Compile Data Set for Download or QSAR
Report error Found 5 of ic50 for monomerid = 23447
LigandChemical structure of BindingDB Monomer ID 23447BDBM23447(Chloromycetin | 2,2-dichloro-N-[(1R,2R)-1,3-dihydr...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 23447BDBM23447(Chloromycetin | 2,2-dichloro-N-[(1R,2R)-1,3-dihydr...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23447BDBM23447(Chloromycetin | 2,2-dichloro-N-[(1R,2R)-1,3-dihydr...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23447BDBM23447(Chloromycetin | 2,2-dichloro-N-[(1R,2R)-1,3-dihydr...)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23447BDBM23447(Chloromycetin | 2,2-dichloro-N-[(1R,2R)-1,3-dihydr...)
Affinity DataIC50: 9.58E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed