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Report error Found 6 of ic50 for monomerid = 50359061
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359061BDBM50359061(CHEMBL1922532)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359061BDBM50359061(CHEMBL1922532)
Affinity DataIC50: 1.70nMAssay Description:Displacement of [3H]-3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzylindol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359061BDBM50359061(CHEMBL1922532)
Affinity DataIC50: 87nMAssay Description:Inhibition of FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359061BDBM50359061(CHEMBL1922532)
Affinity DataIC50: 328nMAssay Description:Inhibition of FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 15 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359061BDBM50359061(CHEMBL1922532)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of COX1-mediated TXB2 production in human whole blood after 15 mins by competitive enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359061BDBM50359061(CHEMBL1922532)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of COX1-mediated TXB2 production in human whole blood after 5 hrs by competitive enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed