Compile Data Set for Download or QSAR
Report error Found 4 of ic50 for monomerid = 50131428
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131428(CHEMBL32 | 1-Cyclopropyl-6-fluoro-8-methoxy-7-(oct...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against wild type Escherichia coli gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131428(CHEMBL32 | 1-Cyclopropyl-6-fluoro-8-methoxy-7-(oct...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against wild type Staphylococcus aureus topoisomerase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131428(CHEMBL32 | 1-Cyclopropyl-6-fluoro-8-methoxy-7-(oct...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against Staphylococcus aureus ATCC 29213 wild type Topo 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA gyrase subunit A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Achillion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50131428(CHEMBL32 | 1-Cyclopropyl-6-fluoro-8-methoxy-7-(oct...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of DNA supercoiling activity of wild type Mycobacterium tuberculosis DNA gyrase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed