Compile Data Set for Download or QSAR
Report error Found 16 of ki for UniProtKB: P09483
LigandPNGBDBM50143320(2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]hept...)
Affinity DataKi:  0.0180nM ΔG°:  -14.6kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221044(US9284322, Table 6, Compound 10)
Affinity DataKi:  0.0400nM ΔG°:  -14.2kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221036(US9284322, Table 6, Compound 2)
Affinity DataKi:  0.0490nM ΔG°:  -14.1kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221037(US9284322, Table 6, Compound 3)
Affinity DataKi:  0.0630nM ΔG°:  -13.9kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221041(US9284322, Table 6, Compound 7)
Affinity DataKi:  0.0670nM ΔG°:  -13.9kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221045(US9284322, Table 7, Compound 1)
Affinity DataKi:  0.120nM ΔG°:  -13.5kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221040(US9284322, Table 6, Compound 6)
Affinity DataKi:  0.120nM ΔG°:  -13.5kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221048(US9303017, Varenicline | US9284322, varenicline)
Affinity DataKi:  0.120nM ΔG°:  -13.5kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM221043(US9284322, Table 6, Compound 9)
Affinity DataKi:  0.130nM ΔG°:  -13.5kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221039(US9284322, Table 6, Compound 5)
Affinity DataKi:  0.130nM ΔG°:  -13.5kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221038(US9284322, Table 6, Compound 4)
Affinity DataKi:  0.25nM ΔG°:  -13.1kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221049(US9284322, Table 7, Compound 3)
Affinity DataKi:  0.320nM ΔG°:  -12.9kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221035(US9284322, Table 6, Compound 1)
Affinity DataKi:  0.350nM ΔG°:  -12.9kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221046(US9284322, Table 7, Compound 2)
Affinity DataKi:  0.840nM ΔG°:  -12.4kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM221042(US9284322, Table 6, Compound 8)
Affinity DataKi:  1.18nM ΔG°:  -12.2kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent

LigandPNGBDBM50004108((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...)
Affinity DataKi:  1.5nM ΔG°:  -12.0kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2017
Entry Details
US Patent