Compile Data Set for Download or QSAR
Report error Found 41 of ic50 for UniProtKB: P32297
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170589BDBM50170589((3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481206BDBM50481206(CHEMBL595311)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170586BDBM50170586((3S)-3-{[(2S)-1-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2...)
Affinity DataIC50: 0.75nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2; Range is 0.3-1.5 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50445323BDBM50445323(CHEMBL3104236)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481212BDBM50481212(CHEMBL609593)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140089BDBM50140089(GCCSHPACAGNNQHIC* | CHEMBL437423)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170592BDBM50170592(CHEMBL411146)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2; Range is 0.3-1.5 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081733BDBM50081733(3-[1-(3-Methyl-isoxazol-5-yl)-meth-(Z)-ylidene]-1-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481211BDBM50481211(CHEMBL595312)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82070BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataIC50: 3.80nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170584BDBM50170584(CHEMBL411145)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2; Range is 3-5 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481207BDBM50481207(CHEMBL595286)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140087BDBM50140087(GCCSNPVCHLEHSNLC* | CHEMBL265198)
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2; Range is 0.5-8 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481208BDBM50481208(CHEMBL594330)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170600BDBM50170600((3S)-3-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(...)
Affinity DataIC50: 9.60nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481210BDBM50481210(CHEMBL609594)
Affinity DataIC50: 11nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083075BDBM50083075(3-(3-Methyl-isoxazol-5-ylmethylene)-1-aza-bicyclo[...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083057BDBM50083057(3-[1-(3-Methyl-isoxazol-5-yl)-meth-(Z)-ylidene]-1-...)
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line Sf 9 by using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601896BDBM50601896(CHEMBL5203781)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170588BDBM50170588(CHEMBL451252)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50445327BDBM50445327(CHEMBL3104240)
Affinity DataIC50: 33nMAssay Description:Inhibition of alpha3beta2 nAChR (unknown origin) expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50445329BDBM50445329(CHEMBL3104242)
Affinity DataIC50: 41nMAssay Description:Inhibition of human alpha3beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170603BDBM50170603((3S)-3-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(...)
Affinity DataIC50: 61nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035398BDBM50035398(ABT-418 | (S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-...)
Affinity DataIC50: 62nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481209BDBM50481209(CHEMBL595047)
Affinity DataIC50: 74nMAssay Description:Inhibition of alpha3beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50445325BDBM50445325(CHEMBL3104238)
Affinity DataIC50: 74nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083076BDBM50083076(6-(3-Methyl-isoxazol-5-ylmethylene)-1-aza-bicyclo[...)
Affinity DataIC50: 117nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083069BDBM50083069(6-[1-(3-Methyl-isoxazol-5-yl)-meth-(Z)-ylidene]-1-...)
Affinity DataIC50: 217nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601894BDBM50601894(CHEMBL5196098)
Affinity DataIC50: 219nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170594BDBM50170594((16R)-9,33-dihydroxy-10,25-dimethoxy-15,15,30-trim...)
Affinity DataIC50: 230nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50369323BDBM50369323(MECAMYLAMINE)
Affinity DataIC50: 280nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083079BDBM50083079(3-[1-(3-Methyl-isoxazol-5-yl)-meth-(E)-ylidene]-1-...)
Affinity DataIC50: 854nMAssay Description:Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048392BDBM50048392(BUPROPION HYDROCHLORIDE | CHEMBL894 | 2-(tert-buty...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061562BDBM50061562(CHEMBL335712 | Dihydro-Beta-erythroidine | (12R,13...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170594BDBM50170594((16R)-9,33-dihydroxy-10,25-dimethoxy-15,15,30-trim...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2 expressed in xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581246BDBM50581246(CHEMBL5080428)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606633BDBM50606633(CHEMBL5219936)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581248BDBM50581248(CHEMBL5090753)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50567433BDBM50567433(CHEMBL4869892)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50567435BDBM50567435(CHEMBL4872191)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061562BDBM50061562(CHEMBL335712 | Dihydro-Beta-erythroidine | (12R,13...)
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha3-beta2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed