Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ic50 for UniProtKB: P03366
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM2058(2,8-disubstituted dipyridodiazepinone 41 | 2-Chlor...)
Affinity DataIC50:  26nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10230(5-chloro-13-{[(2,6-dimethylpyridin-4-yl)sulfanyl]m...)
Affinity DataIC50:  60nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10227(5-chloro-2-ethyl-7-methyl-13-[(pyridin-4-ylsulfany...)
Affinity DataIC50:  80nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10234(13-{[(2,6-dimethylpyridin-4-yl)sulfanyl]methyl}-2-...)
Affinity DataIC50:  120nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10235(13-{[(2,6-dimethylpyridin-4-yl)sulfanyl]methyl}-2-...)
Affinity DataIC50:  170nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10233(13-[(1,3-benzoxazol-2-ylsulfanyl)methyl]-5-chloro-...)
Affinity DataIC50:  230nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10236(5-chloro-2-cyclopropyl-13-{[(2,6-dimethylpyridin-4...)
Affinity DataIC50:  280nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10228(5-chloro-2-ethyl-7-methyl-13-{[(2-methylpyridin-4-...)
Affinity DataIC50:  310nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10232(5-chloro-13-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl...)
Affinity DataIC50:  320nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10229(5-chloro-2-ethyl-7-methyl-13-{[(3-methylpyridin-4-...)
Affinity DataIC50:  1.64E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1027,K702N,Y780C]/[600-1155,K702N,Y780C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM10231(5-chloro-2-ethyl-7-methyl-13-[(pyrimidin-5-ylsulfa...)
Affinity DataIC50:  5.00E+3nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed