Compile Data Set for Download or QSAR
Report error Found 2 of ic50 for monomerid = 17786
TargetCathepsin D(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 17786BDBM17786((4S)-4-(2-amino-6-phenoxy-3,4-dihydroquinazolin-3-...)
Affinity DataIC50: 110nMpH: 4.0 T: 2°CAssay Description:Cathepsin D activity was measured at pH 4 using a FRET peptide substrate. Compounds were preincubated with recombinant human liver cathepsin D for 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2007
Entry Details Article
PubMed
TargetRenin(Human)
Johnson & Johnson Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 17786BDBM17786((4S)-4-(2-amino-6-phenoxy-3,4-dihydroquinazolin-3-...)
Affinity DataIC50: 2.70E+3nMpH: 7.4 T: 2°CAssay Description:Renin activity was measured at pH 7.4 using a FRET peptide substrate. Compounds were added to recombinant human rennin and mixed before substrate was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2007
Entry Details Article
PubMed