Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ki for monomerid = 35648
TargetAurora kinase A(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM35648(pyrimidylpyrrole, 10a)
Affinity DataKi:  270nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM35648(pyrimidylpyrrole, 10a)
Affinity DataKi:  540nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM35648(pyrimidylpyrrole, 10a)
Affinity DataKi:  670nM ΔG°:  -35.8kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM35648(pyrimidylpyrrole, 10a)
Affinity DataKi:  1.10E+3nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed