Compile Data Set for Download or QSAR
Report error Found 6 of ic50 for monomerid = 370488
TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 370488BDBM370488(1-(4,4-difluorocyclohexyl)-2-(6-fluoro-5H- imidazo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 370488BDBM370488(1-(4,4-difluorocyclohexyl)-2-(6-fluoro-5H- imidazo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Newlink Genetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 370488BDBM370488(1-(4,4-difluorocyclohexyl)-2-(6-fluoro-5H- imidazo...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Newlink Genetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 370488BDBM370488(1-(4,4-difluorocyclohexyl)-2-(6-fluoro-5H- imidazo...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Newlink Genetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 370488BDBM370488(1-(4,4-difluorocyclohexyl)-2-(6-fluoro-5H- imidazo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Newlink Genetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 370488BDBM370488(1-(4,4-difluorocyclohexyl)-2-(6-fluoro-5H- imidazo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed