Compile Data Set for Download or QSAR
Report error Found 177 of ic50 for UniProtKB: Q2FYS5
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50494811BDBM50494811(CHEMBL3094350)
Affinity DataIC50: 15.5nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit ParC2/ParE2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50494806BDBM50494806(CHEMBL3094349)
Affinity DataIC50: 23.8nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit ParC2/ParE2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572198BDBM50572198(CHEMBL4873479)
Affinity DataIC50: 50nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572196BDBM50572196(CHEMBL4879265)
Affinity DataIC50: 90nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440321BDBM50440321(CHEMBL2424893)
Affinity DataIC50: 125nMAssay Description:Inhibition of wild type Staphylococcus aureus ATCC 29213 topoisomerase-4 subunit 2GrlA/2GrlB assessed as pBR322 relaxation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561963BDBM50561963(CHEMBL4787821)
Affinity DataIC50: 190nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase-4 assessed as reduction in decatenation of kinetoplast DNA agarose gel electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572197BDBM50572197(CHEMBL4879088)
Affinity DataIC50: 215nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582949BDBM50582949(CHEMBL5090088)
Affinity DataIC50: 230nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using kDNA as substrate incubated for 30 mins by fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572195BDBM50572195(CHEMBL4868908)
Affinity DataIC50: 241nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547867BDBM50547867(CHEMBL4793192)
Affinity DataIC50: 290nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547859BDBM50547859(CHEMBL4752708)
Affinity DataIC50: 290nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561965BDBM50561965(CHEMBL4787145)
Affinity DataIC50: 300nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase-4 assessed as reduction in decatenation of kinetoplast DNA agarose gel electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393503BDBM50393503(CHEMBL2158050)
Affinity DataIC50: 300nMAssay Description:Inhibition of Staphylococcus aureus RN4220 DNA topoisomerase 4 expressed in Escherichia coli BL21(DE3) cells using supercoiled pBR322 DNA as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577588BDBM50577588(CHEMBL4875924)
Affinity DataIC50: 310nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577587BDBM50577587(CHEMBL4869929)
Affinity DataIC50: 320nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582944BDBM50582944(CHEMBL5086095)
Affinity DataIC50: 350nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using kDNA as substrate incubated for 30 mins by fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577579BDBM50577579(CHEMBL4867964)
Affinity DataIC50: 380nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582952BDBM50582952(CHEMBL5087299)
Affinity DataIC50: 390nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using kDNA as substrate incubated for 30 mins by fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597278BDBM50597278(CHEMBL5196889)
Affinity DataIC50: 420nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577585BDBM50577585(CHEMBL4856026)
Affinity DataIC50: 430nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582950BDBM50582950(CHEMBL5075535)
Affinity DataIC50: 440nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using kDNA as substrate incubated for 30 mins by fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440312BDBM50440312(CHEMBL2424891)
Affinity DataIC50: 500nMAssay Description:Inhibition of wild type Staphylococcus aureus ATCC 29213 topoisomerase-4 subunit 2GrlA/2GrlB assessed as pBR322 relaxation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440323BDBM50440323(CHEMBL2424833)
Affinity DataIC50: 500nMAssay Description:Inhibition of wild type Staphylococcus aureus ATCC 29213 topoisomerase-4 subunit 2GrlA/2GrlB assessed as pBR322 relaxation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440327BDBM50440327(CHEMBL2424883)
Affinity DataIC50: 500nMAssay Description:Inhibition of wild type Staphylococcus aureus ATCC 29213 topoisomerase-4 subunit 2GrlA/2GrlB assessed as pBR322 relaxation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440332BDBM50440332(CHEMBL2424885)
Affinity DataIC50: 500nMAssay Description:Inhibition of wild type Staphylococcus aureus ATCC 29213 topoisomerase-4 subunit 2GrlA/2GrlB assessed as pBR322 relaxation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440325BDBM50440325(CHEMBL2424890)
Affinity DataIC50: 500nMAssay Description:Inhibition of wild type Staphylococcus aureus ATCC 29213 topoisomerase-4 subunit 2GrlA/2GrlB assessed as pBR322 relaxation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597266BDBM50597266(CHEMBL5200272)
Affinity DataIC50: 540nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 550nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using kDNA as substrate incubated for 30 mins by fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597267BDBM50597267(CHEMBL5201666)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050549BDBM50050549(GSK2140944 | Gepotidacin)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577565BDBM50577565(CHEMBL4850745)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582946BDBM50582946(CHEMBL5092701)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using kDNA as substrate incubated for 30 mins by fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582940BDBM50582940(CHEMBL5084320)
Affinity DataIC50: 640nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using kDNA as substrate incubated for 30 mins by fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249796BDBM50249796(CHEMBL4752072)
Affinity DataIC50: 690nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using biotinylated oligonucleotide as substrate incubated for 30 mins in presence of ATP by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561966BDBM50561966(CHEMBL4759626)
Affinity DataIC50: 700nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase-4 assessed as reduction in decatenation of kinetoplast DNA agarose gel electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572201BDBM50572201(CHEMBL4864750)
Affinity DataIC50: 725nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249794BDBM50249794(CHEMBL4785583)
Affinity DataIC50: 830nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using biotinylated oligonucleotide as substrate incubated for 30 mins in presence of ATP by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577575BDBM50577575(CHEMBL4851183)
Affinity DataIC50: 870nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561964BDBM50561964(CHEMBL4755744)
Affinity DataIC50: 890nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase-4 assessed as reduction in decatenation of kinetoplast DNA agarose gel electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547857BDBM50547857(CHEMBL4792173)
Affinity DataIC50: 910nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249798BDBM50249798(CHEMBL4795890)
Affinity DataIC50: 960nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using biotinylated oligonucleotide as substrate incubated for 30 mins in presence of ATP by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577577BDBM50577577(CHEMBL4848487)
Affinity DataIC50: 990nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572194BDBM50572194(CHEMBL4862136)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597276BDBM50597276(CHEMBL5177294)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577589BDBM50577589(CHEMBL4869986)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582953BDBM50582953(CHEMBL5087899)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using kDNA as substrate incubated for 30 mins by fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572200BDBM50572200(CHEMBL4862951)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577580BDBM50577580(CHEMBL4865826)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577581BDBM50577581(CHEMBL4874489)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597275BDBM50597275(CHEMBL5197372)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
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