Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM50080733'
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  6nMAssay Description:Inhibition of human carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against human carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  33nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human recombinant carbonic anhydrase-2 by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human carbonic anhydrase 2 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibitory activity against human carbonic anhydrase II (hCA II) by using esterase assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human carbonic anhydrase-2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human recombinant Carbonic anhydrase 2 compound preincubated for 15 mins by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  125nMAssay Description:Inhibition of human carbonic anhydrase-2 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  125nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  125nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  125nMAssay Description:Inhibition of human Carbonic anhydrase2 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080733BDBM50080733(4-(4-aminophenylsulfonamido)-1-benzenesulfonamide ...)
Affinity DataKi:  1.66E+8nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed