Compile Data Set for Download or QSAR
Report error Found 1 Enz. Inhib. hit(s) with Target = 'Cathepsin D' and Ligand = 'BDBM17786'
TargetCathepsin D(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17786((4S)-4-(2-amino-6-phenoxy-3,4-dihydroquinazolin-3-...)
Affinity DataIC50: 110nMpH: 4.0 T: 2°CAssay Description:Cathepsin D activity was measured at pH 4 using a FRET peptide substrate. Compounds were preincubated with recombinant human liver cathepsin D for 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2007
Entry Details Article
PubMed