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TargetCyclin-dependent kinase 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525732(US11174252, Compound 27)
Affinity DataIC50:  1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCyclin-dependent kinase 6(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525732(US11174252, Compound 27)
Affinity DataIC50:  5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMacrophage colony-stimulating factor 1 receptor(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525732(US11174252, Compound 27)
Affinity DataIC50:  7.5nMAssay Description:FMS: IC50 values of compounds against FMS kinase were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen (Life Technologies Grand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent