Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM116254'
TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 116254BDBM116254(US8637508, 31 | US10035794, Example 31 | US1068328...)
Affinity DataIC50: 1nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 116254BDBM116254(US8637508, 31 | US10035794, Example 31 | US1068328...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant BACE2 catalytic domain using FRET substrate with BACE-cleavable sequenceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 116254BDBM116254(US8637508, 31 | US10035794, Example 31 | US1068328...)
Affinity DataIC50: 1nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 116254BDBM116254(US8637508, 31 | US10035794, Example 31 | US1068328...)
Affinity DataIC50: 1nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent