Compile Data Set for Download or QSAR
Report error Found 5 of ic50 for monomerid = 50466622
TargetRetinal dehydrogenase 2(Chicken)
University of Oklahoma Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50466622(CHEMBL4286209)
Affinity DataIC50: 54nMAssay Description:Inhibition of RALDH2 in choroidal cytosol fraction from 4 day recovering chick assessed as inhibition of ATRA synthesis pre-incubated for 20 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Chicken)
University of Oklahoma Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50466622(CHEMBL4286209)
Affinity DataIC50: 55nMAssay Description:Inhibition of N-terminal His6-tagged recombinant chick RALDH2 expressed in Escherichia coli BL21(DE3) cells using RAL as substrate preincubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Chicken)
University of Oklahoma Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50466622(CHEMBL4286209)
Affinity DataIC50: 187nMAssay Description:Inhibition of chick RALDH2 expressed in doxycycline-inducible HEK293 cells assessed as inhibition of ATRA synthesis after 24 hrs in presence of ATRA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRetinal dehydrogenase 2(Human)
University of Oklahoma Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50466622(CHEMBL4286209)
Affinity DataIC50: 191nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human RALDH2 using RAL as substrate preincubated for 20 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAldehyde dehydrogenase 1A1(Chicken)
University of Oklahoma Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50466622(CHEMBL4286209)
Affinity DataIC50: 435nMAssay Description:Inhibition of N-terminal His6-tagged recombinant chick RALDH1 expressed in Escherichia coli BL21(DE3) cells using RAL as substrate preincubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed