Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50226465'
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory concentration against Farnesoid X receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 4.10E+4nMAssay Description:Antagonist activity at human FXR expressed in HEK293 cells assessed as inhibition of GW4064-induced transactivation after 24 hrs by luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 4.40E+4nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Farnesoid X receptor; range from 50-100000More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed