Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor' and Ligand = 'BDBM50019492'
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Dublin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019492BDBM50019492(RX821002 | CHEMBL10332 | 2-(2-methoxy-2,3-dihydrob...)
Affinity DataKi:  0.912nMAssay Description:Displacement of [3H]RX821002 from alpha2 adrenoceptor in human prefrontal cortex neural membrane after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Dublin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019492BDBM50019492(RX821002 | CHEMBL10332 | 2-(2-methoxy-2,3-dihydrob...)
Affinity DataKi:  0.912nMAssay Description:Displacement of [3H]RX821002 from adrenergic alpha2 receptor in human brain frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Dublin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019492BDBM50019492(RX821002 | CHEMBL10332 | 2-(2-methoxy-2,3-dihydrob...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]RX821002 from alpha-2 adrenergic receptor in human brain pre-frontal cortex neural membranes after 30 mins by liquid scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
University of Dublin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019492BDBM50019492(RX821002 | CHEMBL10332 | 2-(2-methoxy-2,3-dihydrob...)
Affinity DataEC50:  8.72E+4nMAssay Description:Antagonist activity at adrenergic alpha 2 receptor in human brain membrane assessed as inhibition of UK14304-induced stimulation of [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed