Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM160808'
TargetCaspase-3(Human)
Novagenesis Foundation

US Patent
LigandPNGBDBM160808(US9045524, 76 | US10167313, Compound 76)
Affinity DataIC50: 30nMAssay Description:To test the efficacy of caspase-3 inhibitors at the cellular level, the ability of selected compounds to inhibit the proteolytic cleavage of PARP (po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetCaspase-3(Human)
Novagenesis Foundation

US Patent
LigandPNGBDBM160808(US9045524, 76 | US10167313, Compound 76)
Affinity DataIC50: 30nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent