Compile Data Set for Download or QSAR
Report error Found 8 of ki for monomerid = 50092324
TargetBromodomain-containing protein 3 [326-398](Human)
University of Michigan

US Patent
LigandPNGBDBM50092324(US9675697, Cpd. No. 1 | CHEMBL3581655)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandPNGBDBM50092324(US9675697, Cpd. No. 1 | CHEMBL3581655)
Affinity DataKi:  15nM ΔG°:  -44.7kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 2 [91-163](Human)
University of Michigan

US Patent
LigandPNGBDBM50092324(US9675697, Cpd. No. 1 | CHEMBL3581655)
Affinity DataKi:  32nM ΔG°:  -42.8kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
University of Michigan

US Patent
LigandPNGBDBM50092324(US9675697, Cpd. No. 1 | CHEMBL3581655)
Affinity DataKi:  35nM ΔG°:  -42.6kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50092324(US9675697, Cpd. No. 1 | CHEMBL3581655)
Affinity DataKi:  48nMAssay Description:Displacement of FAM-labeled ZBA248 from BRD4 BD1 (44 to 168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [75-147](Human)
University of Michigan

US Patent
LigandPNGBDBM50092324(US9675697, Cpd. No. 1 | CHEMBL3581655)
Affinity DataKi:  48nM ΔG°:  -41.8kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50092324(US9675697, Cpd. No. 1 | CHEMBL3581655)
Affinity DataKi:  70nMAssay Description:Displacement of FAM-labeled ZBA248 from BRD4 BD2 (333 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 2 [364-436](Human)
University of Michigan

US Patent
LigandPNGBDBM50092324(US9675697, Cpd. No. 1 | CHEMBL3581655)
Affinity DataKi:  70nM ΔG°:  -40.8kJ/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent