Compile Data Set for Download or QSAR
Report error Found 1 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1 [22-454]' and Ligand = 'BDBM16291'
TargetBeta-secretase 1 [22-454](Human)
Sunesis

LigandPNGBDBM16291(N -[(1S,2S,4R)-2-amino-1-benzyl-5-{[(1S)-1-(benzyl...)
Affinity DataKi:  33nM ΔG°:  -42.3kJ/molepH: 4.5 T: 2°CAssay Description:Compounds were tested for their ability to inhibit BACE-1 hydrolysis of the internally quenched fluorescent substrate FS-2. Reactions were initiated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2007
Entry Details Article
PubMed