Compile Data Set for Download or QSAR
Report error Found 9 of ic50 for monomerid = 50226465
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226465BDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 2.40nMAssay Description:Inhibitory concentration against Pregnane X receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226465BDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226465BDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against Mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
University of Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226465BDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory concentration against Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226465BDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibitory concentration against Glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226465BDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226465BDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 4.10E+4nMAssay Description:Antagonist activity at human FXR expressed in HEK293 cells assessed as inhibition of GW4064-induced transactivation after 24 hrs by luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226465BDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 4.40E+4nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226465BDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Farnesoid X receptor; range from 50-100000More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed