Compile Data Set for Download or QSAR
Report error Found 7 of ic50 for monomerid = 31787
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Universidad de Buenos Aires

Curated by ChEMBL
LigandPNGBDBM31787(thieno[2,3-d]pyrimidine deriv., 2j)
Affinity DataIC50: 10nMAssay Description:Inhibition of Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Universidad de Buenos Aires

Curated by ChEMBL
LigandPNGBDBM31787(thieno[2,3-d]pyrimidine deriv., 2j)
Affinity DataIC50: 13nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM31787(thieno[2,3-d]pyrimidine deriv., 2j)
Affinity DataIC50: 260nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

LigandPNGBDBM31787(thieno[2,3-d]pyrimidine deriv., 2j)
Affinity DataIC50: 390nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Universidad de Buenos Aires

Curated by ChEMBL
LigandPNGBDBM31787(thieno[2,3-d]pyrimidine deriv., 2j)
Affinity DataIC50: 2.20E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli (strain K12))
Duquesne University

LigandPNGBDBM31787(thieno[2,3-d]pyrimidine deriv., 2j)
Affinity DataIC50: 2.20E+3nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Duquesne University

LigandPNGBDBM31787(thieno[2,3-d]pyrimidine deriv., 2j)
Affinity DataIC50: 2.90E+4nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed