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TargetIsoform C of Beta-secretase 1 (BACE-I-457)(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM113392(US8633212, 578 | US9212153, 578 | US10336717, Comp...)
Affinity DataIC50: 3.90nMAssay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
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TargetBeta-secretase 1 [1-458](Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM113392(US8633212, 578 | US9212153, 578 | US10336717, Comp...)
Affinity DataIC50: 3.90nMpH: 4.4Assay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM113392(US8633212, 578 | US9212153, 578 | US10336717, Comp...)
Affinity DataIC50: 3.90nMAssay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
Go to US Patent