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Report error Found 6 Enz. Inhib. hit(s) with Target = 'Aminopeptidase N' and Ligand = 'BDBM50336495'
TargetAminopeptidase N(Human)
Merck Sharpe and Dohme

Curated by ChEMBL
LigandPNGBDBM50336495(7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human aminopeptidase N by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Upper Alsace

Curated by ChEMBL
LigandPNGBDBM50336495(7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of porcine kidney APN using L-leucine-p-nitroanilide as substrate after 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Upper Alsace

Curated by ChEMBL
LigandPNGBDBM50336495(7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of pig APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Upper Alsace

Curated by ChEMBL
LigandPNGBDBM50336495(7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of porcine kidney APN using L-leucine para-notroanilide as substrate assessed as release of para-nitroaniline by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAminopeptidase N(Mouse)
University of Upper Alsace

Curated by ChEMBL
LigandPNGBDBM50336495(7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of mouse APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Merck Sharpe and Dohme

Curated by ChEMBL
LigandPNGBDBM50336495(7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed