Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 5' and Ligand = 'BDBM50339033'
TargetC-C chemokine receptor type 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50339033(5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)...)
Affinity DataKd:  3.10nMAssay Description:Activation of CCR5 in human PBMC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50339033(5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)...)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at CCR5 assessed as inhibition of receptor internalizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50339033(5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at CCR5 in IL-10 stimulated human PBMC cells assessed as MIP-1beta induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50339033(5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at CCR5 assessed as inhibition of ERK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50339033(5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)...)
Affinity DataIC50: 3.10nMAssay Description:Binding affinity to CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50339033(5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)...)
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 in IL-10-stimulated human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50339033(5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CCR5 assessed as inhibition of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed