Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = '1,4-dihydroxy-2-naphthoyl-CoA synthase' and Ligand = 'BDBM50382339'
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandPNGBDBM50382339(CHEMBL2024338)
Affinity DataKi:  97nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandPNGBDBM50382339(CHEMBL2024338)
Affinity DataIC50: 103nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandPNGBDBM50382339(CHEMBL2024338)
Affinity DataKi:  792nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed