Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM31837'
TargetAurora kinase B(Human)
Harvard Medical School

LigandPNGBDBM31837(Aurora Inhibitor, 35 | 2,4-Bisanilinopyrimidine, 1...)
Affinity DataIC50: 1.38E+3nMAssay Description:In vitro kinase assay of Aurora A, B, and C using Z-LYTE technology (Invitrogen) and ATP at Km apparent for each kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2012
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Harvard Medical School

LigandPNGBDBM31837(Aurora Inhibitor, 35 | 2,4-Bisanilinopyrimidine, 1...)
Affinity DataIC50: 3.40E+3nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed