Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = '3-hydroxyacyl-CoA dehydrogenase type-2' and Ligand = 'BDBM232927'
Target3-hydroxyacyl-CoA dehydrogenase type-2(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)
Affinity DataKi:  1.49E+4nM ΔG°:  -27.5kJ/mole IC50:  5.27E+4nM Kd:  291nMpH: 7.4 T: 2°CAssay Description:The interactions between compounds and ABAD were performed using the dual flow cell BIACORE 3000 instrument. Surface Plasmon Resonance (SPR) studies ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-hydroxyacyl-CoA dehydrogenase type-2(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)
Affinity DataKi:  7.06E+4nM ΔG°:  -23.7kJ/mole IC50:  2.59E+5nMpH: 7.3 T: 2°CAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent