Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Botulinum neurotoxin type E' and Ligand = 'BDBM50189883'
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50189883(CHEMBL1999371)
Affinity DataKi:  1.29E+3nMAssay Description:Inhibition of protease activity of Clostridium botulinum BoNT/E light chain using SNAP-25 as substrate after 15 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2017
Entry Details Article
PubMed
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50189883(CHEMBL1999371)
Affinity DataKi:  1.29E+3nMAssay Description:Inhibition of protease activity of Clostridium botulinum BoNT/E using SNAP-25 as substrate after 15 mins by HPLC based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetBotulinum neurotoxin type E(Clostridium botulinum)
Brookhaven National Laboratory

Curated by ChEMBL
LigandPNGBDBM50189883(CHEMBL1999371)
Affinity DataIC50: 4.85E+4nMAssay Description:Inhibition of Clostridium botulinum BoNT/E light chain using GFP-tagged VAMP2/SNAP-25 (Ala128 to Gly206 residues) as substrate after 15 mins by GFP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed