Compile Data Set for Download or QSAR
Report error Found 7 of ic50 for monomerid = 31777
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Universidad de Buenos Aires

Curated by ChEMBL
LigandPNGBDBM31777(thieno[2,3-d]pyrimidine deriv., 2)
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Universidad de Buenos Aires

Curated by ChEMBL
LigandPNGBDBM31777(thieno[2,3-d]pyrimidine deriv., 2)
Affinity DataIC50: 2.10nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
Duquesne University

LigandPNGBDBM31777(thieno[2,3-d]pyrimidine deriv., 2)
Affinity DataIC50: 18nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM31777(thieno[2,3-d]pyrimidine deriv., 2)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

LigandPNGBDBM31777(thieno[2,3-d]pyrimidine deriv., 2)
Affinity DataIC50: 54nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Universidad de Buenos Aires

Curated by ChEMBL
LigandPNGBDBM31777(thieno[2,3-d]pyrimidine deriv., 2)
Affinity DataIC50: 90nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Duquesne University

LigandPNGBDBM31777(thieno[2,3-d]pyrimidine deriv., 2)
Affinity DataIC50: 1.00E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed