Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM156378'
TargetApoptosis regulator Bcl-2(Human)
Astrazeneca

US Patent
LigandPNGBDBM156378(US9018381, 3 | US9248140, 3)
Affinity DataIC50: 0.300nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Astrazeneca

US Patent
LigandPNGBDBM156378(US9018381, 3 | US9248140, 3)
Affinity DataIC50: 3.90nMAssay Description:Displacement of synthetic peptide tracer conjugated to fluorescein isothiocyanate from C-terminal 6xHis-tagged Bcl-2 (1 to 204 residues) (unknown ori...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed