Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Bifunctional dihydrofolate reductase-thymidylate synthase' and Ligand = 'BDBM31783'
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandChemical structure of BindingDB Monomer ID 31783BDBM31783(thieno[2,3-d]pyrimidine deriv., 2f)
Affinity DataIC50: 14nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandChemical structure of BindingDB Monomer ID 31783BDBM31783(thieno[2,3-d]pyrimidine deriv., 2f)
Affinity DataIC50: 1.60E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed