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Report error Found 28 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM26999'
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  7nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated with enzyme for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nM ΔG°:  -45.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human CA2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant Carbonic anhydrase 2 compound preincubated for 15 mins by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase-2 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human Carbonic anhydrase2 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase 2 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant carbonic anhydrase-2 by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase-2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ege University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26999BDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  664nMAssay Description:Inhibition of full length Mycobacterium tuberculosis H37Rv recombinant carbonic anhydrase 2 encoded by RV3588c by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed