Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 1A1' and Ligand = 'BDBM50452361'
TargetCytochrome P450 1A1(Human)
De Montfort University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452361BDBM50452361(CHEMBL4218749)
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in HEK293 cells using 7-ethoxyresorufin as substrate pretreated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
De Montfort University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452361BDBM50452361(CHEMBL4218749)
Affinity DataIC50: 61nMAssay Description:Inhibition of human CYP1A1 expressed in yeast microsomal membranes using 7-ethoxyresorufin as substrate measured after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
De Montfort University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452361BDBM50452361(CHEMBL4218749)
Affinity DataIC50: 150nMAssay Description:Inhibition of human CYP1A1 expressed in yeast cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
De Montfort University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452361BDBM50452361(CHEMBL4218749)
Affinity DataKi:  280nMAssay Description:Competitive inhibition of human CYP1A1 using 7-ethoxyresorufin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
De Montfort University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452361BDBM50452361(CHEMBL4218749)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in HEK293 cells assessed as reduction in benzo(a)pyrene-induced toxicity by measuring B[a]P EC50 at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed