Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2' and Ligand = 'BDBM50401395'
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401395(CHEMBL2206440)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilization i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401395(CHEMBL2206440)
Affinity DataEC50:  209nMAssay Description:Agonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mobilization i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401395(CHEMBL2206440)
Affinity DataEC50:  19nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401395(CHEMBL2206440)
Affinity DataEC50:  19nMAssay Description:Positive modulator activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells co-expressing Gqo5 assessed as increase in intracellular Ca2+ mob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401395(CHEMBL2206440)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/Metabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401395(CHEMBL2206440)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human 5HT2A/mGlu2 receptor expressed in HEK293 cells assessed as inhibition of 5HT-induced intracellular Ca2+ mobilization inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed