Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM50288848'
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-fused ALK L1196M mutant expressed in Sf9 insect cells using Tyr 1 peptide as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-fused ALK R1275Q mutant expressed in Sf9 insect cells using Tyr 1 peptide as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-fused ALK F1174L mutant expressed in Sf9 insect cells using Tyr 1 peptide as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-fused ALK C1156Y mutant expressed in Sf9 insect cells using Tyr 1 peptide as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of recombinant human wild-type GST-tagged ALK expressed in Baculovirus expression system using Tyr 1 peptide as substrate after 1 hr by Z-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed