Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Caspase-1' and Ligand = 'BDBM166683'
TargetCaspase-1(Human)
Depaul University

LigandPNGBDBM166683(U74389G (B9))
Affinity DataIC50: 174nMpH: 7.5 T: 2°CAssay Description:All assays were performed at 100 µL total volume in triplicate and monitored for 60 minutes at room temperature in a 96-well plate format in HEPES Bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetCaspase-1(Human)
Depaul University

LigandPNGBDBM166683(U74389G (B9))
Affinity DataIC50: 174nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-1 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetCaspase-1(Human)
Depaul University

LigandPNGBDBM166683(U74389G (B9))
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant DTT-activated caspase-1 expressed in Escherichia coli using WEHD-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetCaspase-1(Human)
Depaul University

LigandPNGBDBM166683(U74389G (B9))
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DTT-activated caspase-1 expressed in Escherichia coli using Ac-WEHD-AMC as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetCaspase-1(Human)
Depaul University

LigandPNGBDBM166683(U74389G (B9))
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed