Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Aldehyde dehydrogenase, mitochondrial' and Ligand = 'BDBM22794'
TargetAldehyde dehydrogenase, mitochondrial(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22794(1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of human ALDH2 using propionaldehyde as substrate preincubated for 2 mins followed by substrate addition by spectrophotometry in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldehyde dehydrogenase, mitochondrial(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22794(1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...)
Affinity DataKi:  1.50E+4nMAssay Description:Competitive inhibition of human ALDH2 using propionaldehyde as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldehyde dehydrogenase, mitochondrial(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22794(1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...)
Affinity DataKi:  3.40E+4nMAssay Description:Noncompetitive/mixed type inhibition of human ALDH2 by Lineweaver-Burk plot analysis in presence of NAD+More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)