10)11/h4-7,18,20H,3H2,1-2H3 BZHHCFFYWDIFEI-UHFFFAOYSA-N 50266615 CHEMBL517655::ethyl 3,3,3-trifluoro-2-hydroxy-2-(5-methyl-1H-indol-3-yl)propanoate Fructose-1,6-bisphosphatase 1 Mus musculus 35970 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266615&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 23237325 104113898 CHEMBL517655 ZINC40406711 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447740 CCOC(=O)CC(O)(c1cccn1C)C(F)(F)F InChI=1S/C11H14F3NO3/c1-3-18-9(16)7-10(17,11(12,13)14)8-5-4-6-15(8)2/h4-6,17H,3,7H2,1-2H3 RQYXKPAZAREWOU-UHFFFAOYSA-N 50266616 CHEMBL505221::ethyl 4,4,4-trifluoro-3-hydroxy-3-(1-methyl-1H-pyrrol-2-yl)butanoate Fructose-1,6-bisphosphatase 1 Mus musculus 41790 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266616&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 23237342 104113899 CHEMBL505221 ZINC40379013 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447741 Fc1ccc(cc1)-c1cc(-c2ccc(F)cc2)n(n1)-c1cccc(c1)C(F)(F)F InChI=1S/C22H13F5N2/c23-17-8-4-14(5-9-17)20-13-21(15-6-10-18(24)11-7-15)29(28-20)19-3-1-2-16(12-19)22(25,26)27/h1-13H LXOVAVCSRGJJCE-UHFFFAOYSA-N 50266634 3,5-bis(4-fluorophenyl)-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole::CHEMBL476015 Fructose-1,6-bisphosphatase 1 Mus musculus 75450 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266634&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 44582017 104113904 CHEMBL476015 ZINC40405410 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447742 O=S(=O)(c1ccccc1)n1cccc1 InChI=1S/C10H9NO2S/c12-14(13,11-8-4-5-9-11)10-6-2-1-3-7-10/h1-9H PPPXRIUHKCOOMU-UHFFFAOYSA-N 50266635 1-(phenylsulfonyl)-1H-pyrrole::CHEMBL449256 Fructose-1,6-bisphosphatase 1 Mus musculus 76150 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266635&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 140146 104113905 CHEMBL449256 ZINC00092362 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447743 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)n1cccc1 InChI=1S/C10H8N2O4S/c13-12(14)9-3-5-10(6-4-9)17(15,16)11-7-1-2-8-11/h1-8H XQLYKJOAKINWEF-UHFFFAOYSA-N 50266636 1-(4-nitrophenylsulfonyl)-1H-pyrrole::CHEMBL446206 Fructose-1,6-bisphosphatase 1 Mus musculus 109030 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266636&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 265691 104113906 CHEMBL446206 ZINC01674533 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447744 O=S(=O)(c1ccccc1)n1ccc2ccccc12 InChI=1S/C14H11NO2S/c16-18(17,13-7-2-1-3-8-13)15-11-10-12-6-4-5-9-14(12)15/h1-11H VDWLCYCWLIKWBV-UHFFFAOYSA-N 50187508 1-(phenylsulfonyl)-1H-indole::1-Benzenesulfonyl-1H-indole::1-Phenylsulfonyl-1H-indole::CHEMBL82224 Fructose-1,6-bisphosphatase 1 Mus musculus 119260 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187508&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 315017 104071428 CHEMBL82224 ZINC00142373 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447745 Fc1ccc(cc1)C(=O)n1ccc2ccccc12 InChI=1S/C15H10FNO/c16-13-7-5-12(6-8-13)15(18)17-10-9-11-3-1-2-4-14(11)17/h1-10H YRAMSNKAQXFABP-UHFFFAOYSA-N 50266637 (4-fluorophenyl)(1H-indol-1-yl)methanone::CHEMBL479097 Fructose-1,6-bisphosphatase 1 Mus musculus 129430 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266637&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 44582018 104113907 CHEMBL479097 ZINC40918249 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447746 Fc1ccc(cc1)-c1cc(-c2ccc(F)cc2)n(n1)-c1ccccc1 InChI=1S/C21H14F2N2/c22-17-10-6-15(7-11-17)20-14-21(16-8-12-18(23)13-9-16)25(24-20)19-4-2-1-3-5-19/h1-14H SDRKZTNENZLOBY-UHFFFAOYSA-N 50266638 3,5-bis(4-fluorophenyl)-1-phenyl-1H-pyrazole::CHEMBL479098 Fructose-1,6-bisphosphatase 1 Mus musculus 150600 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266638&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 10711613 104113908 CHEMBL479098 ZINC17068213 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447747 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)n1c2ccccc2c2ccccc12 InChI=1S/C18H12N2O4S/c21-20(22)13-9-11-14(12-10-13)25(23,24)19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-12H MXQSTURKDCSFOO-UHFFFAOYSA-N 50266655 9-(4-nitrophenylsulfonyl)-9H-carbazole::CHEMBL475970 Fructose-1,6-bisphosphatase 1 Mus musculus 176980 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266655&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 16723305 104113911 CHEMBL475970 ZINC40918260 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447748 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)n1ccc2ccccc12 InChI=1S/C14H10N2O4S/c17-16(18)12-5-7-13(8-6-12)21(19,20)15-10-9-11-3-1-2-4-14(11)15/h1-10H XJLBMIXVBVSLOP-UHFFFAOYSA-N 50266656 1-(4-nitrophenylsulfonyl)-1H-indole::CHEMBL517496 Fructose-1,6-bisphosphatase 1 Mus musculus 184950 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266656&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 16070995 104113912 CHEMBL517496 ZINC34998865 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447749 COc1ccc(cc1)S(=O)(=O)n1cccc1 InChI=1S/C11H11NO3S/c1-15-10-4-6-11(7-5-10)16(13,14)12-8-2-3-9-12/h2-9H,1H3 PTOXNAYXGVJKDN-UHFFFAOYSA-N 50266657 1-(4-methoxyphenylsulfonyl)-1H-pyrrole::CHEMBL504254 Fructose-1,6-bisphosphatase 1 Mus musculus 245600 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266657&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 831626 104113913 CHEMBL504254 ZINC00355429 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447750 COc1ccc(cc1)S(=O)(=O)n1c2ccccc2c2ccccc12 InChI=1S/C19H15NO3S/c1-23-14-10-12-15(13-11-14)24(21,22)20-18-8-4-2-6-16(18)17-7-3-5-9-19(17)20/h2-13H,1H3 SVIIMJJDMQMTAD-UHFFFAOYSA-N 50266658 9-(4-methoxyphenylsulfonyl)-9H-carbazole::CHEMBL475971 Fructose-1,6-bisphosphatase 1 Mus musculus >250000 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266658&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 44582029 104113914 CHEMBL475971 ZINC40918261 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447751 Cc1ccccc1S(=O)(=O)n1cccc1 InChI=1S/C11H11NO2S/c1-10-6-2-3-7-11(10)15(13,14)12-8-4-5-9-12/h2-9H,1H3 OQNWLRHMYVSMSJ-UHFFFAOYSA-N 50266659 1-(o-tolylsulfonyl)-1H-pyrrole::CHEMBL517497 Fructose-1,6-bisphosphatase 1 Mus musculus >250000 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266659&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 44582030 104113915 CHEMBL517497 ZINC40404579 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447752 COc1ccc(cc1)S(=O)(=O)n1ccc2ccccc12 InChI=1S/C15H13NO3S/c1-19-13-6-8-14(9-7-13)20(17,18)16-11-10-12-4-2-3-5-15(12)16/h2-11H,1H3 TVTFKGKDSMJQEF-UHFFFAOYSA-N 50266660 1-(4-methoxyphenylsulfonyl)-1H-indole::CHEMBL476177 Fructose-1,6-bisphosphatase 1 Mus musculus >300000 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266660&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 11243165 104113916 CHEMBL476177 ZINC40917189 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447753 [O-][N+](=O)c1ccc(cc1)C(=O)n1ccc2ccccc12 InChI=1S/C15H10N2O3/c18-15(12-5-7-13(8-6-12)17(19)20)16-10-9-11-3-1-2-4-14(11)16/h1-10H DGDZMLHVARJZHR-UHFFFAOYSA-N 50266661 (1H-indol-1-yl)(4-nitrophenyl)methanone::CHEMBL518577 Fructose-1,6-bisphosphatase 1 Mus musculus >300000 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266661&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24813796 104113917 CHEMBL518577 ZINC40409331 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447754 [O-][N+](=O)c1ccc(cc1)-n1nc(cc1-c1ccccc1)-c1ccccc1 InChI=1S/C21H15N3O2/c25-24(26)19-13-11-18(12-14-19)23-21(17-9-5-2-6-10-17)15-20(22-23)16-7-3-1-4-8-16/h1-15H PXCMBYXFVRQYSH-UHFFFAOYSA-N 50266682 1-(4-nitrophenyl)-3,5-diphenyl-1H-pyrazole::CHEMBL477837 Fructose-1,6-bisphosphatase 1 Mus musculus >300000 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266682&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 680475 104113921 CHEMBL477837 ZINC00045072 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447755 O=S(=O)(c1ccc2ccccc2c1)n1ccc2ccccc12 InChI=1S/C18H13NO2S/c20-22(21,19-12-11-15-6-3-4-8-18(15)19)17-10-9-14-5-1-2-7-16(14)13-17/h1-13H OQXCDXOFSOQVFD-UHFFFAOYSA-N 50266683 1-(naphthalen-2-ylsulfonyl)-1H-indole::CHEMBL477838::cid_10590848 Fructose-1,6-bisphosphatase 1 Mus musculus >300000 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266683&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 10590848 104113922 CHEMBL477838 ZINC39047201 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447756 O=S(=O)(c1ccc2ccccc2c1)n1c2ccccc2c2ccccc12 InChI=1S/C22H15NO2S/c24-26(25,18-14-13-16-7-1-2-8-17(16)15-18)23-21-11-5-3-9-19(21)20-10-4-6-12-22(20)23/h1-15H OGWRCTVGMJBFRL-UHFFFAOYSA-N 50266684 9-(naphthalen-2-ylsulfonyl)-9H-carbazole::CHEMBL517206 Fructose-1,6-bisphosphatase 1 Mus musculus >300000 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266684&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 10618316 104113923 CHEMBL517206 ZINC39095046 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447757 COC(=O)c1ccc2[nH]c3ccccc3c2c1 InChI=1S/C14H11NO2/c1-17-14(16)9-6-7-13-11(8-9)10-4-2-3-5-12(10)15-13/h2-8,15H,1H3 LZXXHWWSVRIDGR-UHFFFAOYSA-N 50259669 CHEMBL446253::methyl 9H-carbazole-3-carboxylate::methyl carbazole-3-carboxylate Fructose-1,6-bisphosphatase 1 Mus musculus >300000 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259669&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 504069 104109881 CHEMBL446253 ZINC03641060 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447758 COc1ccc2[nH]c3c(C)ccc(C)c3c2c1 InChI=1S/C15H15NO/c1-9-4-5-10(2)15-14(9)12-8-11(17-3)6-7-13(12)16-15/h4-8,16H,1-3H3 JYCYJKQLGQKTRX-UHFFFAOYSA-N 50266685 6-methoxy-1,4-dimethyl-9H-carbazole::CHEMBL477756 Fructose-1,6-bisphosphatase 1 Mus musculus >300000 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266685&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 87416 104113924 CHEMBL477756 ZINC04089483 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50447759 Cc1ccc(cc1)S(=O)(=O)n1cccc1 InChI=1S/C11H11NO2S/c1-10-4-6-11(7-5-10)15(13,14)12-8-2-3-9-12/h2-9H,1H3 OXWIEWFMRVJGNY-UHFFFAOYSA-N 50266686 1-tosyl-1H-pyrrole::1-tosyl-pyrrole::CA inhibitor, 13::CHEMBL508732 Fructose-1,6-bisphosphatase 1 Mus musculus >300000 ChEMBL 10.1021/jm800720a 10.7270/Q2JQ10WV 19143528 Rudnitskaya, A; Huynh, K; Torok, B; Stieglitz, K University of Massachusetts http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266686&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 640087 104113925 CHEMBL508732 ZINC00403153 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547494 CCc1cc(ccc1-c1ccccc1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C18H16BrN3O3S2/c1-2-12-10-14(8-9-15(12)13-6-4-3-5-7-13)27(24,25)22-17(23)21-18-20-11-16(19)26-18/h3-11H,2H2,1H3,(H2,20,21,22,23) NUXUEZJTLCTLKE-UHFFFAOYSA-N 50305556 CHEMBL595529::N-(5-bromothiazol-2-ylcarbamoyl)-2-ethylbiphenyl-4-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 63000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305556&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 947 5PZT 24752079 104159917 CHEMBL595529 ZINC45350109 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547497 Cc1cc(ccc1-c1ccc(F)nc1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C16H12BrFN4O3S2/c1-9-6-11(3-4-12(9)10-2-5-14(18)19-7-10)27(24,25)22-15(23)21-16-20-8-13(17)26-16/h2-8H,1H3,(H2,20,21,22,23) MGILTQRFNXGDIM-UHFFFAOYSA-N 50305557 CHEMBL611631::N-(5-bromothiazol-2-ylcarbamoyl)-4-(6-fluoropyridin-3-yl)-3-methylbenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 10000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305557&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752505 104159918 CHEMBL611631 ZINC45394399 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547500 COc1nc(cs1)-c1ccc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C15H13BrN4O4S3/c1-8-5-9(3-4-10(8)11-7-25-15(18-11)24-2)27(22,23)20-13(21)19-14-17-6-12(16)26-14/h3-7H,1-2H3,(H2,17,19,20,21) VBEKOCDGOZPIRV-UHFFFAOYSA-N 50305558 CHEMBL594444::N-(5-bromothiazol-2-ylcarbamoyl)-4-(2-methoxythiazol-4-yl)-3-methylbenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 62000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305558&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752646 104159919 CHEMBL594444 ZINC45349452 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547503 Clc1ccc(s1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C8H5BrClN3O3S3/c9-4-3-11-8(17-4)12-7(14)13-19(15,16)6-2-1-5(10)18-6/h1-3H,(H2,11,12,13,14) LGWYGKDXWKKKBD-UHFFFAOYSA-N 50305559 CHEMBL594445::N-(5-bromothiazol-2-ylcarbamoyl)-5-chlorothiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 92000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305559&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24751659 104159920 CHEMBL594445 ZINC45349455 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547506 Clc1sc(cc1Br)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C8H4Br2ClN3O3S3/c9-3-1-5(19-6(3)11)20(16,17)14-7(15)13-8-12-2-4(10)18-8/h1-2H,(H2,12,13,14,15) KCDHTUJNBLJXDX-UHFFFAOYSA-N 50305560 4-bromo-N-(5-bromothiazol-2-ylcarbamoyl)-5-chlorothiophene-2-sulfonamide::CHEMBL610462 Fructose-1,6-bisphosphatase 1 Mus musculus 87000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305560&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 95P 5Q04 24752361 104159921 CHEMBL610462 ZINC45393467 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547509 COc1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C10H10BrN3O4S3/c1-5-3-7(20-8(5)18-2)21(16,17)14-9(15)13-10-12-4-6(11)19-10/h3-4H,1-2H3,(H2,12,13,14,15) CSJISBZQKAOPMI-UHFFFAOYSA-N 50305561 CHEMBL593282::N-(5-bromothiazol-2-ylcarbamoyl)-5-methoxy-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 24000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305561&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752648 104159922 CHEMBL593282 ZINC45349793 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547512 CC(C)Cc1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C13H16BrN3O3S3/c1-7(2)4-9-8(3)5-11(21-9)23(19,20)17-12(18)16-13-15-6-10(14)22-13/h5-7H,4H2,1-3H3,(H2,15,16,17,18) PUQFGUSERAJQFU-UHFFFAOYSA-N 50305562 CHEMBL590359::N-(5-bromothiazol-2-ylcarbamoyl)-5-isobutyl-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 13000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305562&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752507 104159923 CHEMBL590359 ZINC45335717 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547515 COCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C11H12BrN3O4S3/c1-6-3-9(20-7(6)5-19-2)22(17,18)15-10(16)14-11-13-4-8(12)21-11/h3-4H,5H2,1-2H3,(H2,13,14,15,16) TXHZITANBAJZEM-UHFFFAOYSA-N 50305563 CHEMBL590360::N-(5-bromothiazol-2-ylcarbamoyl)-5-(methoxymethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 10000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305563&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752788 104159924 CHEMBL590360 ZINC45336011 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547517 Cc1cc(sc1CO)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C10H10BrN3O4S3/c1-5-2-8(19-6(5)4-15)21(17,18)14-9(16)13-10-12-3-7(11)20-10/h2-3,15H,4H2,1H3,(H2,12,13,14,16) SGGATSCESGSKQF-UHFFFAOYSA-N 50305564 CHEMBL600653::N-(5-bromothiazol-2-ylcarbamoyl)-5-(hydroxymethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 42000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305564&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 46224737 104159925 CHEMBL600653 ZINC45368224 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547520 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C12H14BrN3O4S3/c1-7-5-10(21-8(7)3-4-20-2)23(18,19)16-11(17)15-12-14-6-9(13)22-12/h5-6H,3-4H2,1-2H3,(H2,14,15,16,17) GYLXXAGXBDRUHI-UHFFFAOYSA-N 50305565 CHEMBL590361::N-(5-bromothiazol-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 5500 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305565&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 95S 5Q05 24752506 104159926 CHEMBL590361 ZINC45336014 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547523 Brc1cnc(NC(=O)NS(=O)(=O)c2cc3COCCc3s2)s1 InChI=1S/C11H10BrN3O4S3/c12-8-4-13-11(21-8)14-10(16)15-22(17,18)9-3-6-5-19-2-1-7(6)20-9/h3-4H,1-2,5H2,(H2,13,14,15,16) WGBGKFSPGAVVBQ-UHFFFAOYSA-N 50305566 CHEMBL585961::N-(5-bromothiazol-2-ylcarbamoyl)-6,7-dihydro-4H-thieno[3,2-c]pyran-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 27000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305566&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 46224738 104159927 CHEMBL585961 ZINC45335286 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547526 COCCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C13H16BrN3O4S3/c1-8-6-11(22-9(8)4-3-5-21-2)24(19,20)17-12(18)16-13-15-7-10(14)23-13/h6-7H,3-5H2,1-2H3,(H2,15,16,17,18) JDPUXQSKWRFVOE-UHFFFAOYSA-N 50305567 CHEMBL589863::N-(5-bromothiazol-2-ylcarbamoyl)-5-(3-methoxypropyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 3200 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305567&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24780311 104159928 CHEMBL589863 ZINC45336330 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547529 COCCOc1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C12H14BrN3O5S3/c1-7-5-9(23-10(7)21-4-3-20-2)24(18,19)16-11(17)15-12-14-6-8(13)22-12/h5-6H,3-4H2,1-2H3,(H2,14,15,16,17) QDNFPGPYDSKNSC-UHFFFAOYSA-N 50305568 CHEMBL585620::N-(5-bromothiazol-2-ylcarbamoyl)-5-(2-methoxyethoxy)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 12000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305568&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752786 104159929 CHEMBL585620 ZINC45325015 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547532 COc1ccc(-c2sc(cc2C)S(=O)(=O)NC(=O)Nc2ncc(Br)s2)c(C)c1 InChI=1S/C17H16BrN3O4S3/c1-9-6-11(25-3)4-5-12(9)15-10(2)7-14(27-15)28(23,24)21-16(22)20-17-19-8-13(18)26-17/h4-8H,1-3H3,(H2,19,20,21,22) KCBMMYUZSJZEEC-UHFFFAOYSA-N 50305569 CHEMBL590597::N-(5-bromothiazol-2-ylcarbamoyl)-5-(4-methoxy-2-methylphenyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 19000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305569&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752643 104159930 CHEMBL590597 ZINC45335411 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547535 COc1ccc(cn1)-c1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C15H13BrN4O4S3/c1-8-5-12(26-13(8)9-3-4-11(24-2)17-6-9)27(22,23)20-14(21)19-15-18-7-10(16)25-15/h3-7H,1-2H3,(H2,18,19,20,21) TUQAZFRFRVHOMZ-UHFFFAOYSA-N 50305570 CHEMBL589865::N-(5-bromothiazol-2-ylcarbamoyl)-5-(6-methoxypyridin-3-yl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 34000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305570&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752645 104159931 CHEMBL589865 ZINC45336605 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547538 COc1cc(C)c(cn1)-c1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C16H15BrN4O4S3/c1-8-4-12(25-3)18-6-10(8)14-9(2)5-13(27-14)28(23,24)21-15(22)20-16-19-7-11(17)26-16/h4-7H,1-3H3,(H2,19,20,21,22) SCYQEBQFJHOUOV-UHFFFAOYSA-N 50305571 CHEMBL601691::N-(5-bromothiazol-2-ylcarbamoyl)-5-(6-methoxy-4-methylpyridin-3-yl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 9000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305571&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752787 104159932 CHEMBL601691 ZINC45367986 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547541 Cc1cc(sc1-c1ccc(F)nc1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C14H10BrFN4O3S3/c1-7-4-11(25-12(7)8-2-3-10(16)17-5-8)26(22,23)20-13(21)19-14-18-6-9(15)24-14/h2-6H,1H3,(H2,18,19,20,21) GFHDZJKEYHPWMJ-UHFFFAOYSA-N 50305572 CHEMBL590111::N-(5-bromothiazol-2-ylcarbamoyl)-5-(6-fluoropyridin-3-yl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 9000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305572&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24780310 104159933 CHEMBL590111 ZINC45336340 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547544 Cc1ccc2sc(cc2c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C13H10BrN3O3S3/c1-7-2-3-9-8(4-7)5-11(21-9)23(19,20)17-12(18)16-13-15-6-10(14)22-13/h2-6H,1H3,(H2,15,16,17,18) VUJCDWNPYWBSJU-UHFFFAOYSA-N 50305573 CHEMBL590839::N-(5-bromothiazol-2-ylcarbamoyl)-5-methylbenzo[b]thiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 18000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305573&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42634696 104159934 CHEMBL590839 ZINC45335429 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547547 Cn1cc(c2ccccc12)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C13H11BrN4O3S2/c1-18-7-10(8-4-2-3-5-9(8)18)23(20,21)17-12(19)16-13-15-6-11(14)22-13/h2-7H,1H3,(H2,15,16,17,19) NPDQVMSMJHIPDQ-UHFFFAOYSA-N 50305574 CHEMBL590840::N-(5-bromothiazol-2-ylcarbamoyl)-1-methyl-1H-indole-3-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 14000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305574&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42635072 104159935 CHEMBL590840 ZINC45335431 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547549 COc1cccc2c(cn(C)c12)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C14H13BrN4O4S2/c1-19-7-10(8-4-3-5-9(23-2)12(8)19)25(21,22)18-13(20)17-14-16-6-11(15)24-14/h3-7H,1-2H3,(H2,16,17,18,20) UYENKFIAVMJNOD-UHFFFAOYSA-N 50305575 CHEMBL590113::N-(5-bromothiazol-2-ylcarbamoyl)-7-methoxy-1-methyl-1H-indole-3-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 14000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305575&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42635430 104159936 CHEMBL590113 ZINC45336346 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547551 Cn1cc(c2cccc(OCCO)c12)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C15H15BrN4O5S2/c1-20-8-11(9-3-2-4-10(13(9)20)25-6-5-21)27(23,24)19-14(22)18-15-17-7-12(16)26-15/h2-4,7-8,21H,5-6H2,1H3,(H2,17,18,19,22) DVSJWUQOJNQBRA-UHFFFAOYSA-N 50305576 CHEMBL601267::N-(5-bromothiazol-2-ylcarbamoyl)-7-(2-hydroxyethoxy)-1-methyl-1H-indole-3-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 6300 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305576&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42635792 104159937 CHEMBL601267 ZINC45371129 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547553 Cc1nc(NC(=O)NS(=O)(=O)c2cccc(OC(F)F)c2)sc1Br InChI=1S/C12H10BrF2N3O4S2/c1-6-9(13)23-12(16-6)17-11(19)18-24(20,21)8-4-2-3-7(5-8)22-10(14)15/h2-5,10H,1H3,(H2,16,17,18,19) DXBZEWFGCOOOEV-UHFFFAOYSA-N 50305577 CHEMBL590362::N-(5-bromo-4-methylthiazol-2-ylcarbamoyl)-3-(difluoromethoxy)benzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 14000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305577&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752790 104159938 CHEMBL590362 ZINC45336018 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547555 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1ncc(SC)s1 InChI=1S/C13H17N3O4S4/c1-8-6-11(22-9(8)4-5-20-2)24(18,19)16-12(17)15-13-14-7-10(21-3)23-13/h6-7H,4-5H2,1-3H3,(H2,14,15,16,17) UMTVKAYORCMVTN-UHFFFAOYSA-N 50305578 5-(2-methoxyethyl)-4-methyl-N-(5-(methylthio)thiazol-2-ylcarbamoyl)thiophene-2-sulfonamide::CHEMBL573056 Fructose-1,6-bisphosphatase 1 Mus musculus 6500 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305578&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 46224826 104159939 CHEMBL573056 ZINC45287007 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547557 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1nc(C)c(SC)s1 InChI=1S/C14H19N3O4S4/c1-8-7-11(23-10(8)5-6-21-3)25(19,20)17-13(18)16-14-15-9(2)12(22-4)24-14/h7H,5-6H2,1-4H3,(H2,15,16,17,18) LEQXJKNARKRTBG-UHFFFAOYSA-N 50305579 5-(2-methoxyethyl)-4-methyl-N-(4-methyl-5-(methylthio)thiazol-2-ylcarbamoyl)thiophene-2-sulfonamide::CHEMBL591083 Fructose-1,6-bisphosphatase 1 Mus musculus 2400 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305579&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 46224868 104159940 CHEMBL591083 ZINC45335752 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547559 CSc1sc(NC(=O)NS(=O)(=O)c2cc(C)c(CCO)s2)nc1C InChI=1S/C13H17N3O4S4/c1-7-6-10(22-9(7)4-5-17)24(19,20)16-12(18)15-13-14-8(2)11(21-3)23-13/h6,17H,4-5H2,1-3H3,(H2,14,15,16,18) DWNWDKRMRCFDSY-UHFFFAOYSA-N 50305580 5-(2-hydroxyethyl)-4-methyl-N-(4-methyl-5-(methylthio)thiazol-2-ylcarbamoyl)thiophene-2-sulfonamide::CHEMBL605615 Fructose-1,6-bisphosphatase 1 Mus musculus 2800 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305580&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42634015 104159941 CHEMBL605615 ZINC45391704 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547561 CCc1nc(NC(=O)NS(=O)(=O)c2cc(C)c(CCO)s2)sc1SC InChI=1S/C14H19N3O4S4/c1-4-9-12(22-3)24-14(15-9)16-13(19)17-25(20,21)11-7-8(2)10(23-11)5-6-18/h7,18H,4-6H2,1-3H3,(H2,15,16,17,19) GOMWXNSWFQGART-UHFFFAOYSA-N 50305581 CHEMBL590363::N-(4-ethyl-5-(methylthio)thiazol-2-ylcarbamoyl)-5-(2-hydroxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 5300 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305581&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42634013 104159942 CHEMBL590363 ZINC45336021 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547563 CCc1nc(NC(=O)NS(=O)(=O)c2cc(C)c(CCO)s2)sc1OC InChI=1S/C14H19N3O5S3/c1-4-9-12(22-3)24-14(15-9)16-13(19)17-25(20,21)11-7-8(2)10(23-11)5-6-18/h7,18H,4-6H2,1-3H3,(H2,15,16,17,19) RDOOMXMPQGODOC-UHFFFAOYSA-N 50305582 CHEMBL602789::N-(4-ethyl-5-methoxythiazol-2-ylcarbamoyl)-5-(2-hydroxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 9200 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305582&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 46224869 104159943 CHEMBL602789 ZINC45371827 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547569 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C11H10BrN3O3S2/c1-7-2-4-8(5-3-7)20(17,18)15-10(16)14-11-13-6-9(12)19-11/h2-6H,1H3,(H2,13,14,15,16) XFLQMYNYRPUILJ-UHFFFAOYSA-N 50305584 CHEMBL595067::N-(5-bromothiazol-2-ylcarbamoyl)-4-methylbenzenesulfonamide::N-{[(2Z)-5-BROMO-1,3-THIAZOL-2(3H)-YLIDENE]CARBAMOYL}-4-METHYLBENZENESULFONAMIDE Fructose-1,6-bisphosphatase 1 Mus musculus 118000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305584&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24751933 104159945 CHEMBL595067 ZINC45339707 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547572 Cc1cccc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C11H10BrN3O3S2/c1-7-3-2-4-8(5-7)20(17,18)15-10(16)14-11-13-6-9(12)19-11/h2-6H,1H3,(H2,13,14,15,16) UGGXZOFPTPJQCH-UHFFFAOYSA-N 50305585 CHEMBL589861::N-(5-bromothiazol-2-ylcarbamoyl)-3-methylbenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 23000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305585&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752501 104159946 CHEMBL589861 ZINC43176016 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547575 Cc1cc(C)cc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C12H12BrN3O3S2/c1-7-3-8(2)5-9(4-7)21(18,19)16-11(17)15-12-14-6-10(13)20-12/h3-6H,1-2H3,(H2,14,15,16,17) BQEKEXJQGDNDDF-UHFFFAOYSA-N 50305586 CHEMBL589862::N-(5-bromothiazol-2-ylcarbamoyl)-3,5-dimethylbenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 19000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305586&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24751654 104159947 CHEMBL589862 ZINC45336327 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547578 CCc1cccc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C12H12BrN3O3S2/c1-2-8-4-3-5-9(6-8)21(18,19)16-11(17)15-12-14-7-10(13)20-12/h3-7H,2H2,1H3,(H2,14,15,16,17) CDARLLLKPJHKBU-UHFFFAOYSA-N 50305587 CHEMBL589137::N-(5-bromothiazol-2-ylcarbamoyl)-3-ethylbenzenesulfonamide::N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-3-ethylbenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 32000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305587&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search RO5 2WBD 24752215 104159948 CHEMBL589137 ZINC45339545 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547581 Cc1ccccc1S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C11H10BrN3O3S2/c1-7-4-2-3-5-8(7)20(17,18)15-10(16)14-11-13-6-9(12)19-11/h2-6H,1H3,(H2,13,14,15,16) XOUHCSDCASEPBI-UHFFFAOYSA-N 50305588 CHEMBL607540::N-(5-bromothiazol-2-ylcarbamoyl)-2-methylbenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus >100000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305588&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 46225257 104159949 CHEMBL607540 ZINC45390035 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547584 Clc1cccc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C10H7BrClN3O3S2/c11-8-5-13-10(19-8)14-9(16)15-20(17,18)7-3-1-2-6(12)4-7/h1-5H,(H2,13,14,15,16) VRHXEPNJEQXSSS-UHFFFAOYSA-N 50305589 CHEMBL595149::N-(5-bromothiazol-2-ylcarbamoyl)-3-chlorobenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 49000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305589&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24780158 104159950 CHEMBL595149 ZINC45348530 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547587 FC(F)Oc1cccc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C11H8BrF2N3O4S2/c12-8-5-15-11(22-8)16-10(18)17-23(19,20)7-3-1-2-6(4-7)21-9(13)14/h1-5,9H,(H2,15,16,17,18) CSQRTNQHFALVNU-UHFFFAOYSA-N 50305590 CHEMBL595150::N-(5-bromothiazol-2-ylcarbamoyl)-3-(difluoromethoxy)benzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 24000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305590&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752360 104159951 CHEMBL595150 ZINC45348532 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547590 FC(F)(F)Oc1cccc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C11H7BrF3N3O4S2/c12-8-5-16-10(23-8)17-9(19)18-24(20,21)7-3-1-2-6(4-7)22-11(13,14)15/h1-5H,(H2,16,17,18,19) VJVHUPIOHBGTKO-UHFFFAOYSA-N 50305591 CHEMBL594668::N-(5-bromothiazol-2-ylcarbamoyl)-3-(trifluoromethoxy)benzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus >100000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305591&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24751937 104159952 CHEMBL594668 ZINC45348471 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547593 CC(C)c1cccc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C13H14BrN3O3S2/c1-8(2)9-4-3-5-10(6-9)22(19,20)17-12(18)16-13-15-7-11(14)21-13/h3-8H,1-2H3,(H2,15,16,17,18) AWYTUEYYWYQHLN-UHFFFAOYSA-N 50305592 CHEMBL608398::N-(5-bromothiazol-2-ylcarbamoyl)-3-isopropylbenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 74000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305592&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24752216 104159953 CHEMBL608398 ZINC45391302 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547596 Nc1cccc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C10H9BrN4O3S2/c11-8-5-13-10(19-8)14-9(16)15-20(17,18)7-3-1-2-6(12)4-7/h1-5H,12H2,(H2,13,14,15,16) ADIMXNMWUQPSQV-UHFFFAOYSA-N 50305593 3-amino-N-(5-bromothiazol-2-ylcarbamoyl)benzenesulfonamide::CHEMBL595304 Fructose-1,6-bisphosphatase 1 Mus musculus >100000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305593&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 46225258 104159954 CHEMBL595304 ZINC45349091 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547599 CCc1sc(NC(=O)NS(=O)(=O)c2cc(C)c(CCO)s2)nc1C InChI=1S/C14H19N3O4S3/c1-4-10-9(3)15-14(23-10)16-13(19)17-24(20,21)12-7-8(2)11(22-12)5-6-18/h7,18H,4-6H2,1-3H3,(H2,15,16,17,19) CKPJEUJAVPSMCJ-UHFFFAOYSA-N 50305583 CHEMBL600654::N-(5-ethyl-4-methylthiazol-2-ylcarbamoyl)-5-(2-hydroxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 8100 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305583&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42633650 104159944 CHEMBL600654 ZINC45368227 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547601 Cc1cc(sc1CCO)S(=O)(=O)NC(=O)Nc1nc(C)c(s1)C(F)(F)F InChI=1S/C13H14F3N3O4S3/c1-6-5-9(24-8(6)3-4-20)26(22,23)19-11(21)18-12-17-7(2)10(25-12)13(14,15)16/h5,20H,3-4H2,1-2H3,(H2,17,18,19,21) ZKVIJKYNMDZJOU-UHFFFAOYSA-N 50305594 5-(2-hydroxyethyl)-4-methyl-N-(4-methyl-5-(trifluoromethyl)thiazol-2-ylcarbamoyl)thiophene-2-sulfonamide::CHEMBL591316 Fructose-1,6-bisphosphatase 1 Mus musculus 10000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305594&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 46224902 104159955 CHEMBL591316 ZINC45336087 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50547603 COc1ccc(Cl)c2sc(NC(=O)NS(=O)(=O)c3cc(C)c(CCO)s3)nc12 InChI=1S/C16H16ClN3O5S3/c1-8-7-12(26-11(8)5-6-21)28(23,24)20-15(22)19-16-18-13-10(25-2)4-3-9(17)14(13)27-16/h3-4,7,21H,5-6H2,1-2H3,(H2,18,19,20,22) LPRLYQWKGUIHQN-UHFFFAOYSA-N 50305595 CHEMBL591317::N-(7-chloro-4-methoxybenzo[d]thiazol-2-ylcarbamoyl)-5-(2-hydroxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 15000 ChEMBL 10.1016/j.bmcl.2009.11.093 10.7270/Q27H1JPX 19969452 Kitas, E; Mohr, P; Kuhn, B; Hebeisen, P; Wessel, HP; Haap, W; Ruf, A; Benz, J; Joseph, C; Huber, W; Sanchez, RA; Paehler, A; Benardeau, A; Gubler, M; Schott, B; Tozzo, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305595&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 46224903 104159956 CHEMBL591317 ZINC45336089 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641657 Clc1cccc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1 InChI=1S/C10H7BrClN3O3S2/c11-8-5-13-10(19-8)14-9(16)15-20(17,18)7-3-1-2-6(12)4-7/h1-5H,(H2,13,14,15,16) VRHXEPNJEQXSSS-UHFFFAOYSA-N 50305589 CHEMBL595149::N-(5-bromothiazol-2-ylcarbamoyl)-3-chlorobenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 5790 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305589&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 24780158 104159950 CHEMBL595149 ZINC45348530 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641658 Clc1cccc(c1)S(=O)(=O)NC(=O)Nc1cc(Cl)cc(Cl)c1 InChI=1S/C13H9Cl3N2O3S/c14-8-2-1-3-12(7-8)22(20,21)18-13(19)17-11-5-9(15)4-10(16)6-11/h1-7H,(H2,17,18,19) WEPSKTYXYPARSQ-UHFFFAOYSA-N 50344563 3-chloro-N-(3,5-dichlorophenylcarbamoyl)benzenesulfonamide::CHEMBL1778441 Fructose-1,6-bisphosphatase 1 Mus musculus 12000 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344563&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 54587610 131347499 CHEMBL1778441 ZINC71341115 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641659 Clc1cccc(c1)S(=O)(=O)NC(=O)Nc1cc(Br)cc2[nH]ccc12 InChI=1S/C15H11BrClN3O3S/c16-9-6-13-12(4-5-18-13)14(7-9)19-15(21)20-24(22,23)11-3-1-2-10(17)8-11/h1-8,18H,(H2,19,20,21) WNEKYDCEAOGJIR-UHFFFAOYSA-N 50344564 CHEMBL1778442::N-(6-bromo-1H-indol-4-ylcarbamoyl)-3-chlorobenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 5000 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344564&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 54587611 131347500 CHEMBL1778442 ZINC71333509 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641660 Clc1cccc(c1)S(=O)(=O)NC(=O)Nc1cc(Br)cc2[nH]ncc12 InChI=1S/C14H10BrClN4O3S/c15-8-4-12(11-7-17-19-13(11)5-8)18-14(21)20-24(22,23)10-3-1-2-9(16)6-10/h1-7H,(H,17,19)(H2,18,20,21) YEHXEPPMQOAFQQ-UHFFFAOYSA-N 50344565 CHEMBL1778443::N-(6-bromo-1H-indazol-4-ylcarbamoyl)-3-chlorobenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 3300 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344565&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 54584668 131347501 CHEMBL1778443 ZINC71340308 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641661 Cc1cccc(c1)S(=O)(=O)NC(=O)Nc1cc(Br)cc2[nH]ncc12 InChI=1S/C15H13BrN4O3S/c1-9-3-2-4-11(5-9)24(22,23)20-15(21)18-13-6-10(16)7-14-12(13)8-17-19-14/h2-8H,1H3,(H,17,19)(H2,18,20,21) KFHIDWMOWKGWLD-UHFFFAOYSA-N 50344566 CHEMBL1778444::N-(6-bromo-1H-indazol-4-ylcarbamoyl)-3-methylbenzenesulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 4500 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344566&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 54583700 131347502 CHEMBL1778444 ZINC71340941 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641662 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(Br)cc2[nH]ncc12 InChI=1S/C16H17BrN4O4S2/c1-9-5-15(26-14(9)3-4-25-2)27(23,24)21-16(22)19-12-6-10(17)7-13-11(12)8-18-20-13/h5-8H,3-4H2,1-2H3,(H,18,20)(H2,19,21,22) SOWKVXMEHQMTBS-UHFFFAOYSA-N 50344567 CHEMBL1778445::N-(6-bromo-1H-indazol-4-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 1700 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344567&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 54586599 131347503 CHEMBL1778445 ZINC71341088 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641663 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(Br)cc2nccn12 InChI=1S/C16H17BrN4O4S2/c1-10-7-15(26-12(10)3-6-25-2)27(23,24)20-16(22)19-14-9-11(17)8-13-18-4-5-21(13)14/h4-5,7-9H,3,6H2,1-2H3,(H2,19,20,22) UYTIUCIPEFRDAV-UHFFFAOYSA-N 50344568 CHEMBL1778446::N-(7-bromoimidazo[1,2-a]pyridin-5-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 8000 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344568&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 54581737 131347504 CHEMBL1778446 ZINC71333148 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641664 CNC(=O)Nc1cc(Br)cc(NC(=O)NS(=O)(=O)c2cc(C)c(CCOC)s2)n1 InChI=1S/C16H20BrN5O5S2/c1-9-6-14(28-11(9)4-5-27-3)29(25,26)22-16(24)21-13-8-10(17)7-12(19-13)20-15(23)18-2/h6-8H,4-5H2,1-3H3,(H4,18,19,20,21,22,23,24) OKYOPMCSUZGIPB-UHFFFAOYSA-N 50344569 CHEMBL1778447::N-(4-bromo-6-(3-methylureido)pyridin-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 1000 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344569&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 2C1 4MJO 42629276 131347505 CHEMBL1778447 ZINC71410826 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641665 CNC(=O)Nc1cc(SC)cc(NC(=O)NS(=O)(=O)c2cc(C)c(CCOC)s2)n1 InChI=1S/C17H23N5O5S3/c1-10-7-15(29-12(10)5-6-27-3)30(25,26)22-17(24)21-14-9-11(28-4)8-13(19-14)20-16(23)18-2/h7-9H,5-6H2,1-4H3,(H4,18,19,20,21,22,23,24) FMRLGOFZVHBMIH-UHFFFAOYSA-N 50344570 5-(2-methoxyethyl)-4-methyl-N-(4-(methylthio)-6-(3-methylureido)pyridin-2-ylcarbamoyl)thiophene-2-sulfonamide::CHEMBL1778448 Fructose-1,6-bisphosphatase 1 Mus musculus 1600 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344570&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42629397 131347506 CHEMBL1778448 ZINC71332511 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641666 CNC(=O)Nc1cc(OC)cc(NC(=O)NS(=O)(=O)c2cc(C)c(CCOC)s2)n1 InChI=1S/C17H23N5O6S2/c1-10-7-15(29-12(10)5-6-27-3)30(25,26)22-17(24)21-14-9-11(28-4)8-13(19-14)20-16(23)18-2/h7-9H,5-6H2,1-4H3,(H4,18,19,20,21,22,23,24) ISWOCAVPQAAWOZ-UHFFFAOYSA-N 50344571 1-[5-(2-METHOXYETHYL)-4-METHYL-THIOPHEN-2-YL]SULFONYL-3-[4-METHOXY-6-(METHYLCARBAMOYLAMINO)PYRIDIN-2-YL]UREA::CHEMBL1738935::N-(4-methoxy-6-(3-methylureido)pyridin-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 2600 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344571&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search YCU 2Y5K 51371083 131347507 CHEMBL1738935 ZINC66156879 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641667 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(Br)cc(N)n1 InChI=1S/C14H17BrN4O4S2/c1-8-5-13(24-10(8)3-4-23-2)25(21,22)19-14(20)18-12-7-9(15)6-11(16)17-12/h5-7H,3-4H2,1-2H3,(H4,16,17,18,19,20) MWPULXFKKSXXCB-UHFFFAOYSA-N 50344572 CHEMBL1778449::N-(6-amino-4-bromopyridin-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 1500 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344572&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42629393 131347508 CHEMBL1778449 ZINC71334795 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641668 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(Br)cc(NCC(F)(F)F)n1 InChI=1S/C16H18BrF3N4O4S2/c1-9-5-14(29-11(9)3-4-28-2)30(26,27)24-15(25)23-13-7-10(17)6-12(22-13)21-8-16(18,19)20/h5-7H,3-4,8H2,1-2H3,(H3,21,22,23,24,25) YBESQNWQFZXQMW-UHFFFAOYSA-N 50344573 CHEMBL1778450::N-(4-bromo-6-(2,2,2-trifluoroethylamino)pyridin-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 3700 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344573&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 54580733 131347509 CHEMBL1778450 ZINC71331313 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641669 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(SC)cc(N)n1 InChI=1S/C15H20N4O4S3/c1-9-6-14(25-11(9)4-5-23-2)26(21,22)19-15(20)18-13-8-10(24-3)7-12(16)17-13/h6-8H,4-5H2,1-3H3,(H4,16,17,18,19,20) HAFPBJXRPVPNLP-UHFFFAOYSA-N 50344574 CHEMBL1778451::N-(6-amino-4-(methylthio)pyridin-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 9000 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344574&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42629631 131347510 CHEMBL1778451 ZINC71341363 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641670 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(OC)cc(N)n1 InChI=1S/C15H20N4O5S2/c1-9-6-14(25-11(9)4-5-23-2)26(21,22)19-15(20)18-13-8-10(24-3)7-12(16)17-13/h6-8H,4-5H2,1-3H3,(H4,16,17,18,19,20) VENIPLAGGDDZTO-UHFFFAOYSA-N 50344575 CHEMBL1778452::N-(6-amino-4-methoxypyridin-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 30000 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344575&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42629630 131347511 CHEMBL1778452 ZINC71332625 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641671 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(cc(N)n1)C(F)(F)F InChI=1S/C15H17F3N4O4S2/c1-8-5-13(27-10(8)3-4-26-2)28(24,25)22-14(23)21-12-7-9(15(16,17)18)6-11(19)20-12/h5-7H,3-4H2,1-2H3,(H4,19,20,21,22,23) SRMKKUPSFXOFSN-UHFFFAOYSA-N 50344576 CHEMBL1778453::N-(6-amino-4-(trifluoromethyl)pyridin-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 6000 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344576&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42630486 131347512 CHEMBL1778453 ZINC71331470 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641672 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(c(F)c(N)n1)C(F)(F)F InChI=1S/C15H16F4N4O4S2/c1-7-5-11(28-9(7)3-4-27-2)29(25,26)23-14(24)22-10-6-8(15(17,18)19)12(16)13(20)21-10/h5-6H,3-4H2,1-2H3,(H4,20,21,22,23,24) AUTWHHYCTNKYNS-UHFFFAOYSA-N 50344577 CHEMBL1778454::N-(6-amino-5-fluoro-4-(trifluoromethyl)pyridin-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 3500 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344577&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42630357 131347513 CHEMBL1778454 ZINC71333103 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641673 Cc1cc(sc1CCO)S(=O)(=O)NC(=O)Nc1cc(c(F)c(N)n1)C(F)(F)F InChI=1S/C14H14F4N4O4S2/c1-6-4-10(27-8(6)2-3-23)28(25,26)22-13(24)21-9-5-7(14(16,17)18)11(15)12(19)20-9/h4-5,23H,2-3H2,1H3,(H4,19,20,21,22,24) ASGRHNNULIOUOW-UHFFFAOYSA-N 50344578 CHEMBL1778555::N-(6-amino-5-fluoro-4-(trifluoromethyl)pyridin-2-ylcarbamoyl)-5-(2-hydroxyethyl)-4-methylthiophene-2-sulfonamide Fructose-1,6-bisphosphatase 1 Mus musculus 4000 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344578&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42630485 131347514 CHEMBL1778555 ZINC71340506 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641674 CC(=O)OCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(c(F)c(N)n1)C(F)(F)F InChI=1S/C16H16F4N4O5S2/c1-7-5-12(30-10(7)3-4-29-8(2)25)31(27,28)24-15(26)23-11-6-9(16(18,19)20)13(17)14(21)22-11/h5-6H,3-4H2,1-2H3,(H4,21,22,23,24,26) GNTVDAGUYVYETP-UHFFFAOYSA-N 50344579 2-(5-(N-(6-amino-5-fluoro-4-(trifluoromethyl)pyridin-2-ylcarbamoyl)sulfamoyl)-3-methylthiophen-2-yl)ethyl acetate::CHEMBL1778556 Fructose-1,6-bisphosphatase 1 Mus musculus 3500 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344579&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42630482 131347515 CHEMBL1778556 ZINC71331824 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641675 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(cc(C)n1)C(F)(F)F InChI=1S/C16H18F3N3O4S2/c1-9-6-14(27-12(9)4-5-26-3)28(24,25)22-15(23)21-13-8-11(16(17,18)19)7-10(2)20-13/h6-8H,4-5H2,1-3H3,(H2,20,21,22,23) KYLSBKSUZYJHCQ-UHFFFAOYSA-N 50344580 5-(2-methoxyethyl)-4-methyl-N-(6-methyl-4-(trifluoromethyl)pyridin-2-ylcarbamoyl)thiophene-2-sulfonamide::CHEMBL1778557 Fructose-1,6-bisphosphatase 1 Mus musculus 7000 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344580&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 53235502 131347516 CHEMBL1778557 ZINC71335071 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641676 Cc1cc(sc1CCO)S(=O)(=O)NC(=O)Nc1cc(cc(C)n1)C(F)(F)F InChI=1S/C15H16F3N3O4S2/c1-8-5-13(26-11(8)3-4-22)27(24,25)21-14(23)20-12-7-10(15(16,17)18)6-9(2)19-12/h5-7,22H,3-4H2,1-2H3,(H2,19,20,21,23) XJLSAOYWVLDVOS-UHFFFAOYSA-N 50344581 5-(2-hydroxyethyl)-4-methyl-N-(6-methyl-4-(trifluoromethyl)pyridin-2-ylcarbamoyl)thiophene-2-sulfonamide::CHEMBL1778558 Fructose-1,6-bisphosphatase 1 Mus musculus 4000 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344581&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42628891 131347517 CHEMBL1778558 ZINC71334871 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641677 CC(=O)OCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(cc(C)n1)C(F)(F)F InChI=1S/C17H18F3N3O5S2/c1-9-6-15(29-13(9)4-5-28-11(3)24)30(26,27)23-16(25)22-14-8-12(17(18,19)20)7-10(2)21-14/h6-8H,4-5H2,1-3H3,(H2,21,22,23,25) RDPIGKWQPAYCNH-UHFFFAOYSA-N 50344582 2-(3-methyl-5-(N-(6-methyl-4-(trifluoromethyl)pyridin-2-ylcarbamoyl)sulfamoyl)thiophen-2-yl)ethyl acetate::CHEMBL1778559 Fructose-1,6-bisphosphatase 1 Mus musculus 7300 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344582&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42628889 131347518 CHEMBL1778559 ZINC71340849 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1 50641678 COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(ccn1)C(F)(F)F InChI=1S/C15H16F3N3O4S2/c1-9-7-13(26-11(9)4-6-25-2)27(23,24)21-14(22)20-12-8-10(3-5-19-12)15(16,17)18/h3,5,7-8H,4,6H2,1-2H3,(H2,19,20,21,22) PWFJIPFWCFTILU-UHFFFAOYSA-N 50344583 5-(2-methoxyethyl)-4-methyl-N-(4-(trifluoromethyl)pyridin-2-ylcarbamoyl)thiophene-2-sulfonamide::CHEMBL1778560 Fructose-1,6-bisphosphatase 1 Mus musculus 8300 ChEMBL 10.1016/j.bmcl.2011.04.044 10.7270/Q2C24WS9 21550236 Hebeisen, P; Haap, W; Kuhn, B; Mohr, P; Wessel, HP; Zutter, U; Kirchner, S; Ruf, A; Benz, J; Joseph, C; Alvarez-Sanchez, R; Gubler, M; Schott, B; Benardeau, A; Tozzo, E; Kitas, E F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003667&target=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344583&enzyme=Fructose-1%2C6-bisphosphatase+1&column=ki&startPg=0&Increment=50&submit=Search 42629632 131347519 CHEMBL1778560 ZINC71340670 1 MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK 1FBC,1FBD,1FBE,1FBF,1FBG,1FBH,1FBP,1FPB,1FPD,1FPE,1FPF,1FPG,1FPI,1FPJ,1FPK,1FPL,2FBP,3FBP,4FBP,4GBV,4GBW,5FBP Fructose-1,6-bisphosphatase 1 F16P1_MOUSE Q9QXD6 P97323 Q3UEH1