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Found 2 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50015421'
TargetBile acid receptor(Homo sapiens (Human))
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50015421(CHEMBL3264644)
Affinity DataIC50:  7.5nMAssay Description:Antagonist activity at human GST-tagged FXR after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50015421(CHEMBL3264644)
Affinity DataIC50:  469nMAssay Description:Inhibition of GW4064-induced transactivation of FXR (unknown origin) expressed in HEK293T cells after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed