Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM50253281'
Target5-hydroxytryptamine receptor 7(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.110nMAssay Description:The new compounds have been tested by radioligand binding competition activity at the human 5-HT1A (FAST-0500B), 5-HT2A (FAST-0505B), 5-HT2Cedited (F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
US Patent

Target5-hydroxytryptamine receptor 7(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataIC50: 0.160nMAssay Description:The new compounds have been tested by radioligand binding competition activity at the human 5-HT1A (FAST-0500B), 5-HT2A (FAST-0505B), 5-HT2Cedited (F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
US Patent

Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity to rat cloned 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity to rat 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]5-CT from human 5HT7 receptor transfected in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-LSD from human 5-HT7 receptor after 1.5 hrs by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Guinea pig)
Università

Curated by ChEMBL
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataEC50:  600nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed