Compile Data Set for Download or QSAR
Report error Found 4 of ki for monomerid = 205423
TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM205423(US9243020, 17 | US9815861, Example 17)
Affinity DataKi:  0.5nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM205423(US9243020, 17 | US9815861, Example 17)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM205423(US9243020, 17 | US9815861, Example 17)
Affinity DataKi:  0.550nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetBeta-hexosaminidase subunit beta(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM205423(US9243020, 17 | US9815861, Example 17)
Affinity DataKi:  790nMAssay Description:Inhibition of human beta hexosaminidase assessed as inhibitory constant using 4-methylumbelliferyl N-acetyl-beta-D-glucosaminide dihydrate as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed