Compile Data Set for Download or QSAR
Report error Found 152 of ic50 for UniProtKB: P23219
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50229761(L-689037 | CHEMBL314337)
Affinity DataIC50: 2nMAssay Description:The compound was tested for inhibitory activity against Prostaglandin G/H synthase in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012780(Prifelone | CHEMBL8846 | (3,5-Di-tert-butyl-4-hydr...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against cyclooxygenase of human platelets was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279050(CHEMBL4169347)
Affinity DataIC50: 23nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50: 27nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279039(CHEMBL4177185)
Affinity DataIC50: 28nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50076659(N-{3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279036(CHEMBL4162061)
Affinity DataIC50: 33nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012811(CHEMBL266100 | 2,6-Di-tert-butyl-4-(2-thiophen-2-y...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279034(CHEMBL4172740)
Affinity DataIC50: 34nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279035(CHEMBL4165597)
Affinity DataIC50: 38nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279023(CHEMBL4176892)
Affinity DataIC50: 41nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279038(CHEMBL4169030)
Affinity DataIC50: 44nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50279040(CHEMBL4161755)
Affinity DataIC50: 50nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 89nMAssay Description:Inhibition of human kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50471018(CHEMBL47644)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50008950(3-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(E)...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000399(CHEMBL292136)
Affinity DataIC50: 110nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000360(CHEMBL55680)
Affinity DataIC50: 190nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000390(CHEMBL58990)
Affinity DataIC50: 230nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012789(CHEMBL414824 | 2,6-Di-tert-butyl-4-(2-pyridin-3-yl...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012794(CHEMBL56563 | 4-[2-(4-Fluoro-phenyl)-ethyl]-2,6-di...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50044080(CHEMBL196996 | 2-Amino-5-[1-(3,5-di-tert-butyl-4-h...)
Affinity DataIC50: 390nMAssay Description:Inhibitory concentration against prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000370(CHEMBL55448)
Affinity DataIC50: 400nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012780(Prifelone | CHEMBL8846 | (3,5-Di-tert-butyl-4-hydr...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012802(CHEMBL56551 | 4-[2-(4-Ethyl-phenyl)-vinyl]-2,6-dim...)
Affinity DataIC50: 510nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000396(CHEMBL55737)
Affinity DataIC50: 590nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012809(CHEMBL8813 | 2,6-Di-tert-butyl-4-[2-(4-fluoro-phen...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012770(CHEMBL56009 | 4-[2-(4-Fluoro-phenyl)-propenyl]-2,6...)
Affinity DataIC50: 630nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012789(CHEMBL414824 | 2,6-Di-tert-butyl-4-(2-pyridin-3-yl...)
Affinity DataIC50: 670nMAssay Description:Inhibitory concentration required for inhibition of Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2019
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000397(CHEMBL58987)
Affinity DataIC50: 710nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012783(CHEMBL56833 | 2-Allyl-6-methyl-4-(2-thiophen-2-yl-...)
Affinity DataIC50: 730nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012786(CHEMBL417379 | 4-[2-(4-Chloro-phenyl)-vinyl]-2,6-d...)
Affinity DataIC50: 750nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000386(CHEMBL440480)
Affinity DataIC50: 780nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012778(CHEMBL56798 | 2,6-Dimethyl-4-(2-thiophen-2-yl-viny...)
Affinity DataIC50: 780nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012796(CHEMBL55389 | (4-Hydroxy-3,5-dimethyl-phenyl)-thio...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000392(CHEMBL56422)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000364(CHEMBL56460)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000395(CHEMBL57016)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000371(CHEMBL301304)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000394(CHEMBL8595)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000381(CHEMBL293150)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000393(CHEMBL299048)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012785(CHEMBL300159 | 4-[2-(2-Methoxy-phenyl)-vinyl]-2,6-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50000354(CHEMBL293755)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012790(CHEMBL56576 | 4-[2-(2,5-Dimethyl-phenyl)-vinyl]-2,...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012806(CHEMBL57358 | 4-[2-(4-Fluoro-phenyl)-vinyl]-2,6-di...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012779(CHEMBL434783 | 2-Methoxy-6-propyl-4-(2-thiophen-2-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012804(CHEMBL55293 | 4-[2-(4-Isopropyl-phenyl)-vinyl]-2,6...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50012773(CHEMBL293825 | 2-Ethyl-6-methoxy-4-(2-thiophen-2-y...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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