Compile Data Set for Download or QSAR
Report error Found 15 of ki for monomerid = 50296345
TargetMuscarinic acetylcholine receptor M4(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.00780nMAssay Description:Displacement of [3H]-NMS from human recombinant M4 receptor expressed in CHO cells after 24 hrs by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.00980nMAssay Description:Displacement of [3H]-NMS from human recombinant M3 receptor expressed in CHO cells after 24 hrs by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.0130nMAssay Description:Displacement of [3H]-NMS from human recombinant M1 receptor expressed in CHO cells after 24 hrs by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.0215nMAssay Description:Displacement of [3H]-NMS from human recombinant M2 receptor expressed in CHO cells after 24 hrs by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.0266nMAssay Description:Displacement of [3H]-NMS from human recombinant M5 receptor expressed in CHO cells after 24 hrs by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.0316nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressing CHO-K1 cells incubated for 60 mins or 6 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.0510nMAssay Description:Antagonist activity at human recombinant M3 receptor expressed in CHO-K1 cells assessed as inhibition of carbamoyl choline-induced calcium currents a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.0610nMAssay Description:Displacement of [3H]-NMS from human recombinant M2 receptor expressed in CHO cells after 2 hrs by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.0750nMAssay Description:Displacement of [3H]-NMS from human recombinant M3 receptor expressed in CHO cells after 2 hrs by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity to muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M2 receptor in heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M1 receptor in cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296345BDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-NMS from Sprague-Dawley rat muscarinic M3 receptor in submandibular glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed