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TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataIC50: 6.10nMAssay Description:Concentration required for inhibition of 5-hydroxytryptamine 2 receptor using [3H]ketanserin as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005836(4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-...)
Affinity DataIC50: 6.10nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM82368(NSC_121851 | CAS_121851 | CHEMBL301060 | CHEMBL115...)
Affinity DataIC50: 10nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details

TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50212607(CHEMBL57330)
Affinity DataIC50: 15nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details

TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for its affinity towards 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403897(CHEMBL334923)
Affinity DataIC50: 3.16E+3nMAssay Description:Compound was tested for binding affinity against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155152(4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-yl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required for inhibition of 5-hydroxytryptamine 2 receptor using [3H]ketanserin as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details

TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50033447(CHEMBL321818 | CHEMBL120055 | 2-[3-(2-Amino-ethyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its affinity towards 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for inhibitory activity against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50284689(CP-96486 | 7-Chloro-2-((E)-2-{3-[4-(2-methyl-imida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181836(CHEMBL319673 | 4-amino-N-1-azatricyclo[3.3.1.0~3,7...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181840((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005833(4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181839(N-exo-((4S,7alphaS)-tetrahydro-1H-pyrrolizin-4(5H)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181837((1S,7aR)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-meth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181841((1S,7aR)-hexahydro-1H-pyrrolizin-1-ylmethyl 1H-ind...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155153(4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-ylmet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required for inhibition of 5-hydroxytryptamine 2 receptor using [3H]ketanserin as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181836(CHEMBL319673 | 4-amino-N-1-azatricyclo[3.3.1.0~3,7...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required for inhibition of 5-hydroxytryptamine 2 receptor using [3H]ketanserin as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50212622(CHEMBL57187)
Affinity DataIC50: 1.80E+4nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details

TargetSerotonin 2 (5-HT2) receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details