Compile Data Set for Download or QSAR
Report error Found 8 of ki for UniProtKB: P03367
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Florida College of Medicine

LigandPNGBDBM580(AG1776 | (4R)-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2...)
Affinity DataKi:  0.0210nM ΔG°:  -15.1kcal/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Florida College of Medicine

LigandPNGBDBM17350(CHEMBL386563 | (4S)-4-[(2S)-2-{[(2S,3S)-3-{[(tert-...)
Affinity DataKi:  0.150nMpH: 4.7Assay Description:Inhibition constants were determined by a spectrophotometric assay with the chromogenic peptide substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2004
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Florida College of Medicine

LigandPNGBDBM579(Kynostatin 272 | CHEMBL414640 | (4R)-N-tert-butyl-...)
Affinity DataKi:  0.580nM ΔG°:  -13.1kcal/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Florida College of Medicine

LigandPNGBDBM520(ABT-538 | Norvir | CHEMBL163 | 1,3-thiazol-5-ylmet...)
Affinity DataKi:  0.700nM ΔG°:  -13.0kcal/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Florida College of Medicine

LigandPNGBDBM518(Viracept | CHEMBL584 | (3S,4aS,8aS)-N-tert-butyl-2...)
Affinity DataKi:  1.20nM ΔG°:  -12.7kcal/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Florida College of Medicine

LigandPNGBDBM17351(CHEMBL215431 | (4S)-4-[(2S)-2-{[(3S)-3-{[(tert-but...)
Affinity DataKi:  1.5nMpH: 4.7Assay Description:Inhibition constants were determined by a spectrophotometric assay with the chromogenic peptide substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Florida College of Medicine

LigandPNGBDBM517(Crixivan | CHEMBL115 | L-735, 524 | MK639 | Indina...)
Affinity DataKi:  3.10nM ΔG°:  -12.1kcal/molepH: 4.7 T: 2°CAssay Description:The inhibition constant, Ki was determined by monitoring the competitive inhibition of the hydrolysis of the chromogenic substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University of Florida College of Medicine

LigandPNGBDBM17349(CHEMBL386758 | tert-butyl N-[(2S,3S)-4-{[(1S)-1-{[...)
Affinity DataKi:  33nMpH: 4.7Assay Description:Inhibition constants were determined by a spectrophotometric assay with the chromogenic peptide substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2004
Entry Details Article
PubMed