Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50061669'
TargetD(2) dopamine receptor(Human)
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at human dopamine D2L receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  0.160nMAssay Description:Agonistic activity towards dopamine D2 receptor using radioligand [3H]quinpirole in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  0.200nMAssay Description:Affinity of compound for Dopamine receptor D2 in rat striatal membrane determined for antagonist state (low affinity state, D2 Low) with [3H]spiperon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  0.200nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  0.200nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  2.98nMAssay Description:Displacement of [3H]spiperone from high-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]spiperone from high-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  3.30nMAssay Description:In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]spiperone radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  3.30nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  3.30nMAssay Description:Antagonistic activity towards dopamine D2 receptor using radioligand [3H]spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  3.30nMAssay Description:Affinity of compound for Dopamine receptor D2 in rat striatal membrane determined for antagonist state (low affinity state, D2 Low) with [3H]spiperon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards human cloned dopamine (hD2s) receptors expressed in CHO cell membranes using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  10nMAssay Description:Affinity for the Dopamine receptor D2S was determined using membranes from CHO cells labeled with [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  10nMAssay Description:Binding affinity at human Dopamine receptor D2 (hD2) using [3H]spiperone radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]spiperone from low-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  70.2nMAssay Description:Displacement of [3H]spiperone from low-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  736nMAssay Description:Displacement of [3H]spiperone from low-affinity state of human dopamine D2S receptor transfected in HEK293 cells after 2 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Amsterdam

Curated by ChEMBL
LigandPNGBDBM50061669(CHEMBL64553 | CHEMBL134807 | (R)-2-(Benzylamino-me...)
Affinity DataKi:  736nMAssay Description:Displacement of [3H]spiperone from low-affinity state of human dopamine D2S receptor transfected in HEK293 cells after 2 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed