Compile Data Set for Download or QSAR
Report error Found 2 of ki for monomerid = 25367
TargetGag-Pol polyprotein(HIV-1)
Purdue Research Foundation

US Patent
LigandPNGBDBM25367((5R)-1,3-dioxepan-5-yl N-[(2S,3R)-3-hydroxy-4-[(4-...)
Affinity DataKi:  0.0260nMAssay Description:Enzyme inhibitory assay utilizes a protocol described by Toth and Marshall (Toth, M. V.; Marshall G.R. A simple, continuous fluormetric assay for HIV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM25367((5R)-1,3-dioxepan-5-yl N-[(2S,3R)-3-hydroxy-4-[(4-...)
Affinity DataKi:  0.0260nM ΔG°:  -60.4kJ/mole IC50: 4.90nMpH: 6.4 T: 2°CAssay Description:The Ki values were determined by substrate cleavage assay using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2. A standar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed