Compile Data Set for Download or QSAR
Report error Found 5 of ki for UniProtKB: P00519
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of California San Francisco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13530BDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataKi:  14nMAssay Description:Inhibition of Bcr-AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of California San Francisco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13216BDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataKi:  30nMAssay Description:Binding affinity to Bcr-Abl (unknown origin) assessed as inhibition constant in presence of ATP by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of California San Francisco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004205BDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataKi:  30nMAssay Description:Binding affinity to wild type BCR-ABL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of California San Francisco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31089BDBM31089(DASATINIB | US20250340886, Compound A8)
Affinity DataKi:  30nMAssay Description:Binding affinity to wild type human BCR-ABL1 using Tyr2 peptide as substrate assessed as inhibition constant Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
University of California San Francisco

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004205BDBM50004205(MK-0457 | MK-045 | VX-680 | VX-68 | TOZASERTIB | U...)
Affinity DataKi:  42nMAssay Description:Binding affinity to wild type BCR-ABL T315I mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed